Gene CG3277 (Fruit Fly)

CG3277

Species: Fruit Fly
Alias: SFO206, CG3277
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 23E3,

Classification

Group: TK
Family: VEGFR

Sequence

Name Sequence Type Origin Length Description Download
CG3277.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON
CG3277.AA Protein Various 757 None Fasta, JSON

Protein domain

Protein domains of CG3277.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase_Tyr CG3277.AA Pkinase_Tyr 373-731 28 8.99999999999e-122 413.04 Pfam 1-270 (270) Show / Hide 
Range on Protein: 373-731
Range on HMM: 1-270/270
Sequence Identity: 28% (105 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADE--VAEYLAEIEMLKGVGTHHNVVSFLGCCT-IKPP--YLMIMEYVNKGNLLSYLR
|..|..|||||||.|...|.       ... |||| ||..   ..   .. ..|....|  | |.|.|...|.||  . |  ....|||. .|.||.|||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

TVRKEASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAESKLVALGLTSWAKSVNENLISATYTIVE
. |                                                                                                 
KHR-------------------------------------------------------------------------------------------------

DEDAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHG----IY-TNTRTRKLPLRWLSIEAIRENVYSSKSDIWA
     .  |. |.| ....|||.|| .||.. . ||||||||.|...|.. ||.||||.|       | . .   ||| .|.. |.|.......|||.|.
---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YGVVLWEIGTLGASP-YPTISNDELIPFL-MAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
.||..||| |.|..| || .|| |.. ..   |.|...|| |.. .|..|.||| ..||.|||| ...  |
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc CG3277.AA TyrKc 373-731 27 2.4e-121 410.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 373-731
Range on HMM: 1-280/280
Sequence Identity: 27% (108 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVG-THHNVVSFLGCCTIK-------PPYLMIMEYVNKGNLLS
|. |..|||||||.|...|..        . |||| ||..     ... . |..... .|  | |.| ..|.|| .       .|....|||. .|.|..
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YLRTVRKEASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAESKLVALGLTSWAKSVNENLISATYT
|||  |..                                                                                            
YLRKHRPK--------------------------------------------------------------------------------------------

IVEDEDAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHG----------IYTNTRT---RK--LPLRWLSIEAI
           | .|.|..|..|||.||..|... . ||||||||.|...|.| ||||||||| .           |  ...   .|  ||.||...|.|
-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

RENVYSSKSDIWAYGVVLWEIGTLGASPYPT-----ISNDELIPFLMAGNRLERPEI--------CTPQVYTIMLQCWLEEPEERPTFDALYKVL
.......|||.|..||..||| |.|..|||      .||.|.| ....|.|...|.         |.. .|.||.||| |.||.|||| .... .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CG3277.AA VEGFR 566-731 44 1.1e-116 393.91 In-house 156-332 (332) Show / Hide 
Range on Protein: 566-731
Range on HMM: 156-332/332
Sequence Identity: 44% (79 aa)

VEDEDAFEY----ILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHGIYTN----TRTR--KLPLRWLSIEAIRENVYS
|| ...||.    .|....|.....|.|.||.||......||||||||.|...|...||.||||.|||||..    ....  .||..|...|.|...||.
VEPDEVFEDMWKDPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYT

SKSDIWAYGVVLWEIGTLGASPYPTIS-NDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
..||.|.|||.||||..||.||||... ..|....|..|.|...|..|||..|.|||.||..||||||.|..|...|
TYSDVWSYGVFLWEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase CG3277.AA TK 373-731 17 3.2e-109 367.41 In-house 1-486 (486) Show / Hide 
Range on Protein: 373-731
Range on HMM: 1-486/486
Sequence Identity: 17% (103 aa)

IQIGRMLGEGAFG---QVHEATAINLRRMRGT--------------------TIVAVKQLKPNPKADEVAEYL----------------AEIEMLKG-VG
|..|. ||||.||   .|.......... .|.                    | ||||.||.   ... .. .                .|..|..  .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

THHNVVSFLGCCTIK------------PPYLMIMEYVNKGN----LLSYLRTVRKEASK------------------LRNRNANYTSCRPIMTRTNSTSS
 | |.|...|.|| .            .|....|||...|.    |..|||. |.....                  ..                     
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHC---------------------

PKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAESKLVALGLTSWAKSVNENLISATYTIVEDEDAFEY------------------------
                                                                         .                          
-------------------------------------------------------------------------M-KGDITYSHESNSPCPEEQDYDDDLI

-------------------------ILDNKELHNFALQIANGMRFLEEQ------EITHRDLAARNVLIDSNKT-----------LKISDFGLSR-----
                         .|. ..|. ...|||.||..|...       . ||||||||.|...|..            ||.||||||     
KDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGV

-------HGIYTNTR------------------------TRKLPLRWLSIEAIRENV---------YSSKSDIWAYGVVLWEIGTLG-ASPYPTISN---
       .. |. ..                         .|||.||.. |.....|         ...|||.|..||..||| |.| . .|. .||   
LARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDV

------DELIPFLMAG--------------NRLERPEICT--------------PQVYTIMLQCWLEEPEERPTFDALYKVL
      .|.. .| .|              .|...|. |.              . .| .|.||| ..||.||||..|.. |
WKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CG3277.AA TK-Unique 373-731 29 6.5e-106 358.17 In-house 1-294 (294) Show / Hide 
Range on Protein: 373-731
Range on HMM: 1-294/294
Sequence Identity: 29% (110 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTT-IVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKP-PYLMIMEYVNKGNLLSYLRTVR
. .|. .||||||||. ... ..   .. . .||||.|| |    .....| ||.|.| .| | |.|..||||| .  | ..||||. .|||..|||| |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

KEASKL------RNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAESKLVALGLTSWAKSVNENLISATYT
....        .                                                                                      .
PAMRQHQTYGNLK------------------------------------------------------------------------------------FDF

IVEDEDAFEYILDNKELHNFALQIANGMRFLEE--QEITHRDLAARNVLIDSNKTLKISDFGLSR----HGIYTNTRT-RKLPLRWLSIEAIR--ENVY-
 .. .. ... .. | | .|| |||.|| .|..  ..|.||||.|||||. ..|..||.|||..|    .| | ....  ..|.||.. |...  ...| 
HHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYH

SSKSDIWAYGVVLWEIGTLGASPYPTISNDELIPFLMAGNRLERPEIC-TPQVYTIMLQCWLEEPEERPTFDALYKVL
..|||.|..||..||| |||| ||| .......  . .| |...|| | ....| .| .|| .||||||.|... ..|
TTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase CG3277.AA KIN6 575-731 36 4.3e-68 224.06 In-house 140-305 (305) Show / Hide 
Range on Protein: 575-731
Range on HMM: 140-305/305
Sequence Identity: 36% (61 aa)

ILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNK---TLKISDFGLSR----HGIYTNTRTRK-LPLRWLSIEAIRENVYSSKSDIWAYGVV
..  |.| .|| ||..||..|    . ||||||||||...     | ||||||| |         ...  . ||..|.. |...   .| |||.| .||.
CIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVL

LWEIGTLGASPYPTIS-NDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
..|. .|| .|||..    |.|... .| |.. |. |. ..| || .|| | |..|| |. . . .
MFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF
Kinase CG3277.AA UTK 570-731 32 2e-67 229.75 In-house 109-296 (296) Show / Hide 
Range on Protein: 570-731
Range on HMM: 109-296/296
Sequence Identity: 32% (62 aa)

DAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSN-------KTLKISDFG---LSRHGI------------YTNTR-TRKLPLRWLSI
.|.. .|.. ..  .|..||.|| .|... . ||||||||.|....        . ||.|||   .||               | . .  ...|.|| . 
PACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAP

EAIREN-VYSSKSDIWAYGVVLWEIGTLGASPYPTISNDELIPFLMAG--NRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
||. ..  ...|||.|..|||.||| | |. ||| .||.... ....|   |...|. |  .||..|..||  .|.|||.|. |....
EALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase CG3277.AA VEGFR 373-472 50 1.1e-65 224.47 In-house 1-103 (332) Show / Hide 
Range on Protein: 373-472
Range on HMM: 1-103/332
Sequence Identity: 50% (52 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTI---KPPYLMIMEYVNKGNLLSYLRTV
...|.|||.|||||||||.|...|.|...|.||||.||....|.|......|..||...|.|.|||.||||||.   |.|...|.||...|||..|||| 
LKLGKMLGRGAFGQVHEASAFGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK

RKE
|..
RMY
Kinase CG3277.AA RTKB 576-731 40 2.2e-63 212.5 In-house 106-264 (264) Show / Hide 
Range on Protein: 576-731
Range on HMM: 106-264/264
Sequence Identity: 40% (65 aa)

LDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSR---HGIYTNTRTRKLPLRWLSIEAIRENVYSSKS-DIWAYGVVLWEIG
|  . |  |..|||.|| ||. ... ||||.|||||.|.. . ||.|||..|   |. |. | || || .|. .| . .  |..|| |.|..||  ||| 
LKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTR-LPIKWMAPESWAHRIYTTKSGDVWSFGVTMWEIF

TLGASPYPTISNDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
.||. ||.. .| .. ..|  | ||. |.   .... || .|| .|...||.||.| . .
SLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase CG3277.AA FGFR 567-731 44 2.8e-62 211.07 In-house 122-293 (293) Show / Hide 
Range on Protein: 567-731
Range on HMM: 122-293/293
Sequence Identity: 44% (77 aa)

EDEDAFEYI--LDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSR--HGI--YTNTRTRKLPLRWLSIEAIRENVYSSKSDI
|..|  | |  | .|.|  .| |.| || .|. . . ||||||||||.  .  .||.||||.|  | |  |  |    ||  |   ||  ..|| ..||.
EQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRLPIKWMAPEALFDRVYTHQSDV

WAYGVVLWEIGTLGASPYPTIS-NDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVL
| ||| |||| |.| .|||.|    ||  .|. | |.|.|. |.  .| .| ||| ..|..||||  |   |
WSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase CG3277.AA Src 584-731 42 2.1e-61 207.37 In-house 102-255 (255) Show / Hide 
Range on Protein: 584-731
Range on HMM: 102-255/255
Sequence Identity: 42% (65 aa)

FALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSR---HG--IYTNTRTRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLGASPY
.| |.|.|| .||.. . ||||||||||.. |   |. |||| |   ..  .|.     |.| .|   |||...... ||| | .|. |.|| | |  ||
MAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPY

PTISNDELIPFLMAGNRLERPEICTPQVYT-IMLQCWLEEPEERPTFDALYKVL
|  .| | .  ...| |. .|. | ...|  |||||| ..||.||||. |...|
PGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase CG3277.AA Fer 579-732 34 4e-61 206.9 In-house 111-283 (283) Show / Hide 
Range on Protein: 579-732
Range on HMM: 111-283/283
Sequence Identity: 34% (60 aa)

KELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLK---ISDFGLSRHG---IYTNT---RTRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWE
.|......|.|.||..|... . |||.||||.|.. .|. |   |||||.||..   .|. .     .|.| |||. |...  .||.|.|.|..||..||
NEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWE

IGTLGASPYPT----ISNDEL----IPF-LMAGNRLERPEICTPQVYTIML-QCWLEEPEERPTFDALYKVLS
| | || |||.    . . ..    .     .|...  |. . | .. ||. ||| ..||.|||.. ... | 
IFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase CG3277.AA Ret 579-733 44 5.8e-54 182.68 In-house 135-293 (293) Show / Hide 
Range on Protein: 579-733
Range on HMM: 135-293/293
Sequence Identity: 44% (70 aa)

KELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSR----HGIYTNTRTRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLG
|..  || ||  || .| |  . ||||||||||.   . .|||||||.|     . |      ..|  |  ||.   .|| .|||.| .|| .||| |.|
KMIISFAWQICKGMHYLSEMKLVHRDLAARNVLVAEGRICKISDFGLTRDVYEDDSYVKRSKDRIPVKWMAIESLYDHVYTTKSDVWSFGVLCWEIVTMG

ASPYPTISNDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYKVLSP
|.||| |  . |   |  | | .||| |   .| ||.||| .||. || |  . | .  
ANPYPGIPPERLWQLLKTGYRMDRPENCSEEMYRIMRQCWKQEPDKRPVFKFISKDFEK
Kinase CG3277.AA Pkinase 373-731 17 7.4e-33 117.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 373-731
Range on HMM: 1-293/293
Sequence Identity: 17% (71 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLA----EIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKG----NLLS
..||| .|.|.||.| ... .. ..     |||||..|   ....  .. .    ||...| .  | |.| ...... |. . |.|||...|     | .
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

YLRTVRKEASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAESKLVALGLTSWAKSVNENLISATYT
|..|                                                                                                
YIST------------------------------------------------------------------------------------------------

IVEDEDAFEYIL--DNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTL----KISDFGLSR---HGIYTNTRTRKLPLRWLSIEAIR-ENVY
        .  .  . .|. ....||. |. .. .. | ||||   |.|||.| ..    ||.||||..   .  .. . |.   ..... | ||  . |
------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

SSKSDIWAYGVVLWEIGTLGASPYPTI----SNDELIPFLMAGN---RLERPEICT-------------------PQVYTIMLQCWLEEPEERPTFDALY
..|.|.|..|..|.|  . |  |.|      ..|..  . . .    . ..|. |.                   .    ..  |.   |..|||.. . 
GPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

KV--L
.   .
QHPWF
Kinase CG3277.AA FGFR 373-488 37 3.8e-29 96.44 In-house 1-118 (293) Show / Hide 
Range on Protein: 373-488
Range on HMM: 1-118/293
Sequence Identity: 37% (44 aa)

IQIGRMLGEGAFGQVHEATAINLRRM--RGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVR
  .| |||||.||||  |.|. . .     ...|||| || |   .. .    |.||.| .| | |..  |||||   |   | ||  .|||  .||  |
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

KEASKLRNRNANYTSCRP
  . . .    .||  .|
PPGMDYKKDSQEYTDYKP
Kinase CG3277.AA Ret 373-471 40 3.9e-22 72.37 In-house 1-101 (293) Show / Hide 
Range on Protein: 373-471
Range on HMM: 1-101/293
Sequence Identity: 40% (41 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPN-PKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKP--PYLMIMEYVNKGNLLSYLRTV
 | .  |||| ||||  |.|. .|   | | |||| || |     |    | | ..|| |  | .|.  .| |. .   | ..| ||   | | ..||  
LQLDDTLGEGHFGQVVKAQAFHIRGHPGYTTVAVKMLKRNTANSSEYHDLLSEFQLLKQV-NHPHVIKLYGACIQDDPFPTCLIVEYCKYGCLREFLRLS

RK
||
RK
Kinase CG3277.AA UTK 373-473 33 4.6e-22 72.29 In-house 1-108 (296) Show / Hide 
Range on Protein: 373-473
Range on HMM: 1-108/296
Sequence Identity: 33% (36 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPK-ADEVA---EYLAEIE---MLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSY
.|.|| ||.||||.||.|.. . .  ... .||||....  .  .| .   . . |     |.| .  | ||. ..| ||   | ....||  .|.|.||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRTVRKEA
||. |...
LRRHRPTP
Kinase CG3277.AA RTKB 373-470 35 5.4e-21 67.54 In-house 1-97 (264) Show / Hide 
Range on Protein: 373-470
Range on HMM: 1-97/264
Sequence Identity: 35% (35 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVR
...|. ||.||||.|  |  . .| | .. ..|.|.|||     |  . ..|. ..| .|.| ||.  .| |    ||.   |. . |||  |||  |
VWLGEKLGNGAFGEVFQA-WVRNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCR
Kinase CG3277.AA Fer 373-468 30 7.6e-19 60.91 In-house 1-102 (283) Show / Hide 
Range on Protein: 373-468
Range on HMM: 1-102/283
Sequence Identity: 30% (31 aa)

IQIGRMLGEGAFGQVHEAT-AINLRR-MRGTT---IVAVKQLKPN-PKADEVAEYLAEIEMLKG-VGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSY
. .| .||||||| |. .. .. . . .. ..    |.|| .| . ..... .| ..|  ...     | ||| | | |. . |.. .||..| |.|.||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYD-HPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSY

LRT
|..
LKK
Kinase CG3277.AA S_TKc 373-738 14 5e-16 58.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 373-738
Range on HMM: 1-231/231
Sequence Identity: 14% (55 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKE
 .|.| .|.||||.|. .. ..        |||.|..|                                                              
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------------------------------------------------------------

ASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAESKLVALGLTSWAKSVNENLISATYTIV------
                                                                    . .   .    |   .|..   ....      
--------------------------------------------------------------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYM

-----ED--EDAFEYILDNK----------ELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHGIYTNTRTRKLPLRWLSIEAI
     .    | |.|| ...          .   .. ||.... .. .. | ||||   |.|.|.  ..||.||||.|.      .|    . ... | .
VMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL

RENVYSS-KSDIWAYGVVLWEIGTLGASPYPTISNDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTFDALYK--VLSPKTTYV
    |.  |.|.|. |..|.|  . |  |.|    ....  ..           .|..  .. .|.  .||.|||   . .  ..  .  ..
---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG3277.AA Src 373-478 29 8.4e-16 50.12 In-house 1-98 (255) Show / Hide 
Range on Protein: 373-478
Range on HMM: 1-98/255
Sequence Identity: 29% (32 aa)

IQIGRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLR-TVRK
|.  | ||.| || | ...       .|.| |||| |||     ... .|.|.. .| .  | ..|. .  |. . |.. . || ..|.|| ||. . . 
IKLCRKLGQGQFGEVWMGY------WNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEG

EASKLRN
 . .|..
RHLHLPQ
Kinase CG3277.AA KIN6 404-483 34 6.4e-08 22.04 In-house 47-126 (305) Show / Hide 
Range on Protein: 404-483
Range on HMM: 47-126/305
Sequence Identity: 34% (29 aa)

VAVKQLKPNPK-ADEVA--EYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKEASKLRNRNANY
.||| |   |. ||| |  . . ||.  |  | |  .|. ||| |   . . . ||  ...|| |||  .... .|     ||
CAVKML---PSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYCCHMDLLKYLRNRCQYMMNLDDLGINY
Kinase CG3277.AA KIN6 373-387 46 0.036732 2.71 In-house 1-15 (305) Show / Hide 
Range on Protein: 373-387
Range on HMM: 1-15/305
Sequence Identity: 46% (7 aa)

IQIGRMLGEGAFGQV
|.    ||.|||. |
IHKDHKLGHGAFCNV