CG10177

Species: Fruit Fly
Alias: CG10177, MLCK-like, SFO168
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 95A1,

Classification

Group: CAMK
Family: DCAMKL

Sequence

Name Sequence Type Origin Length Description Download
CG10177.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON
CG10177.AA Protein Various 411 None Fasta, JSON

Protein domain

Protein domains of CG10177.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DCX CG10177.AA DCX 17-108 45 5.7e-42 146.67 SMART 1-96 (96) Show / Hide
Range on Protein: 17-108
Range on HMM: 1-96/96
Sequence Identity: 45% (44 aa)

LHKKALRVCFLRNGDRHFKGVNLVISRAH-FKDFPALLQGVTESLKRHVLLRSA--IAHFRRTDG-SHLTSLSCFRET-DIVICCCKNEEIICVKYS
 |.|..|.|| ||||..||||.|||.|.. ||.|..||| ||. .|.||.....  ..|...||| .. |||..|... |...|||.||....|.|.
HHWKPKRICFYRNGDPFFKGVRLVINRKWQFKSFDHLLQDVTQ-TKLHVKMDCPHGVRHIYTTDGRHRVTSLDEFEDGDDFYVCCCTNEKFKPVDYD

DCX CG10177.AA DCX 39-103 35 1.7e-17 64.4 Pfam 1-68 (68) Show / Hide
Range on Protein: 39-103
Range on HMM: 1-68/68
Sequence Identity: 35% (24 aa)

LVISRAHFKDFPALLQGVTESLKRHVLLRSA-IAHFRRTDG-SHLTSLSC-FRETDIVICCCKNEEII
.|..| .||.| |||. .||||...| |... . .  ..||  . ||| . . . ....||| ||...
MVVNRRRFKTFDALLDDITESLHDKVQLPFGAVRKIYTPDGGHRVTSLDEFLQDGGCYVCCCGNERFK

Kinase CG10177.AA CAMK-Unique 149-409 26 1.1e-136 453.79 In-house 1-363 (363) Show / Hide
Range on Protein: 149-409
Range on HMM: 1-363/363
Sequence Identity: 26% (96 aa)

IETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDT------------------YMEAEVLRQLQSHPNIIELMYT----VEDER-------
........|......|....|....|...|||.|||..|.....                  ............|||||.|...    ..|..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------YMYTVLEHLDCN-MQKVIQK--------------------RGILSE--ADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSS-------
        |||.|.|..... ....|||                    .|..||  .|....|.|..||.|.||.....|||.|.||..||.|       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---SGKWNFKMVKVANFDLATYYRGSKLY----VRCGTPCYMAP--------------EMIAMSGYDYQV----DSWSLGVTLFYMLCGKMPFASACKNS
   ...|.....|...|.|...|...| .    ..|||||||||              |.|.|..||.|.    |.|||||...|||||..||...|...
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

------KEIYAAIMSGGP-TYPKDMESV---MSPEATQLIDGLLVSDPSYRVPIAELDKFQFL
      |||...|..|.. .....|...   .|.||..........||..|....||...|..
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase CG10177.AA CAMK 164-409 19 3.4e-80 257.95 In-house 11-425 (425) Show / Hide
Range on Protein: 164-409
Range on HMM: 11-425/425
Sequence Identity: 19% (82 aa)

YRGQTRANR------------TKCTVKMVNKQTQSN---------------------------DRGDTYMEAEVLRQLQ------SHPNIIELMYTVED-
.... . .             .|. .|...|.  ..                           ||   . | |....||      .||||| |  . || 
KLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDP

------------------ERYMYTVL---EHLDCN------MQKVIQK--------------RGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENL
                  ...|| |.   |. .         ......              || ..|..|| ..|  .||....|.. ..|||.||||.
HYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENI

LVCSSSGK-----------WNFKMVKVANFDLATYYRGSK-------------------------LYVRCGTPCYMA-PEMIAM--------------SG
|......            ||   .|.. | .|.......                         .. .||||.||| ||..                 .
LLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPY

YDYQVDSWSLGVTLFYMLCGKMPFASACK-----------NSKEIYAAIMSGGPTYPKDMESV--------------------MSPEATQLIDGLLVSDP
|....| ||.|| |. ||||..|| . |            | .|..  ||.|  ..| .. |                      |.|. .|| ..|. ||
YGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDP

SYRVPIAELDKFQFL
. |  |..  . ...
EKRMTIEQCLNHPWM

Kinase CG10177.AA S_TKc 149-409 25 4.8e-63 216.67 SMART 1-231 (231) Show / Hide
Range on Protein: 149-409
Range on HMM: 1-231/231
Sequence Identity: 25% (72 aa)

IETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDC---NMQKVIQKRGI----
 | .... . .    |... .    .. .|...         ... | ..|..   ||||. | .. .|  ..| |.|..|    .. ..|.|||     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLYVRCGTPCYMAPEMIAMSGYDY-QVDSWSLGVT
  ..| .||..|. ...||...|....||||.||||.|...         .|.. | ||. .     .  |||| |||||..   ||..  .| ||.|..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAELDK-------FQFL
|. ||||. ||     . ....  |.              |||| ..|...|. ||. |  . |. .        ...
LYEMLCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CG10177.AA CAMKL 168-409 27 1.3e-61 195.36 In-house 21-297 (297) Show / Hide
Range on Protein: 168-409
Range on HMM: 21-297/297
Sequence Identity: 27% (80 aa)

TRANRTKCTVKMVNKQTQSNDRGDTYM--------------EAEVLRQLQ--SHPNIIELMYTVEDERY------MYTVLEHLDCN---MQKVIQKR---
.| ...|  .|...|.  .||   . .              |.. ...|.   ||||| |. ..|....      .| |.|. .     ..  |.|.   
IRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHR

-GILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYR------GSKLYVRCGTPCYMAPEMIAM--SGYD-YQ
 | ..| .||   |  |||....|.. ..||||||||.|. ..        .|.. | ....||      | ||  .||.|.|||||...     || ..
RGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPK

VDSWSLGVTLFYMLCGKMPFASAC------KNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAELDKFQFL
|| ||.||.|. |.||..||  ..      .|  . |  ||.|   .|.  .  .| .. .|| ..|. .|..|  | .. .  ..
VDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYH--VS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase CG10177.AA Pkinase 177-409 26 1.1e-55 196.15 Pfam 29-293 (293) Show / Hide
Range on Protein: 177-409
Range on HMM: 29-293/293
Sequence Identity: 26% (71 aa)

VKMVNKQTQSNDRGDTY---MEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDC-----NMQKVIQ--KRGIL--SEADARSVMRCTVSALAHMHQL
|| ..|.... .   |    .|..... | .||||..| ...||....| |.|....         .|.  ..| .  || .....|. ....|...|. 
VKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM

QVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLAT---YYRGSKLYVRCGTPCYMAPEMIA-MSGYDYQVDSWSLGVTLFYMLCGKMPFASAC-----KN
 .||||.||||.|. .        .||.. | ||    | ..| ....|||| ||||| |   ..|.. || ||.|..|..||||. ||   .      .
GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDNHD

SKEIYAAIMSGGPTYPKDMESVMS-----------------PEATQLIDGLLVSDPSYRVPIAELDKFQFL
 ..... ||.. . .. . .. .|                 .|. ..|...|  ||. |  .... .  ..
QMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase CG10177.AA DCAMKL 194-397 35 4.1e-46 141.12 In-house 64-267 (279) Show / Hide
Range on Protein: 194-397
Range on HMM: 64-267/279
Sequence Identity: 35% (74 aa)

MEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDC-NMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKV
.| ....... ||.|| |.  .. |  .| |.|.         | . .  .| ||.  |.|  .|| ..| . ..|||||||||||| .  .   | .| 
NEVSIMQKIK-HPHIIQLYEHWDTETHYYLVMEYVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG--EKSLKL

ANFDLATYYRG--SKLYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLL
. | ||..  |    ||  |||| | ||| ..  ||   || |..|| |  .|||  || |   .  |   .||.| . .|    .  |  |  ||  .|
CDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHML

VSDPSYR
. ||  |
QVDPEKR

Kinase CG10177.AA MSK 177-409 32 6.4e-45 149.78 In-house 29-277 (277) Show / Hide
Range on Protein: 177-409
Range on HMM: 29-277/277
Sequence Identity: 32% (82 aa)

VKMVN-------KQTQSNDRGDTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDCN-MQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIH
.| ..       . |...    |  |. .|. .|.|||| .| |.  |.  .| |.| .  . .   | ||.  .|. .| .||  |.|. ||||. .||
MKILSKATVVQKRKTAEH----TQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIH

RDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGS---KLYVRCGTPCYMAPEMIA----MSG-YDYQVDSWSLGVTLFYMLCGKMPFA----SAC---
||.||||.|  . .       ||.  | .| .   .   ...  |.|  ||||||..      | || ..| |||||.|. || |. ||.    ..    
RDLKPENILFDDEEDN---GHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSC

KNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAELDKFQFL
. ..||   |. | . .| .  . |||.|  || .||  ||. |    .|..   .
NSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK

Kinase CG10177.AA Ciliate-E2 163-409 18 1e-42 144.44 In-house 15-365 (365) Show / Hide
Range on Protein: 163-409
Range on HMM: 15-365/365
Sequence Identity: 18% (70 aa)

IYRGQTRANRT------------------KCTVKMVNKQTQS-NDRGDTYMEAEVLRQLQS---------------HPNIIELMYTVE--DERYMYTVLE
.|... . ..                   |...|.... ... |.   . .|  ..|....               |||||.. .. .  |. ..| |.|
VYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVME

HLDC-NMQKVIQKR-----------GILSEADARSVMRCTVS---------------ALAHMHQLQ-VIHRDIKPENLLVCSSSGKWNFKMVKVANFDLA
 ..  .... |...           . ..|  .. .|.  ..               || ..|.   .|||||||||.|.           .|.. | |.
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----------IKIIDFGLS

TYY------------RGSKLYVR----------------------CGTPCYMAPEMIAMSG---------YDYQVDSWSLGVTLFYMLCGKMPFASACKN
..|            .. ... .                      |||| |||||.. . .         |||..| |||||.|..||.|| ||      
KKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------

SKEIYAAIMSGGPTYPKD--------------MESVMSPEATQLIDG----LLVSDPSYRVP-IAELDKFQFL
    .  |. .   .|.                    |.|. .||      .|. ||. |   . .. . ...
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CG10177.AA RSK 195-409 31 1.1e-42 148.13 In-house 50-278 (278) Show / Hide
Range on Protein: 195-409
Range on HMM: 50-278/278
Sequence Identity: 31% (74 aa)

EAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKRGI---LSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMV
| ..|   |.||.|..| |. ..| . | ..| .    . . .||...   .|| .|. .|.  |.|. |.||...||||.|||| |  . |   |   .
ERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES---NEGHI

KVANFDLATY--YR-GSKLYVRCGTPCYMAPEMIA----MSGYDYQVDSWSLGVTLFYMLCGKMPFAS-ACKNSKEIYAAIMSGG--PTYPKDMESVMSP
|.  |... .   . .....  |.|  ||||||..     .|.| ..| ||||| .. || |. ||.. . .|.||| . |..|   .| | . .  .|.
KLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQY--LSQ

EATQLIDGLLVSDPSYRVP-----IAELDKFQFL
||  || ..|  ||. |       ..|. . ...
EAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase CG10177.AA STE 175-409 19 2.8e-42 146.77 In-house 42-359 (359) Show / Hide
Range on Protein: 175-409
Range on HMM: 42-359/359
Sequence Identity: 19% (65 aa)

CTVKMVNKQTQS----------------NDRGDTYMEAEVLRQLQS-HPNIIELMYTVEDER-------YMYTVLEHLDC-NMQKVIQ-KRGILS-----
. .| .|.....                ... .  .| ........ ||||..   . ..|        . . ..|..|     ..|. | |..      
MAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHN

--------EADARSVMRCTVSA-LAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGS------------------KLYVRCGTPCYM
        |   . . | .. . |.. |....||||||| | |.           || ..| ...    |                  | .  .||| .|
RQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WM

APEMIAM------SGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIM--------------SGGPTYPKDME---------------SVMSPE
|||.|        .|||...| |||| |.  |..|| |..     .   .....               . |. | . .               . .|||
APEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPE

ATQLIDGLLVSDPSYRVPIAELDK--FQFL
  . |.  |. ||. |    .| |    |.
FKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase CG10177.AA Ciliate-E2-Unclassified 163-409 20 3.3e-40 137.17 In-house 15-352 (352) Show / Hide
Range on Protein: 163-409
Range on HMM: 15-352/352
Sequence Identity: 20% (70 aa)

IYRGQTRANR------TKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQ------------------SHPNIIELMYTVEDERYMYTVLEHL-DCNMQKVIQ
.|. | . .       ... ....... . |   .  .|.. . ...                   ||.|. ..|. .|. ..| |.| . . .... |.
VYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIK

KR-----------------GILSEADAR-----SVMRCTVSALAHMHQLQ-VIHRDIKPENLLVCSSSGKWNFKMVKVANFDLAT---------------
||                  |..|  |.       ... ...| ..|. . .|||||||||.|. .. .  |.. .|.. | ..                
KRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYY-IKIIDFGISKKYQQNNNCDTNQQQK

--YYRGSKLYVRCGTPCYM----APEMIAMSGYD----YQVDSWSLGVTLFYMLCGKMPFASACKNS--------------KEIYAAIMSGGPTYPKDME
  ...  ... .||||.||    |||..   .||    |..| ||||| |..|| |. || . ....              |..|  |. . . .||  .
MQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPW

----SVMSPEATQLID----GLLVSDPSYRVPIAELDKFQFL
       ||||  .|      .|. .|..|  . .. . ...
QQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase CG10177.AA MARK 303-409 40 3.3e-31 99.38 In-house 159-262 (262) Show / Hide
Range on Protein: 303-409
Range on HMM: 159-262/262
Sequence Identity: 40% (44 aa)

GSKLYVRCGTPCYMAPEMIAMSGYD-YQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIA
|.||   |||| |||||..    || . || ||||| |..|.||. ||  .... ||.|  | .| ...|      .|.|. .||  ||. .|..|  | 
GQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIE

ELDKFQFL
|. |  ..
EIMKHPWM

Kinase CG10177.AA MARK 195-278 36 1.1e-13 41.28 In-house 49-137 (262) Show / Hide
Range on Protein: 195-278
Range on HMM: 49-137/262
Sequence Identity: 36% (33 aa)

EAEVLRQLQSHPNIIELMYTVE--DERY-MYTVLEHLD-CNMQKVIQKR--GILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLV
|.|....|. |||||.| ...|  .|.   | ..|.    ..   |...  | |.| .||   |  |||.  .|.  ..||||||||.|.
EIEIMKKLD-HPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI

Kinase CG10177.AA TyrKc 156-408 20 3.8e-11 -42.51 SMART 1-280 (280) Show / Hide
Range on Protein: 156-408
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

EHNTRTL-------IYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQL-QSHPNIIELMYTVEDE-------RYMYTVLEHLDC-NMQKVIQKR
 .  ..|       .|.|. .   ... |||... .    | | . ||.....|  .||||. |   . ..         .. |.|. .  . .. ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GI-LSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGS------KLYVRC----GTP--C---YMAPEMIAM
.  |. .|  | .    .  .. |. ..||||.   | || .         ||.. | |. .          | | |     |.        |||| | .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-N

SG-YDYQVDSWSLGVTLFYML-CGKMPFAS-AC--KNSKEIYAAIMSGGPTYPKDM--ESV----MSPEATQLIDGLLVSDPSYRVPIAELDKFQF
 | .  . | || ||... ..  |..|    .   .. .|... ...|.   . .   . .    ...|  |..      ||. |   .|. . .|
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF

Kinase CG10177.AA Pkinase_Tyr 163-271 21 0.000662 13.85 Pfam 19-137 (270) Show / Hide
Range on Protein: 163-271
Range on HMM: 19-137/270
Sequence Identity: 21% (25 aa)

IYRGQTRANRTKCTVKMVNKQTQSND--RGDTYMEAEVLRQLQSHPNIIELMYTVE-DERY--MYTVLEHLDC-NMQKVIQK----RGILSEADARSVMR
...|.   ..... |||.. .. . .  | |   ||....|| .||||. |.  .  ...   .| |.|.  . .. .  .|    .. |.  |  .  .
TWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCW

CTVSALAHMHQLQVIHRDI
   ..... .. . ||||.
QIAKGMEYLESKNCIHRDL

Kinase CG10177.AA Pkinase_Tyr 316-350 32 1.148587 2.88 Pfam 181-217 (270) Show / Hide
Range on Protein: 316-350
Range on HMM: 181-217/270
Sequence Identity: 32% (12 aa)

MAPEMIAMSGYDYQVDSWSLGVTLFYMLC-GKMP-FA
|||| |. . .  . | || ||... ..  |..| ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYP