GL50803_95557

Species: G.lamblia
Alias: GL50803_95557, GK281
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_95557.AA Protein None 801 None Fasta, JSON
GL50803_95557.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of GL50803_95557.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_95557.AA WEE 320-365 29 1.1e-08 25.35 In-house 251-297 (297) Show / Hide
Range on Protein: 320-365
Range on HMM: 251-297/297
Sequence Identity: 29% (14 aa)

SLDKEYYT-KGLDKEYGADLAILLRSMMQTNYRKRPTLSYILNLPLL
|.||..     .| .....|  |...||. ....||| . .|. |.|
SFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL

Kinase GL50803_95557.AA NEK 334-365 34 6e-06 17.5 In-house 255-286 (286) Show / Hide
Range on Protein: 334-365
Range on HMM: 255-286/286
Sequence Identity: 34% (11 aa)

YGADLAILLRSMMQTNYRKRPTLSYILNLPLL
|  ||  |...| | .  .||. . ||..|..
YSQDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase GL50803_95557.AA NEK8 330-365 25 3.4e-05 10.63 In-house 243-278 (278) Show / Hide
Range on Protein: 330-365
Range on HMM: 243-278/278
Sequence Identity: 25% (9 aa)

LDKEYGADLAILLRSMMQTNYRKRPTLSYILNLPLL
..  | ...  | ..  |.   .||..| |.  ||.
ISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC

Kinase GL50803_95557.AA CAMKL 337-365 44 4.3e-05 12.03 In-house 269-297 (297) Show / Hide
Range on Protein: 337-365
Range on HMM: 269-297/297
Sequence Identity: 44% (13 aa)

DLAILLRSMMQTNYRKRPTLSYILNLPLL
|.  |.|.|.|.|  ||||.  |.| | .
DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

S_TKc GL50803_95557.AA S_TKc 16-365 12 0.000205 -112.18 SMART 1-231 (231) Show / Hide
Range on Protein: 16-365
Range on HMM: 1-231/231
Sequence Identity: 12% (46 aa)

WEETTMVRQCTNSRVLCCYKLEDNE------VDDDEKAHLKTRLDLLLTVRHQ---GMRLIYEPTSPPYLFYAYCGG--GSLQDAFKSHILQETK--FSR
.|    . . . ..| .|.. ....      ..     |..  ...|   .|     .  ...  .  |..  ||.|  |.| |  |..  . ..  |. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

DEILDMLYQLASLCIFLYESQTGIL-----DENSIIIDPRCIFYDDYGMLRVEFGCPMFKMVHVKKKFTSTADAGDVVMMTSLPLPDLFYDMSGAIDPES
 ..  ..||...   .. .   ||.      || | .|  .|   | |. |.                                                
-HARFYMYQICCALEYCHSH--GIIHRDLKPEN-ILLDE-HIKICDFGLARQL-----------------------------------------------

MMGANIFNRRDNFSDIASDTSASVSEVAMADSSTNAITNSEHNSSVQSNTQSNAKASKYLHDPLTPYRRQPLNTDICHHDRYVPPEYYNQQQDTP-EGVV
                                                                         | .|    |..||     . .. .  .
-------------------------------------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDW

WSIGRLLYDACQLTGSIHKTALSSLDKEYYTKGLDKEYGADLAILLRSMMQTNYRKRPTLSYILN-------LPLL
||.| .||  .      .       ... . | .      ..  ..| ..| . .||||   .|.        | .
WSCGCILYEMLCGYPPFP------QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_95557.AA NEK-Unclassified 332-365 29 0.000218 10.1 In-house 225-258 (258) Show / Hide
Range on Protein: 332-365
Range on HMM: 225-258/258
Sequence Identity: 29% (10 aa)

KEYGADLAILLRSMMQTNYRKRPTLSYILNLPLL
| | .||  ..| |.. |. .||    |. ..  
KTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI

Kinase GL50803_95557.AA CAMK 341-365 40 0.000434 8.28 In-house 401-425 (425) Show / Hide
Range on Protein: 341-365
Range on HMM: 401-425/425
Sequence Identity: 40% (10 aa)

LLRSMMQTNYRKRPTLSYILNLPLL
|.|.|.|..  ||.|.. .|| | .
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase GL50803_95557.AA NEK 80-114 29 0.002386 8.11 In-house 87-125 (286) Show / Hide
Range on Protein: 80-114
Range on HMM: 87-125/286
Sequence Identity: 29% (12 aa)

YCG-GGSLQDAFKSHILQETK-----FSRDEILDMLYQLAS
||  || |.. .||  ... |     |. ..|.|...|...
YCEGGGDLYQKIKS--IKKQKQKGKYFEEEQIWDWFIQMCL

Kinase GL50803_95557.AA WEE 80-113 25 0.236734 0.38 In-house 86-121 (297) Show / Hide
Range on Protein: 80-113
Range on HMM: 86-121/297
Sequence Identity: 25% (9 aa)

YCGGGS--LQDAFKSHILQETKFSRDEILDMLYQLA
|| |||  ||.......    ... ..| . | ...
YCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDIC

Ank GL50803_95557.AA Ank 383-401 36 10.733027 3.16 Pfam 1-19 (33) Show / Hide
Range on Protein: 383-401
Range on HMM: 1-19/33
Sequence Identity: 36% (7 aa)

DGNTQLMIAAAEGDIASVR
||.| |..|.  |..  |.
DGFTPLHLACRCGHTEVVK

Ank GL50803_95557.AA Ank 413-428 37 0.242086 9.1 Pfam 1-16 (33) Show / Hide
Range on Protein: 413-428
Range on HMM: 1-16/33
Sequence Identity: 37% (6 aa)

RGETALMLALKHGQED
 |.|.|.|| ..|...
DGFTPLHLACRCGHTE

Ank GL50803_95557.AA Ank 507-527 38 0.388278 8.36 Pfam 1-21 (33) Show / Hide
Range on Protein: 507-527
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

PGTTALMMAASVGSTGCVEQL
 | |.|..|.. |.| .|. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_95557.AA Ank 538-564 37 0.003425 15.77 Pfam 1-27 (33) Show / Hide
Range on Protein: 538-564
Range on HMM: 1-27/33
Sequence Identity: 37% (10 aa)

KGMTAMMHAVLRGQTDVVCFLSQYEAN
 |.|. . |...|.|.|| .| |. |.
DGFTPLHLACRCGHTEVVKMLLQHGAD

Ank GL50803_95557.AA Ank 628-651 33 0.003866 15.58 Pfam 1-24 (33) Show / Hide
Range on Protein: 628-651
Range on HMM: 1-24/33
Sequence Identity: 33% (8 aa)

GGYSALMLAAQYGNIRAVESLLKY
 |...|.||...|... |. ||..
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_95557.AA Ank 659-680 54 0.000284 19.67 Pfam 1-22 (33) Show / Hide
Range on Protein: 659-680
Range on HMM: 1-22/33
Sequence Identity: 54% (12 aa)

DGTTALMLAIRYGYTSVAKVLV
|| |.|.||.|.|.|.|.| |.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_95557.AA Ank 696-716 42 0.009512 14.17 Pfam 1-21 (33) Show / Hide
Range on Protein: 696-716
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DKYTALMEAAVCGDLEIVNAL
| .|.|. |. ||..|.|  |
DGFTPLHLACRCGHTEVVKML