Gene CG8565 (Fruit Fly)

CG8565

Species: Fruit Fly
Alias: SFO140, CG8565, SPRK2
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 13F9--10

Classification

Group: CMGC
Family: SRPK

Sequence

Name Sequence Type Origin Length Description Download
CG8565.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 323 Kinase domain by global Sugen HMM Fasta, JSON
CG8565.AA Protein Various 790 None Fasta, JSON

Protein domain

Protein domains of CG8565.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG8565.AA SRPK 552-722 51 6.00000000001e-151 392.05 In-house 385-554 (554) Show / Hide 
Range on Protein: 552-722
Range on HMM: 385-554/554
Sequence Identity: 51% (88 aa)

PANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIR
.|. ......|||||||||..|||||.||||..||..|||.||||...|||||.||...|||||.|||..||... |. |..|||.|.|.||.|||....
NADLDHKIKIKIADLGNACWVHHHFTEDIQTRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEPHSGED-YSRDDDHIAHIIELCGKIPWHFAL

KGKHSRNFINSAGKLCNIETLKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYL
.||.||.|.|..|.|..|..|||..|.|.||..|.|.......|..||||||..||..|..|...|....|
SGKYSREFFNKKGELRHIPKLKPWPLMNVLIEKYEWSHEEAKQFEDFLMPMLHYNPEKRATAKECLQHPWL
Kinase CG8565.AA SRPK 203-389 44 6.8e-141 365.53 In-house 1-206 (554) Show / Hide 
Range on Protein: 203-389
Range on HMM: 1-206/554
Sequence Identity: 44% (94 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQH----------------------KYRSHVVGFYDFFEITGPHG
|||..|||||||||||||.|.|.|||.|.|..|||..|.||..|||.|..... ||..                      ..|.|||...|.|...||.|
YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNG

RHICLVLEVLGDNLLKVIERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAK
.|.|.|.||||.||||.|....|.|||....||||.|||.||..||..|||||||.|||||||. |.  ..  .  . |..    .|. .|||.|..||.
NHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLCVNQDYIKRMAAEWTEWQ---KMGMQMPSSSMVQTAP

RRMQAKSKK
.  ... ..
QHQTQCQQQ
Kinase CG8565.AA CMGC 554-722 19 2.2e-49 159.94 In-house 218-513 (513) Show / Hide 
Range on Protein: 554-722
Range on HMM: 218-513/513
Sequence Identity: 19% (58 aa)

NNECDV------------------RVKIADLGNACYFHHH------------------------FTDDIQTKEYRALEVILGAG----------YCETAD
|..|..                  |.||.| |.|...|.|                        .|....|  ||| |..||..          |... |
NHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPID

IWSVACLLWELATG--------TYLFDTHSKR------GKYNLDEVHIAKIVETCGRIPWYLIRKGK-------HSRNFINSAGKLCNIETLK-------
.|||.| . |. ||         .|| .|| .      || ..|  ...||....| .. ..|.|||       |.....|  ... .. ..|       
MWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHID--QLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTM

------------------PLKLANILIRWYGW--------------------------------RTRQSTEFVNFLMPMLQTNPLSRISASKALESHYL
                  | .  . . ... |                                |.... .....|. ||| .|  ||.|. ||.  |.
TNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CG8565.AA CMGC 203-355 20 7.8e-46 148.04 In-house 1-244 (513) Show / Hide 
Range on Protein: 203-355
Range on HMM: 1-244/513
Sequence Identity: 20% (51 aa)

YHVFKKLGWGHFSTVWLCYD--------------TQMDRYCAVKVSKSAQVYKETGI-------------DEIMLFSQMS-LHDQHK----------YRS
|.. ||.|.|....|. |.|              .. ....|.|  |... |.|..              .||..  ...  ||. .           . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

HVVGFYDFFEITGPHGR-------------HICLVLEVLGDNLLKVIERCF--YKG------------------------MPISNIKQIAQQVLTGLK--
..|. ||.|   ...|              |..|| | .. .|...|...   |.|                        ..| .|. ...|.|.|||  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

FLHEECG-IIHTDLKPENVLLASNEVS---------------VRTEIK
..|  .| |||.||||||.|. .|  .               .. ..|
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLK
Kinase CG8565.AA S_TKc 203-722 13 9.4e-38 132.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 203-722
Range on HMM: 1-231/231
Sequence Identity: 13% (71 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGD---NLLKVIE
|.. .|.| | |..|..|...  .|..|.|. |      |. . || . ..     .|.   ..| .||.|.       |...|.| ..    .|...|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-----HHP---NIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIK

RCFYKG----MPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIK-----TAIEVYLKANEGKLSPSSKMTKTAKRRMQAKSKKV
.. ..|    .|   .. ...|.. .|...|.  |||| ||||||.|| .       .||      | ..                              
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-------HIKICDFGLARQL------------------------------

ISFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDGFMMMSDADCRTVQNSKLPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKN
                                                                                                    
----------------------------------------------------------------------------------------------------

LDEKELSTQDKRRRFTQASGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIYPIDPANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEV
                                                                                      |  . | .|.| ||
--------------------------------------------------------------------------------------TTFCGTPWYMAPEV

ILGAGYCE-TADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANILIRWYGWRT
.   ||    .|.||. |.|.|...|  .|.          ..  . |..                                                  
L---GYGKCKCDWWSCGCILYEMLCGYPPFP----------QMQMMFKKIG-------------------------------------------------

RQSTEFVNFLMPMLQTNPLSRISASKALE-------SHYL
  | |. .|.. .|| .|  |..| .||.         ..
--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG8565.AA CLK 203-396 22 2.5e-31 90.6 In-house 1-183 (350) Show / Hide 
Range on Protein: 203-396
Range on HMM: 1-183/350
Sequence Identity: 22% (48 aa)

YHVFKKLGWGHFSTVWLCYDTQM-DRYCAVKVSKSAQVYKETGIDEIM--LFSQMSL-HDQHKYRSHVVGFYDFFEITGPH-GRHICLVLEVLGDNLLKV
| . ..|| | |..|  | |... ..| |.|. ...  |.|    ||   . .     . . ||..|..  .| |    .. . |||.| | .| ..  .
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWF----DYGHGHICIVFELYGLSIYDF

IERCF------YKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASN-----EVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAKRRMQAK
.          |.. ||. |...| | .. .|||| . ...|||||||| ....      . .. ...|  |.                     ..   .
MKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLH-DMKLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKIN---------------------KKS-NN

SKKVISFFKN
... ..  ||
CVCHYWHVKN
Kinase CG8565.AA DYRK 203-343 31 1.1e-29 105.01 In-house 1-137 (320) Show / Hide 
Range on Protein: 203-343
Range on HMM: 1-137/320
Sequence Identity: 31% (45 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCF
| ... .| | |. |  |.|.. . . |.|. .. . .  ....|| . . .. .    ...|.| .||.|     |  | |.| | |  ||  .. .  
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFY----HRNHLCIVFELLSMNLYEFLKNNH

YKGM-PISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLL
 .|  ........|||.||.|||||..  ||| ||||||..|
FQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIML
Kinase CG8565.AA HIPK 203-343 35 1.2e-23 70.92 In-house 1-134 (329) Show / Hide 
Range on Protein: 203-343
Range on HMM: 1-134/329
Sequence Identity: 35% (50 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCF
| |   || | |  |  |     .   |.|. |    |   |  |. . . .|  .   |  |.| .|..|.    |  |.||| |.|  ||        
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEY--HFVRAYECFH----HKNHTCLVFEMLEQNLYDFQKQNK

YKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLL
.  .|.  |. | ||||| |. |  | |.|| ||||||..|
FMPLPLKHIRPILQQVLTALMKLK-ELGLIHADLKPENIML
Kinase CG8565.AA CLK 561-625 42 2.4e-23 66.2 In-house 186-253 (350) Show / Hide 
Range on Protein: 561-625
Range on HMM: 186-253/350
Sequence Identity: 42% (29 aa)

VKIADLGNAC---YFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKR
... | |.|    . | | .. ..|. ||| ||||| |. .  |.||..| | || ||  ||.||..|
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNR
Kinase CG8565.AA DYRK 554-722 27 9.5e-23 81.9 In-house 138-320 (320) Show / Hide 
Range on Protein: 554-722
Range on HMM: 138-320/320
Sequence Identity: 27% (53 aa)

NNE-CDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVH-IAKIVETCGRIPWYLIR
... .  ..|..| | .|. |....  || . ||| |||||  ||.  |.||. | | || ||  ||         . .|.. .|.|.|. | .|  .|.
KQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFP--------GENEYDQLACIMEVLGMPPKWMID

KG--KHSRNFINSAGKLCNIETLKP-LK-------------LANILIRWYGWR------TRQSTEFVNFLMPMLQTNPLSRISASKALESHYL
||  .. ..|...  . | ... .   |             .. . .|  | |      ...  .|..|.. .|| .| .||..| ||.   .
KGRCRRKHKFFDC-FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase CG8565.AA Pkinase 203-348 27 4.9e-21 75.46 Pfam 1-146 (293) Show / Hide 
Range on Protein: 203-348
Range on HMM: 1-146/293
Sequence Identity: 27% (44 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGID-----EIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGD-----
||. .|.| | |..|..|..    .  |||. |     ..  .      || .   ..    |..   .| .||.||     ..||..|.| ..      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPN---IVRLYDWFED----KDHIYMVMEYCEGGLYVM

NLLKVIERCFYKGM--PISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEV
 |  .|..  ....  .   .| .. |.| ||...|. .|||| ||||||.|. .| .
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGH
Kinase CG8565.AA DYRK2 203-343 29 8.3e-20 60.79 In-house 1-135 (318) Show / Hide 
Range on Protein: 203-343
Range on HMM: 1-135/318
Sequence Identity: 29% (41 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCF
| . . .| | |  |  |||   . . |.|.    . . ..   ||   . .. .|.    . .|   |.|   .    |.|...| |. || . | .  
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDN-TMNCVHMLDYFYFRN----HHCITFELLSMNLYEYIKKNH

YKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLL
..|   ...   |...|..|.|||..  ||| ||||||.||
FQGFSLQLVRRFAHSILQCLRFLHKNN-IIHCDLKPENILL
Kinase CG8565.AA DYRK1 203-343 33 1e-19 65.52 In-house 1-137 (321) Show / Hide 
Range on Protein: 203-343
Range on HMM: 1-137/321
Sequence Identity: 33% (47 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCF
| .   .| | |  |   ||.|   | |.|. |  . . .    || |   |  ||. . . ..|     |     .  |.|||.|.|  ||  ..    
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEM-KYYIVHLKRHFM----FRNHLCLVFELLSYNLYDLLRNTH

YKGMPISNIKQIAQQVLTGLKFLHE-ECGIIHTDLKPENVLL
..|. .  ....|||..| | |.   |  ||| ||||||.||
FRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILL
Kinase CG8565.AA DyrkP 561-659 35 3.6e-17 52.45 In-house 147-238 (323) Show / Hide 
Range on Protein: 561-659
Range on HMM: 147-238/323
Sequence Identity: 35% (35 aa)

VKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNF
||| | | .|. | |    .| . ||| |||.|  |    |.||. |.| || ||  ||      |        .|...   | .| .... |.  .||
VKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQNDNIQG-------LLARVIGIIGPFPEWMMQEGRLVQNF
Kinase CG8565.AA Ciliate-E2-Unclassified 203-346 20 6.5e-15 48.19 In-house 1-180 (352) Show / Hide 
Range on Protein: 203-346
Range on HMM: 1-180/352
Sequence Identity: 20% (39 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYC-----AVKVSKSAQVYKETGIDEIMLF-SQMSLHD---------------QHKYRSHVVGFYDFFEITGPHGR
|.. |..| | |..|..|.. . . .      . |. . .| .... . |||.   .|  .                .. .  ..| ... |. .     
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ----

HICLVLEVL-GDNLLKVIE--------------RCFY-KGMPISNIK-----QIAQQVLTGLKFLHEECGIIHTDLKPENVLLASN
.|..|.| . | .|.. |.              .. . |  .  ..|     ... |.| ||..||.. .||| |.||||.|. .|
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNN
Kinase CG8565.AA YAK 203-343 36 2.9e-14 44.47 In-house 1-139 (347) Show / Hide 
Range on Protein: 203-343
Range on HMM: 1-139/347
Sequence Identity: 36% (53 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHK-----YRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKV
| |   || | |  |  |     .   |||| |. | |   .. || .    .| .||      |  |..  |||| .   |  | ||| | |  ||   
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQIL--RVLNQQHDPNNKNYQKHILRMYDFF-V---HKNHFCLVFEMLSNNLYEY

IERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLL
.    ..|. .. |.|   |.| |.  | |.  ||| ||||||..|
LKQNKFCGFSFQLIRQWTKQILDGMCVL-ENKQIIHCDLKPENIML
Kinase CG8565.AA DyrkP 203-345 29 4.2e-12 35.46 In-house 1-141 (323) Show / Hide 
Range on Protein: 203-345
Range on HMM: 1-141/323
Sequence Identity: 29% (43 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVI----
| .   ||   ||    | | | ..   .|.    . | .  |||| |   .        .  |. .||.|     |  |. .. |.| |||        
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEK-NVLRYYDYFY----HKEHLFIITELLKDNLYEFYKFNR

ERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLAS
|    .   .  ...| ||.| .| ..|    .|| ||||||.|. |
ENEQQRYFTVGRLQKITQQILIALDYIH-SLRLIHCDLKPENILMKS
Kinase CG8565.AA DYRK2 561-619 43 1.4e-11 33.55 In-house 143-202 (318) Show / Hide 
Range on Protein: 561-619
Range on HMM: 143-202/318
Sequence Identity: 43% (26 aa)

VKIADLGNACYFHH-HFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLF
.|..| |  |. |  ..  .||.  ||| |||||  |    |.||  | . || ||. ||
IKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF
Kinase CG8565.AA Pkinase 550-628 31 7.8e-11 39.39 Pfam 141-224 (293) Show / Hide 
Range on Protein: 550-628
Range on HMM: 141-224/293
Sequence Identity: 31% (28 aa)

IDPANNECDVRVKIADLGNAC---YFHHHFTDDIQ-TKEYRALEVIL-GAGYCETADIWSVACLLWELATGTYLFDTH----SKRGKY
||  |...| .|||.| | |.   | . . ....  | .|.| |||. | .|   .|.||. |.|.|...|  .|. |    . . ..
ID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQM
Kinase CG8565.AA DYRK1 561-659 33 1.8e-10 32.46 In-house 145-236 (321) Show / Hide 
Range on Protein: 561-659
Range on HMM: 145-236/321
Sequence Identity: 33% (33 aa)

VKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNF
.|| | | .|   .     || . ||. ||.||  |    |.||. |.| |. ||  ||      |.  .|   . ||||  |  | ..| ..  .. .
IKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLF-----SGSNEVDQ--MNKIVEVLGMPPKHMIDQAPKAHKY
Kinase CG8565.AA Ciliate-E2-Unclassified 560-722 18 1.1e-08 26.24 In-house 185-352 (352) Show / Hide 
Range on Protein: 560-722
Range on HMM: 185-352/352
Sequence Identity: 18% (36 aa)

RVKIADLGNACYF------------------HHHFTDDIQTKEYR----ALEVILGAGYCET----ADIWSVACLLWELATGTYLFDTHSKRGKYNLDEV
..||.|.|.. .                   ...... ..| .|     | ||. | .| ..    .||||. ..| |. .|.| |.  ..  ...| . 
YIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQ

HIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLAN-ILIRWYGW------RTRQSTEFVN-FLMPMLQTNPLSRISASKALESHYL
 |  .                        |     .. |.  .... | .... |         .  .|.| .|  ||. || .||.....|. ...
WI-NN------------------------A----YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CG8565.AA YAK 561-612 36 2.3e-08 24.14 In-house 147-198 (347) Show / Hide 
Range on Protein: 561-612
Range on HMM: 147-198/347
Sequence Identity: 36% (19 aa)

VKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWEL
.|| | | .|.     .  || . ||. |.|..  ||   | ||  | . ||
IKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAEL
Kinase CG8565.AA HIPK 560-612 40 9.6e-08 19.94 In-house 143-196 (329) Show / Hide 
Range on Protein: 560-612
Range on HMM: 143-196/329
Sequence Identity: 40% (22 aa)

RVKIADLGNACYFHHHFTDD-IQTKEYRALEVILGAGYCETADIWSVACLLWEL
|||. | | | .. .  ..  .| . ||| |.|||  .||  |.||  | . ||
RVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAEL
Kinase CG8565.AA TyrKc 203-401 14 1.8e-05 -134.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 203-401
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

YHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQM-SLHDQHKYRSHVVGFYDFFEITGPHG-----RHICLVLE-VLGDNLL
 .  |||| |.| .|...  .   . .|||. |.    .|  ..|. . ..    |.      ..| .|    .| . .       ...|.| . . .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHP------NIVRLYGV--CTQQGRNFMYIEPLMIVMEYMPHGDLK

KVIERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNE-----------------------VSVRT----EIK-------TAIEVY
. . ..  |  . .   ... |.  |  .||.  ..|| ||   |.|...|                           |.      |       .|.|. 
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LKA-------------------NEGKLSPSS------------KMTKTAKRRMQAKS-----------------KKVISF-------FKNHRRML
 .                      |.  ..             .  |. .|..| ..                 |.   .       |.. .. .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CG8565.AA HIPK 694-722 31 0.001289 6.71 In-house 301-329 (329) Show / Hide 
Range on Protein: 694-722
Range on HMM: 301-329/329
Sequence Identity: 31% (9 aa)

EFVNFLMPMLQTNPLSRISASKALESHYL
|||. |  |. ... .||. ..||.... 
EFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase CG8565.AA DYRK2 691-722 21 0.005718 5.12 In-house 287-318 (318) Show / Hide 
Range on Protein: 691-722
Range on HMM: 287-318/318
Sequence Identity: 21% (7 aa)

QSTEFVNFLMPMLQTNPLSRISASKALESHYL
..  |..|..  ..  | .|...| ||.  ..
EDENFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase CG8565.AA YAK 695-722 28 0.053516 2.13 In-house 320-347 (347) Show / Hide 
Range on Protein: 695-722
Range on HMM: 320-347/347
Sequence Identity: 28% (8 aa)

FVNFLMPMLQTNPLSRISASKALESHYL
|. |.  .|| ||. | ... | .  ..
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase CG8565.AA Pkinase 702-722 23 0.101054 7.17 Pfam 273-293 (293) Show / Hide 
Range on Protein: 702-722
Range on HMM: 273-293/293
Sequence Identity: 23% (5 aa)

MLQTNPLSRISASKALESHYL
.|. .| .|..|  .|.. ..
CLCKDPKKRPTAEQILQHPWF
Kinase CG8565.AA DYRK1 695-722 32 0.181856 0.33 In-house 294-321 (321) Show / Hide 
Range on Protein: 695-722
Range on HMM: 294-321/321
Sequence Identity: 32% (9 aa)

FVNFLMPMLQTNPLSRISASKALESHYL
|   .  ||| .| .||.  .||.  ..
FKDLIKRMLQYDPKQRITPYYALQHSFF