Gene CG1227 (Fruit Fly)

CG1227

Species: Fruit Fly
Alias: CG1227, SFO135, MPSK/PSK
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 84D3,

Classification

Group: Other
Family: NAK
Subfamily: MPSK

Sequence

Name Sequence Type Origin Length Description Download
CG1227.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 274 Kinase domain by global Sugen HMM Fasta, JSON
CG1227.AA Protein Various 320 None Fasta, JSON

Protein domain

Protein domains of CG1227.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG1227.AA MPSK 30-309 62 8.10000000001e-231 773.1 In-house 1-281 (281) Show / Hide 
Range on Protein: 30-309
Range on HMM: 1-281/281
Sequence Identity: 62% (175 aa)

YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDY-ELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLR
|....||..||||..||.||......||.|||.||...|||.|.||.|.....|..|.||.||. .|||..||||||......||||.|||.|.||||..
YYFMQRLGEGGFSYVDLVENLHDGHFYALKRIQCHEQQDQNQAQREAEMHCQFDHPNIIRLVDWGCLKGREDIVINTKHEIWLVLPYFKHGTLWDHLQRM

SRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTYC
..|.|.|.|.||..|||||||||||||||||.|.||||.|..||||.|.|.|.|.|||||.||..|..||..|..|||.|.||.|.||||||||.|...|
KDKGDCMTEDQIWWIFLGVCEGLKAIHEAMPKPYAHRDMKPTNICLGDDFQPVIMDLGSMNEACIQVKGQRQACALQDWAAERCSMVYRAPELFHVQSHC

TIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERT
.||||||||||||||||||||.||||.||.|||||.|||...|.||||.|.|..|||.||.||.|.||||||..| |  .|
VIDERTDIWSLGCVLYAMCYFHSPYDMIYQRGDSVHLAVQNRNFNIPENSRYSQDMHQLISYMMRVDPMERPHIFWVLNQT
Kinase CG1227.AA NAK 30-309 37 3.5e-150 504.61 In-house 1-299 (299) Show / Hide 
Range on Protein: 30-309
Range on HMM: 1-299/299
Sequence Identity: 37% (114 aa)

YTIRERLATGGFSLIDLGENA---------STRRSYAIKRITCHS-IDDQNIALREIENCRKIDSENVIRVVDY-ELKGQADIVINTTSTLFIVLPYYKH
||....||.|||| ..| ...         |....||.||..|||  .|.|.. ||||...|....|.|. ... ......|.  |.|.. |....|..|
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDS--NGTWEVFLLMEYCCH

GSLADHLQLRS-RKQDHMPEAQILQIFLGVCEGLKAIHEAM-PVPLAHRDLKTANICLSD---SFEPIIVDLGSMTEARLQIVGQTDAQR---LQDEAEE
|||.|... |  .|.....|..|||||..||||..|.|... |.|..|||.|  ||.||.   ...... |.||||.|..|. ....||.   .||....
GSLWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINK

RSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSG--NINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIER
. ...|||||.. .. .|.|||..|||.|||.||.||....|....|.|.||..||...|  ...||..| |...||.||.|||..||..||... |...
YTTPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQ

T
.
L
Kinase CG1227.AA NAK-Unclassified 30-311 22 7.5e-64 218.45 In-house 1-405 (405) Show / Hide 
Range on Protein: 30-311
Range on HMM: 1-405/405
Sequence Identity: 22% (92 aa)

YTIRERLATGGFSLIDLGE---------N-----ASTRRSYAIKRITCHSIDDQNIALREIENCRKID-SENVIRVVDYELKGQADIVINTTSTLFIVLP
|||   || |||| . |           |      |.   |. ||. | . .  | . |||.. ..   ..|..   |.      . .. .  . |....
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSY--EVFMLME

YYKHGSLADHLQ------LRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMP-------------------------------------------VPLAHR
|.. ||| |  .       |  .|    |. .|||...||.|. . |   |                                           .||.||
YCSRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHR

DLKTANICLS---------------------------------------------------------DSF-EPIIVDLGSMTEARLQIVGQTDAQRLQDE
|.|  |. ..                                                         ..  .... |.|| .|..  |   ...| |||.
DIKIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQEMQYLQDW

AEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERG-DSVALAVLS--GNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFS
 .      |||||..  .  | |||. |||.||| || ||....| .   . .  ||....|.  |.  .|  . | .. | ||| ||  || .|| .. 
INMHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQ

VIERTHD
|...   
VLNHICQ
Kinase CG1227.AA BIKE 31-308 30 1.2e-39 138.04 In-house 2-267 (267) Show / Hide 
Range on Protein: 31-308
Range on HMM: 2-267/267
Sequence Identity: 30% (87 aa)

TIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRK-IDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRS
|. | || |||... |  . .  . .|.||       | |.. ||..  .. .   |..  ||      .. |        |  .| .|  . . .  | 
TVEEQLAEGGFAMVFLVRDHKGNK-CALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWE----CMILMEYCRH-QVVNMMNQRL

RKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSF--EPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTY
.. ... |  .||||  |||    .|.  . |  |||||  || |.|.   . .  | || | .... . .   .  .|| |    . |||||.      
QQGQYFTEQEVLQIFCDVCEAVSRLHH-CQTPIIHRDLKVENILLHDHGPPHYVLCDFGSAT-NKFLNPQKHGVNYVKDEIEKYTTMCYRAPEMIDLYSG

CTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIER
 .|  . ||| ||| || .|.|  |.      | |  ||. .||  ||. | | ..|| ||.|||  |.  || .. | . 
KEITTKADIWALGCMLYKLCFFCLPF------GES-QLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDIYQVSHV
Kinase CG1227.AA Pkinase 30-300 17 5.1e-36 128.45 Pfam 1-282 (293) Show / Hide 
Range on Protein: 30-300
Range on HMM: 1-282/293
Sequence Identity: 17% (54 aa)

YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDD--QNIALR--EIENCRKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHG----SL
|.| ...  |.|.   .. . .|.. .|.|.|  .....  . ...|  ||.  ......|..|  |.             . . .|..|  .|    .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---------KDHIYMVMEYCEGGLYVMDL

ADHLQLRSRKQDHM--PEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEP----IIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIV
.|...   ...  .  .| ..  ... ...||. .|.       ||||| .|| ...  ..     | | |.   ..          . .       .. 
FDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPW

YRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYD-P----IYERGDSVALAVLSGNINIPEDSIYT-------------------EDMHELIKYM
|.|||.  ....  .. . |.||.||.|| |.  . |..         . . .   .... .  ...  ..                   |.. ..||..
YMAPEV--IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

LRTDPMERP
|. || .||
LCKDPKKRP
Kinase CG1227.AA S_TKc 30-313 20 1.1e-32 115.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-313
Range on HMM: 1-231/231
Sequence Identity: 20% (61 aa)

YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKH--GSLADHLQL
|.| . .  |.|.   .. . .| | .|||.|        . ..|||. ..| . .|...  |.             . |..|. |  .  |.| |... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD----------DHLYMVMEYCDGDLGDLFDYIKK

RSRKQDH--MPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVK
| |.  .  .|| ..  ..  .|..|. .|.       ||||| .|| |..  .  | | |. ..                      .  |.|||..   
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL---

TYCTIDE-RTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERT-----HDLI
     .  . |.||.||.|| |..   |..          ....  .|        .... ..|. .|. || .|| .  . ..      |  .
---GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG1227.AA Ciliate-E2 30-300 16 2e-29 98.15 In-house 1-353 (365) Show / Hide 
Range on Protein: 30-300
Range on HMM: 1-353/365
Sequence Identity: 16% (62 aa)

YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHS---------------------------IDDQNIALREIE----------NCRKIDSENVIRVVD
| . . . .|.|. . .... .... .|||.|. .                            |   .  .|||.          ....... |.|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YELKGQADIVIN-TTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPE-------AQILQIFLGVCE---------------GLKAIHEAMPVPLAHRDLKT
.         .. .......|. |...|.| |... .. |..| .|        .|..|.  ...               .|. .|.  .    |||.| 
C--------FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKP

ANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERS------------------------SIVYRAPELFTVKTYCT------IDERTDIWSL
 || .     . |.|.|  ...  .   .|.  ... .  . .                        .  | ||| .  | | .       |.  |||||
ENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL

GCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIP----------------EDSIYTEDMHELIKY----MLRTDPMERP
|..|| |.. . |.              . ..|..|                .    ....  |||     ||  || .|.
GVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI
Kinase CG1227.AA Ciliate-E2-Unclassified 30-300 17 1.3e-21 71.78 In-house 1-341 (352) Show / Hide 
Range on Protein: 30-300
Range on HMM: 1-341/352
Sequence Identity: 17% (61 aa)

YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALR--------EIENCRK---------------IDSENVIRVVDYELKGQADIVINTT
|.| . . .|||. . . .. ..   ||.| .  . |..|.. ..        ...|..|               ... . ..|....       . ...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFY-------CFQDK

STLFIVLPYYKHGSLADHLQLRSR------------KQDH-MPEAQIL-----QIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDS---FEPIIVDL
 ...||. | ..|.| .... |.             ||..  .| |..     ..|  ...||. .|.       |||.|  || ....   ... | |.
QNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN--NIIHRDIKPENILFDNNGKNYYIKIIDF

GSMTEARLQIVGQTDAQ-----RL-QDEAEERS-SIVYR----APELFTVKTYCTID-ERTDIWSLGCVLYAMCYFNSPYDPIYERGDS-----------
|.  .   ..  . . |     .. |...  .. .. |     |||..  . | .   .  ||||||..||.|.. . |..   .  .            
GISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAY

---VALAVLSGNINIPEDS------IYTEDMHELIK----YMLRTDPMERP
   .    . .||..|. .      .  .   ..|.     ||  .| .|.
RKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI
Kinase CG1227.AA TKL 36-300 15 7.8e-21 71.76 In-house 1-355 (364) Show / Hide 
Range on Protein: 36-300
Range on HMM: 1-355/364
Sequence Identity: 15% (55 aa)

LATGGFSLIDLGENASTR--------RSYAIKRITCHSID---------------------------DQNIALREIENCRKIDSENVIRVVDYELKGQAD
.  |||. .  |.   ..        .  |.|..  |. |                            .    .||  ..... .|... . | . .. .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-IVIN---TTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMP-----VPLAHRDLKTANICLSDSFE------------
 ....   ... |.||  |...||| ..|.            |.... |... |.   |   |      |..|||||..|| . . ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PIIVDLGSMTEARLQIVGQTDAQRLQ------DEAEERSSIV----YRAPELFTVKTY-------------CTIDERTDIWSLGCVLYAMCYFNSPYD
  . | |.|  ..       .  .   .      . .. .....    . |||..  ...              . .|..|..| | ||. ..    ||.
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

PIYERGDSVA-------LAVLSGNINIPED------------SIYTEDMHELIKYMLRTDPMERP
 . ..   ..         | . .   | .            .   ..| .|..    .|| .||
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP
Kinase CG1227.AA TKL-ciliate1 131-309 18 1.2e-20 67.4 In-house 94-279 (279) Show / Hide 
Range on Protein: 131-309
Range on HMM: 94-279/279
Sequence Identity: 18% (36 aa)

KQ--DHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFT--VKT
..    ... ... .   .  |.  .|   . || |||||  || ..  ... | . .... |    .   . | .| | .      ..||| .   .  
HSQIYMIKWQHRMRWCKDIAQGMQYLHMRQN-PLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFP

YCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDS------------IYTEDMHELIKYMLRTDPMERPFVFSVIERT
   | |. ||...| |.| .|    |.. .        . |...  ...|              .. . .|.|.. ..  .|  ||    .|.. 
NYPINEKIDIYAYGIVMYILCFRKTPFQQK--------MSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase CG1227.AA STE 30-172 18 4.7e-13 42.54 In-house 1-183 (359) Show / Hide 
Range on Protein: 30-172
Range on HMM: 1-183/359
Sequence Identity: 18% (36 aa)

YTIRERLATGGFSLIDLGENA------STRRS---------YAIKRITCHSI-----------------DDQNIALREIENCRKID--SENVIRVVDYEL
... |..  |.|    .. |       .| .          .|||..   .                  ....  |.||. ..| .  ..|...  ....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KGQADIVINTTS--TLFIVLPYYKHGSLADHLQ-LRSRKQ---------DHMPEAQILQIFLGVCEG-LKAIHEAMPVPLAHRDLKTANI
|.  .    . .  .|.|.. |   ||| | ..   ....         ...|| ||  |   ...| |. .|.       |||.| |||
KEGHN----HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANI
Kinase CG1227.AA NEK 231-308 33 3e-10 32.71 In-house 202-283 (286) Show / Hide 
Range on Protein: 231-308
Range on HMM: 202-283/286
Sequence Identity: 33% (28 aa)

DERTDIWSLGCVLYAMCYFNS--PYDP-IYERGDSVALAVLSG-NIN-IPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIER
... |||||||||| || . .  | .  .     | .. .  | . . ||.  .| .|...||  ||. || .|| . ...|.
NNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEM
Kinase CG1227.AA TyrKc 30-313 19 1.8e-08 -85.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-313
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

YTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKI--DSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQL
 |  . |  | |  . .|.     .  |.| .  ..   .   .||..  .|.  . .|..| . . ....          |.||. | .||.| |.|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRK

RSRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQ-IVGQTDAQRLQDEAE---ER--SSIVYRAPEL
. .|    . .. |.. . ...|   .|.    .. |||| . |. ... .   | | | . .       |   ..   . .|   ..    |   ||| 
HRPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPEC

FTVKTYCTIDERTDIWSLGCVLYAMCYF-NSPYDPIYE---RGDSVALAVLSGNINIPEDS-------IYTEDMHELIKYMLRTDPMERPFVFSVIERTH
.    |..  . .|.|| | ... .. .  .||  . .     . |   | .|.   . ..       . ...|....|   . || .||  || |   |
I---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSEI---H

DLI
...
ECF
Kinase CG1227.AA NEK 101-172 27 9.2e-08 23.83 In-house 73-150 (286) Show / Hide 
Range on Protein: 101-172
Range on HMM: 73-150/286
Sequence Identity: 27% (22 aa)

IVINTTSTLFIVLPYYK-HGSLADH---LQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLA---HRDLKTANI
.. .  ..|.||  |    | |...   .. .  | ....| ||. .|   | .|| .|.    |     |||.|..||
FIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GPQRKILHRDIKPQNI
Kinase CG1227.AA STE 231-300 17 2.3e-05 15.01 In-house 246-346 (359) Show / Hide 
Range on Protein: 231-300
Range on HMM: 246-346/359
Sequence Identity: 17% (18 aa)

DERTDIWSLGCVLYAMCYFNSPY---DPIYERGDSVAL-AVLS----------GNINIPED-----------------SIYTEDMHELIKYMLRTDPMER
|.. |||||||..  |.  . |.    | .         .. .          .   .|..                 . ....... |.  |. || .|
DTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR

P
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P