Pka-C2

Species: Fruit Fly
Alias: CdkB, CG12066, Pka-C2, PKA C2, DC1a, SFO213, DC1
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 100A2,

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
Pka-C2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
Pka-C2.AA Protein Various 354 None Fasta, JSON

Protein domain

Protein domains of Pka-C2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Pka-C2.AA PKA 45-301 53 6.00000000001e-181 607.43 In-house 1-263 (263) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-263/263
Sequence Identity: 53% (140 aa)

YITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIY-LVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEK
. . ..||.||||.|||.|.|...|||| ||..|.. |||||| ||||||..|.. ..||... . .......|||.....|.|||.|||.|....|...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

HARFYAA-QVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLR-PYNKSVDWWAFGILVYEFVAGRSPFA
||.|||| |. |||||.|.....||||||||||.|..|.||||||||.|.||.||.|||||||||||||.| . ...|||||||.|||.||..|| .|| 
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

IHNRDVILMYSKICICDYKMPSYFTSQL---RSLVESLMQVDTSKRLGNSNDGSSDVKSHPWF
 ||||.. .| ||| ...|.|..|.|..   ..|...|.|||..||.||  .|. |.| |.||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase Pka-C2.AA AGC 45-301 28 1.9e-157 410.58 In-house 1-395 (395) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-395/395
Sequence Identity: 28% (115 aa)

YITRAVLGNGSFGTVMLVREK------SGKNYYAAKMMSKED-LVRLK--QVAHVHNE------------KHVLNAAR----------FPFLIY-LVDST
.    |.| ||||.|.|||.|      . . ||| |...|..  |..|  .|.|...|            ...|  ..           ||..  |  | 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KCFDY--LYLILPLVN---------GG-ELFSYHR---RVRKFNEKHARFYAAQ-------VALALEYMHK-MHLMYRD-LKPENILLDQRGYIKITDFG
.  |.  ||... ...         || |||.. .   . ..|.|..||||||.       ..|||||.|. |.  .|| |||||||||..|.||.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FTKRVDG-----------------------------------------------------RTSTLCG--TPEYLAPEIVQLRPYNKSVDWWA--FGILVY
. |.. .                                                     ||.|.||  ||||.||||.    |.|..|||.  .|.| |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFVAGRSPFAIHNRD--------VILMYSKIC------ICDYKMP----------SYFTSQLRSLVESLMQVDTSKRLG-NSND----GSSDVKSHPWF
|...|..||  .|..           |. ||.       .. |.|          ..|......|.. |...| .|||| . ||    | ...|.||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase Pka-C2.AA AktR 45-301 41 1.7e-104 353.42 In-house 1-268 (268) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-268/268
Sequence Identity: 41% (111 aa)

YITRAVLGNGSFGTVMLVREK-SGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLN-AARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNE
.   ..||.| ||.|.||..|   . .|| || .|.......|  |. .|. ..   ...||.. |... .  ..|..|.  . |||||..... .||.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

KHARFYAAQVALALEYMHKM-HLMYRDLKPENILLDQRGYIKITDFGFTK----R-VDGRTSTLCGTPEYLAPEIVQL-RPYNKSVDWWAFGILVYEFVA
. ||||.||. ||||| |.  . .||||||||||||. |..|||||| .|    .  | .. ..||||||.|||...   ..|||||||||||..|| |.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRSPFAIHNRDVILMYSKICI-CDYKMPSYFTSQLRSLVE-SLMQVDTSKRLGNSNDGSSDVKSHPWF
|  ||  .|.  .. . ||.     . ||||.||...|..  |.. .  |||| .. | ...||||||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase Pka-C2.AA SGK 45-301 34 2.3e-103 320.08 In-house 1-283 (283) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-283/283
Sequence Identity: 34% (100 aa)

YITRAVLGNGSFGTVMLVREKSG------------------KNYYAAKMMSKEDLV-------RLKQVAHVHNEK-HVLNAARFPFLIYLVDSTKCFDYL
 .   |.| |||| |..|. |.                   .  || |  .|.  .       . |.. |.  |.  .|.  . ||.. |  .    ..|
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTK---RVDGRTSTLCGTPEYLAPEIVQLR
|. .  |||||.|.. .| ..| |  ||||||....|||| |.    ||||||||||||  |....||||  |        |.| ||||||||||. . .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWF
|. ..||||  |.. ||.  |  ||   .|.. .|| .|   . ..| ..... ..| . | | | .|||| ..... ..|.||.|
PHDRTVDWWCLGCVLYEMMYGLPPF--YSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF

Kinase Pka-C2.AA Akt 50-301 41 7e-99 316.73 In-house 6-264 (264) Show / Hide
Range on Protein: 50-301
Range on HMM: 6-264/264
Sequence Identity: 41% (108 aa)

