Gene CG7236 (Fruit Fly)

CG7236

Species: Fruit Fly
Alias: KKIALRE, AC018104, CG7236, SFO090
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 25F3,

Classification

Group: CMGC
Family: CDKL

Sequence

Name Sequence Type Origin Length Description Download
CG7236.AA Protein Various 392 None Fasta, JSON
CG7236.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 286 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of CG7236.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG7236.AA CDKL 4-289 62 3e-212 711.41 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-286/286
Sequence Identity: 62% (181 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLT
||||...||||||||.|||..|||..||.|.|.||||||...|||.|||..||.|||.|.|.|.|||||||.||||||.|. |||||||..|.|..||..
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

KQICYQTLLGVAYCHKQGCLHRDIKPENILLT-AQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALW
.....|.| ....|||. |.||||||||||.| ..||||||||||||||. |||.|||||||||||||||||||||||.|||.|||||..||...|..||
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPLW

PGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF
||.||.||||.|.|.||.|.|||..|| .|..|.|...| ....||||...|.||.  ....||.||||. ||..|..||.|..|.||
PGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSN--KKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase CG7236.AA CMGC 4-289 23 1.2e-123 408.43 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-513/513
Sequence Identity: 23% (122 aa)

YEKLSRLGEGSYGVVYKCRD--------------RETGALVAVKRFVESEDDPAIRK----------IALREIRLLKNLK-----------------HPN
||.....|||.|||||||||              .||. .||.|.. . . ..   |          .|||||..||.|.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVSLLEVFRRKR-----------------RLHLVFEFCELTVLHELERHP---------------------------QGCPEHLTKQICYQTLLGVA--Y
.|.|...|..|                   |.||||... . .. .....                           .  .  . . ..|| | |..  |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

CHKQG--CLHRDIKPENILLTAQ--------------------GQVKLCDFGFARMLSPG----------------------ENYTDYVATRWYRAPELL
||...   .|||.||||||.. .                    |..|.||||.|| ..|                       . ||.||.||||||||.|
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

VGD---------TQYGTPVDVWAIGCLFAELVRG--------EALWPGRSD-----------VDQLYLIRKTLGDLL---------------PR------
.|.         ..|.||.|.|..|| |||...|        . |.||.|.           .|||..| |.||                  ..      
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

-------------------HIQIFGQNEYFKGITLPVPP--TLEPLEDKMP-----------------------------AKSQQNPLTIDFLKKCLDKD
                   |. .|..|  ......| .|  ....|. . |                             ......|. ||.|||.|  |
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PTKRWSCEKLTKHSYF
|.||...|   .| ||
PDKRITAEQALQHPYF
Kinase CG7236.AA Pkinase 4-289 32 2.2e-107 367.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-293/293
Sequence Identity: 32% (99 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALR--EIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELT----VLHELER-HPQ
|......|.||.|.||||... || .||||..  .....  .....|  ||...|.|.||| | |...|..|.....|.|.|| .     |... . . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GC---PEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQV----KLCDFGFARM--LSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAI
||   .|.  | ..||.| |..|||..|..|||.||||||.  .|..    |.||||.|.   . ... .|... |.||.|||.. |.. ||..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCLFAELVRGEALWPGR----SDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKL
||...|.. |. ..||.    . .||...|....|  |.....    . ||. ..    .     .  ..    ...  .||.|.||.|||.||...| .
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI

TKHSYF
 .| .|
LQHPWF
Kinase CG7236.AA S_TKc 4-289 30 1.7e-100 341.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-231/231
Sequence Identity: 30% (91 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCEL---TVLHELERHPQG---
||.|  .|.|..|.|||||...|| .||.|.           . ..|||..||. .|||.| |..||.   .|..|.|.|.    .... ..... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--CPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGT-PVDVWAIGCLFAEL
   ||  .. ..||......|||..| .|||.|||||||.   ..|.||||.|| |      | .. |.||.|||.|    .||. ..|.|..||...|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

VRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTK-------HS
. |. ..|      |.... | .|                                         |  .||..|||.|||.||... .. .       | 
LCGYPPFP------QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

YF
.|
WF
Kinase CG7236.AA CDK 4-218 37 1e-98 316.46 In-house 1-242 (284) Show / Hide 
Range on Protein: 4-218
Range on HMM: 1-242/284
Sequence Identity: 37% (96 aa)

YEKLSRLGEGSYGVVYKCRDRETG-----ALVAVKRF-VESE----DDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRK-----------RRLHLVFEF
|||| ..|||.||||||.||..||      .|| |.. .|.|    ..  .   |.||| |||.| ||| |.|..|.  |           ..| .|||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQ-----VKLCDFGFARMLS-------PGENYTDYVATRWYRAPE
..    . ..           | . .| | |..|||... .|||.|| |||.. .|.     .|. |||.||  .       |   ||  | |.||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLVGDTQYG--TPVDVWAIGCLFAELVR---GEALWPGRSDVDQLYLIRKTLG
|| |...|.  ||.|.|..|| |||...   ...| ||.|. ||| .| ...|
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICG
Kinase CG7236.AA CDC2 4-218 43 6.8e-92 282.67 In-house 1-226 (301) Show / Hide 
Range on Protein: 4-218
Range on HMM: 1-226/301
Sequence Identity: 43% (99 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRF-VESEDDP-AIRKIALREIRLLKNLK-HPNLVSLLEVFRRKRRLHLVFEFCELTVLHELE-RHP--QG
|.|. ..|||.|||||||.|..|. .||.|.. .|.||.   .   |.||| .||.|| |||.|.| .|.   ..| .|||...      ..   |  . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

CPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLS-PGENYT--DYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAEL
 |..| |.. || | ||..|| .. .|||.|| |||. ..|..|. ||| ||  . |  .||    | |.||||||.| |. .| ||||.|.|||.|||.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---VRGEALWPGRSDVDQLYLIRKTLG
   |  ..| .| |  |||. | ..||
FMDVTKKPLFHGDSEIDQLFKIFRILG
Kinase CG7236.AA CDK5 4-218 43 2.1e-77 244.0 In-house 1-217 (287) Show / Hide 
Range on Protein: 4-218
Range on HMM: 1-217/287
Sequence Identity: 43% (94 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLT
|||. ..||| ||.||| |..||. .|| ||    ..|  .   |.||| ||| |||.| | |  |    ..| ||||||       ..    .   |. 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELV-RGEALW
| . || | |.|.||..  |||| || | |   .|. || ||| ||    |  .|.  | | |||.|  | |  .| |..|.| .|| |||..  |  | 
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

PGRSDVDQLYLIRKTLG
|| .. ||| .| | .|
PGNDVEDQLKRIFKIMG
Kinase CG7236.AA MAPK 4-289 32 4.9e-76 258.91 In-house 1-328 (328) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-328/328
Sequence Identity: 32% (106 aa)

YEKLSRLGEGSYGVVYKCRDRETGAL------VAVKRFVESEDDPAIRKIALREIRLLKNL-KHPNLVSLLEVFRRK-----------RRLHLVFEFCEL
|. |...|.|.|||| ...|..|.        ||.|...   ..|   | ..|||.||. . .|.| ..||..|. .           . . .|.|..| 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELME-

TVLHELERHPQ-GCPEHLTKQICYQTLLG--VAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENY---------------TDYVATRWYR
| || . . .|  . .|  . . || | |  . | |  . .|||.||.|||..  ...|.|||| || . | ...               |.||||||||
TDLHQIIKSQQPLSDDHI-QYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYR

APELLVGD--TQYGTPVDVWAIGCLFAELVR-GEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFG-Q---NEYFKGITLPVPPTLEPLEDKMPAKS-QQN
|||.. .   . | . ||.|..|| |||... .  | ||.. .||. || ..||   .  ||  .      .|...  .. ...  |.|.  |  . . |
APEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNAN

PLTIDFLKKCLDKDPTKRWSCEKLTKHSYF
|. ||.|.| |  || ||.. |    | ||
PQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CG7236.AA RCK 47-218 41 1.4e-69 219.82 In-house 43-231 (298) Show / Hide 
Range on Protein: 47-218
Range on HMM: 43-231/298
Sequence Identity: 41% (78 aa)

IALREIRLLKNLK-HPNLVSLLEVFRRKR--RLHLVFEFCELTVLHELERH----PQGCPEHL--TKQICYQTLLGVAYCHKQGCLHRDIKPENILLTA-
. ||||. |. |. |||.. |.||.| .   .|..|||... . | .. ..     .  ||     | | ||.|.| |..||.|  |||.|||||..|  
MNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMD-MNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGS

--------QGQVKLCDFGFARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLG
        |. .|..||| .|      .||||| ||||||||.|  .|.| .|.|.||.|| ..||    .|.|| | .||.. | | .|
QQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMG
Kinase CG7236.AA STE 4-289 22 2.1e-66 226.92 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-359/359
Sequence Identity: 22% (85 aa)

YEKLSRLGEGSYGVVYKCRDR------ETGAL---------VAVKRFVESEDDP---------------AIRKIALREIRLLKNLK--HPNLVSLLEVFR
.|.....|.|..|.|||....      .|| .         .|.|.   .....                ...  |.||...|...  ||| |  .  . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RKR-------RLHLVFEFCE-LTVLHELE-RHPQGCP------------EHLTKQICYQTLLG-VAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFAR
..         |... |...  ..   .. ..  |.|            |.. . ||.|.| |  .| |...  |||||| ||||     |||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

MLSP-----------------GENYTDYVATRWYRAPELLVG-----DTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTL----------
 |..                 ... .  | |  . ||| . .     | .|.| .|.| .||.  |.. |.  |   ..   ...| .            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GDL--LPRH------IQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTK--HSYF
   |.   || |      |.  | .            ... .      ...  |  .||..|||.||| ||.. ..| |  |. .
IVNGPPPPLPDHLSQNEMISY-G-G------------SGT-T-----YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CG7236.AA ERK7 4-289 35 6.1e-63 214.01 In-house 1-292 (292) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-292/292
Sequence Identity: 35% (106 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLK-HPNLVSLLEVFRRK--RRLHLVFEFCELTVLHELERHPQGCPE
|| ..||| | ||.| |  |. |.  ||.|.      ..       ||| .|.... |||...|..|.| .  | . ||||| | | ||   |. .   .
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFME-TDLHAVIRKGNILKD

HLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGE-------NYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAE
   . | || |  . | |    .|||.|| |||| ..  ||.|||| || ..  |         |.||||||||||| |.| ..|   || | |||  .|
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGE

LVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF
..|| .. || | ..|. .| .|..      |.  | .   . .        ..|.. || .....   || ||. |   | || . |.  .| | 
MLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP-QCCDD--AIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase CG7236.AA CDK7 104-218 53 6.3e-58 152.65 In-house 105-220 (288) Show / Hide 
Range on Protein: 104-218
Range on HMM: 105-220/288
Sequence Identity: 53% (62 aa)

KQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARML-SPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWP
| .  .||.|. |||.   ||||.|| | |.   ||.|. ||| ||   || ..||  | |||||||||| |  .||| ||.|..|| ||||       |
KAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLP

GRSDVDQLYLIRKTLG
| ||.|||  | .|||
GDSDIDQLTRIFQTLG
Kinase CG7236.AA CDK7 4-82 38 5.1e-33 84.93 In-house 1-83 (288) Show / Hide 
Range on Protein: 4-82
Range on HMM: 1-83/288
Sequence Identity: 38% (32 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFV----ESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLVFEF
|||.. .||| ...||| .| .||  ||.|.       || .  |   |.||| .|. ..|.| . |. .|  |  . |||.|
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDF
Kinase CG7236.AA Pkinase_Tyr 4-186 29 1.2e-22 77.37 Pfam 1-199 (270) Show / Hide 
Range on Protein: 4-186
Range on HMM: 1-199/270
Sequence Identity: 29% (59 aa)

YEKLSRLGEGSYGVVYKCRDR----ETGALVAVKRFVESEDDPA--IRKIALREIRLLKNL-KHPNLVSLLEVFR-RKRR--LHLVFEFCEL-TVLHELE
 ...  ||||..|.|||.. .    .|.  ||||   |. ....  ...  .||....|.| .|||.|.|. |   ...   . .|.|....   |. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF-MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RH---PQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPGENYTDYVAT------RWYRAPELLVGDTQYGTPVD
.|   .|  . .   |.|.|   | .| . ..| |||.   |.|.| ...|| |||| || . . ..|  ....      .|. ||| .     . |  |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM-APECINYGK-FTTKSD

VWA
||.
VWS
Kinase CG7236.AA TyrKc 4-289 21 4.2e-16 37.58 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-289
Range on HMM: 1-280/280
Sequence Identity: 21% (71 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNL--KHPNLVSLLEVFRRK-------RRLHLVFEFCE----LTVLHE
 ...  |||| .|.|||.. .     ||||   |.      |.  .||.|....|  .|||.| |. | . .         | .|.|...    .  |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPG-------ENYT------DY--VATRWYRAPELLVGD
 ...   |...|  ..|.|   | .| |...| |||.   |.|......|| .||| .| .  .       . |.          .  ||. ||| .  .
HRPK--LCMKDLL-SFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NY

TQYGTPVDVWAIGCLFAELV-RGEALWPG-----RSDVDQLYLIRKTLGDLLPRH---IQIFGQNEYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDFL
  . |  |||. | .  |.  .|.  .||      |. . . ....      | .   .                                  .   .  
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------F-VCCPDEMYQIM

KKCLDKDPTKRWSCEKLTKHSYF
|.| . || .| . . .  |..|
KQCWHEDPEDRPTFSEI--HECF
Kinase CG7236.AA RCK 4-34 45 1.7e-09 26.0 In-house 1-31 (298) Show / Hide 
Range on Protein: 4-34
Range on HMM: 1-31/298
Sequence Identity: 45% (14 aa)

YEKLSRLGEGSYGVVYKCRDRETGALVAVKR
|  ...||.|.||.| | .. ||| .|| |.
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKK
Kinase CG7236.AA CDK 264-289 50 8.8e-08 20.8 In-house 259-284 (284) Show / Hide 
Range on Protein: 264-289
Range on HMM: 259-284/284
Sequence Identity: 50% (13 aa)

DFLKKCLDKDPTKRWSCEKLTKHSYF
|.| |.|  ||.||.|.|   .| ||
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CG7236.AA CDK7 263-289 33 5e-06 11.62 In-house 262-288 (288) Show / Hide 
Range on Protein: 263-289
Range on HMM: 262-288/288
Sequence Identity: 33% (9 aa)

IDFLKKCLDKDPTKRWSCEKLTKHSYF
.|.... .  .| |||.|    |. ||
LDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CG7236.AA CDK5 264-289 38 0.000124 10.03 In-house 262-287 (287) Show / Hide 
Range on Protein: 264-289
Range on HMM: 262-287/287
Sequence Identity: 38% (10 aa)

DFLKKCLDKDPTKRWSCEKLTKHSYF
|.|.| |  .| .| | ..  .| ||
DLLQKMLQCNPNQRISAKAALHHPYF
Kinase CG7236.AA RCK 262-289 35 0.000403 8.65 In-house 271-298 (298) Show / Hide 
Range on Protein: 262-289
Range on HMM: 271-298/298
Sequence Identity: 35% (10 aa)

TIDFLKKCLDKDPTKRWSCEKLTKHSYF
.|. ..|.|  || || . ... .| ||
CIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CG7236.AA CDC2 263-289 44 0.004128 4.82 In-house 275-301 (301) Show / Hide 
Range on Protein: 263-289
Range on HMM: 275-301/301
Sequence Identity: 44% (12 aa)

IDFLKKCLDKDPTKRWSCEKLTKHSYF
|| |.. |  || || | ..  .| ||
IDLLMQMLQYDPQKRISAKEALQHPYF