Gene GL50803_92498 (G.lamblia)

GL50803_92498

Species: G.lamblia
Alias: GK270, GL50803_92498
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_92498.AA Protein None 898 None Fasta, JSON
GL50803_92498.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of GL50803_92498.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_92498.AA NEK 4-266 50 5.6e-161 541.1 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-286/286
Sequence Identity: 50% (146 aa)

YKELKVLGKGSFGRAVLAQEKSTGIK-----YVMKVIHIAPLKPREREEAL-TEAKILSKLKHPYIVGYHESFADTR--YLHIVMEYAD-AGDLTDA---
|...|..|.||||.. ... ||.| .     ||.| | .  ....|...|.  |..||..||||.||.|..|| .    .|.|||||..  ||| .    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKRQKMKNSLFPEDQIWDWFVQICMALKHVHDR-----KILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQSTLECART-AIGTPYYLSPELCED
||.|| |. .|.|.||||||.|.|.|||..|||     ||||||.|.|||||  . ||   ..||.|||||.|.|..| ..|.|  .|||||.|||.|..
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY--HNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQN

KPYNNKSDIWSLGCVLYEICTL--QHAFEAQ--NMKGLVVKILRG-QYQPISNT--YSRNLREVLDRMLQKDPNKRPSVNQILKLPFL
||||||||||||||||||.|||   |.|||.  ||..|..|| .| ||.||. .  ||. |.... .|||||| .|||.||||..||.
KPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_92498.AA NEK1 4-266 55 6.8e-158 530.85 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-276/276
Sequence Identity: 55% (153 aa)

YKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALTEAKILSKLKHPYIVGYHESFADTRY--LHIVMEYADAGDLTDAIKRQKMKNSL
| ..|..|.||||.|.|...|. |  ||.| | .   .. ||||.. |..||.|.||| ||.| |||    .  | |||||.|.|||  .|.||| |. |
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDEND-----------RSRKTVKLGDFGIAKILQSTLECARTAIGTPYYLSPELCEDKPYNN
|.|||| .||.|||.||.|.|||||||||.|.|||||   .|.            |  .|||||||||..|..|.| |.| ||||||||||.|. |||||
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KSDIWSLGCVLYEICTLQHAFEAQNMKGLVVKILRGQYQPISNTYSRNLREVLDRMLQKDPNKRPSVNQILKLPFL
||||||||||||| ||| |.|||.|.| || ||..| | ||...||. |.. .  |....|  ||||||||. ||.
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase GL50803_92498.AA NEK8 4-266 41 1.8e-128 368.94 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-278/278
Sequence Identity: 41% (119 aa)

YKELKVLGKGSFGRAVLAQEKSTG--IKYVMKVIHIAPLKPREREEALTEAKILSKLKHPYIVGYHESFADTRYLHIVMEYADAGDLTDAIKRQKMKNSL
|    |.|.|.|| ..|   |. .   . . | |    . ..||  |. |  .||.| || |..| ..| .   | |.||||| | | . | .|. | ..
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNK-LF

FPED----------------QIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQSTLECA--RTAIGTPYYLSPELC
..|                 .| . |.|.| |. |.|.  ||||||||||||.     .|.|  ||.|||||.||. .    .  .| .|||||.|||.|
EEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFM-----TRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMC

EDKPYNNKSDIWSLGCVLYEICTLQHAFEAQNMKGLVVKILRG-QYQPISNTYSRNLREVLDRMLQKDPNKRPSVNQILKLPFL
| ||||.|||.|.||||||| |.|  |||| |   ||.|| ..  | |||  ||  .| .    ||.|| .|||. ||.. | .
EGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase GL50803_92498.AA NEK4 4-266 46 5.4e-111 375.05 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-257/257
Sequence Identity: 46% (123 aa)

YKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALTEAKILSKLKHPYIVGYHESFA--DTRYLHIVMEYADAGDLTDAIKRQKMKNSL
|  .|| ||||.|   | ...  . .|||| .       ||| .|. ||..||.|||| || | ||.   . ..| ||| . . |||    |.|  || .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQ--KNQF

FPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQSTLECARTAIGTPYYLSPELCEDKPYNNKSDIWSLGCVL
 .| |. .||||| |||   |...||||||||||||| |  |      .|.|||||...|.   . |.| ||||||.|||.   .||. ||||||||| .
LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFL-TKKN-----IIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCV

YEICTLQHAFEAQNMKGLVVKILRGQYQPISNTYSRNLREVLDRMLQKDPNKRPSVNQILKLPFL
||. || |||.| .|  |. .|. ||  |..  || .| . .  ||.| |.||||. .|.. |..
YEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase GL50803_92498.AA S_TKc 4-266 33 1e-95 325.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

YKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALTEAKILSKLKHPYIVGYHESFADTRYLHIVMEYADA--GDLTDAIKRQKM--KN
|. |...|||.||.  ....|.|| .. .|.|.         | .. | .||.| .||.|| ....| |  .|..||||.|   ||| | ||...   ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

SLFPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQSTLECARTAIGTPYYLSPELCEDKPYNN-KSDIWSLG
. ||| ... .. ||| ||.. |...|.||||| .||.|..        ..|..|||.|..|       .| .|||.|..||..   .|.  |.|.||.|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

CVLYEICTLQHAFEAQNMKGLVVKILRGQYQPISNTYSRNLREVLDRMLQKDPNKRPSVNQILK-------LPFL
|.||| .. .  |.  .|. .  ||.           |. ... ....|||||.|||.. ..|.        |..
CILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_92498.AA NEK-Unclassified 54-266 42 7.2e-88 290.98 In-house 46-258 (258) Show / Hide 
Range on Protein: 54-266
Range on HMM: 46-258/258
Sequence Identity: 42% (94 aa)

ILSKLKHPYIVGYHESFADTRYLHIVMEYADAGDLTDAIKRQKMKNSLFPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLG
|||.|.|| || ||.|| .   |    .| | |.|   |...  ||  | |  |  |..|. ||.  .| |||.|||||.|||||  |       || .|
ILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFDEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDD------TVSMG

DFGIAKILQSTLECARTAIGTPYYLSPELCEDKPYNNKSDIWSLGCVLYEICTLQHAFEAQNMKGLVVKILRGQY------QPISNTYSRNLREVLDRML
||||..|.  | . ||| .||. ..||| |.|.||||.||.|||||..||.||   .| ..||  .  || ..         |.| |||  | .|.  ||
DFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEPFFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFML

QKDPNKRPSVNQILKLPFL
......|||   |. ... 
RRNFQQRPSATEIVEQDYI
Kinase GL50803_92498.AA Pkinase 4-266 27 2e-82 284.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

YKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALT--EAKILSKLKHPYIVGYHESFADTRYLHIVMEYADAG----DLTDAIK-RQK
|. ....|.||||.  ....|.||.....|.|     |. ......   |..|. .|.||.|| ....| | .....||||.. |    || | |. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

MKNSLFPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKIL-QSTLECARTAIGTPYYLSPELCE-DKPYNNKSDI
 . . |.|... ... ||. .|.. |...|.||||| .||..  . .  .  .||..|||.|| .     . . |  |||.|..||..  ...|  |.|.
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCVLYEICTLQHAFEAQ------NMKGLVVKILRGQYQPISNTYS--------------------RNLREVLDRMLQKDPNKRPSVNQILKLPFL
||.||.||| .. .  |  .      ... ....|.....   . . .                    ..........|.|||.|||.  |||. |..
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_92498.AA NEK2 4-266 35 1.3e-80 271.18 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-319/319
Sequence Identity: 35% (113 aa)

YKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALTEAKILSKLKHPYIVGYHESFAD--TRYLHIVMEYADAGDLTDAIKRQKMKNSL
|  |...|.|||||      ||.|   | | |    .   |.     |  ||..||||.|| |     |  .  | |||||   |||   ||. .     
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

FPEDQIWDWFVQICMALKHVHD---------------------RKILHRDLKTQNIFLCTDEN---------------------------------DRSR
..|  ||  . |.| ||. .|                      . |||||.|  ||||  |.|                                 | |.
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

KTVKLGDFGIAKILQSTLECARTAIGTPYYLSPELCEDKPYNNKSDIWSLGCVLYEICTLQHAFEAQNMKGLVVKILRGQYQPISNTYSRNLREVLDRML
  ||||||| |..|.     | | .||||| |||. .. .|| ||||||.||..|| |.|   |.| | . | .||  | ...|   ||| | |.  .|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

QKDPNKRPSVNQILKLPFL
  |. .|||.. ||. |..
NVDHYHRPSIEEILQHPQI
Kinase GL50803_92498.AA CAMK 9-266 22 8.6e-73 233.68 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-425/425
Sequence Identity: 22% (94 aa)

VLGKGSFGRAVLAQEKSTG------------IKYVMKVIHIAPLK--------------------------PREREEALTEAKILSK-------LKHPYI
.||.||||   |...|.|.             |. .|.|    ||                          |. |.. . | .|..|       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGYHESFADTRY-------------------LHIVM---EYADAG----DLTDAIKRQ------------KMKNSLFPEDQIWDWFVQICMALKHVHDRK
.  .| . |..|                   ...||   ||.. |    || | |...              ..  |.|..   .| ||| |... |...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

ILHRDLKTQNIFLCTDENDR-----------SRKTVKLGDFGIAKILQSTLEC-----------------------ARTAIGTPYYLS-PELCED-----
| |||||  || |.....|.           .. ..|. ||| |.....  ..                        .|  |||.| . ||. .      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYNNKSDIWSLGCVLYEICTLQHAFEAQ-------------NMKGLVVKILRGQYQ-P------------------ISNT----YSRNLR
         ..|. |.|.||.|..||   .    |..              |.. |  ||..|.|. |                  ||.      |   .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

EVLDRMLQKDPNKRPSVNQILKLPFL
  . .|||.||.||... |.|. |..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_92498.AA STE 4-266 25 2.4e-72 246.64 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-359/359
Sequence Identity: 25% (94 aa)

YKELKVLGKGSFGRAVLAQEK------STGIK---------YVMKVIHIAPLKP---------------REREEALTEAKILSKLK--HPYIVGYHESFA
.. ....|||.||  ..|  .      .|| .         . .|.... . ..                |... | | ||..|..  ||.|| |. .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DTR-------YLHIVMEYADAGDLTDAIK-RQKMKNSL---------FPEDQIWDWFVQICMA-LKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLG
.         .|.|.||| |.| |.| || . .....|         |||.||    .||. . |.. |. .| |||.| .||.|           ||| 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----------VKLC

DFGIAKILQS---------------TLE-CARTAIGTPYYLSPELCE------DKPYNNKSDIWSLGCVLYEICTLQHAFEA-QNMKGLVVKILR-----
|||....|..               |      | .||| . .||  .      ||.|. |.|||||||.. | .| .. .   ..|. .  ..       
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

---------GQYQPISN-------------------TYSRNLREVLDRMLQKDPNKRPSVNQILK--LPFL
         |.  |. .                    .| .... ... |||||||||...| ||   ||.
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_92498.AA NEK11 4-266 40 7.7e-70 238.34 In-house 1-259 (259) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-259/259
Sequence Identity: 40% (107 aa)

YKELKVLGKGSFGRAVLAQEKST----GIKYVMKVIHIAPLKPREREEALTEAKILSKLKHPYIVGYHESFADTRYLHIVMEYADAGDLTDAIKRQKMKN
|   . || ||||   |  .|       .| |.| | .  | | |   |  ||..||.|.|| || .| || .     |. || .  || . |.  |   
YVLQQKLGSGSFGTVYLVSDKKAKRGEELK-VLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFCIITEYCEGRDLDYRIQEYKQAG

SLFPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQSTLECARTAIGTPYYLSPELCEDKPYNNKSDIWSLGC
 .||| || .||.|. .    .|.|.||||||| .||||           .|.||||....|    . | |  ||| |.|||    . |  ||||||| |
KIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNN-------LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLAC

VLYEICTLQHAFEAQNMKGLVVKILRGQYQPISNTYSRNLREVLDRMLQKDPNKRPSVNQILKLPFL
.|||.| ..|||   |   .|..|  |.   . . | | |  ...||| |.|  |||  .||| |..
ILYEMCCMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase GL50803_92498.AA Ciliate-E2 4-266 22 3.1e-64 219.42 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YKELKVLGKGSFGRAVLAQEKSTGIK-----------------------YVMKVIHIAPLKPREREEA-L----------TEAKILSKLKHPYIVGYHES
|| .|..|.|.||   ... .... .                       | ||...   ..  ..|.  .           | .||..|.||.|. ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FA--DTRYLHIVMEYADAGDLTDAIKRQ-KMKNSLFP------EDQIWDWFVQIC---------------MALKHVHDRK-ILHRDLKTQNIFLCTDEND
|   |. .. .||||.. ||| | || . | .|. ..      | .| . . ||.                ||.. | .. |.|||.| .||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

RSRKTVKLGDFGIAKILQSTLE-------------------------------CARTAIGTPYYLSPELCEDKP---------YNNKSDIWSLGCVLYEI
     .|. |||..|...   .                                ..| .|||.|..||  . |.         |. |.||||||..||| 
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

CTLQHAFEAQNMKGLVVKILRGQYQ-P----------------ISNTYSRNLREVLDR----MLQKDPNKRPS-VNQILKLPFL
.. .. |          .|. .... |                . .  | .    . .    ||||||.||..  .|||. |..
LFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_92498.AA TyrKc 4-266 21 3.4e-18 67.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YKELKVLGKGSFGRAVLAQEKSTGIKYVMKVIHIAPLKPREREEALTEAKILSKL--KHPYIVGYHESFADT-------RYLHIVMEYADAGDLTDAIKR
 . .|.|| | ||. .... |   |.   |...        ||. . ||.|..||  .|| ||  .    .          | |||||.. ||| | ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QKMKNSLFPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQST--------LECARTAIGTP-----YYLSPE
 . |   .. ..  .. .||.    . |.... |||| . |. .  .       ||| .||| .. . .            ...  |.        ..||
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

LCEDKPYNNKSDIWSLGCVLYEICTLQHAFEAQ------NMKGLVVKILRGQYQPISNT--------YSRNLREVLDRMLQKDPNKRPSVNQILKLPFL
   .. .. |||.|| | ...||.|.             . . .. .. .| . |.            .  . ..  .  . ||..||. ..|    ..
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_92498.AA Pkinase_Tyr 4-164 25 6.3e-17 57.94 Pfam 1-164 (270) Show / Hide 
Range on Protein: 4-164
Range on HMM: 1-164/270
Sequence Identity: 25% (43 aa)

YKELKVLGKGSFGRAVLAQEK----STGIKYVMKVIHIAPLKPRE--REEALTEAKILSKL-KHPYIVGYHESFA-DTRY--LHIVMEYADAGDLTDAIK
 . .|.||.|.||. ...  |    .|.|.   |..      ...  ||. . ||||...| .|| || ..     . .   . |||||.  ||| |  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RQKMKNSLFPEDQIWDWFVQICMALKHVHDRKILHRDLKTQNIFLCTDENDRSRKTVKLGDFGIAKILQST
.... .  ..  .. .. .||.... . ..... |||| . |. .         ..|| .||| |. ....
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE------NNVVKICDFGLARDIYND
Kinase GL50803_92498.AA Pkinase_Tyr 178-207 36 0.000658 13.86 Pfam 181-210 (270) Show / Hide 
Range on Protein: 178-207
Range on HMM: 181-210/270
Sequence Identity: 36% (11 aa)

LSPELCEDKPYNNKSDIWSLGCVLYEICTL
..||   .. .. |||.|| | ...||.|.
MAPECINYGKFTTKSDVWSFGVLMWEIFTY