Gene CG9374 (Fruit Fly)

CG9374

Species: Fruit Fly
Alias: STK11, CG9374, LKB1/PEUTZ JEGHERS KINASE, SFO045, anon-EST:Posey135
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 87F7--9,

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
CG9374.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
CG9374.AA Protein Various 540 None Fasta, JSON

Protein domain

Protein domains of CG9374.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG9374.AA LKB 145-408 70 5.9e-243 728.87 In-house 1-265 (265) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-265/265
Sequence Identity: 70% (188 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGG-LQEMIDYQPDKR
|.|||||||||||||||.|.|..|||.||||..|.||||||||.|||..||..||...||||..|.||.|||||||||.||||||.| .|||.|.||.||
YMMGDVLGEGSYGKVKECMDSYTLCRRAVKIMKKKKLRRIPNGWQNVKKEIQILKRMHHRHVIQLIDVFYNEEKQKMYMVMEYCVCGTMQEMLDMQPCKR

MPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANG-HETFAGFKVDIWSSGVTLY
||..|||.||.||.||.|||||.||.|||||||||||..|.||||.||||||||..|..||.|||.||||||||||.||| |.||.||||||||.|||||
MPIWQAHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRDDCCTTSQGSPAFQPPECANGNHDTFSGFKVDIWSMGVTLY

NLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWF
|..||.|||||||.|.|.||||..|||.|.| |..|.|..||| ||||.|..||.|...|.|..||
NMTTGKYPFEGDNMYKLFENIGKCQWEMPCW-YDCDKDLQNLIKGMLQYDHNKRFSCHQIMHHPWF
Kinase CG9374.AA CAMKL 145-408 34 3.5e-123 394.99 In-house 1-297 (297) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-297/297
Sequence Identity: 34% (102 aa)

YIMGDVLGEGSYGKVKEAMN-SENLCRLAVKILTKRKLRRIPNGEQN-----------VTREIALLKQLK---HRHVVELVDVLYNEEK----QKMYLVM
|..|..||.||.|||| |.. . . .. |.||. |.|.. .|. ..|           ..|||...|.|.   | ... | .|....|.    .|.||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCVGG---LQEMIDYQPDKR--MPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQ--TLKISDFGVAEQLD-L-FAPDDTCTTGQGSPAFQ
||| ||   |...|. ....|  ||  .|. ||.|.|....|.||....| |||| |.||. ..  ..||.||| . . .   | |.....|  |||...
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEIANG-HETFAGFKVDIWSSGVTLYNLATGQYPFEGDNI-------YRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWF
.||| .| .. . |.|||||| ||.||.. .|..||..|..       . .|... ... . |   |... |  .|| .||| .|.|| ....|. . |.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase CG9374.AA CAMK 150-408 22 1.3e-97 315.07 In-house 1-425 (425) Show / Hide 
Range on Protein: 150-408
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

VLGEGSYGKVKEAMNSENL------------CRLAVKILTKRKLRR------------------------IPNGEQNVTREIALLKQ-------LKHRHV
.||.||.||||.... ..              . |.||. |.||.                          |. ..|| |||...|.       |.|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VELVDVLYNEE-----------------KQKMYLVM---EYCVGG-----LQEMIDYQPD-------------KRMPLFQAHGYFKQLVDGLEYLHSCRV
. | .|  ...                 ...||.||   ||| ||     | ..|  ...             .|..  .|. ||.|......|.||. .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHKDIKPGNLLLSLDQ-----------------TLKISDFGVAEQL---------------------DLFAPDDTCTTGQGSPAFQP-PEIANGH-----
.| |.|| |.||. .                  ..||.||| | ..                     . ..... ..|  |.|.. . ||. ||      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------ETFAGFKVDIWSSGVTLYNLATGQYPFEGD-------------NIYRLLENIGRGQWE-APAWLYE--------------------MDADFAN
       ..  |.|.|.|| || || . .| .||.||             |.|.|.|.| .|...  | .. .                     ...  .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LILGMLQADPSKRLSLQEIRHDTWF
|| .||| ||.||......  . |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CG9374.AA S_TKc 145-408 29 1.4e-80 274.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-231/231
Sequence Identity: 29% (81 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVG---GLQEMIDYQPD
| .....|.|..|||. . . .   . |.||.            ... |||..||. .| ..| | || ..   ...|.||||| |    | ..|. .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

KR----MPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIWSS
..    .|  .|  |..|....|||.|| ..|| |.|| |.||.   ..||.|||.| ||         ||  |.| . .||.      . ..|.|.|| 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRH-------DTWF
|..|| ...|. ||.  ........||             . .. ..| ..|| ||.||..  |. .       . ||
GCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG9374.AA Pkinase 145-408 28 4.5e-75 260.53 Pfam 1-293 (293) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTR--EIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQ---
|  | ..|.||.|.|.....  . .. ||||. ||  .. .. .|. .|  ||...| |.| ..|.| |. ..  |...|.||||| |||   .|     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYI

---PDKRM--PLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTL----KISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGF
    ....  .  ..  |..|.. ||||.||...|| |.|| |.|.. . ..    ||.|||.|.|.|   ..  .||  |.| . .||. . . .  | 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

KVDIWSSGVTLYNLATGQYPFEGD------NIYRLLENIGRGQWEAPAWLY------------------EMDADFANLILGMLQADPSKRLSLQEIRHDT
|||.|| |..|| ...|. || |.      . . ....|...... . .                    ... ..  .| ..|. ||.||.. ..| .. 
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WF
||
WF
Kinase CG9374.AA CAMKK 145-408 23 2.1e-72 228.97 In-house 1-396 (396) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-396/396
Sequence Identity: 23% (94 aa)

YIMGDVLGEGSYGKVKEAMNSEN-LCRLAVKILTK----RKLRR----------------------IPNGEQNVTREIALLKQLKHRHVVELVDVLYNEE
|  ....|.|..|||| | |...     |.||..|     || .                      ..|....| .||| .| . | ..| |. |. ...
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

KQKMYLV-MEYCVGG-LQEMIDYQP-----------------------DKRMPLFQ---------------------AHGYFKQLVDGLEYLH-SCR---
 .| |.| |||| .| ...  .  .                       .. |   |                     |  || . . |||||| .     
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------VIHKDIKPGNLLLSLDQ---TLKISDFGVAEQLDLFAPDDTCTT-----------GQGSPAFQPPEIANG-HET----------
                .||.|||| |.|.. .    ..||.||||. ...    |.|               .| |||..||      ..          
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFE--GQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRF

---FAGFKVDIWSSGVTLYNLATGQYPFEGDNIYRLLE---NIGRGQWEAPAW--------LY--EMDADFANLILGMLQADPSKRLSLQEIRHDTWF
   . |...|||. ||||| . .|. || ..|.  |..    |     . |           |  |. .|. .||..||. .| ||.....|  ..|.
RFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase CG9374.AA AMPK 145-408 36 5.7e-65 191.85 In-house 1-254 (254) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-254/254
Sequence Identity: 36% (96 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDK-R
||.|. .|||..|||| .         |.||| |.|..     |  . ||| .|| ..| |.. | .|.  | .. ...||||  ||  |  ||   . |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVER-IQREIHILKLFRHPHIIQLYEVII-ETPTDIFMVMEYVSGG--ELFDYIVKHGR

MPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIWSSGVTLYN
..  .|  .|.| . |.||.|   . | | || ||||  .. .|| |||      .    ..  |  |||    ||.  |    .| .|||||.|| || 
LQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSN---MMKDGEFLKTACGSPCYAAPEMISGKL-YCGPEVDIWSCGVILYA

LATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWF
.  |  ||. .|.  |  .|  |. . |..| .   . ..|| .||| || ||.. ..|| . ||
MLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSP---EAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase CG9374.AA Ciliate-E2 145-408 23 1.8e-59 202.83 In-house 1-365 (365) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YIMGDVLGEGSYGKVKEAMNSENLCR-----------------------LAVKILTKRKLRRIPNGEQNVTREIA----------LLKQLKHRHVVELVD
|.   ..|.|..|.|... . .. ..                        |.||. |.... | . |... |||           .|.||.| .......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQ-EIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VLYNEEKQKMYLVMEYCVGG-LQEMIDYQPDKR---------MPLFQAHGYFKQLVD---------------GLEYLHSCR-VIHKDIKPGNLLLSLDQT
. ... ....||||||| || |.. |  .. ||         . ....  ..||...               .||||||   .|| |||| |.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKISDFGVAEQLDLFAP---------------DDTCTTG--------------QGSPAFQPPEIANG-------HETFAGFKVDIWSSGVTLYNLATGQY
.||.||| . ..| .                 |.. |.|               |.| ...||| ||        ..  ..|.|||| ||.|| . .|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFEGDNIYRLLENIGRGQWEAP----------------AWLYEMDADFANLILG----MLQADPSKRLS-LQEIRHDTWF
||        ...|  .... |                 |..  . .  .||      ||| ||.||..  ..|    ||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKK-WSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CG9374.AA MARK 145-408 35 5.8e-58 188.13 In-house 1-262 (262) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-262/262
Sequence Identity: 35% (95 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQK-MYLVMEYCVGG-LQEMIDYQPDK
| |. ..|.|||.||| | .     . |.||. | || . |.  .|| |||...|.|.| ....| .|   ...|.  ||.|||. || | . |  .|. 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLND-PQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

RMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQ--TLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIWSSGVT
|..   |. .|.|.| ...|.|| ...| |||| |.|.  .     ||.||| . .   . |.   .|  |.|.. .||| .. .   |.|||||| || 
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSIC---IPPGQKLNTFCGTPPYMAPEIFLKKPYD-GPKVDIWSLGVV

LYNLATGQYPFEGDN--IYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWF
|| . .|..||.||.  .  | ..| ||. . |     . ..  |||  .|...|..| ...||  . |.
LYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH---VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase CG9374.AA ULK 145-408 27 2.9e-54 186.59 In-house 1-329 (329) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-329/329
Sequence Identity: 27% (91 aa)

YIMGDVLGEGSYGKVKEAMNSEN----LCRLAVKILTKRKLRRIPNG------EQNVTREIALLKQLK--------HRHVVELVDVLYNEEKQKMYLVME
|.. ..||.||.||| .. | ..        |.|.. | |.....|        | ...|| ..|.||        | ..|.| |....      |..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCVGG-LQEMIDYQPD--------KRMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQ------------TLKISDFGVAEQLDLF--APD
|| || |.. |  .          || .  .|  .|||.. |. .||. ..|| |||| | |.. .|            .|||.||| | ..| .    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

DTCTTG-----QGSPAFQPPEIANGH--ETFAG-FKVDIWSSGVTLYNLATGQYP----FEGDN---IYRLLEN-------IGRGQWEAPA--WLYEMDA
...|.       |.| .  |.| .|.  .   . .|.|||| |. .| . .|..|    |. ..   |..|..|       |   . . |     .    
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

DFANLILGMLQADPSKRLSLQEIRHDTWF
.. .|| .||| |...| | .|. .  ||
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CG9374.AA BRSK 145-408 37 3.1e-54 183.19 In-house 1-254 (254) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-254/254
Sequence Identity: 37% (100 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHVVELVDVLYNEEKQKMYLVMEYCVGGLQEMIDYQPDK-R
|...  || |  |.||  .      . |.||  | ||   .   . | ||||..|   | || .. ||   | |  .||..|.  ||  |. ||   | |
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVY--ENKKYLYLILEHVSGG--ELFDYLVKKGR

MPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQGSPAFQPPEIANGHETFAGFKVDIWSSGVTLYN
.    |  .|.| . .|.. ||  . | | || ||||. ..  || ||| |    |   |    |  ||| .  ||.  | | . | | |.|| || || 
LTPKEARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMAS---LQVKDMMLHTSCGSPHYACPEVIRG-EKYDGRKADVWSCGVILYA

LATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILGMLQADPSKRLSLQEIRHDTWF
| .|  ||  ||. .||| . ||    | .     .|  .|  ||.  ||.||.||.||.   |.
LLVGALPFDDDNLRQLLEKVKRGVFHMPHF---IHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase CG9374.AA ULK 145-408 29 9.9e-54 184.82 In-house 1-324 (324) Show / Hide 
Range on Protein: 145-408
Range on HMM: 1-324/324
Sequence Identity: 29% (95 aa)

YIMGDVLGEGSYG-KVKEAMNSEN---LCRLAVKILTKRKLRRIPNG------EQNVTREIALLKQLK------HRHVVELVDVLYNEEKQKMYLVMEYC
|.. ..||.||.| || .. | ..       |.|.  | |.. ..|        |.  .|| ..|.||      | |.|.| |....      |..||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

VGG-LQEMIDYQPD-------KRMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQ------------TLKISDFGVAEQLDLF-APDDTCT
 || |.. |  .         || .  .| ..|||.. |. .||.  .|| |||| |.|.. .|            .|||.||| | ..|     .. |.
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TGQ------GSPAFQPPEIANGH--ETFAG-FKVDIWSSGVTLYNLATGQYP----FEGDN--IYRLLEN-------IGRGQWEAPA--WLYEMDADFAN
|        |.| .  |.| .|.  .   . .|.|||| |. .| . .|.||    |. ..  |..|..|       |   . . |     .    .. .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LILGMLQADPSKRLSLQEIRHDTWF
|| .||| |...| | .|| .  ||
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase CG9374.AA TyrKc 145-407 23 6.9e-17 50.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 145-407
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQL--KHRHVVELVDVLYNEEK-----QKMYLVMEYCVGG-----L
  .|..|||| .|.| ... .      ||| | . .       ..   ||. ....|  .| ..| |. |   ..      . ...||||. .|     |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

QEMIDYQPDKRMPLFQAHGYFKQLVDGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVAEQLDLF-----APDDTCTTG--QG---SPAF-QPPEIA
..  .       .. . . .  |  .| ||||| ..|| |.   | |.. ..| |||||| .  ..       . |   ...  .|    |    .||  
RKHRPK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

NGHETFAGFKVDIWSSGVTLYNLAT-GQYPFEG-----DNIYRLLENIGRG-QWEAPAWLYE-----MDADFANLILGMLQADPSKRLSLQEIRHDTW
| ..    .| |.|| ||... . | || | .|      . ....|.. .|   . |.  |.     . ..  ....   ..||..| . .|| |. .
NYGKF--TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase CG9374.AA Pkinase_Tyr 145-231 28 5.2e-09 31.15 Pfam 1-92 (270) Show / Hide 
Range on Protein: 145-231
Range on HMM: 1-92/270
Sequence Identity: 28% (27 aa)

YIMGDVLGEGSYGKVKEAMNS----ENLCRLAVKILTKRKLRRIPNGE---QNVTREIALLKQL-KHRHVVELVDVLYNEEKQ-KMYLVMEYCVGG
 ..| .||||..|.|...       .. .  |||.| |         .   .   ||....||| .| ..| |. | . .... ..|.||||. .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG
Kinase CG9374.AA Pkinase_Tyr 258-294 43 0.000704 13.76 Pfam 122-158 (270) Show / Hide 
Range on Protein: 258-294
Range on HMM: 122-158/270
Sequence Identity: 43% (16 aa)

DGLEYLHSCRVIHKDIKPGNLLLSLDQTLKISDFGVA
.|.|||.| . || |.   | |.. . . ||.||| |
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA