GL50803_8961

Species: G.lamblia
Alias: GL50803_8961, GK191
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_8961.AA Protein None 968 None Fasta, JSON
GL50803_8961.kin_dom Protein Kinase Domain None 214 None Fasta, JSON

Protein domain

Protein domains of GL50803_8961.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_8961.AA NRBP 86-227 25 6e-06 16.62 In-house 111-261 (261) Show / Hide
Range on Protein: 86-227
Range on HMM: 111-261/261
Sequence Identity: 25% (39 aa)

QIVDALVYLHVPFKPHGVIVNGSLSTSTVLIDQH--MNIRMLLPGMTRSQIEKWLYSDAPELVIPNRYMVHKNVYLSTKVDIWSLGKILLDLATLGTG--
||. || |||    |   |. | | . |. | .   . |    |   .... .          ..  | . ..  | | |||.| |   |..| |.    
QILSALSYLHSCDPP---IIHGNLTCDTIFIQHNGLIKIGCVWPDAIHHHVRTCREEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCALEMAVLEIQSG

-LSSLTK-------QPHFAAVYPQWISETIFRSLSLDPAERPSAIHLLHIPELK
   . ..       |    ..  .   . | . |  |||.|||| .||  . | 
CQNGESEYVTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF

Kinase GL50803_8961.AA CDK-Unclassified 201-226 19 5.1e-05 12.29 In-house 299-324 (324) Show / Hide
Range on Protein: 201-226
Range on HMM: 299-324/324
Sequence Identity: 19% (5 aa)

ETIFRSLSLDPAERPSAIHLLHIPEL
...|  ....| .|...  .|. |..
NCEFQMVMYQPYNRWKCMEILQHPWF

S_TKc GL50803_8961.AA S_TKc 13-226 15 0.000207 -112.24 SMART 1-231 (231) Show / Hide
Range on Protein: 13-226
Range on HMM: 1-231/231
Sequence Identity: 15% (41 aa)

EIDIEDLANDGFCTCTEEYTPD------------QPLTHKLLLECTSMHRDFTDFEDSLT-----------------LQRYLTNRRL--SREPLSADQIA
   .. .   .| ..   .  .            . .    .|.    |     . |.                   | .|. .|.    | |..  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

FIFEQIVDALVYLHVPF------KPHGVIVNGSLSTSTVLIDQHMNIRMLLPGMTRSQIEKWLYSDAPELVIPNRYMVHKNVYLST-KVDIWSLGKILLD
|.. ||..|| |.|         ||  . ..        ..|  .  ..    .|      ..   |||..             .. |.|.||.| ||  
FYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYM---APEVL-----------GYGKCKCDWWSCGCILYE

LAT----LGTGLSSLTKQPHFAAVYPQWISETIFRSLSLDPAERPSAIHLLH-------IPEL
...        .  . |.       |. ..  | . |  ||..||.|  .|.        | .
MLCGYPPFP-QMQMMFKKIG----SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_8961.AA SgK071 160-177 66 0.00036 10.39 In-house 199-216 (283) Show / Hide
Range on Protein: 160-177
Range on HMM: 199-216/283
Sequence Identity: 66% (12 aa)

STKVDIWSLGKILLDLAT
|.| |||||| |.|| .|
SQKSDIWSLGCIILDMTT

Kinase GL50803_8961.AA Ciliate-E2-Unclassified 59-95 21 0.000369 10.35 In-house 106-160 (352) Show / Hide
Range on Protein: 59-95
Range on HMM: 106-160/352
Sequence Identity: 21% (12 aa)

LTLQRYLT-------------NRRLSREPLSADQIA-----FIFEQIVDALVYLH
..|. |..             .....|. ..  |..     |.| ||...| |||
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH

Kinase GL50803_8961.AA NEK8 207-226 40 0.000839 6.6 In-house 259-278 (278) Show / Hide
Range on Protein: 207-226
Range on HMM: 259-278/278
Sequence Identity: 40% (8 aa)

LSLDPAERPSAIHLLHIPEL
|..||. |||| ...  | .
LQQDPEQRPSASQIMAMPLC

Kinase GL50803_8961.AA CDK-Unclassified 72-95 37 0.138988 0.82 In-house 115-138 (324) Show / Hide
Range on Protein: 72-95
Range on HMM: 115-138/324
Sequence Identity: 37% (9 aa)

REPLSADQIAFIFEQIVDALVYLH
| .||  ||   . |..  ..|||
RYNLSMCQIRNFMHQMLEGIAYLH

Ank GL50803_8961.AA Ank 388-410 34 0.001113 17.53 Pfam 1-23 (33) Show / Hide
Range on Protein: 388-410
Range on HMM: 1-23/33
Sequence Identity: 34% (8 aa)

NGHTALMMAAYRGYDTCVRILLN
.| |.|..|...|.  .|. ||.
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_8961.AA Ank 417-437 33 2.919093 5.2 Pfam 1-21 (33) Show / Hide
Range on Protein: 417-437
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

TESSALLLAMMSGHYKCIKLL
   ..| || ..||....|.|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_8961.AA Ank 444-458 33 0.243637 9.09 Pfam 1-15 (33) Show / Hide
Range on Protein: 444-458
Range on HMM: 1-15/33
Sequence Identity: 33% (5 aa)

NGVTPLMYYASLGNV
.| |||..... |..
DGFTPLHLACRCGHT

Ank GL50803_8961.AA Ank 480-506 37 0.018833 13.1 Pfam 1-25 (33) Show / Hide
Range on Protein: 480-506
Range on HMM: 1-25/33
Sequence Identity: 37% (10 aa)

TGWTALMFAAAGGFTLCVNLLLADEQG
 |.|.|. |.  | | .| .||   .|
DGFTPLHLACRCGHTEVVKMLLQ--HG

Ank GL50803_8961.AA Ank 511-535 36 2e-06 27.22 Pfam 1-25 (33) Show / Hide
Range on Protein: 511-535
Range on HMM: 1-25/33
Sequence Identity: 36% (9 aa)

NGETALMKAASRNNNNVIQLLLQQG
.|.|.|. |..... .|...|||.|
DGFTPLHLACRCGHTEVVKMLLQHG

Ank GL50803_8961.AA Ank 545-568 41 0.026927 12.54 Pfam 1-24 (33) Show / Hide
Range on Protein: 545-568
Range on HMM: 1-24/33
Sequence Identity: 41% (10 aa)

DGRTALMIAVQNTALESVLLLQQH
||.|.|..|...  .| | .| ||
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_8961.AA Ank 638-668 33 3e-05 23.19 Pfam 1-33 (33) Show / Hide
Range on Protein: 638-668
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

SGATALMHAAQNGHHGCVRYLLG--KELGMQDR
 | |.|. |...||. .|..||.   .. .||.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_8961.AA Ank 607-637 30 0.002739 16.12 Pfam 1-33 (33) Show / Hide
Range on Protein: 607-637
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

FGLTALMYAAMSGYCDCVQLLAT--SEAGAQDE
 | |.|..|...|. ..|..|     .  ||| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_8961.AA Ank 669-691 30 0.033242 12.21 Pfam 1-23 (33) Show / Hide
Range on Protein: 669-691
Range on HMM: 1-23/33
Sequence Identity: 30% (7 aa)

TGWTALMWATQGNYATCVKEILD
 |.|.|..| . ... .||. |.
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_8961.AA Ank 576-606 24 0.243637 9.09 Pfam 1-33 (33) Show / Hide
Range on Protein: 576-606
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

SGVTALMFAAQGGFAEAITILYS--TETGIKDS
 | |.|. |.. | .| .. | .   .  ..| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_8961.AA Ank 746-766 28 0.000337 19.4 Pfam 1-21 (33) Show / Hide
Range on Protein: 746-766
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

NGSTALMIAAQKNHLSCAQLL
.| |.|..|....|......|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_8961.AA Ank 777-799 30 0.01575 13.38 Pfam 1-23 (33) Show / Hide
Range on Protein: 777-799
Range on HMM: 1-23/33
Sequence Identity: 30% (7 aa)

SGSTALMRAAFSGASDIALLLLE
 | |.|. |...|  ... .||.
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_8961.AA Ank 808-829 36 0.00121 17.4 Pfam 1-22 (33) Show / Hide
Range on Protein: 808-829
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

DGLTALMYAAQAGMDLCVQLLI
|| |.|..|.. |   .|..|.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_8961.AA Ank 839-860 36 0.000913 17.84 Pfam 1-22 (33) Show / Hide
Range on Protein: 839-860
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

GGKTALMLAAQARHPNCVRALI
 | |.|.||..  |...|. |.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_8961.AA Ank 911-933 26 32.774066 1.41 Pfam 1-23 (33) Show / Hide
Range on Protein: 911-933
Range on HMM: 1-23/33
Sequence Identity: 26% (6 aa)

AGWPALFYAVVSGDSISASLLLE
 |. .| .|. .|.   ...||.
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_8961.AA Ank 942-960 36 0.046925 11.67 Pfam 1-19 (33) Show / Hide
Range on Protein: 942-960
Range on HMM: 1-19/33
Sequence Identity: 36% (7 aa)

QGQTALDLAAERGDLELIE
 |.|.| ||...|..| ..
DGFTPLHLACRCGHTEVVK