Gene CkIIalpha (Fruit Fly)

CkIIalpha

Species: Fruit Fly
Alias: CkII, CKII, CG17520, SFO001, CKIIa, CK-2, CK2, CK2 alpha, Casein kinase II, NAP1-kinase, CkIIalpha, Cask-II-a, DmCKIIalpha, CK II, CK-II alpha, CKIIalpha
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 80A,

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
CkIIalpha.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 286 Kinase domain by global Sugen HMM Fasta, JSON
CkIIalpha.AA Protein Various 336 None Fasta, JSON

Protein domain

Protein domains of CkIIalpha.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CkIIalpha.AA CK2 37-322 80 1.6e-239 723.97 In-house 1-288 (288) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-288/288
Sequence Identity: 80% (231 aa)

YQLVRKLGRGKYSEVFEAINITTTEKC--VVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYY
|...||.||||||||||.|||...|||  |.|||||||||||||||||||||.||.|||.|...||||.|..|||.||.||||||.|||||||||.||||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

LFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGH
.||||||||||||||||||||||||.|||||.||||||||||||||||||.|||||||||.||||||||||.|||||||||||||.|||||.||||||||
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF
|||||||.|.||||||.||.|||||.|.|||.||||.|.|..|.||||.|..|.||..|||.|||||.||||| .|.||.||| ||||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CkIIalpha.AA CMGC 37-322 19 4.6e-100 329.56 In-house 1-513 (513) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-513/513
Sequence Identity: 19% (101 aa)

YQLVRKLGRGKYSEVFEAIN--------------ITTTEKCVVKILKPVKKKKIK---------------REIKILENLR----------------GGTN
|. ..|.|.| |..|.....              . | |.. .|..| .. ...                ||||||..|.                   |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IITLLAVVKDPVSRTP---------------ALIFEHVNNTDFKQLYQ-----------TLTDYE------------IRYYL------FELLKALD--YC
|..|. ..... |...                |.||.. .. .. ...            |.. .            |.|..      . .|..|.  ||
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSMG--IMHRDVKPHNVMIDHENRK-------------------LRLIDWGLAEFYHPG----------------------QEYNVRVASRYFKGPELLV
||..  |.||| || |..|.|...                    |...|.||| .|||                       . |  .|..|. . ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DYQMYD---------YSLDMWSLGCMLASM-------IFRKEPFFHGHDN-----------YDQLVRIAKVLG------------------TEELYAYLD
 .. |.         .. ||||.||..| |       |||..|.|.||..           .||| .| ||||                  .|| . ...
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

KYNIDLDPR---------FHDI-----------LQRHSRKRWERFVHSDNQ------------------------------HLVSPEALDFLDKLLRYDH
... ...|          ....           .... .| |....  ..                               .. .|.|.|.|.|.|.||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

VDRLTAREAMAHPYF
 .|.|| .|..||||
DKRITAEQALQHPYF
Kinase CkIIalpha.AA Pkinase 37-322 26 7.4e-89 306.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-293/293
Sequence Identity: 26% (82 aa)

YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKR-------EIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNT----DFK-----
|...||.|.| ...|...... | .. .|||.| ...|. |.       ||.|. .| .  ||..|. .. |  .. . ...|.....    | .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

QLYQTL--TDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRK---LRLIDWGLAEF--YHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDM
. . ..  .. |.. |. ..|..|.|||||||.|||.|| |..||...     ....|.|||..  | ... ..... ....  ||.. ..|.|... ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCMLASMIFRKEPFFHG---HDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDR
||.||.|. |.... || .    .. .||...|....|..  . .  ...| ... | .   .        | |. . |..|.|..||....|..|  .|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

LTAREAMAHPYF
.||.... ||.|
PTAEQILQHPWF
Kinase CkIIalpha.AA S_TKc 37-322 25 1.1e-75 258.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-231/231
Sequence Identity: 25% (77 aa)

YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNN--TDFKQLYQT---------
|...||.|.| ...|. .... | ... .||.|    ..|.|||.||..  .  ||..|. |  |       ...|....   | ... .          
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDY-SLDMWSLGCMLASMI
..  ..|.|. ....||.||||.||.|||.|| |...|.    . ..| ||| ..      .  . ....  ||.|     |.. . |.||.||.|. |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMA------
 .. ||        |. .. |..|                                           ||||.||..|.|..|  .|.|| ||..      
CGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYF
 ||.|
CHPWF
Kinase CkIIalpha.AA CDK 37-322 26 5.2e-54 171.12 In-house 1-284 (284) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-284/284
Sequence Identity: 26% (86 aa)

YQLVRKLGRGKYSEVFEAINITTT-----EKCVVKILK-PV-----KKKKIK----REIKILENLRGGTNIITLLAVVKDP-VS--------RTPALIFE
|. . |.|.| | .|. |..  |      . .  | ..        .|  .     |||..| .|    ||..|. |. .   .        ..  ..||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

HVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENR----KLRLIDWGLAEFYH-------PGQEYNVRVASRYFKGPELL
..  .| |..        |. |.. ||..|.|||| .||||| || | .|..       .| . | |||  ..       | ..|  .|  .    ||||
YM-DHDLKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELL

VDYQMYD--YSLDMWSLGCMLASMIF--RKEPFFHGHDNYDQLVRIAKVLGT--EELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEA
   . |.   . ||||.|| .| |.    ..|.|.|    ||| .| ...||  |.    . |.                                    
LGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------------

LDFLDKLLRYDHVDRLTAREAMAHPYF
 |.|.|.| ||   |..| .|. ||||
-DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CkIIalpha.AA CAMK 42-230 20 3.1e-50 159.68 In-house 1-334 (425) Show / Hide 
Range on Protein: 42-230
Range on HMM: 1-334/425
Sequence Identity: 20% (67 aa)

KLGRGKYSEVFEAINITTT------------EKCVVKILK-------------------------------PVKKKKIKREIKILENLRG------GTNI
.|||| ...|...|.. ||            .|. .||..                               |...|...|||.|. .|.|        ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITLLAVVKDPVS--------RTPA----------LIF---EHVNNT----D-FKQLYQT-----------------LTDYEIRYYLFELLKALDYCHSMG
| |. |  ||                        ...   |.. .     | |  . .                  .|  | |.|   .. |..||||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPHNVMIDHEN----------------RKLRLIDWGLAEFYHP------------------------GQEYNVRVASRYFKG-PELLVDYQM--
|.||| || |...|. |                 .. .||.|.| .. |                        || .. .. . ..   ||.|   ..  
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YDYSLDMWSLGCMLASMIFRKEPF
           |... ||||.|..|  |   . ||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase CkIIalpha.AA CDK5 37-322 29 3.3e-40 124.43 In-house 1-287 (287) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-287/287
Sequence Identity: 29% (90 aa)

YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKK-----KKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDY--
|. . |.| | |  |. | | .| |    |  .             ||| .|  |.   ||. |  |.     .   |.||.. . | |     ....  
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIH--SEKKLTLVFEFCDQ-DLKKYMDSCNGEMD

--EIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAE-FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR
   |..... ||| | .||.  ..||| || | .|   | .|.| | |||  |  | . |   |    .  |  |   ..|  | |||| || .| |.  
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINK-NGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

KEPFFHGHDNYDQLVRIAKVLGT--EELY---AYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPY
  | | | |  ||| || |..||  |.     . | .|..  ...      .. .. |.  |.. ....     .|.| |.|...   |..| .|. |||
GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQY----PMYPAHQSWQQIVPKLDEKG-----MDLLQKMLQCNPNQRISAKAALHHPY

F
|
F
Kinase CkIIalpha.AA Ciliate-E2 37-322 17 1.6e-39 133.31 In-house 1-365 (365) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-365/365
Sequence Identity: 17% (73 aa)

YQLVRKLGRGKYSEVFEAINITTTE------------------KCV-----VKILKPVKKKKIKREIKILENLRGGT----------------NIITLLA
| ...|.|.| .. |... .. . .                  |.      .||.|. ... ||.||.|.  ..                   ||| .  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

VVKDPVSRTPALIFEHVNNTDFKQLYQ--------------TLTDYEIRYYLFELLK---------------ALDYCHSMG-IMHRDVKPHNVMIDHENR
. ..    .  |..| ..  | ... .               .|..||.|.  ..|.               || |.|| . |.||| || |...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KLRLIDWGLAEFYHPGQE--------------------------------YNVRVASRYFKGPELLV--DYQM------YDYSLDMWSLGCMLASMIFRK
 . .||.||. .|.. ..                                .|  . . ... || |   .|.       |||. |.||||..|  |.| |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

EPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHL---------------------------VSPEALDFLD
 ||                                                        .|..                           .|.|. |.. 
PPF-------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIK

K----LLRYDHVDRLT-AREAMAHPYF
|    .| .|   |.| . ... ||.|
KFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CkIIalpha.AA Ciliate-E2-Unclassified 37-322 18 3.5e-36 123.03 In-house 1-352 (352) Show / Hide 
Range on Protein: 37-322
Range on HMM: 1-352/352
Sequence Identity: 18% (69 aa)

YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKK---------IKREIKILENLRGGTNII---TLLA----------VVKDPVSRT----PALI
| .....|.| ...|...... . .. . |..| ....|         |..|.|...|. .  .      ..           .||.    .    . ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

FEHVNNTDFKQLYQT--------------------LTDYEIR-----YYLFELLKALDYCHSMG-IMHRDVKPHNVMIDHENR--KLRLIDWGLAEFYH-
 | ... | .|  .                     .|.....     .|. ..|..|.|.|. . | ||| || |...| ...  ....||.|.. .|  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PGQEYNVRVASRYFK----GPELLVDYQMYD----YSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDK
               . |... .. . ...     ||.| . | ||    |. |.||||. |  |.| . ||.   .. .| . .... .          
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL-QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-N----------

YNIDLDPRFHDILQRHSRKRWERFVHSDNQ--HLVSPEALDFLD----KLLRYDHVDRLTAREAMAHPYF
  ..   ..  ..|    | .. . ..  |  . .|||| ||.     |.| ..   |.|. ... ||.|
--NA---YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CkIIalpha.AA CAMKL 37-230 27 4e-34 106.19 In-house 1-236 (297) Show / Hide 
Range on Protein: 37-230
Range on HMM: 1-236/297
Sequence Identity: 27% (65 aa)

YQLVRKLGRGKYSEVFEAIN-ITTTEKCVVKILKPVKKKK------------------IKREIKILENLR--GGTNIITLLAVVKDPVS----RTPALIF
|.... ||.| ...|  |.. .|| ||  .||..  |...                  |.|||.|.. |.  .  ||| |. |. .|          |. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EHVNNTD---FKQLYQT------LTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENR-KLRLIDWGLAEFYHP-----GQEYNVRVASRYFK
|.. . .   |  . .       ..  | | |   .. |..||||.|| ||| || |...|. .. .. .|| |.. .| |     ||  . .  |  . 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

GPELLVD-YQMYD-YSLDMWSLGCMLASMIFRKEPF
 ||.. .  . || .  |.||.| .|  |.. . ||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Kinase CkIIalpha.AA CDC2 37-249 29 9.1e-34 100.77 In-house 1-227 (301) Show / Hide 
Range on Protein: 37-249
Range on HMM: 1-227/301
Sequence Identity: 29% (68 aa)

YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIK--------REIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQ----
|| ..|.| | | .|. ...  | . ...|  . ..             ||| .| .|.   ||..|  |..    .   ..|| . . | |..      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIP

---TLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA-EFYHPGQEYN--VRVASRYFKGPELLVDYQMYDYSLDMWSLGC
    ..   .. |.. .|.....||...||||| || |  || . . ... | |||  |  |  .|     |  .    ||.|   . |. . ||||.||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

MLASM-IF-RKEPFFHGHDNYDQLVRIAKVLGT
 .| | .   |.|.|||    ||| .| ..|||
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGT
Kinase CkIIalpha.AA GSK 192-322 29 6e-28 81.96 In-house 181-328 (328) Show / Hide 
Range on Protein: 192-322
Range on HMM: 181-328/328
Sequence Identity: 29% (46 aa)

SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---EELYAYLDKYNIDLDPRFHDI-LQRHSRKR---------
|||   |||. ... |. . |.||.|| .| |. .. |.| |..  ||||.|.|.|||   |.. .   .|.   .| . .. . .|. ..         
SRYYRAPELIFGCTNYTCQIDVWSCGCVMAEMLKGQ-PLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQT

----------WERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF
            . .|.|.|     ...|.. |.|.||   ||...||.|||.|
YYHKKYRTVYMFKWCHTDMQ-----DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase CkIIalpha.AA GSK 124-175 36 2.4e-14 39.64 In-house 111-162 (328) Show / Hide 
Range on Protein: 124-175
Range on HMM: 111-162/328
Sequence Identity: 36% (19 aa)

QTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWG
|......|..| . ....| | ||.|| |||.|| |. .|... .| . | |
QQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFG
Kinase CkIIalpha.AA CDC2 287-322 47 4.5e-12 32.86 In-house 266-301 (301) Show / Hide 
Range on Protein: 287-322
Range on HMM: 266-301/301
Sequence Identity: 47% (17 aa)

NQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF
||  . ||..| |...|.||  .|..|.||..||||
NQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CkIIalpha.AA CAMK 291-322 34 6.4e-11 30.69 In-house 394-425 (425) Show / Hide 
Range on Protein: 291-322
Range on HMM: 394-425/425
Sequence Identity: 34% (11 aa)

VSPEALDFLDKLLRYDHVDRLTAREAMAHPYF
||.|. |.. |.|..|  .|.|. ....|| .
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CkIIalpha.AA TyrKc 37-274 16 5.1e-10 -60.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 37-274
Range on HMM: 1-280/280
Sequence Identity: 16% (46 aa)

YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENL-RGGTNIITLLAVVKDP-----VSRTPALIFEHVNNTDFKQLYQTLTD--
 .| .|||.| . ||.... .   ... || ||. ... . ||..|. .|     ||. |..|. ..      .  . ...|.. . | |.  .   .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

--YEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPG-------QEYNVRV--ASR-----YFKGPELLVDYQMYDYSLD
   .  .. .   .  .| ||... |||    |.......   .  | ||. . . .       . | ..    ..         || . .| ..    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

MWSLGCML---ASMIFRKEPF-----FHGHDNYDQLVRI----AKVL--------GTEELYAYLDK---YNIDLDPRFHDILQRH
 || | ..    .      |          . . .. .                  ..|.|    .   .. .  |.| .| .. 
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CkIIalpha.AA CAMKL 291-322 31 2.8e-07 19.1 In-house 267-297 (297) Show / Hide 
Range on Protein: 291-322
Range on HMM: 267-297/297
Sequence Identity: 31% (10 aa)

VSPEALDFLDKLLRYDHVDRLTAREAMAHPYF
|| .. |.. |.|  .  .| |. . | || .
VS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase CkIIalpha.AA GSK 37-96 24 3.3e-05 11.21 In-house 1-70 (328) Show / Hide 
Range on Protein: 37-96
Range on HMM: 1-70/328
Sequence Identity: 24% (17 aa)

YQLVRKLGRGKYSEVFEAINI----TTTEK----CVVKILKPVKKKKIKREIKILENLR--GGTNIITLL
|.  .. |.|  . |..|...    .| |.     ..|   . |. |  || .|...|.     ||..|.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLK