Gene CG10522 (Fruit Fly)

CG10522

Species: Fruit Fly
Alias: Citron, SFO184, CG10522, CITRON
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 69C4,

Classification

Group: AGC
Family: DMPK
Subfamily: CRIK

Sequence

Name Sequence Type Origin Length Description Download
CG10522.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
CG10522.AA Protein Various 1854 None Fasta, JSON

Protein domain

Protein domains of CG10522.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG10522.AA DMPK 113-379 50 3.5e-246 617.41 In-house 1-270 (270) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-270/270
Sequence Identity: 50% (141 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKK----SVVTTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHG-PFDED
| |...||.|.||.|..|...||||.||||...|    ....|....||||||...||.|...|.|||||...||.|||||||||||.||||.. ...||
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

LARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGY
.|||||||...|.|..|.||||||||||.|.|.||.|||||||||......|||.| |...|||||||.||.||..... . |......||.||.|...|
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNRDGMVRSKVAVGTPDYISPEVLQAMEDD-G-KGRYGPECDWWSVGVCMY

ELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLK--VSVNYRNLIESLVTNPSKRLS---YERIKNHPFF
|.....|||..|...|||.||..||     |. .|||.| |  ||.....||..|......||.   ||..|.||||
EMLYGETPFYADSLVETYGKIMNHC-----KNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF
Kinase CG10522.AA CRIK 113-379 68 3e-244 787.24 In-house 1-272 (272) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-272/272
Sequence Identity: 68% (185 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQ----VKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHG-PFDED
|..|.|||.|.||.|..|.|.|||||||||...|.||....    ..|||||||.|||.||..|||||||||||||.|||.|||||||||.||. .|||.
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

LARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGY
.||||||||.||.|.||||||||||||||||||||.|||||||||.||...|..||.|..|||||||.|||.|||...|||||.|..|.||.||||||.|
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAKMNRNNHVNSKMPVGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAY

ELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRLSYERIKNHPFF
|..|..|||||||.|.|||.|..||||||.....|||.|.|||.|||.||.||..|.||||.||....||||
EMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRLKYEQLCCHPFF
Kinase CG10522.AA AGC 113-379 28 1.2e-149 389.94 In-house 1-395 (395) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-395/395
Sequence Identity: 28% (117 aa)

FLIKTLIGQGYFGNVHLVVER------QTNDIYAMKKIKKSV---------VTTSQ----------VKEERDIMSIRN----------SEWLIN-LQYAF
| ....||.| || |.|| ..      .|...||||..||..         |   .          |.|||.|..  |          . .... | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDNDN--LYLVMEYMP---------GG-DLLSLMS---RHGPFDEDLARFYLAE-------LTVALHTLHE-MGYVHRD-IKPENILIDRFGHIKLADFG
||.|.  ||.||||||         || .|.. .    . | |||. ||||.||       .. ||. ||. ||..||| .||||||.|. |||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

NAAALDRDG-------------------------------------------------HVLSLSPVG--TPDYIAPELLQTISTYKLSKSMHDVSCDYWS
 .  . .||                                                 ...  . .|  ||.|.||| |            .. .||.||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL------------YGKACDWWS

--MGIIGYELICETTPFHEDN----------VHETYSKILSHCEESHLKELISFP------ADLKVSVNYRNLIESLVT-NPSKRLS----------YER
  .|.. ||...  .||. ||           .|.. ||...  ... |. . ||      .| ..|.. ..||. | . .|.|||           .| 
FGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEE

IKNHPFF
|||||.|
IKNHPWF
Kinase CG10522.AA S_TKc 113-379 30 1e-90 308.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-231/231
Sequence Identity: 30% (88 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPG--GDLLSLMSRHGP------F
. |  .||.| || |...... |. |.|.|.||       ... |..|..  . .....| ..||| |.||.||||..|  |||.... ..|.      |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDV-SCDYWSMG
.|  ||||....  ||  .|..| .|||.||||||.|.  |||..||| |. |         . .|||.|.|||.|            ..  .|| || |
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL-----------GYGKCKCDWWSCG

IIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVT-NPSKRLSYERIKN-------HPFF
.| ||..|  .||.  ...... ||.                    |   ...|. . . .|.||..   . .       ||.|
CILYEMLCGYPPFP--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG10522.AA ROCK 113-379 41 6.8e-88 298.3 In-house 1-263 (263) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-263/263
Sequence Identity: 41% (115 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVT----TSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDL
| .  .||.| || |.|| ..... .|||| . |  .          ||||||   ||||.. |.|||||.  ||.||.||||||| .|||      |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYD-VPEKW

ARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGYE
|||| .|.  || ..|.||..|||.||.|.|.|. ||.||||||    ....| | .   |||||||.|| |.  .      . .   ||.||.|.  ||
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNKNGMVRCDTAVGTPDYISPEVLKSQGQ----DGEYGRECDWWSVGVFIYE

LICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVTNPSKRL---SYERIKNHPFF
..   |||  | .  |||||. |      |. ..|| | ..| . ..||   .|.  .||   . . ||.|.||
MLVGDTPFYADSLVGTYSKIMDH------KNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQHKFF
Kinase CG10522.AA GEK 113-379 42 4.5e-87 292.34 In-house 1-269 (269) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-269/269
Sequence Identity: 42% (118 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKK----SVVTTSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGP-FDED
| |  .||.| || |  |  ..|...|||| ..|        |.  .||||..    . |. || |||||...|||||.|  ||||| |.|. .    ||
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

LARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGY
.||||.||. .|.. .|...||||||||.|.|.|. |||.|||||    ...|| | |   |||||||.||.|| .      |      ||.||.|.. |
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNKDGMVQSNVAVGTPDYISPEILQAMEDG---KGRYGPECDWWSLGVCMY

ELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLK---VSVNYRNLIESLVTNPSKRLSYERI---KNHPFF
|..  .|||  . . |||.||..|      |. ..||.. .   || . . ||..|.  . .||  . |   |.||||
EMLYGETPFYAESLVETYGKIMNH------KDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF
Kinase CG10522.AA NDR 113-252 49 3.3e-76 234.39 In-house 1-149 (350) Show / Hide 
Range on Protein: 113-252
Range on HMM: 1-149/350
Sequence Identity: 49% (74 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVT----TSQVKEERDIMSIRN--SEWLINLQYAFQDNDNLYLVMEYMPGGDLLS---LMSRHGP
| | ..||.| || | || .. |..|||||...|| .     . .|. |||||.. .  ..|   | |.||| ..|||||||.||||. .   | .. . 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFG
|.||.|||| ||...|.. .|.|||.||||||.|.|||. ||||| |||
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase CG10522.AA RSK 115-379 33 1.1e-74 254.44 In-house 1-278 (278) Show / Hide 
Range on Protein: 115-379
Range on HMM: 1-278/278
Sequence Identity: 33% (96 aa)

IKTL--IGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQV-----KEERDIMSIRN-SEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGP---
.| |  .|.| .  .. .. ..|. ||||| .||... ..|.     ..||.|..  . .  ...| ||||... |||.|||..||.|.   ....    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDR---FGHIKLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDVSCDYW
|.|| |.||.||...|.  ||. | .|||.|||||| |     ||||| ||| .  .. |   .  ....| .|.|||.| .   .   .. || .||.|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKR--AN--QQGGHDKACDWW

SMGIIGYELICETTPFHE---DNVHETYSKILSHCEESHLKEL--ISFPADLKVSVNYRNLIESLVT-NPSKRLS-----YERIKNHPFF
| |.. ||.    .||.    .| .|.  .|        .|     ..|.. ..| . ..||  . . .|.|||.      |.||.||.|
SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRI--------QKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CG10522.AA Pkinase 113-379 30 2e-69 241.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQVKE-----ERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGG----DLLSLMS--RH
. |.  ||.| || | . ... |..|.|.|.|||.    .. ..     |  ||   |..  . | ..|.|.|..|.||||..||    || ...|  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPF--DEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHI----KLADFGNAAALDRDGHVLSLSPVGTPDYIAPELLQTISTYKLSKSMHDV
|.|  .|. ..||. ..  .|  .|.|| .|||.||||||||. |||    |..||| |. .|    .   ...|||.|.|||...       . .... 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-------GGQYYGP

SCDYWSMGIIGYELICETTPFHED------NVHETYSKILSHCEESHLKELISFP------------ADLKVSVNYRNLIES-LVTNPSKRLSYERIKNH
..| ||.|.| ||..|  .|| ..      .  . . .|..   ...  ...| .               ..| . . .|.. |  .|.||.. | |..|
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PFF
|.|
PWF
Kinase CG10522.AA CAMK 118-379 21 2.8e-69 222.14 In-house 1-425 (425) Show / Hide 
Range on Protein: 118-379
Range on HMM: 1-425/425
Sequence Identity: 21% (94 aa)

LIGQGYFGNVHLVVERQTN------------DIYAMKKIKKS-----------------------------VVTTSQVKEERDIMSI-------RNSEWL
 .|.| || |.|.....|.              .|.| |.|.                              ..  .|. | .||.         . . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INLQYAFQD-------------------NDNLYLVM---EYMPGG----DLLSLMSRHGP---------------FDEDLARFYLAELTVALHTLHEMGY
|.|  ...|                   ....|.||   ||..||    ||..   .||.               |.|. ||.|   .  |.| .|... 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPENILID-RF----------------GHIKLADFGNAAALDRDG----------------------HVLSLSPVGTPDYIA-PELLQT------
||||.||||||.| ..                . ||..||| |. .|..                         .   ..||| |.| ||.|.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--ISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHED-------------NVHETYSKILSHC-E-ESHLKELIS--------------FPADLKVSV
  . |    |  .. .|| ||.|.| | . | . || .|             | .|.. ||..   . ...    ||              |    .|| 
QNA-T-DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF-HH-FVSQ

NYRNLIESLVT-NPSKRLSYERIKNHPFF
  ..|| .. . .|.||.. | ..|||..
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CG10522.AA MAST 113-254 40 5.9e-60 181.57 In-house 1-149 (337) Show / Hide 
Range on Protein: 113-254
Range on HMM: 1-149/337
Sequence Identity: 40% (61 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTS----QVKEERDIMSIRNSEWLINLQYAFQD--NDNLYLVMEYMPGGDLLSLMSRHG-PFD
| .. .|. | .| | ||  . |||..|||.|...         ||. ||.| ..   ..  .. |.||    . |..||||| |||  ||..  | ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNA
|..|..|.||.  .|  ||..| ||||.||.|.|||  |||||.|||..
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase CG10522.AA MAST 113-254 45 3e-58 186.23 In-house 1-146 (334) Show / Hide 
Range on Protein: 113-254
Range on HMM: 1-146/334
Sequence Identity: 45% (66 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTS----QVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDL
| .. .|. | .| | ||  . |||..|||.||||         ||. ||.| ..  ...  .. |.||  ..|..||||| |||. ||..  |.|||..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNA
|..|.||.  .|  ||..| ||||.||.|.|||  |||||.|||..
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase CG10522.AA NDR 267-379 35 5.2e-27 79.8 In-house 240-350 (350) Show / Hide 
Range on Protein: 267-379
Range on HMM: 240-350/350
Sequence Identity: 35% (43 aa)

SPVGTPDYIAPELLQTIST-YKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPADLKVSVNYRNLIESLVT-NP
| ||||||.||| .|   | |       . .||.|| | | ||...  .||. |.. ||. ||. ....   . ...||.. ..|.   .||. |.. .|
STVGTPDYMAPEVFQQ-KTGY-------NQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIM-NWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDP

SKRLS-----YERIKNHPFF
..||       . ||.||||
DHRLGSHGKGVDEIKSHPFF
Kinase CG10522.AA MAST 269-379 34 2.8e-21 65.06 In-house 225-334 (334) Show / Hide 
Range on Protein: 269-379
Range on HMM: 225-334/334
Sequence Identity: 34% (42 aa)

VGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFPAD------LKVSVNYRNLIESLVT
.|||||||||..   .|       |  . |.|||||| ||... ..|| .|.. |....||..         |..| .       . |.  . ||| | .
CGTPDYIAPEVILGQGT-------HGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNC-----NEIEWPEGGDINDDEAMSPEAQDLIEKLLQ

N-PSKRLSYE----RIKNHPFF
  |.|||        .|.||||
PDPRKRLGANNGADEVKQHPFF
Kinase CG10522.AA MAST 269-379 34 7.6e-21 59.82 In-house 229-337 (337) Show / Hide 
Range on Protein: 269-379
Range on HMM: 229-337/337
Sequence Identity: 34% (42 aa)

VGTPDYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHE-TYSKILSHCEESHLKELISFPAD------LKVSVNYRNLIES-L
.||||||||| .  ..|       .  . |.|||||| ||... ..|| .|.. | . ..|..|      .. |..| .       ..|   . ||.  |
CGTPDYIAPEVILGQGT-------YGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINH------DREIEWPEEGDPNDDDCMSPEAQDLIKKLL

VTNPSKRLSYE---RIKNHPFF
  ||.|||       ||.||||
QPNPKKRLGANGADEIKQHPFF
Kinase CG10522.AA TyrKc 113-379 18 2.4e-11 -39.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 113-379
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

FLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVVTTSQVKEERDIMSIR--NSEWLINLQYAFQDN-------DNLYLVMEYMPGGDLLSLMSRHGP
   .  .| | || |.. . .      | |..|..        .|  ||.    . . ...|  .  .        . |..||||||.|||..   .|.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-FDEDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRD-------GHVLSLSPVGTPD-----YIAPELLQTISTYKLSK
 .  .    .          ||.....|||.   |.|... ...| .||| . ... |           . .  |. .       ||| .         .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--------NY

SMHDVSCDYWSMGIIGYELI-CETTPFHE-----DNVHETYSKILSH----CEESHLKELISFPADLKVSVNYRNLIES-LVTNPSKRLSYERIKNHPFF
..     | || |.  .|.     .|  .      .  | . .. .     . .... . .||      .    .....    .|..| . . |  | .|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CG10522.AA Pkinase_C 397-451 20 1.8e-08 33.09 Pfam 1-46 (46) Show / Hide 
Range on Protein: 397-451
Range on HMM: 1-46/46
Sequence Identity: 20% (13 aa)

TVRSDDDTSNFED----------GIRHKTRREQGVAKKSLTTNMKSNDFSGKDLPFIGYSFVHME
.|.|..|||||..                             ....  .||...||.|...|. .
QVKSPTDTSNFDPEFTDEPPMDTP------------------PDWR-MSSGDQEPFRGFTYVNPD
Kinase CG10522.AA S_TK_X 380-449 18 1.5e-05 24.48 SMART 1-79 (79) Show / Hide 
Range on Protein: 380-449
Range on HMM: 1-79/79
Sequence Identity: 18% (15 aa)

SEIPWGSIRS----QVPPIIPTVR----SDDDTSNFE-DGIRHKTRREQGVAKKSLTTNMKSNDFSGK--DLPFIGYSFVH
..| |  ...      ||..|...    |. |||||. .  . . . .. . . .. ..  .   .    ..||.|...|.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNE-METEIPPDPFRGFTYVF
Kinase CG10522.AA Pkinase_Tyr 179-203 46 0.000309 14.97 Pfam 80-106 (270) Show / Hide 
Range on Protein: 179-203
Range on HMM: 80-106/270
Sequence Identity: 46% (13 aa)

NDNLYLVMEYMPGGDLLSLMSRH---GP
| ..|.||||||.||||.   .|   ..
N-QIYIVMEYMPHGDLLDYLRKHREDKQ
Kinase CG10522.AA Pkinase_Tyr 223-252 33 0.000484 14.31 Pfam 127-156 (270) Show / Hide 
Range on Protein: 223-252
Range on HMM: 127-156/270
Sequence Identity: 33% (10 aa)

LHEMGYVHRDIKPENILIDRFGHIKLADFG
|......|||.   |.|... ...| .|||
LESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase CG10522.AA Pkinase_Tyr 113-129 29 5.560367 0.56 Pfam 1-17 (270) Show / Hide 
Range on Protein: 113-129
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

FLIKTLIGQGYFGNVHL
  .   .|.| ||.|..
ITFGKKLGEGAFGEVYK
C1 CG10522.AA C1 1385-1436 18 2e-05 25.13 SMART 1-61 (61) Show / Hide 
Range on Protein: 1385-1436
Range on HMM: 1-61/61
Sequence Identity: 18% (12 aa)

HRFELALQESKVDAVNCVVCEKAVVAG------SPFWKCKECKDVTHRKCRSNVQS-------HC
|...           .| .|.| .  .      .. ..| .|| . | || ..|..        |
HHWHWWRF----KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
CNH CG10522.AA CNH 1499-1777 18 3.8e-64 224.23 Pfam 1-336 (336) Show / Hide 
Range on Protein: 1499-1777
Range on HMM: 1-336/336
Sequence Identity: 18% (63 aa)

AFEVAEQQILLLG-CNTGLYAYHL----DSQRLVHISGLES--VSCMSICKRLAKAIMV--GTVGEKLYQCDYRQLESRCQSSSSCHKPVLET-------
.. .  .|.||.| ...||| |..    | . ...|... |  |... ..... . ||.     . .||... ..|....|....||.|  ..       
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSRRVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRIERI

------SAIELPFANRTPSEKWKLVLISDEAENALDSVAIAATS----TRIVILKYDLKLHMF-------------KPVRA-LDTA----TPVTSIFFT-
        . || .. .   .|        . .     ..|. .    ..|......  ...|             ...|  ...     |...|. .. 
MPRKFAMWQKLPDTKHCHFFCW-----IRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLP

--RHSAIVS-SDKFYEIDLD-NYAAEEFVDLSDKS-----MESTAKCQPLTAVRISRQ-EYLLCFAEYGVFVDEFGC-RSR--PYDLNWVYAPTGFVYRD
  ... .|. ...|. ..|| ........|..|.|     |... .|.|....||... |.|||. |..|.|. .|. |||  . ...|. .|. |....
QEKPKLCVGCQKGFHIVNLDGTGQPWWLHDPADHSVQQDFMARRENCKPICMHRINDDEEFLLCYDECCVYVNKQGWPRSRKHDWEIMWEGMPQSFACCY

PFLFISHYQSVQIVRLHRSFS-----KEMASGDNASENSESP
|.|.. |  ...|  .. . |      .. .|.|.    .. 
PYLLAFHPNFIEIRHVETG-SEWDACVQCIPGQNIRFLHSGS
CNH CG10522.AA CNH 1494-1804 14 1.4e-08 24.83 SMART 1-375 (375) Show / Hide 
Range on Protein: 1494-1804
Range on HMM: 1-375/375
Sequence Identity: 14% (56 aa)

IEVNCAFEVAEQQ----ILLLGCNTGLYAYHLDSQ-------RLVHISGLESVSCMSICKRLAKAIMVGTVGEK--LYQCDYRQL----ESRCQSSSSCH
  ...  ..  .|    .||.| ..|.|.  .. |        ..|| .  .|.||.. . . . .|.  .|.|  || ..   |    . . ..     
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMI--SGKKPHLYSHPLVWLFQKYRTQGMTPH-IQ

KPVLETSAIELPFANRTPSEKWK--LVLISDEAENAL--DSVAIAATSTRIVIL-KYDLKLHMFKPVR------------------ALDTATPVTSIFFT
  .  .  .. ...  |  .  |   ..  . ....     .  .|... ..|.  ..  .| |. ..                  .. . .||...|  
DHMCNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHH

RHS----AIVSSDK----FYEIDLDNYAA----------EEFVDLSDKSMESTAKC--------QPLTAVRISR------QEYLLCFAEYGVFVDEFG--
. .     .. .||    .|...  ..            |..|...|.| ... ..         |. .... .       .||||. . ||||.. |  
DSFERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSE

-CRSRPYDLNWVYAPTGFVYRDPFLFISHYQSVQIVRLHRSFSKEMASGDNASENSESPELQ---RVYLPHYMSTLLANSGDVNLYAVA
  |.|. .| |  .|..|.|..|.... .  ..||. .           .... |  ..      .   ... .| . ..... .    
WRRWRNPILHWEFMPEYFAYHYPYIMAFWDNGIQIRHI-----------KTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP