Gene GL50803_91451 (G.lamblia)

GL50803_91451

Species: G.lamblia
Alias: GK217, GL50803_91451
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_91451.AA Protein None 750 None Fasta, JSON
GL50803_91451.kin_dom Protein Kinase Domain None 274 None Fasta, JSON

Protein domain

Protein domains of GL50803_91451.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase GL50803_91451.AA Pkinase 8-281 26 2.8e-66 231.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-293/293
Sequence Identity: 26% (83 aa)

YFEIGKIATGGFATIYRAVDLETGLVVALKDTIYNCSSRSATKAMRR--EIAILRNIQHCNIVRCYDIQRATEESRYFISMELCNC-----DLHDFIRAF
|  ..||  |.|.. |....  || .||.|   .   . .  .. ||  ||.|.....|.||||.||. .   .... . ||.|..     ||.|.|.. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

RHKRRRI--PEATVLTMIKDIASALAFLHNPINFTTIDSLDADEDSIRVIIHRDVKPGNIMLANDGFF----KLCDFNLARE--INTVTGAMSNTGTIAY
 ......  .| ..  ... |...|...|.                   |||||.|| ||.. |.|      |.||| ||.   .   . ... .||. |
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM-----------------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY

MAPELLD-GKKYDEKVDLWSLGCTIHEMCMYYSPFHNQ------SITQALNNIMMGRYDSICNFYS--------------------ERLRKLVQMLLSIN
||||..  |..|. ||| ||.||...||.  . || ..      .  | ...||...... .   .                    | .....  .|  .
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

PLDRPSAAELLGHPLL
| .||.|...| || .
PKKRPTAEQILQHPWF
S_TKc GL50803_91451.AA S_TKc 8-281 29 3.5e-64 220.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-231/231
Sequence Identity: 29% (85 aa)

YFEIGKIATGGFATIYRAVDLETGLVVALKDTIYNCSSRSATKAMRREIAILRNIQHCNIVRCYDIQRATEESRYFISMELCNC---DLHDFIRAFRHKR
|  . ||  |.|.. |.... .|| .||.|            . .||||.||.. .| |||..||. .    ..... ||.|.    ||.|.|.  ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

RR--IPEATVLTMIKDIASALAFLHNPINFTTIDSLDADEDSIRVIIHRDVKPGNIMLANDGFFKLCDFNLAREINTVTGAMSNTGTIAYMAPELLDGKK
.|  .|| ..  ... |..||...|.                 . |||||.|| ||.| .    |.||| |||..      ..  ||  |||||.|   .
LRFPFPE-HARFYMYQICCALEYCHS-----------------HGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---G

YDE-KVDLWSLGCTIHEMCMYYSPFHNQSITQALNNIMMGRYDSICNFYSERLRKLVQMLLSINPLDRPSAAELLG-------HPLL
|.  |.| ||.||.. ||.  | ||.   . . ...|.           |. .. ... .|  .| .||.| |.|        || .
YGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_91451.AA NEK 8-281 27 3.7e-59 202.87 In-house 1-286 (286) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-286/286
Sequence Identity: 27% (84 aa)

YFEIGKIATGGFATIYRAVDLETGLV-----VALKDTIYNCSSRSATKAMR-REIAILRNIQHCNIVRCYDIQRATEESRYFISMELCN--CDLHDF---
| .| ||  | | . |.. . ..| .     ...|   ... |.  ...    |. ||. ..| |||. ||     . .. .| || |.   ||...   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IRAFRHKRRRIPEATVLTMIKDIASALAFLH---NPINFTTIDSLDADEDSIRVIIHRDVKPGNIMLANDG----FFKLCDFNLAREIN-TVTGAMS-NT
|   ..|.  ..| ... .   ...|| ..|   .|                | |.||| || ||.| ...    . |. ||..... | |.. | .  .
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGP---------------QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQV

GTIAYMAPELLDGKKYDEKVDLWSLGCTIHEMCMYYS--PFHNQ--SITQALNNIMMG-RYDSICNF--YSERLRKLVQMLLSINPLDRPSAAELLGHPL
||  ||.||.. .|.|..|.| ||||| . |||.  .  ||  .  .. .  ..|| |  |. |  .  ||. |..|....|  .| .|||. ..| .|.
GTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPF

L
.
I
Kinase GL50803_91451.AA NEK2 55-281 31 6.7e-45 149.07 In-house 48-319 (319) Show / Hide 
Range on Protein: 55-281
Range on HMM: 48-319/319
Sequence Identity: 31% (85 aa)

EIAILRNIQHCNIVRCYDIQRATEESRYFISMELCNC-DLHDFIRAFRHKRRRIPEATVLTMIKDIASALAFLHN----PINFTTIDSLDADEDSIRVII
|. |||  .| |||| ||     ..|.  | || |   ||   |   |  |....|  ..     . .||   ||    |   |  | .    |  ..|.
ECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTIL

HRDVKPGNIMLANDGF---------------------------------------FKLCDFNLAREIN-TVTGAMSNTGTIAYMAPELLDGKKYDEKVDL
||| ||.|| |  |.                                         || || |||  |     | .  ||  || ||.. | ||.|| | 
HRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDI

WSLGCTIHEMCMYYSPFHNQSITQALNNIMMGRYDSICNFYSERLRKLVQMLLSINPLDRPSAAELLGHPLL
||.|| | |||    ||   .  |    |  |... |   ||. | ...   . ...  |||  |.|.||..
WSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase GL50803_91451.AA STE 148-281 25 6.3e-38 131.53 In-house 173-359 (359) Show / Hide 
Range on Protein: 148-281
Range on HMM: 173-359/359
Sequence Identity: 25% (49 aa)

IIHRDVKPGNIMLANDGFFKLCDFNLAREINT-----------------VTGAMSNTGTIAYMAPELLDG------KKYDEKVDLWSLGCTIHEMCMYYS
|||||.||.||.|      ||||| ..  ..                  .    . .||  .|||| ...      |.||.|.| ||||||| ||.    
IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP

PFHNQSITQALNNIMMG---------------RYDSICN-------------------FYSERLRKLVQMLLSINPLDRPSAAELLG--HPLL
|.|. . ..|. .|...                  .. .                    .|. ..  ..  | ..| .||.| .||   || .
PWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_91451.AA Ciliate-E2 148-281 23 1.1e-34 116.49 In-house 182-365 (365) Show / Hide 
Range on Protein: 148-281
Range on HMM: 182-365/365
Sequence Identity: 23% (46 aa)

IIHRDVKPGNIMLANDGFFKLCDFNLAREINTV---------TGAMSNTG------------------------TIAYMAPELLDGKK---------YDE
||||| || ||..      |..|| |......           . . . .                        |  ||||| | |||         ||.
IIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDY

KVDLWSLGCTIHEMCMYYSPFHNQSITQALNNIMMGRYDSICNF-----------------YSERLRKLVQM----LLSINPLDRPS-AAELLGHPLL
|.|.||||....||.. . ||        ...|. . .|  |..                  |.    | .     .|  .|  |.. . ..| || .
KCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_91451.AA CAMK 148-281 20 4.1e-34 106.8 In-house 200-425 (425) Show / Hide 
Range on Protein: 148-281
Range on HMM: 200-425/425
Sequence Identity: 20% (46 aa)

IIHRDVKPGNIMLAND-----------------GFFKLCDFNLAREINTVTG------------------------AMSNTGTIAYMA-PELLDGKK---
|.||| || ||.| ..                 .  |..|| .|....   .                             || .||| ||.| ||.   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YDEKVDLWSLGCTIHEMCMYYSPFHNQSITQALN-------------NIMMGRYDSICNF-----------------------YSERLR
           |..|.| ||.|.    |   |.||   .  . ..             .|| |.|| .  .                        |.  .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

KLVQMLLSINPLDRPSAAELLGHPLL
 |.. .|  .| .|..... | || .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_91451.AA Ciliate-E2-Unclassified 148-281 25 1.5e-32 110.28 In-house 165-352 (352) Show / Hide 
Range on Protein: 148-281
Range on HMM: 165-352/352
Sequence Identity: 25% (47 aa)

IIHRDVKPGNIMLANDG---FFKLCDFNLAREINTVTG----------------AMSNTGTIAYM----APELLDGKKYD----EKVDLWSLGCTIHEMC
||||| || ||.. |.|     |..|| .......  .                . ...||. ||    |||.|.|..||    .|.| ||||. ..||.
IIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEML

MYYSPFHNQSITQ----------------ALNNIMMGRYDSIC-NF------YSERLRKLVQ----MLLSINPLDRPSAAELLGHPLL
. | ||  .. .|                 ..||. . ..  . ..       |.    ...     .|  ||  |... ..| ||..
FGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_91451.AA ULK 148-281 26 4.2e-27 91.72 In-house 151-329 (329) Show / Hide 
Range on Protein: 148-281
Range on HMM: 151-329/329
Sequence Identity: 26% (48 aa)

IIHRDVKPGNIMLAND------------GFFKLCDFNLAREINT----VTGAMSNT------GTIAYMAPELLD----GKKYD-EKVDLWSLGCTIHEMC
||||| || ||.. |.            | .|..|| .|. ..        .|. .      ||  ||||..|     .|.|.  |.|.||||| ..|| 
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

MYYSPFHNQSITQALNNIMMGRYD-----------SICNFY--------SERLRKLVQMLLSINPLDRPSAAELLGHPLL
  . || .. ...  ..|..  ..              .|.        |. .. | . .| ... || |  ||. ||..
YGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_91451.AA ULK 148-281 26 2.7e-24 83.17 In-house 147-324 (324) Show / Hide 
Range on Protein: 148-281
Range on HMM: 147-324/324
Sequence Identity: 26% (47 aa)

IIHRDVKPGNIMLAND------------GFFKLCDFNLAREINT-VTGAMSNT---------GTIAYMAPELLD----GKKYD-EKVDLWSLGCTIHEMC
||||| || ||.. |.            | .|..|| .|. ..     .. ..         ||  ||||..|     .|.|.  |.|.||||| ..|| 
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

MYYSPFHNQSITQAL----NNIMMG------RYDSICNFY--------SERLRKLVQMLLSINPLDRPSAAELLGHPLL
  . || .. ...      . | .|       ..   .|.        |. .. | . .| ... || |  |.. ||..
YGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_91451.AA CAMKL 148-281 33 4.3e-24 73.64 In-house 148-297 (297) Show / Hide 
Range on Protein: 148-281
Range on HMM: 148-297/297
Sequence Identity: 33% (51 aa)

IIHRDVKPGNIMLANDG--FFKLCDFNLAREIN---TVTGAMSNT--GTIAYMAPELLDG--KKYD-EKVDLWSLGCTIHEMCMYYSPFHNQ--------
|.||| || ||.| ..|    |..|| .. ..      .| . .|  |. .|||||.. |  |.||  ||| ||.| .   |   | || ..        
IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKD

SITQALNNIMMGRYDS-ICNFYSERLRKLVQMLLSINPLDRPSAAELLGHPLL
 |   .. || | |   | .. | ..| | . .|  || .||.. ... || .
NI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase GL50803_91451.AA CAMK 13-128 15 1.9e-22 68.48 In-house 1-197 (425) Show / Hide 
Range on Protein: 13-128
Range on HMM: 1-197/425
Sequence Identity: 15% (30 aa)

KIATGGFATIYRAVDLETG------------LVVALKDTIYNCS----------------------------SRSATKAMRREIAILRN-------IQHC
.. .|.|.. ..... .|.              || |  |.. .                            . .  | .||||.|...       ..| 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIK--IIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHP

NIVRCYDIQR------------ATE------ESRYFISM---ELCNC-----DLHDFIRAFRHKR-----------RRIPEATVLTMIKDIASALAFLHN
||...|..                .      ...... |   |.|       || |.|.. ....           .|..|. . .... |.||....|.
NIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS
Kinase GL50803_91451.AA CMGC 148-219 25 6.7e-22 67.93 In-house 205-328 (513) Show / Hide 
Range on Protein: 148-219
Range on HMM: 205-328/513
Sequence Identity: 25% (31 aa)

IIHRDVKPGNIMLANDGFF--------------------KLCDFNLAREINTV---------------------TGAMS-NTGTIAYMAPELLDG-----
||||| || ||.. ...                      |.||| ||| ...                      . ... .  |  | |||.| |     
IIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYT

-----KKYDEKVDLWSLGCTIHEM
     ..|....| ||.|| . ||
NHNYSMHYTTPIDMWSVGCIFAEM
Kinase GL50803_91451.AA CMGC 8-127 15 3.3e-18 55.58 In-house 1-199 (513) Show / Hide 
Range on Protein: 8-127
Range on HMM: 1-199/513
Sequence Identity: 15% (33 aa)

YFEIGKIATGGFATIYRAVD--------------LETGLVVALK------DTIYNCSSRSATKAMR-----------REIAILRNIQ-------------
|  |.||  | ... |...|               ||. .||.|      ...  .|                    ||| ||....             
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKS--------TIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDP

----HCNIVRCYDIQRATEES---------------RYFISMELCNCDLHDFIRAFRH-----KRRRIPEAT------------VLTMI------KDIAS
    | |||..||| .  ..                  .. .|.. .||...|.  ..     ...  .|              .  ..      . |  
DNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILR

ALA--FLH
.|.  ..|
GLKLKYCH
Kinase GL50803_91451.AA TyrKc 8-281 20 3.9e-17 54.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-280/280
Sequence Identity: 20% (65 aa)

YFEIGKIATGGFATIYRAVDLETGLVVA---LKDTIYNCSSRSATKAMRREIAILRNI--QHCNIVRCYDIQRATEE-----SRYFISMELC-NCDLHDF
   . |.  | | ..|...     . ||   ||.           ....||. |....  .| ||||.| . .  ..       ..| ||.. . ||.|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IRAFRHKRRRIPEATVLTMIKDIASALAFLHNPINFTTIDSLDADEDSIRVIIHRDVKPGNIMLANDGFFKLCDFNLAREINTV--------TGAM----
.|. |.|   .. .. | .  .||.  ..||                    .||||    |.......  | .|| |.|.|           .  .    
LRKHRPK---LCMKDLLSFCWQIACGMEYLHSK-----------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

-SNT-GTIAYMAPELLDGKKYDEKVDLWSLGCTIHEMCMY-YSPFHN-----QSITQALNNIMMGRYDSICNF--------YSERLRKLVQMLLSINPLD
 ..|   |  |||| .. .|. .| | || | .. |.. |  .|  .      | ........ |..  .            .. . .. ..    .| |
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RPSAAELLGHPLL
||. .|.  | ..
RPTFSEI--HECF
Kinase GL50803_91451.AA CAMKL 9-128 25 3.6e-16 47.94 In-house 1-145 (297) Show / Hide 
Range on Protein: 9-128
Range on HMM: 1-145/297
Sequence Identity: 25% (38 aa)

FEIGK-IATGGFATIYRAVD-LETGLVVALKDTIYN---CSSRSATKAM------------RREIAILRNIQ---HCNIVRCYDIQRATEE----SRYFI
..||| . .|.|..   |.. . ||  || |  |..   .. .  .|..            ||||.|.. ..   | ||.. |..    |     . ...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIK--IIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL

SMELCNCD---LHDFIRAFRHKRRRIPEATVLTMIKDIASALAFLHN
 ||.|      |.|.|.. .|.|.|.||     . . | ||....|.
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHS
Kinase GL50803_91451.AA STE 9-128 19 3.7e-14 46.49 In-house 1-170 (359) Show / Hide 
Range on Protein: 9-128
Range on HMM: 1-170/359
Sequence Identity: 19% (33 aa)

FEI-GKIATGGFATIYRAVDLE---------------TGLVVALKDTIYNCSSR----------------SATKAMRREIAILRNIQ--HCNIVRCYDIQ
.|. .||  |.| | |.|.. .               || ..| |  .  ....                .  .   .|| |... .  | |||..|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIK-QMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

R-----ATEESRYFISMELCNC-DLHDFIR-AFRHKR---------RRIPEATVLTMIKDIASA-LAFLHN
        ...  .| ||...   | |.|.  . ...          |.||  . .....|  . |..||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS
Kinase GL50803_91451.AA Ciliate-E2 8-128 20 1.1e-13 43.31 In-house 1-178 (365) Show / Hide 
Range on Protein: 8-128
Range on HMM: 1-178/365
Sequence Identity: 20% (36 aa)

YFEIGKIATGGFATIYRAVDLETGLVVALK--------------DT--IYNCSSR--SATKAMRREIAILRNIQ----------------HCNIVRCYDI
|  | || .|.|...|.. . ...  .|.|              ..  ||.  .   .  ... .|| |.| |.                | ||...|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

QRATEESRYFISMELCNC-DLHDFIRAFRHKR-------RRIPEATVLTMIKDIAS---------------ALAFLHN
   . .. ... ||.|.  || |.|. ...||        .. |  .....| |..               || .||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS
Kinase GL50803_91451.AA ULK 8-128 20 1.3e-13 44.67 In-house 1-144 (324) Show / Hide 
Range on Protein: 8-128
Range on HMM: 1-144/324
Sequence Identity: 20% (30 aa)

YFEIGKIATGGFA-TIYRAVDLET---GLVVALKDTIYNCSSRSATK--------AMRREIAILRNIQ------HCNIVRCYDIQRATEESRYFISMELC
|  . ..  | |. . |.. . .|   . .|| |    .  . .  .          ..|| |.. .       | .||. ||... . .  ..| ||.|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

NC-DLHDFIRAFRH-----KRRRIPEATVLTMIKDIASALAFLHN
|. || ..|   ..     . .|..|  ..  .|.|.... .||.
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK
Kinase GL50803_91451.AA ULK 8-127 21 6.2e-13 41.56 In-house 1-147 (329) Show / Hide 
Range on Protein: 8-127
Range on HMM: 1-147/329
Sequence Identity: 21% (31 aa)

YFEIGKIATGGFATIYRAVDLET----GLVVALKDTIYN-CSSRS-------ATKAMRREIAILRNI--------QHCNIVRCYDIQRATEESRYFISME
|  . ..  | |.. |.. . .|    . .|| |    . ..  .       . .  ..|| |.. .        .|.|||. ||... . .  ..| ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCNC-DLHDFIRAFRH------KRRRIPEATVLTMIKDIASALAFLH
.||  || ..|   ..      . .|..|  ..  .|.|.... .||
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELH
Kinase GL50803_91451.AA Ciliate-E2-Unclassified 8-127 15 3.3e-10 31.61 In-house 1-160 (352) Show / Hide 
Range on Protein: 8-127
Range on HMM: 1-160/352
Sequence Identity: 15% (26 aa)

YFEIGKIATGGFATIYRAVDLETGLVV-----ALKDTIYN-CSSRSATKAMRREIAILRNIQHCNIVR------------------CYDIQRATEESRYF
|  | .| .|||...|.... ...  .     . |  ||. .. ..    . .|. .. |... ...|                   ...   . .   .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

ISMELC-NCDLHDFIRAF-------------RHKRRRIPEATVL-----TMIKDIASALAFLH
| ||.| . ||...|. .             ...|....|  ..     .... | ..| .||
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH
Kinase GL50803_91451.AA Pkinase_Tyr 157-222 30 3e-07 25.18 Pfam 141-210 (270) Show / Hide 
Range on Protein: 157-222
Range on HMM: 141-210/270
Sequence Identity: 30% (22 aa)

NIMLANDGFFKLCDFNLAREI----NT-VTGAMSNTGTIAYMAPELLDGKKYDEKVDLWSLGCTIHEMCMY
|........ | ||| ||| |    .  ...  .    |  |||| .  .|. .| | || | .. |.. |
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTY
Kinase GL50803_91451.AA Pkinase_Tyr 42-128 25 1e-06 23.14 Pfam 38-129 (270) Show / Hide 
Range on Protein: 42-128
Range on HMM: 38-129/270
Sequence Identity: 25% (23 aa)

NCSSRSA--TKAMRREIAILRNI-QHCNIVRCYDIQRATEES-RYFISMELCNC-DLHDFIRAFRHKRRRIPEATVLTMIKDIASALAFLHN
. .. ..   ... ||..|.... .| ||||.| .    .|. ...| ||.. . ||.|. |. |. .....  . | |  .||.....|..
EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase GL50803_91451.AA CMGC 257-281 32 3.1e-05 12.15 In-house 489-513 (513) Show / Hide 
Range on Protein: 257-281
Range on HMM: 489-513/513
Sequence Identity: 32% (8 aa)

LVQMLLSINPLDRPSAAELLGHPLL
|.. .| ..| .|..|.. | || .
LLKKMLQYDPDKRITAEQALQHPYF
Ank GL50803_91451.AA Ank 557-580 29 0.000603 18.49 Pfam 1-24 (33) Show / Hide 
Range on Protein: 557-580
Range on HMM: 1-24/33
Sequence Identity: 29% (7 aa)

AGMTALHIAAHNNYYSIIPLLLEK
 |.|.||.|......... .||..
DGFTPLHLACRCGHTEVVKMLLQH
Ank GL50803_91451.AA Ank 598-618 42 0.002505 16.26 Pfam 1-21 (33) Show / Hide 
Range on Protein: 598-618
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

QGLTALHIAAINGYVESVSVL
 | |.||.|...|..| |. |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_91451.AA Ank 630-651 27 0.009213 14.22 Pfam 1-22 (33) Show / Hide 
Range on Protein: 630-651
Range on HMM: 1-22/33
Sequence Identity: 27% (6 aa)

NSQTALMLCAIHNHIECARILI
. .|.|.| ....|.|... |.
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_91451.AA Ank 661-681 33 0.65121 7.55 Pfam 1-21 (33) Show / Hide 
Range on Protein: 661-681
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

NGMTALIHAIDSENIEHVRLL
.|.|.|  |. . ..| |..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_91451.AA Ank 692-713 40 8e-05 21.66 Pfam 1-22 (33) Show / Hide 
Range on Protein: 692-713
Range on HMM: 1-22/33
Sequence Identity: 40% (9 aa)

NGRTPLTYAVAKGNTDIIRVLL
.|.||| .|. .|.|.... ||
DGFTPLHLACRCGHTEVVKMLL