VLGNGSFGTVMLVREKSGKNYY-AAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFY
||| |||| |.||..|. ...| | |. .|. ..  .||.|.  |. .|   ..||.. |. |    |.||...  .||||||.. .| |.|.|. ||||
VLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFY

AAQVALALEYMHKMHLMYRD-LKPENILLDQRGYIKITDFGFTK-R-VDG--RTSTLCGTPEYLAPEIVQLRPYNKSVDWWA-FGILVYEFVAGRSPFAI
.|.. ||.|. |..  .||| |||||||.|. |.|..||||  |   .    .| |.||||||||||| .   . |.||||. .|.. ||.  || ||  
CAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF--

HNRDVILMYSKICICDYKMP--SYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWF
.|.|.  |. ||  ...|.|  ...  . ..|...| . | .||||. ...  ..|.||||
YNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase Pka-C2.AA S_TKc 45-301 32 3.8e-92 313.35 SMART 1-231 (231) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNG--GELFSYHRRVRK---
|    ..| |.||.|...|.|. . ..| |...           |. .|  .|   . |... | |.    |.||... ...|  |.||.| .. ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNK-SVDWWAFGILVYEFVA
   |.| |||||..|...||||.|... ..|||||||||||.   |||.|||. ...    .|.||||.|.|||..   .|.| ..|||..|...||...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGS--SDVKSHPWF
|. ||     .. .|. ||.          ......... ..|.| .||..        .|.|.||||
GYPPFP----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase Pka-C2.AA Ciliate-E2b 45-301 34 8.1e-86 260.73 In-house 1-272 (272) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-272/272
Sequence Identity: 34% (96 aa)

YITRAVLGNGSFGTVMLVRE-KSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVR--KFN
 |    ||.| || | ||.. |. |.||| |  ||  ..      |  .|| ||  . .||.. ...| |  ...|... ..||.|||.. | .    ..
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

EKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGRTS------TLCGTPEYLAPEIVQ-----LRPYNKSVDWWAFGILV
.. ..|| |.. |.||| |.   .|||.|||||..|. ||.|. |.|  |  ... .      |..|||.|.||||.|      ..|. .|| |..||  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YEFVAGRSPFAIHNRDVILMYSKICIC--DYKMPSYFTSQLR--SLVESLMQVDTSKRLGNSNDGSSDVKSHPWF
|||  |. |.|   .| .  | .|     . . |||.. ..   .|.....|     ||| | .     ||||||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYS---WLKSHPWF

Kinase Pka-C2.AA PKC 45-301 40 1.1e-80 261.26 In-house 1-262 (262) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-262/262
Sequence Identity: 40% (107 aa)

YITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLN-AARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEK
     ||| |||| |||.. |  . ||| | . |.  .    |  . .||.||  |.. |||  |  .    |.|. ..  |||| |     ..|.|.|.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

HARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTK---RVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPF
||||||| ...|| ..|.    ||||| .|.|||. | |||.|||  |   . . .||| ||||.|.||||.|  .|.|||||||||.| ||. ||.|||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

AIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDG---SSDVKSHPWF
 . . |   .   |.  .   | ...    |. ...|. . .||||   ..   . |...|| |
HGEDEDE--LFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase Pka-C2.AA RSK 48-301 34 3.5e-77 262.73 In-house 1-278 (278) Show / Hide
Range on Protein: 48-301
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)

RAVLGNGSFGTVMLVREK---SGKNYYAAKMMSKEDLVRLKQ-VAHVHNEKHVLNAAR-FPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRK---
  ||| |..| | |.|..     . .|| |  .|  .|. .  ..|.  |  .| . .  ||.. | .. .  ..||||. ...|||||   .. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQ---RGYIKITDFGFTKR--VD--GRTSTLCGTPEYLAPEIVQ---LRP-YNKSVDWWAFGI
| |. |.||.|...||.|..|. .  .|||||||||.|.   .| ||.||||| |    |  ..| | |.| ||.|||..     .  ..|..||| .|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LVYEFVAGRSPFAI---HNRDVILMYSKICICD--YKMP--SYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWF
| ||  .|..||.     ||..|.   .|. ..   .||  .| .   ..|.  ....| .||||   .. ...|.||||
LMYEMLTGCPPFQGPNDNNRKEIM--KRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase Pka-C2.AA Ciliate-E2 45-301 22 1.8e-72 247.1 In-house 1-365 (365) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YITRAVLGNGSFGTVMLVRE-KSGKNY----------------------YAAKMMSKEDLVRLKQVAHVH----------NEKHVLNAARFPFLIYLVDS
|.   ..|.|.||.| ...  | .|..                      || |.|.| ..  .||. |.           ||| .|    .|..| ....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TK--CFDYLYLILPLVNGGELFSYHR-------------------RVRKFNEKHAR-------FYAAQVALALEYMHKMH-LMYRDLKPENILLDQRGYI
 .    ...||.. ...||.||.| .                    .... .. ..       ||.|.. |||||.|. .  ..||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGFTKRVDG----------------------------------RTSTLCGTPEYLAPEIVQLRP---------YNKSVDWWAFGILVYEFVAGRSP
||.|||. |..|                                    . |.||||.|.||||..  .         |....|.|..|.. ||.. |. |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FAIHNRDVILMYSKICICDYKMP------------------SYFTSQLRSLVES----LMQVDTSKRLGNSNDGSSDVKSHPWF
|          . .|. |... |                   . . .   |       ..|.| .||..    | .... ||||
F----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF

Kinase Pka-C2.AA Delta 45-301 38 8.5e-71 241.51 In-house 1-259 (259) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-259/259
Sequence Identity: 38% (100 aa)

YITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLN-AARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEK
.. ..||| |||| |||.  |  ..||| | . |. ..    |     |..||  |.. |||  |. . .  ..|. ..  .|||.|      ...|.||
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

HARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKR---VDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPF
 |||||. . ..|...||  ..||||| .|.|||. | ||| |||  |.    ....|| ||||.|.||||.. . ||.|||||.||.|.|| . | |||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

AIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWF
  | .|   ..  ||      | . | . ..... |.. |  ||||  .    |.. |..|
--HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF

Kinase Pka-C2.AA Pkinase 45-301 27 2.3e-69 241.53 Pfam 1-293 (293) Show / Hide
Range on Protein: 45-301
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

YITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVH-NEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGG----ELF-----SYH
| .  ..| ||||.| . ..|.    .| | ..|..    |...|.. .| ....  . |. . | |.    |..|.......||    .||     ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYI----KITDFGFT----KRVDGRTSTLCGTPEYLAPEIVQ-LRPYNKSVDWWA
...  | |....||. |.. .|||.|.|  ..|||||||||.|..|.|    ||.|||.        .. ..|.||||.|.|||...  ..| ..||.|.
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGILVYEFVAGRSPFAIH----NRDVILMYSKICICDYKMPSYFT---------------------SQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPW
.|...||.. || ||  |    |.| . |. .|  .... ... .                     . ........ ..| .||..       ... |||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPW

F
|
F

Kinase Pka-C2.AA TyrKc 45-295 18 3.2e-12 -25.12 SMART 1-280 (280) Show / Hide
Range on Protein: 45-295
Range on HMM: 1-280/280
Sequence Identity: 18% (53 aa)

YITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAA--RFPFLIYLV-DSTKCF------DYLYLILPLVNGGELFSYHR
     .||.| ||.|.. . |      | ||. ..       ..  ..|  ..     . | .. |.   |. .      . |.... .. .| | .| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RVRK-FNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGR------TSTLC-----GTPE-----YLAPEIVQLRPYN
. |. .. |.   .. |.|   || |....  |||   |.|.. .. .||.||| .. ..        ...       |.        .|||  . . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KSVDWWAFGILVYEFVA-GRSPFAI-----HNRDVILMYSKICICDYKMPSY-------FTSQLRSLVESLMQVDTSKRLGNSNDGSSDV
   | |.||.. .|    | .|         . . .. | |      ..|..        .. . .. ..  . | ..|   |.   .. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF

Kinase Pka-C2.AA S_TK_X 302-354 17 1.1e-11 46.09 SMART 1-79 (79) Show / Hide
Range on Protein: 302-354
Range on HMM: 1-79/79
Sequence Identity: 17% (14 aa)

QGVDWFGILN--QEVTAPYQPTIS----GAEDLSNFE-NFEFKDRYKSRINR-------------------HPELFANF
 |.|| ...|  .|...|..|.|.    ...|.|||.  |. ..   . ...                    ......|
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase Pka-C2.AA Pkinase_Tyr 117-241 24 0.000122 16.34 Pfam 81-217 (270) Show / Hide
Range on Protein: 117-241
Range on HMM: 81-217/270
Sequence Identity: 24% (33 aa)

YLYLILPLVNGGELFSYHRR----VRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRV--DGRT-STLCGTPE---Y
..|...... .| | .| |.     .... |.   ...|.| ..|| . ...  |||   |.|..  . .||.||| .. .  |.    .  |..     
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKW

LAPEIVQLRPYNKSVDWWAFGILVYEFVA-GRSP-FA
.|||  . . ..   | |.||.| .| .  |..| ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYP