Gene Takl1 (Fruit Fly)

Takl1

Species: Fruit Fly
Alias: TAKL1, Takl1, Tak1-like 1, SFO162
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 92F5--8,

Classification

Group: TKL
Family: MLK
Subfamily: TAK1

Sequence

Name Sequence Type Origin Length Description Download
Takl1.NA RNA None 1182 None Fasta, JSON
Takl1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
Takl1.AA Protein Various 393 None Fasta, JSON

Protein domain

Protein domains of Takl1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Takl1.AA TAK1 11-265 48 2.1e-182 612.24 In-house 1-284 (284) Show / Hide 
Range on Protein: 11-265
Range on HMM: 1-284/284
Sequence Identity: 48% (137 aa)

KLSEKFLGAGSGGAVRKATFQNQEIAVKIFDFL----EETIKKNAEREITHLSEIDHENVIRVIGR-ASNGKKDYLLMEYLEEGSLHNYLYG-DDKWEYT
...|.|.|.|..|.|.||...|.|||||.|.|.    ||...||.||||...|..||.|.|...|. |.......|.|||...|||||.|.| ..|||||
IQNEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVDHPNIIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKPKWEYT

VEQAVRWALQCAKALAYLHSLD-RPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEA----------------------IKHL
...|..|..|||...|||||.. .|..|||||||||||.|.|..|||||||...||....|...||.|.||||.                      ....
HAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCDMHQMMTCNRGTCRWMAPEVRELFDFKSNRIIINQPTGFQKVFRCE

KYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKF
||..|||.||.||..||...|..||.|..||||.|.||.||..|...|||..|||||..|.|.|.||.|.||||||||.|..|.
KYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY
Kinase Takl1.AA MLK 11-266 32 2.1e-126 426.26 In-house 1-291 (291) Show / Hide 
Range on Protein: 11-266
Range on HMM: 1-291/291
Sequence Identity: 32% (95 aa)

KLSEKFLGAGSGGAVRKATFQNQE-----IAVKIFDF------LEETIKKNAEREITHLSEIDHEN-----VIRVIGRASNGKKDYLLMEYLEEGSLHNY
 . ....|.|| |.| |....|..     .|||....       ....... |.|. ||. ..|.|     .. . . ...... ...|||.|.|||.|.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYG-DDKWE-----------YTVEQAVRWALQCAKALAYLHSLDR-PIVHRDIKPQNMLLYN-----QHEDLKICDFGLATDMSNN---KTDMQGTLRYM
|.| ..||.           |....|..||||||....||||... ||.|||.|..|.|...     .|..|||||||...|....   .....||...|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEAI---KHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL
|||.|   .. ||. ||||.|.|..|||..||..||.     . ..... |.  ...  . ...|.|||..|.||..|.. .|.||||...| ..|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK-----QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase Takl1.AA TKL 17-266 25 2.5e-91 309.72 In-house 1-364 (364) Show / Hide 
Range on Protein: 17-266
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

LGAGSGGAVRKATFQN----------QEIAVKIFDFLE---------------------------ETIKKNAEREITHLSEIDHENVIRVIGRASNGKK-
.| |. | | |.....          ...|||.|   .                           . ...  |.|| ..| ..|.|... .| . .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------DYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLD------RPIVHRDIKPQNMLLYNQHE-------------D
             .. ||| . |||..||          .| .||||..|....|||| .      .||.|||.|..| |. .  .             .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

LKICDFGLATDMSNN----------------------KTDMQGTLRYMAPEAIKHL----------------KYTAKCDVYSFGIMLWELMTRQLPYSHL
.|||||||...||..                      .    ||.|.||||...                  .|. |||||||||.|||..||..||...
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

ENPNSQ------YAIMKAISSGEKLPME---------AVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL
 ..  .        .|.... |...|.             .|||...|.||..|.| .||||||..|| | |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Takl1.AA S_TKc 11-266 26 6.2e-64 219.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-266
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

KLSEKFLGAGSGGAVRKATFQN--QEIAVKIFDFLEETIKKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEE--GSLHNYLYGDDK--WE--
    . .| |. | |.|..  .  .. |.|| .       ....|||  |.. .|.|... ..   . .. |. |||..   |.|. |.    .  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

YTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKHLKYTA-KCDVYSFGIMLWELMT
..  .| ... | ..||.|.||.   |.|||.||.| || .    .||||||||. .    | . ||. ||||| .   .|.  |||..|.|..|.|...
FPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

RQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEK---------FL
.. |..       .....| |               ..  |.... |.. .|||||.  |. .         ..
GYPPFP------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Takl1.AA TKL-Unique 15-266 27 5.6e-61 208.9 In-house 3-290 (290) Show / Hide 
Range on Protein: 15-266
Range on HMM: 3-290/290
Sequence Identity: 27% (79 aa)

KFLGAGSGGAVRKATFQNQEIAVKIFDF---LEETIKKNAEREITHLSEID-HENVIRVIGRAS----NGKKDYLLMEYLEEGSLHNYLYG--------D
. .|.|. |.| |...   ..|.|.| .   .. ..... |.|.. .. .. |.|. . .|         .. .. |||...|||...|           
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

DKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQ----HEDLKICDFGLATDMSNN---KTDMQ---------GTLRYMAPEAIKH--
.. . . .| |. |...|... |||... || |||.|..| |. |         |||||||..  |..   .. .          |..|.|||| ..   
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF

LKYTAKCDVYSFGIMLWELMTRQL------PYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL
 .|. |.|||||||.|||. ||..      ||...    .|... ... . |.   . . ..||. .. |.. | . .|..|||  || . |
CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGM----DQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase Takl1.AA Pkinase 11-266 25 1.5e-60 212.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-266
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

KLSEKFLGAGSGGAVRKATFQNQE--IAVKIFDFLEETIKKN--AER--EITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEG----SLHNYLYGDDK
   .. .|.|| | |.|.. .. .   ||||..  .|  .|.  . |  ||  . ...|.|..| ..   .... |. |||.| |    .|. |. ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

WEY--TVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHED---LKICDFGLA----TDMSNNKTDMQGTLRYMAPEAIK-HLKYTAKCDVY
  .  . ... ....| ...|.|.||    |.|||.||.| |. |. .    .||||||||    .  .   |.  ||..||||| |. . .|. |.|..
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGIMLWELMTRQLPYSHL---ENPNSQYAIMKAISSGEKLPMEAVRSDCP-----------------EGIKQLMECCMDINPEKRPSMKEIEKF--L
|.|..|.|......|...    .| ..|..... | ...    .   .. .                 |  |.....| . .|.|||. ..| .   .
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Takl1.AA STE 12-261 19 1.4e-47 164.44 In-house 1-350 (359) Show / Hide 
Range on Protein: 12-261
Range on HMM: 1-350/359
Sequence Identity: 19% (69 aa)

LSE-KFLGAGSGGAVRKAT--------FQNQE---------IAVKIFDFLEE-----------------TIKKNAEREITHLSEID--HENVIRVIGRAS
.   ...| |..| | ||           ...         .|.|. .. ..                 ..... ..||  ... .  |.|... .|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NG-------KKDYLLMEYLEEGSLHNYLY---GDDK---------WEYTVEQAVRWALQCAKA-LAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFG
..        . .. |||.. |||   .    |  |         .    .|  . . |. |. |.||||.   |.||||||.| ||       |.||||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------VKLCDFG

LATDMSN-------------------NKTDMQGTLRYMAPEAIKH------LKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAI-------
... ...                   . . . ||  .|||| |.        .|..|||..|.|....|. | . |.. . ..   ..|.. .       
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

------SSGEKLPMEAV--------------RSDCPEGIKQLMECCMDINPEKRPSMKE
          .|| .                 . . .  |. .. | ...|.|||. ..
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Pkinase_Tyr Takl1.AA Pkinase_Tyr 10-266 30 1.7e-47 161.51 Pfam 1-270 (270) Show / Hide 
Range on Protein: 10-266
Range on HMM: 1-270/270
Sequence Identity: 30% (85 aa)

VKLSEKFLGAGSGGAVRKATFQ------NQEIAVKIF--DFLEET-IKKNAEREITHLSEI-DHENVIRVIGRAS-NGKK--DYLLMEYLEEGSLHNYLY
... .| ||.|. | |.|.|        ... |||.   .  .|  ...   ||.  .... .|.|..| .|  .  |.    |. ||| . |.|..|| 
ITFGKK-LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

GD--DKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDM-----S-NNKTDMQGTLRYMAPEAIKHLKYTAKCD
    ||   |... . ...| ||...||.|    ..|||.   | |. ...   |||||||| |.         ...     . ||||.|.. |.| | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSFGIMLWELMT-RQLP-YSHLENPNSQYAIMKAI-SSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL
|.|||. .||..|  . | |  . |      ....|  .|. .|.     .||. | .||  |.. .||.||...||  .|
VWSFGVLMWEIFTYGEQPTYPGMSNEE----VYEYIYEDGYRMPCPE---NCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc Takl1.AA TyrKc 10-266 27 2e-45 158.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-266
Range on HMM: 1-280/280
Sequence Identity: 27% (81 aa)

VKLSEKFLGAGSGGAVRKATFQNQEIAVKIFDFLEETIKKNAEREITHLSEI--DHENVIRVIGRASNG-------KKDYLLMEYLEEGSLHNYL-YGDD
..| .| || |  | |.|.|   .. |||     |.. ..   ||.  ....  .|.|..| .| .. .       .  ...||| . |.|..|| .  .
ITLGKK-LGEGAFGEVYKGTWK-IQVAVKM--LKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNN-------KTDM-----QGT----LRYMAPEAIKHLKY
|   .... . ...| |.  .||||   ...|||.   | |. ..|   ||.||||. |  .        .. .     .|     .| ||||.|.. |.
K--LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TAKCDVYSFGIMLWELMTR-QLPYSHLEN-PNSQYAIMKAISSGEKLPMEAV-----RSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL
| | ||.|||...||..|. | ||.  .  . | . ... . .|. .|  .         ||. . |.|..| . .||.||...|| ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Takl1.AA Ciliate-E2 11-262 18 1.4e-44 150.99 In-house 1-359 (365) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-359/365
Sequence Identity: 18% (73 aa)

KLSEKFLGAGSGGAVRKA-------------------------TFQNQEIAVKIFDFLEETIKKNAEREIT-------------HLSEIDHENVIRVIGR
    | .| |. | |.|.                          ......|.||.   .  ..|. ....               |....| |.|. .  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

AS--NGKKDYLLMEYLEEGSLHNYLYGDDKWE---------YTVEQAVRWALQCAK---------------ALAYLHSLDRPIVHRDIKPQNMLLYNQHE
    . .. || |||.. |.|  |..  .|..         .| ... .   | ..               || ||||  . |.||||||.| |.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

DLKICDFGLAT------------DMSNNKTDMQ-----------------------GTLRYMAPEAIKHLK---------YTAKCDVYSFGIMLWELMTR
 .||.||||..             ....... .                       ||. ||||| ..  |         |. |||..|.|..| |... 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

QLPYSHLENPNSQYAIMKAISSGEKLPME-AVRSDCPEGI--------------------KQLMEC----CMDINPEKRPS-MKEI
..|.                   ..  ..  .. .||| .                    |.|.      ... .||||.. ...|
KPPF-------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase Takl1.AA Dicty4 14-268 30 2.8e-44 145.69 In-house 4-277 (277) Show / Hide 
Range on Protein: 14-268
Range on HMM: 4-277/277
Sequence Identity: 30% (87 aa)

EKFLGAGSGGAVRKATFQNQEIAVKIF-----DFLEETIKKNAEREITHLSEIDHENVIRVIGRASN----GK-KDYLLMEYLEEGSLHNYLYG------
|...| || | | |.|   .| |||..     .| |....  . .|.. .. | | |..   | |..     . |    .||.  |.|.. |        
EQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFR-KEVHIMCKIRHPNICLFMG-ACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

-DDKWE-YTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLAT----DMSNNK--TDMQGTLRYMAPEAIKHLKYTAKCDV
  .| .  ....| | |. .|. ...||. .  |.|||.|. | ||  ..   |.|||||..    . ...   . . ||  .||||   |  |. | ||
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHN-LLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSFGIMLWELMTRQLPYS-HLENPNSQYAIMKAISS-GEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKF--LGE
|||||.|||. ||| ||. |  ..     .  |. . ....|. .   .||  .|.|.. | | .|..|||..|| .   | .
YSFGIVLWEILTRQEPYQKHHMPY---MQFVRAVCNKKLRPPIPD---WCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase Takl1.AA CAMK 16-266 18 1.5e-43 137.72 In-house 1-425 (425) Show / Hide 
Range on Protein: 16-266
Range on HMM: 1-425/425
Sequence Identity: 18% (78 aa)

FLGAGSGGAVRKATFQ-N-------------QEIAVKI-------------------FDFL---------EETIKKNAEREITHLSE-------IDHENV
 || || | |....   .             |. |.||                    |.          ..  .|| .|||  ..        .||.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRVIG---------------RASN-----GKKDYLLM---EYLEEG----SLHNYLYGDDK-------------WEYTVEQAVRWALQCAKALAYLHSLD
|. .                  |.      |. |. |   || . |     | .|.    .               .| ..| |.  | . |..|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

RPIVHRDIKPQNMLLYNQH----------------EDLKICDFGLATDMSNN--------------------------KTDMQGTLRYMA-PEAIKH---
  |||||.|| | || . .                 ..||.|||.|. .  .                           ... ||. ||| || ..    
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-----------LKYTAKCDVYSFGIMLWELMTRQLPYSHLENPN---------SQYAIMKAISSGEKLPMEAVRSD--------------------CPEG
             |. |||. | |..|  . .  .|. .  . .         ..| ... | .|.    .   |.                    . . 
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

IKQLMECCMDINPEKRPSMKEIEK--FL
 |.|  ...  .||||.. ... .  ..
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Takl1.AA TK 10-266 16 1.1e-42 140.39 In-house 1-486 (486) Show / Hide 
Range on Protein: 10-266
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

VKLSEKFLGAGSGG---AVRKATFQN---------------------------QEIAVKIFDFLEETIKKNAER-----------------EITHLSE--
..| .| ||.|  |    |.|.. ..                           .. |||.     .. ..  .                  |.  ...  
ITLGKK-LGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSL

IDHENVIRVIGRASNGKKD------------YLLMEYLEEGS----LHNYLY--G---------------------------------------------
 .|.|..| .|  . |.              ...||| . |.    |..||                                                 
GHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

-------DDKWEYTVEQAVR-------------------WALQCAKALAYLHSLDR----PIVHRDIKPQNMLLYNQHED----------LKICDFG---
       |.  . |  . ..                   ...| |....||||.       .||||.   | |. ... .           ||.|||   
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LATDMSNN----KTDMQGT-------------------------LRYMAPEAIK---------HLKYTAKCDVYSFGIMLWELMT--RQLPYSHL
     || |. ..    ... .||                         .|.||||...         . |.| | ||.|||...||..|  .. .|  .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

EN------PNSQYAIMKAISSGEKL----------PMEAVR-SDCP--------------EGIKQLMECCMDINPEKRPSMKEIEKFL
 |        .   .|. . .| .|           |.  .  .||              | . .|| .| . .||.||..... ..|
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Takl1.AA LRRK 112-268 32 4.8e-36 125.01 In-house 170-351 (351) Show / Hide 
Range on Protein: 112-268
Range on HMM: 170-351/351
Sequence Identity: 32% (60 aa)

ALQCAKALAYLHSLDRPIVHRDIKPQNMLL-----------YNQHEDLKICDFGLAT----DMSNNKTDMQGTLRYMAPEAIK---HLKYTAKCDVYSFG
||| ||...|||| . ||.||| |. | ||            |.|   ||.|||. .    . .    .. |. ..|||| ..      || | |.||||
ALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFG

IMLWELMTRQ-LPYSHLE-NPNS--QYAIMKAISSGEKLPMEAVRSD-CPE-----GIKQLMECCMDINPEKRPSMKEIEKFLGE
. ||||.||| .|. ...    .  .. | ..|..| .     . .. ||.       ..|.. | . .|.|||.. .| |.|..
MILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLR---PTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase Takl1.AA LRRK 11-71 12 0.00097 9.09 In-house 1-124 (351) Show / Hide 
Range on Protein: 11-71
Range on HMM: 1-124/351
Sequence Identity: 12% (16 aa)

KLSEKFLGAGSGG-AVRKATFQN----------------------------QEIAVKIFDF--------------------------------LEETIKK
  .|. .| |. |  | .|....                            |..|.|....                                .|.....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

NAE--REITHLSEIDHENVIRVIG
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FREFRHEVWIMSHLNHPNIVSLKG