Gene CG17090 (Fruit Fly)

CG17090

Species: Fruit Fly
Alias: SFO081, CG17090, HIPK
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 61C3--5,

Classification

Group: CMGC
Family: DYRK
Subfamily: HIPK

Sequence

Name Sequence Type Origin Length Description Download
CG17090.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
CG17090.AA Protein Various 1320 None Fasta, JSON

Protein domain

Protein domains of CG17090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG17090.AA HIPK 192-520 77 9.3e-250 795.69 In-house 1-329 (329) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-329/329
Sequence Identity: 77% (255 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
|||||||||||||||||||||||.|.||||||||||.||||||||||||..||||||||..||||.|||.|||||||||||||||||||.|||||.||||
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPL

KYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGW
|.|||||.||||||.|||.||||||||||||||||||.|.|||||||||||||||||.||||||||||||||||||||||||..||||||||.|||||||
KHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGW

PLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRR
|||||..|.||||||.|||.||.||.|..|.|. .|| || .| .. ||||. ||||..|  |||||||||||||||. .||. .|.|. ....|| |||
PLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKYIFNCLDDMPEVNMLVDPERQDYRVEKIDRR

EFIDLLKRMLTIDQERRLTPAEALNHSFT
||...||.|.|.|...|.||.|||||.|.
EFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase CG17090.AA DYRK 192-520 40 1.6e-182 612.63 In-house 1-320 (320) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-320/320
Sequence Identity: 40% (137 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQE-NADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPL-
||.||..|.|.||||||||...| |.|||||..|.....||.|||..||..|.|. . |....|.....|.|.||.|.|||.|..|||.|||.|.| .. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

PLKYIRPILEQVLTALLKLKQL-GLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELF
.|...|... |.||.|..|...  .||.|||||||||..| |.....|||||||...... .. ||.|||.|||||.|||.|.|.|||||||||..||||
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQP-RNKSTIKVIDFGSSCFEHQ-RIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELF

LGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSA--SKTSKFFYRDVDSTYPFWRLKTTEEHEAETN-TKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLA
.||||.||..|.||...| ...|.|...|....  ... ||| .           .. .|.. .|.  |........... ... ... | . . .  . 
TGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-----------FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRH

EKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFT
. .|...|.|..|..|..| ..|.||..||.|.. 
Q-CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase CG17090.AA CMGC 192-520 22 6.7e-111 365.82 In-house 1-513 (513) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-513/513
Sequence Identity: 22% (117 aa)

YEVLEFLGRGTFGQVVKCWK--------------RGTSEIVAIKILKNHPSYARQGQ-------------IEVSILSRLS------------QENADEFN
||... .|.||.|.|.||.               . | ||||||..|| . | .|..              |..|| .|.             .| .. |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

FVRAFECFQHKN-----------------HTCLVFEMLEQNLYDFLKQNK--------------------------FSPLPLKYIRPILEQVLTALL--K
 |. ...|.|||                 | .|||| ....||...|.|.                             ... .|| .  |.|..|    
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LKQLG--LIHADLKPENIMLVDPVRQP----------------YRVKVIDFGSASHVSKT-----------------------VCNTYLQSRYYRAPEII
. . .   || |||||||.. .  . .                .|.|..|||.| ....                           .| ..|.||||||.
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LGLP----------FCEAIDMWSLGCVVAELFLG--------WPLYPGSSE-----------FDQIRYISQTQGLPTEHMLNS-------ASKTSKFFYR
|| .          ....|||||.||. ||...|        .|| ||.||            ||.  | .. | || .|...       .... .....
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNM

DVDSTYPF------WRLKTTEEHEAETNTKSKEARKYIFN-CLDDIGQVNVPTDLEGGQLL----------------------------AEKTDRREFID
    .|.       |      .  ..||..|. ||.||.. .     . .  ..|. ..                              ..| .  ..||
IKLPWYNKFPKKWNW------Q--TMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAID

LLKRMLTIDQERRLTPAEALNHSFT
|||.||..| ..|.|...||.| . 
LLKKMLQYDPDKRITAEQALQHPYF
Kinase CG17090.AA YAK 192-520 38 1.8e-101 343.41 In-house 1-347 (347) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-347/347
Sequence Identity: 38% (136 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRL-SQENADEFN----FVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKF
| ||  ||.||||||||| . .| |..|.|..|| . |  |.  |. ||  |  |.  .. |    ..|    | |||| |||||||. |||..||||||
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

SPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAE
  .    ||  . |.| ..  |.   .|| |||||||||   . .|  .|.|||||.    |.|  || |.|.||.||||.. ..| .||||||||.|||
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCK-PNKP-EIKIIDFGSSCQEKKMVY-TYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAE

LFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVD---------------STYPFWRLKTTEEHEAETNTKSKEARKYI-FNCLDDI-
|||| |..|| ||..||  |  . | |.  |..      |.| .                    |    .|| .. . .  .. || ..|  . || || 
LFLGLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYFHCHDGSNSDDNNNNNNNNNGKPY-YYIFKTKQDYQIDEKIQLKESKTYFQYKCLNDIK

-----GQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFT
      |   . | .      ..  |  |||..  .|  .   | .|  |  | | 
NYMYFKQFMRNQDDT-----KNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase CG17090.AA DYRK2 192-428 40 6.1e-90 292.66 In-house 1-241 (318) Show / Hide 
Range on Protein: 192-428
Range on HMM: 1-241/318
Sequence Identity: 40% (98 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADE-FNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLP
||.||..|.| |||||||    | . ||||.. |   ...| ..|. ||..... . |. .| |. .. |   ||.|..|| |  |||...|.|.|  . 
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLG
|. .|.   ..|..|  |..  .||.|||||||.|  . |    .|||||||   .      || |||.|||||.|||...  ||||||.||..|||. |
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRS--GIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTG

WPLYPGSSEFDQIRYISQTQGLPTEHMLNSA-----SKTSKFF
 || ||. |.||. ..    |.| ..... .     ...  ||
YPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFF
Kinase CG17090.AA DYRK1 192-520 39 3.2e-84 286.11 In-house 1-321 (321) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-321/321
Sequence Identity: 39% (131 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADE-FNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLP
||.   .|.| |||||| . . . | |||||.||  ..  | |||. .|  . .. ... .. |.  . | ..|| |||||.|  |||| |.  .|    
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LKYIRPILEQVLTALLKLK--QLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELF
|  .| . .|..|||| .    | .|| |||||||.|. | |    .|.|||||. .. . . . |.|||.||.||..||...  |||||||||.. |. 
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRS--AIKIIDFGSSCQLGQRIYQ-YIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMH

LGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKT
 | ||. ||.| ||.  |    |.| .||...| |. |.| .| | |   | .| |.... .   |.  .||       . |  .     | |  ..   
TGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNT---WYCKKTRDKKKH--YKEPCTRKLHEILGVETGGPGGRRKGEPGHSVE---

DRREFIDLLKRMLTIDQERRLTPAEALNHSFT
|   | ||.||||  | ..|.|| .|| ||| 
DYLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase CG17090.AA S_TKc 192-520 22 4.5e-80 273.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-231/231
Sequence Identity: 22% (79 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQ---NLYDFLKQNKF--
||.|. .|.|.||.| ||....| .||||||.|      .. . |..||..      .  | |. ...||. .| ..|.|....   .|.|..|...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--SPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCE-AIDMWSLGCV
  .|.|   .| .. |.. ||  . ..| || |||||||.| .      ..|..|||.| ..     .|.  ...|.|||..   ..   ..|.||.||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

VAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQL
..|.. | |..|   ..  .. |                                                                             
LYEMLCGYPPFP--QMQMMFKKIG----------------------------------------------------------------------------

LAEKTDRREFIDLLKRMLTIDQERRLTPAEALN-------HSFT
       .|..|.....|. | |.|.|  |||.       | . 
------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG17090.AA Pkinase 192-520 24 1.9e-58 205.29 Pfam 1-293 (293) Show / Hide 
Range on Protein: 192-520
Range on HMM: 1-293/293
Sequence Identity: 24% (88 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQI-----EVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQ-----NLYDFL
|.... .|.|.||.| || ..||..|||.||.| .     . |.     |..|. ||. .|      || ...|. |.| ..|.| .|       |.|..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN-----IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

K---QNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLV-DPVRQPYRVKVIDFGSAS---HVSKTVCNTYLQSRYYRAPEIIL-GLPFCE
.   ...|. .. . .. .. |.| .|  . . | || |||||||... ...  . .||..|||.|    . ... ..|.  ...|.|||.|. | .   
STWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

AIDMWSLGCVVAELFLGWPLYPGS----SEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDI
..||||.||...|...| |..||.    .  ||.  | .. | |..      .  | || |. . .                                  
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H----------------------------------

GQVNVPTDLEGGQLLAEKTDR--REFIDLLKRMLTIDQERRLTPAEALNHSFT
            . . .. ..  .|..|..|..|. | ..|.|....|.| . 
------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CG17090.AA PRP4 192-398 40 6.3e-54 185.48 In-house 1-209 (320) Show / Hide 
Range on Protein: 192-398
Range on HMM: 1-209/320
Sequence Identity: 40% (86 aa)

YEVLEFLGRGTFGQVVKCW-KRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQE---NADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQN-KF
|.|  . | | |. |..|  .  . | |||||. | ..  . |  |. || .|.       | |  || |. |.|..| ||||| .  || . ||.  | 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

SPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAE
  | || .|    | . ||  ||... .|||.|| ||.           | .|||||||..      ||.||.|||||||.| |.  .||||| ||  .|
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNE---SKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYE

LFLGWPLYPGSS
|. |  ..||..
LYTGKIMFPGKT
Kinase CG17090.AA CLK 192-328 32 5.1e-50 147.76 In-house 1-150 (350) Show / Hide 
Range on Protein: 192-328
Range on HMM: 1-150/350
Sequence Identity: 32% (49 aa)

YEVLEFLGRGTFGQVVKCWKRGTS-EIVAIKILKNHPSYARQGQIEVS-ILSRLSQE-NADEFNF---VRAFECFQH-KNHTCLVFEMLEQNLYDFLKQN
||..  || |||| ||.|| .  .   ||.|| .|.  |  . ..|.. |.  . .  ...  .    .. ...| . ..| |.|||..  ..|||.| |
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

K------FSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDP
.      . |.|.  || .  | ..|. .|  ..|.| ||||||| .||.
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDS
Kinase CG17090.AA DyrkP 192-390 37 5.7e-44 142.29 In-house 1-201 (323) Show / Hide 
Range on Protein: 192-390
Range on HMM: 1-201/323
Sequence Identity: 37% (76 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQE-NADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNK----F
| ..|.||   | . ..|  . |  .. .||. |   |  |   |. .|  .      || | .| .. | || |  .. |.|..|||.| | |.     
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

SPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAE
    .  .  |  |.| ||  .  | ||| |||||||..    .   .||.|||||.  .   .   | ||| |||||.|.|  .   ||||||||..||
RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKC--QVKIIDFGSSCFIHDHLS-SYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAE

LFLG
|. |
LWTG
Kinase CG17090.AA RCK 257-403 33 8.5e-33 101.18 In-house 64-223 (298) Show / Hide 
Range on Protein: 257-403
Range on HMM: 64-223/298
Sequence Identity: 33% (54 aa)

FECFQHKN--HTCLVFEMLEQNLYDFLKQ--NKFSPLPLKY--IRPILEQVLTALLKLKQLGLIHADLKPENIMLVD-----PVRQPYRVKVIDFGSASH
.| .....  .  .||| ...||| ..|    .  .|| .   |. |. |.| .|  .   |  | ||||||||. .       . ....|..|||.. .
KEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCRE

VSKTVCNT-YLQSRYYRAPEIILGL-PFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQI
.     .| |  .|.|||||..|      . .|.|..||. .||   .||.||||| |||
IRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQI
Kinase CG17090.AA CLK 335-396 42 1e-19 55.13 In-house 186-249 (350) Show / Hide 
Range on Protein: 335-396
Range on HMM: 186-249/350
Sequence Identity: 42% (27 aa)

VKVIDFGSAS--HVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPLYPG
..|||||||      ..   |  ..| |||||.||||.. .  | || ||.  || .|  |...
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQT
Kinase CG17090.AA RCK 192-226 45 1.4e-10 29.51 In-house 1-35 (298) Show / Hide 
Range on Protein: 192-226
Range on HMM: 1-35/298
Sequence Identity: 45% (16 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNH
| ... ||.||.| |.|  .  | |||||| .|..
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQK
Kinase CG17090.AA CLK 482-520 30 2.8e-08 20.19 In-house 312-350 (350) Show / Hide 
Range on Protein: 482-520
Range on HMM: 312-350/350
Sequence Identity: 30% (12 aa)

QLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFT
... .. . |...||...|| .|  .|.| ..|| | | 
YMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase CG17090.AA TyrKc 192-519 16 3e-08 -89.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 192-519
Range on HMM: 1-280/280
Sequence Identity: 16% (63 aa)

YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAF--E----------CFQHK------NHTCLVFEML
 . .. ||.| ||.|.|.  .   . ||.| ||..                  ..  .| .  . .  .          | |..         ..|.|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

EQ-NLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKT-VC----NTYL-----QSR----
.  .| |.|. ..   |..|    .  |.      | . ..|| ||   |... ..     .||. ||| .  .     .     .|      ...    
PHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

-YYRAPEIILGLPFCEAIDMWSLGCVVAELF-LGWPLYPG-----SSEFDQIRYISQTQGLPTEHM----LNSASKTSKFFYRDVDSTYPFWRLKTTEEH
    ||| |    | .. | || | .  |.| .| . |||      | .. |.|. |   .|  .                                   
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------

EAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSF
                                        .   |  .. |.    | | | | .|   . |
-------------------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase CG17090.AA DYRK2 487-520 35 4.6e-07 18.65 In-house 285-318 (318) Show / Hide 
Range on Protein: 487-520
Range on HMM: 285-318/318
Sequence Identity: 35% (12 aa)

KTDRREFIDLLKRMLTIDQERRLTPAEALNHSFT
... . ||| .|| .. | . |.||..||.| . 
GCEDENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase CG17090.AA DyrkP 487-520 44 2e-06 16.81 In-house 290-323 (323) Show / Hide 
Range on Protein: 487-520
Range on HMM: 290-323/323
Sequence Identity: 44% (15 aa)

KTDRREFIDLLKRMLTIDQERRLTPAEALNHSFT
.||   |||  ...| ||  || |  |||.| . 
RTDDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase CG17090.AA PRP4 495-520 46 2e-06 20.07 In-house 295-320 (320) Show / Hide 
Range on Protein: 495-520
Range on HMM: 295-320/320
Sequence Identity: 46% (12 aa)

DLLKRMLTIDQERRLTPAEALNHSFT
||| ..|  | ..| |. ||| |.| 
DLLDKCLMLDPKKRITCNEALKHPFI
Kinase CG17090.AA Pkinase_Tyr 192-226 33 9e-06 20.11 Pfam 1-39 (270) Show / Hide 
Range on Protein: 192-226
Range on HMM: 1-39/270
Sequence Identity: 33% (13 aa)

YEVLEFLGRGTFGQVVKCWKR----GTSEIVAIKILKNH
 . .. ||.| ||.|.|.  .    .|   ||.|.||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG
Kinase CG17090.AA RCK 492-520 34 2.7e-05 12.43 In-house 270-298 (298) Show / Hide 
Range on Protein: 492-520
Range on HMM: 270-298/298
Sequence Identity: 34% (10 aa)

EFIDLLKRMLTIDQERRLTPAEALNHSFT
. |.|.. ||..| . | |...||.| . 
DCIELMEKMLQWDPQKRITAQQALQHPYF