Gene put (Fruit Fly)

put

Species: Fruit Fly
Alias: Tgf-r: TGF-beta-type-receptor-like, Activin-A-receptor-88CD, dlhC: dorsal holes C, Act-r, TGF-B, SFO046, Atr-II, Atr: Activin-A-receptor-88CD, dorsal holes C, pun, TGF-beta-type-receptor-like, activin receptor, activin receptor type II, Atr88CD, l(3)10460, Punt, TGF-beta, put, CG7904, STK-C, Tgf-r: TGF-beta-type-receptor-li, AtrII, l(3)j5A5, punt
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 88C9

Classification

Group: TKL
Family: STKR
Subfamily: STKR2

Sequence

Name Sequence Type Origin Length Description Download
put.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 283 Kinase domain by global Sugen HMM Fasta, JSON
put.AA Protein Various 516 None Fasta, JSON

Protein domain

Protein domains of put.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Activin_recp put.AA Activin_recp 34-128 23 5.1e-28 94.69 Pfam 1-121 (121) Show / Hide 
Range on Protein: 34-128
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

IECEHFDEKM------CN-TTQQCETRIEHCKMEADK------FPSCYVLWSVNE----TTGILRIKMKGCFTDMHECNQ---TECVT-----SAEPRQG
..|.......      |. . ...|.....| ...||       ..|||.|..|.    |. . |..|.||..... |.|    .|..     | ..|.|
LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG

NIHFC-CCKGSRCNSNQKYIK
. |.| ||... ||.|. .  
HNHECWCCETDYCNRNLTPPP
Kinase put.AA Type2 202-487 57 1.1e-210 702.13 In-house 1-315 (315) Show / Hide 
Range on Protein: 202-487
Range on HMM: 1-315/315
Sequence Identity: 57% (181 aa)

IQLLEQKASGRFGDVWQAKLNNQ-----DVAVKIFRMQEKESWTTEHDIYKLP-RMRHPNILEFLGVEK---HMD--KPEYWLISTYQHNGSLCDYLKSH
|||.|....||||.||.|...|.     .||||||..|.|.||..|.|||.|| .|.|.|||.|...||   ||.  ..||||.....|.||||||||.|
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

TISWPELCRIAESMANGLAHLHEEIP-ASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPC--------GDTH--GQVGTRRYMAPEV
||.|.|.||.|.|||.|||||||||. ...||..||.|||||.||||||.|.|.|.|||||||||.|.|||..        ||||  |||||||||||||
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

LEGAINFN--RDAFLRIDVYACGLVLWEMVSRCDFAG---PVGEFQLPFEAELGLR-PSLDEVQESVVMKKLRPRLLNSWRAHPGLN-VFCDTMEECWDH
||||.||.  ||||...|.||.|||||||||||....   .|.|.|.|||.|.|.. ||....||.||.|. ||.. ..|..|||.. ..|.|.|.||||
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH

DAEARLSSSCVMERF
||||||...||.||.
DAEARLTAQCVQERM
Kinase put.AA STKR 202-487 49 1.1e-191 624.42 In-house 1-312 (312) Show / Hide 
Range on Protein: 202-487
Range on HMM: 1-312/312
Sequence Identity: 49% (153 aa)

IQLLEQKASGRFGDVWQAKLNN----QDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVE-KHMD--KPEYWLISTYQHNGSLCDYLKSHTISW
|||.|....||.| ||..|...    ..|||||| .....|| .|..||..| |||.|||.|.. . ||..  . .||||. |..|||||||||.|||.|
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

PELCRIAESMANGLAHLHEEIP-ASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHG---------QVGTRRYMAPEVLEGAI
.|.||.|.|||.||||||.||. ... .. ||.|||||.||||.|.|.|.|.|||||||||...|.....|.|.         ||||.||||||||.||.
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM

NFN--RDAFLRIDVYACGLVLWEMVSRCDFAG------PVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWR-AHPGLNVFCDTMEECWDHDAE
||.  ..||.|.|.||.|||.||...|| ..|      .|.|.|.||..... .||... |. |..|..||.. | |. .||.....|.|||||||||.|
NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE

ARLSSSCVMERF
|||.. ||....
ARLTALCVKKTM
Kinase put.AA Type1 202-480 41 1.6e-114 311.5 In-house 1-283 (290) Show / Hide 
Range on Protein: 202-480
Range on HMM: 1-283/290
Sequence Identity: 41% (117 aa)

IQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHMDKP--EYWLISTYQHNGSLCDYLKSHTISWPELCR
||..|.  .||.|.||..|    .||||||   . .||  | .||    |||.||| | .          . |||. |  .||| |||..||..  ...|
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR

IAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPG---KPCGDTHGQVGTRRYMAPEVLEGAINFNR-DAFLRID
.| |.|.|||||| ||  ..  | || |||||.||||.. |.... ||||.|||  .|      . | .  .|||.||||||||.  .|.|  ... . |
LAYSCACGLAHLHMEIFGTQEFG-KPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIG-QNPRVGTKRYMAPEVLDETMNMNCFESYKMAD

VYACGLVLWEMVSRCDFAGPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDHDAEARLSS
.|. |||.||.  ||   | | ..|||.       || .. .. | ..||||   | | .|| ...    |.||| . ..||...
IYSFGLVMWEIARRCEVGGIVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTA
Kinase put.AA TKL 208-487 25 7.9e-93 314.7 In-house 1-364 (364) Show / Hide 
Range on Protein: 208-487
Range on HMM: 1-364/364
Sequence Identity: 25% (97 aa)

KASGRFGDVWQAKLNN----------QDVAVKIFRMQE-------------------------KESWTTEHDIYKLPRMR---HPNILEFLGVEKHMD--
  ||.|| |...|...          .|||||.|....                         . ||  .. .. .  |.   ||||. |.|. .  .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------KPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLT--------------
         .......  | ..|||..||      |. .||.| ..| |...|| ..| . |   || |.||| ||||.|.....|              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT---KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

ACIADFGLAMIFQPGKPCGD-----------------THGQVGTRRYMAPEVLEGAINFN-----------RDAFLRIDVYACGLVLWEMVSRCDFAGPV
..|.||||.  ... .   |                 |. |.|| |.||||||.|..|..           .... ..|||. |.||||...||      
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

GEFQ-LPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRA-------HPGLNVFCDTMEECWDHDAEARLSSSCVMERF
  .. .|.. ... .| ..| .. |. |.||| . . |.        .. .  ... |..|||||.|.|.| .....|.
-PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase put.AA Pkinase 202-487 20 4.2e-57 200.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 202-487
Range on HMM: 1-293/293
Sequence Identity: 20% (66 aa)

IQLLEQKASGRFGDVWQAKLNNQD--VAVKIFRMQEKESWTTEH-----DIYKLPRMRHPNILEFLGVEKHMDKPEYWLISTYQHNG----SLCDYLK--
......  || || |....  .    |||||.. ....||  ..      |. . |..||||......     |......  |  .|    .|.||..  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

-SHTI--SWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTA----CIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLE
 . ..  |. |.....  .. ||...|..           .| ||| |. |.|.... .     .|.|||||  |.   . . ... .||..||||||  
RHGCFYFSEWECKFYMYQILRGLEYCHSM-----------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV--

GAINFNRDAFLRIDVYACGLVLWEMVSRCDFAGPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGL-----------------NVFCD
  |.....   ..|...||..|.||...           .||  .    .. .. .. ..... .|   ...  ...                    ..|
--IRGGQYYGPKVDMWSCGCILYEMLCGR----------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

TMEECWDHDAEARLSSSCVMER--F
 .. |.. | . |..  ....   |
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase put.AA MLK 202-409 27 1.1e-34 117.81 In-house 1-232 (291) Show / Hide 
Range on Protein: 202-409
Range on HMM: 1-232/291
Sequence Identity: 27% (67 aa)

IQLLEQKASGRFGDVWQAKLNNQD-----VAVKIFR-------MQEKESWTTEHDIYKLPRMRHPN----ILEFLGVEKHMDKPEYWLISTYQHNGSLCD
||..|   || ||.|| ..  |.|     ||||..|         . |.|  | ....| ...|||    | .|.|| .    ... ... |  .|||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSLYN

YLKSHT---------------ISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKS------DLTACIADFGLAMIFQPGKPCGD
.|.. .               ..   . ..|  .|.|.. ||..        ... | ||| ||.|.|.        ..|. |.|||..  ..  . | .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM--------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH--QMC-T

-THGQVGTRRYMAPEVLE--GAINFNRDAFLRIDVYACGLVLWEMVSR
   .. || ..|||||..   .  ... .    ||.  |.|||||..|
NMMSNAGTYAWMAPEVIQQFRCEKYSEKC----DVWSWGVVLWEMLTR
Kinase put.AA S_TKc 202-488 20 1.1e-26 95.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 202-488
Range on HMM: 1-231/231
Sequence Identity: 20% (64 aa)

IQLLEQKASGRFGDVWQAKLNN--QDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHMDKPEYWLISTYQHN--GSLCDYLKSHT------
 ..|..  .| || |.... ..  . ||.|| .    |.   | .| |    .||||  ...|  .    .....  |  .  |.| ||.|..       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-ISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLEGAINFNRDA
 ..  . ....  ....|...|.          .  | ||| |  |.|| .  .  |.||||| ..         . ..||. |||||||          
PFPE-HARFYMYQICCALEYCHS----------H-GIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL-------GYG

FLRIDVYACGLVLWEMVS-RCDFAGPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDHDAEARLSSSCVME----
. ..|...|| .|.||.. .  |                        |. ...||..               ..| .. |.. | | |..   ...    
KCKCDWWSCGCILYEMLCGYPPFP-----------------------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD

----RFA
     . 
IKCHPWF
Kinase put.AA TK 202-381 13 1.2e-21 68.61 In-house 1-358 (486) Show / Hide 
Range on Protein: 202-381
Range on HMM: 1-358/486
Sequence Identity: 13% (49 aa)

IQLLEQKASGRFG---DVWQAKLNN---------------------------QDVAVKIFR---MQEKESWTT--------------EHDIYKLPR---M
|.|...  .| ||   .|.......                           ..||||. .    ...|                  |  . |. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNILEFLG-VEKHMDK---------PEYWLISTYQHNGS----LCDYLKSHT----------------------------------------------
.||||. ..| . ..  |         . ....  | ..|.    | |||...                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ISWPELCRIAESMANGLAHLHEE---IPASKTDGLKPSIAHRDFKSKNVLLKSDLT-----------AC
                               .. ..|. ..   |.|...||.              . . |||    |.|. ....           . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF--------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK

IADFGLA------MIFQPGK-PCGDTHGQVGTRR-------------------------YMAPEVLE
||||||.      .    ..     .... ||.|                         .||||.|.
IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLN
Kinase put.AA TKL-Unique 210-410 25 1.9e-20 68.97 In-house 7-225 (290) Show / Hide 
Range on Protein: 210-410
Range on HMM: 7-225/290
Sequence Identity: 25% (59 aa)

SGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYK----LPRMR-HPNILEFLGVEK--HMDKPEYWLISTYQHNGSLCDYLK-----------SHT
.| .| | ..| .  .||.|.|  .|. | . . . ..    . . . ||||. . |. .    . |.. ... |   ||| |.|            ...
EGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCK

ISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSD-----LTACIADFGLAMIFQ--PGKPCGDT-----HGQVGTRRYMAPEV
...    ..|. .| |. .|| ..|        | |.||| ||.|.|. ..     . . |.||||. .      .. .        . .|. |.|||||
LNMQQRVKMAIDIAQGMYYLHHCEP--------P-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

LEGA-INFNRDAFLRIDVYACGLVLWEMVSRC
|..    ...     .|||. | ||||...|.
LRMNFCQYSE----KSDVYSFGIVLWEIATRK
Kinase put.AA STE 202-407 19 1.4e-19 65.94 In-house 1-262 (359) Show / Hide 
Range on Protein: 202-407
Range on HMM: 1-262/359
Sequence Identity: 19% (56 aa)

IQLLEQKASGRFGDVWQAKLNNQD-----------------VAVKIFRMQEK-----------------ESWT---TEHDIYKLPR-MRHPNILEFLGVE
 ...|.  .| || | .|. ....                 .|.|. .....                 | .     | .| |  . | |||| ...| .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

KHMDKP-----EYWLISTYQHNGSLCDYLKS---------------HTISWPELCRIAESMANG-LAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSD
 . ...     | |..  |  .||| | .|.               |... .....|. .   | |..||.             | ||| |. |.||   
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-----------IIHRDIKPANILL---

LTACIADFGLAMIFQP---GKPCGD--------THG-----QVGTRRYMAPEVLEGAINF-NRDAFLRIDVYACGLVLWEMV
  . ..|||.. ....   ..            | .      |||  .|||||...  .  . .   . |..  |....||.
--VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase put.AA Dicty4 288-407 32 6.5e-18 56.5 In-house 102-211 (277) Show / Hide 
Range on Protein: 288-407
Range on HMM: 102-211/277
Sequence Identity: 32% (40 aa)

KSHTISWPELCR---IAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGD-THGQVGTRRYMAPEVLEGA
.| ...||   |   .| . | |...||. .|          | ||| || | |   .... ..||||. ......  .| . ...||  .|||||. . 
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV---------IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ

INFNRDAFLRIDVYACGLVLWEMV
  .|  |    |||  |.||||..
-PYNEKA----DVYSFGIVLWEIL
Kinase put.AA IRAK 210-408 28 6.2e-17 56.68 In-house 9-219 (317) Show / Hide 
Range on Protein: 210-408
Range on HMM: 9-219/317
Sequence Identity: 28% (63 aa)

SGRFGDVWQAKLNNQD--VAVKIFRMQEKESWTTEHDIYKLP---------RMRHPNILEFLGVEKHMDKPEYWLISTYQHNGSLCDYLKSHT-------
.| ||.| .....|..  .||| . ...... ..||..  .          | |||||....|     . ... |.  |  |||| | |  ..       
EGGFGCVYRGQWKNTTGIYAVKKL-KEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGY--CTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKP

ISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMI--FQPGKPCGDT-----HGQVGTRRYMAPEVLEGAI
 ||.  | |..  |.|. .||.  |.        .| |.| || |.||  ..|. |.||||.    . ..|  .       .  .||  ||.||    .|
LSWHQRCSICWGTACGIQFLHQNHPCT-------PIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPE----FI

N-FNRDAFLRIDVYACGLVLWEMVS
.   .    . ||| .|.|| | ..
RDPQGQLTKKTDVYSFGIVLLEVLT
Kinase put.AA TyrKc 202-487 22 7.1e-16 33.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 202-487
Range on HMM: 1-280/280
Sequence Identity: 22% (72 aa)

IQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRM--RHPNILEFLGVEKH-----MDKPEYWLISTYQHNGSLCDYLKSHT--I
|.|...  .| || |...... ..||||  .   .|    |  .  . .   .||||. ..||  .     |  . ....  |  .|.| |||..|   .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMRE--ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

SWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPG------KPCGDTHGQVGTR-----RYMAPEVLE
....|. ..   |.| ..||.             . |||    |.|.....|. |.||||.     .      |   .. .  |..     | ||||.. 
CMKDLLSFCWQIACGMEYLHSK-----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

GAINFNRDAFLRI-----DVYACGLVLWEMVSRCDFAGPVGEFQLPFEA-ELGLRPSLDEVQESVVMKKLRPRLLN-----SWRAHPGLNVFCDTMEECW
         . ..     ||.. | ..||. ...         | | .  ..    | .|| | |   . .|.  |     .   .    ..   |..||
---------NYGKFTTKSDVWSFGVCMWEIFTYG---------QQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQ-IMKQCW

DHDAEARLSSSCVMERF
..|.| | . | . |.|
HEDPEDRPTFSEIHECF
Kinase put.AA Pkinase_Tyr 202-313 23 1.6e-11 39.63 Pfam 1-129 (270) Show / Hide 
Range on Protein: 202-313
Range on HMM: 1-129/270
Sequence Identity: 23% (31 aa)

IQLLEQKASGRFGDVWQAKLN------NQDVAVKIFRM----QE--KESWTTEHDIYKLPRM-RHPNILEFLGVEKHMDKP-EYWLISTYQHNGSLCDYL
|.....  .| ||.|......      ...||||. .     ..  .|.   |  | |   . .||||. ..||  . ..| .....  |  .|.| |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMK--QLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KSH-----TISWPELCRIAESMANGLAHLHE
..|      .. ..|. ..   |.|...|..
RKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase put.AA Pkinase_Tyr 329-353 44 0.000835 13.51 Pfam 134-158 (270) Show / Hide 
Range on Protein: 329-353
Range on HMM: 134-158/270
Sequence Identity: 44% (11 aa)

HRDFKSKNVLLKSDLTACIADFGLA
|||   .|.|....... |.|||||
HRDLAARNCLVTENNVVKICDFGLA
Kinase put.AA TK 466-487 36 0.020847 3.02 In-house 465-486 (486) Show / Hide 
Range on Protein: 466-487
Range on HMM: 465-486/486
Sequence Identity: 36% (8 aa)

MEECWDHDAEARLSSSCVMERF
| .||..|.| | . | . |..
MQQCWHYDPEDRPTFSQLHEQL
Kinase put.AA MLK 466-487 27 0.093964 2.02 In-house 270-291 (291) Show / Hide 
Range on Protein: 466-487
Range on HMM: 270-291/291
Sequence Identity: 27% (6 aa)

MEECWDHDAEARLSSSCVMERF
|..||. |.. | |.. ... .
MKQCWNQDPHKRPSFRQIVQHL
Kinase put.AA Dicty4 252-261 70 0.237952 0.46 In-house 56-65 (277) Show / Hide 
Range on Protein: 252-261
Range on HMM: 56-65/277
Sequence Identity: 70% (7 aa)

RHPNILEFLG
|||||. |.|
RHPNICLFMG
Kinase put.AA Pkinase_Tyr 466-487 36 1.570287 2.42 Pfam 249-270 (270) Show / Hide 
Range on Protein: 466-487
Range on HMM: 249-270/270
Sequence Identity: 36% (8 aa)

MEECWDHDAEARLSSSCVMERF
| .||..|.| | . | . |..
MKQCWHYDPEDRPTFSEIHEQL