GL50803_96878

Species: G.lamblia
Alias: GL50803_96878, GK307
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_96878.AA Protein None 999 None Fasta, JSON
GL50803_96878.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of GL50803_96878.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_96878.AA AGC 175-261 23 4.1e-11 23.47 In-house 273-374 (395) Show / Hide
Range on Protein: 175-261
Range on HMM: 273-374/395
Sequence Identity: 23% (27 aa)

YAPPELLHAVAKSELQGTLTEKADLWS--LGCLIYEFITGLKPLRVSP----------VMEAYNMSM----TIMETISLP----------PSYDKDIKPV
| .|| |            .  .| ||  ||||.||..||. | .  .           || ..  |    .|.. . .|          .. ... |  
YMAPEIL-----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDL

LSILLSPIPARRL
.. || . |..||
IKKLLCKDPEKRL

S_TKc GL50803_96878.AA S_TKc 7-272 17 1.6e-08 -51.87 SMART 1-231 (231) Show / Hide
Range on Protein: 7-272
Range on HMM: 1-231/231
Sequence Identity: 17% (51 aa)

YEPGALWGQGLDRCLYTVEAKRDKARYICRELSYACLTPTQQERLSARISGARKMVCQHVGQIADVICDEGEQKHYIL--YSAG--QTLAELRALKKP--
|| . . |.|   . | .  |... .. . ...      ...|.   .        . .. .. ||. |   .. |.   |  |   .| ..   ...  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK------HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

-----SLDDVHSSLMQLLKALAYLHSKVKPDSDVGVVLAGI----LTPERILCSKGLLKVVDY----VLPDSLSIGEALLDNQEMYC----YAPPELLHA
     .  .. . . |...||.|.||             ||    | || ||...  .|. |     .|                .|    | .||.|  
LRFPFPE-HARFYMYQICCALEYCHS------------HGIIHRDLKPENILLDE-HIKICDFGLARQL--------------TTFCGTPWYMAPEVL--

VAKSELQGTLTE-KADLWSLGCLIYEFITGLKPLRVSPVMEAYNMSMTIMETISLPPSYDKDIKPVLSILLSPIPARRLPAMALQN-------NPRI
          .  |.| ||.||..||...|  | .   ... ... .            ... |  .. .|   |..|. |  . .        | .
--------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_96878.AA Aur 195-212 50 1.8e-07 15.21 In-house 180-197 (257) Show / Hide
Range on Protein: 195-212
Range on HMM: 180-197/257
Sequence Identity: 50% (9 aa)

EKADLWSLGCLIYEFITG
.| |.|.|| |.||...|
HKVDIWCLGVLCYELCHG

Kinase GL50803_96878.AA PDK1 194-215 45 7.1e-07 16.53 In-house 217-238 (307) Show / Hide
Range on Protein: 194-215
Range on HMM: 217-238/307
Sequence Identity: 45% (10 aa)

TEKADLWSLGCLIYEFITGLKP
|  .|.|.|||.|| ...|. |
TPSCDIWALGCIIYQMVAGQPP

Kinase GL50803_96878.AA GEK 175-239 29 3e-06 16.31 In-house 167-229 (269) Show / Hide
Range on Protein: 175-239
Range on HMM: 167-229/269
Sequence Identity: 29% (19 aa)

YAPPELLHAVAKSELQGTLTEKADLWSLGCLIYEFITGLKPLRVSPVMEAYNMSMTIMETISLPP
|  ||.|.|.     .|   .. | |||| ..||.. |  |     ..| |   |   . ...|.
YISPEILQAMEDG--KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPS

Kinase GL50803_96878.AA Akt 194-213 42 3e-06 15.86 In-house 180-200 (264) Show / Hide
Range on Protein: 194-213
Range on HMM: 180-200/264
Sequence Identity: 42% (9 aa)

TEKADLWS-LGCLIYEFITGL
| ..| |. |||..||...|.
TKAVDWWGSLGCVMYEMMCGR

Kinase GL50803_96878.AA CMGC 194-216 40 4e-06 15.09 In-house 313-342 (513) Show / Hide
Range on Protein: 194-216
Range on HMM: 313-342/513
Sequence Identity: 40% (12 aa)

TEKADLWSLGCLIYEFITG-------LKPL
|.. | ||.|| ..| .||       .|||
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPL

Kinase GL50803_96878.AA Ciliate-E2 194-215 45 5e-06 16.79 In-house 274-295 (365) Show / Hide
Range on Protein: 194-215
Range on HMM: 274-295/365
Sequence Identity: 45% (10 aa)

TEKADLWSLGCLIYEFITGLKP
..|.|.||||...||...|  |
DYKCDIWSLGVILYEMLFGKPP

Kinase GL50803_96878.AA SCY1 192-217 42 8e-06 16.18 In-house 249-274 (337) Show / Hide
Range on Protein: 192-217
Range on HMM: 249-274/337
Sequence Identity: 42% (11 aa)

TLTEKADLWSLGCLIYEFITGLKPLR
..| ..|..||||||.. ..|.||..
KCTWASDMFSLGCLIWWVYNGKKPQI

Kinase GL50803_96878.AA Ciliate-D1 198-216 47 8e-06 20.38 In-house 1-19 (19) Show / Hide
Range on Protein: 198-216
Range on HMM: 1-19/19
Sequence Identity: 47% (9 aa)

DLWSLGCLIYEFITGLKPL
|.||.||..|| ..| .| 
DIWSFGCILYEMLFGQPPF

Kinase GL50803_96878.AA ULK 196-215 55 1.9e-05 15.1 In-house 236-255 (329) Show / Hide
Range on Protein: 196-215
Range on HMM: 236-255/329
Sequence Identity: 55% (11 aa)

KADLWSLGCLIYEFITGLKP
|.|.|||||..|| ..|  |
KCDIWSLGCIFYEMLYGKPP

Kinase GL50803_96878.AA Pkinase 194-212 47 0.001915 13.26 Pfam 190-208 (293) Show / Hide
Range on Protein: 194-212
Range on HMM: 190-208/293
Sequence Identity: 47% (9 aa)

TEKADLWSLGCLIYEFITG
. |.| ||.||..||...|
GPKVDMWSCGCILYEMLCG

Kinase GL50803_96878.AA CMGC 98-122 19 0.019717 2.76 In-house 156-201 (513) Show / Hide
Range on Protein: 98-122
Range on HMM: 156-201/513
Sequence Identity: 19% (9 aa)

KKPSLDDVH-------------SSLM-------QLLKALA--YLHSK
..  |.. |              ..|       |.|..|.  |.||.
RPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSH

Kinase GL50803_96878.AA Aur 111-153 29 0.062202 0.32 In-house 109-145 (257) Show / Hide
Range on Protein: 111-153
Range on HMM: 109-145/257
Sequence Identity: 29% (15 aa)

QLLKALAYLHSK------VKPDSDVGVVLAGILTPERILCS--KGLLKVVD
|.  || |.|||       |              || || .  .| .|. |
QICNALDYCHSKNIIHRDIK--------------PENILLDQCNGNIKICD

Kinase GL50803_96878.AA SCY1 109-124 37 0.071944 2.37 In-house 130-145 (337) Show / Hide
Range on Protein: 109-124
Range on HMM: 130-145/337
Sequence Identity: 37% (6 aa)

LMQLLKALAYLHSKVK
. |.|.|| .||....
IFQILDALSFLHNDCH

Kinase GL50803_96878.AA Ciliate-D1 83-101 26 2.216389 1.12 In-house 1-19 (19) Show / Hide
Range on Protein: 83-101
Range on HMM: 1-19/19
Sequence Identity: 26% (5 aa)

ILYSAGQTLAELRALKKPS
 ..| | .| |.   ..| 
DIWSFGCILYEMLFGQPPF

Kinase GL50803_96878.AA Pkinase 111-122 50 5.127027 1.14 Pfam 116-127 (293) Show / Hide
Range on Protein: 111-122
Range on HMM: 116-127/293
Sequence Identity: 50% (6 aa)

QLLKALAYLHSK
|.|..|.|.||.
QILRGLEYCHSM

Ank GL50803_96878.AA Ank 394-414 42 0.000455 18.93 Pfam 1-21 (33) Show / Hide
Range on Protein: 394-414
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

TGRTALMHAAICGHSAIAKLL
 |.|.|. |..|||  ..|.|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_96878.AA Ank 426-446 33 5.6e-05 22.2 Pfam 1-21 (33) Show / Hide
Range on Protein: 426-446
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

RGWTALMYAACHNNADVCKVL
 |.|.|..|.......|.| |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_96878.AA Ank 457-477 28 0.013599 13.61 Pfam 1-21 (33) Show / Hide
Range on Protein: 457-477
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

NGFTALMIATQQNSIDAIAEL
.|||.|..| . .... . .|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_96878.AA Ank 488-508 33 0.091735 10.62 Pfam 1-21 (33) Show / Hide
Range on Protein: 488-508
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

TGTTALMMAAKIGSKDAVRHL
 | |.|..|.. |... |. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_96878.AA Ank 519-544 23 0.012279 13.77 Pfam 1-26 (33) Show / Hide
Range on Protein: 519-544
Range on HMM: 1-26/33
Sequence Identity: 23% (6 aa)

NGYAAIHIAAEENKADVLSFLIKREA
.|. . |.|.. . ..|...|... |
DGFTPLHLACRCGHTEVVKMLLQHGA

Ank GL50803_96878.AA Ank 550-572 39 0.000759 18.13 Pfam 1-23 (33) Show / Hide
Range on Protein: 550-572
Range on HMM: 1-23/33
Sequence Identity: 39% (9 aa)

GGLTALHVAALNDSTDSIRYLLQ
 | |.||.|.....|. ...|||
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_96878.AA Ank 612-633 40 0.000192 20.28 Pfam 1-22 (33) Show / Hide
Range on Protein: 612-633
Range on HMM: 1-22/33
Sequence Identity: 40% (9 aa)

DGCTALMHAAQKNSFGVVRDLL
||.|.|. |.....  ||..||
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_96878.AA Ank 581-611 24 0.002489 16.27 Pfam 1-33 (33) Show / Hide
Range on Protein: 581-611
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

RGYTALMLAAMADLPDAVELLVK--EEARMRDN
 |.|.|.||.. . .. |..|..   .  ..|.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_96878.AA Ank 643-663 42 0.000857 17.94 Pfam 1-21 (33) Show / Hide
Range on Protein: 643-663
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

TGSTALHHAVRCNSKDCVRIL
 | |.|| |.||.....|. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_96878.AA Ank 747-776 23 0.061749 11.24 Pfam 1-30 (33) Show / Hide
Range on Protein: 747-776
Range on HMM: 1-30/33
Sequence Identity: 23% (7 aa)

TGYTALAYAAVLNYADLAALLIEKEAGLQA
 |.|.| .|.  .... . .|... | . |
DGFTPLHLACRCGHTEVVKMLLQHGADVNA

Ank GL50803_96878.AA Ank 788-811 58 9.4e-07 28.62 Pfam 1-24 (33) Show / Hide
Range on Protein: 788-811
Range on HMM: 1-24/33
Sequence Identity: 58% (14 aa)

EGSTALMLAAWHGHIEVVRLLLQH
.| |.|.||. .||.|||..||||
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_96878.AA Ank 819-840 50 6e-06 25.84 Pfam 1-22 (33) Show / Hide
Range on Protein: 819-840
Range on HMM: 1-22/33
Sequence Identity: 50% (11 aa)

DGRTALMLASVKGHEEIVSLLI
||.|.|.||. .||.|.|..|.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_96878.AA Ank 850-871 36 0.012201 13.78 Pfam 1-22 (33) Show / Hide
Range on Protein: 850-871
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

RRYTALALAAQRGNLAVIKLLV
  .|.| ||...|.. |.|.|.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_96878.AA Ank 881-901 42 0.185149 9.52 Pfam 1-21 (33) Show / Hide
Range on Protein: 881-901
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

RGFSALMFAVQEGHTKSVGYL
 ||..|. |.. |||. | .|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_96878.AA Ank 912-933 31 0.00661 14.74 Pfam 1-22 (33) Show / Hide
Range on Protein: 912-933
Range on HMM: 1-22/33
Sequence Identity: 31% (7 aa)

NGQTALMSAASHGFIKCLSILL
.|.|.|. |...| ..... ||
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_96878.AA Ank 943-973 27 2.5e-05 23.45 Pfam 1-33 (33) Show / Hide
Range on Protein: 943-973
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

DGYTALMSACKHAHAEAITLLVD--HELGLRTK
||.|.|. ||.. |.| ...|..   .. ....
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD