Gene BMX (Mouse)
BMX
Sequence
Protein domains of BMX.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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BTK | BMX.AA | BTK | 117-153 | 51 | 1.1e-22 | 82.58 | SMART | 1-37 (37) | Show / Hide |
Range on Protein: 117-153 Range on HMM: 1-37/37 Sequence Identity: 51% (19 aa) NPHLLIKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY |.|...|||..|..||..|||||.||.||||...... NNHRMQKYHPCFWMDGHWLCCQQTCKNAPGCCPCHPH |
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PH | BMX.AA | PH | 9-115 | 29 | 1.3e-19 | 73.41 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 9-115 Range on HMM: 1-92/92 Sequence Identity: 29% (32 aa) SILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDG-LLYVYASNEESRCQWL |.| |.||. . ..|.| |||. . |.||. || . |||| ........ .. .|.. |||.. |. .|..|..||.. .|. VIKEGWLHKKG------KRKSWKKRWFVLFNNCLYYYKDDK---YRPKGSIPLSDCQVTKVPDN------KRPHCFQIRT-DRRTYYFQAESEEEMNDWM KALQKEIR .|.|. .| QAIQSACR |
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PH | BMX.AA | PH | 9-117 | 28 | 3.9e-19 | 70.82 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 9-117 Range on HMM: 1-82/82 Sequence Identity: 28% (31 aa) SILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRCQWLK |.| |.||| ..|.| |||. .|.||. . . |||| .......| . |.|.. |. .|.....||.. .|.. VIKEGWLYKKS-------K-RWKKRWFVLFNDCLYYYKDK-----KPKGSIPLSDCTVRE-P------------CFEIHH-DRTYYFQCESEEEMQEWMQ ALQKEIRGN |.|| |. | AIQKAIHNN |
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BTK | BMX.AA | BTK | 122-153 | 40 | 5.7e-14 | 57.53 | Pfam | 1-32 (32) | Show / Hide |
Range on Protein: 122-153 Range on HMM: 1-32/32 Sequence Identity: 40% (13 aa) IKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY .||| .|...|...||.|..| ||||...... QKYHPCFWMNGHWSCCHQTDKNAPGCQPCHHW |
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SH2 | BMX.AA | SH2 | 274-363 | 37 | 5.7e-33 | 116.77 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 274-363 Range on HMM: 1-87/87 Sequence Identity: 37% (35 aa) YDWFAGNISRSQSEQLLRQK-GKEGAFMVRNSSQ-MGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAE--NYCFDSIPKLIHYHQHNSAG . |. |||||.. ||||.. ...|.|.|| |.. | |..|...| | ||||....|...| |..| ...|.|. |....|||. | QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
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SH2 | BMX.AA | SH2 | 276-357 | 29 | 2.3e-32 | 96.86 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 276-357 Range on HMM: 1-81/81 Sequence Identity: 29% (25 aa) WFAGNISRSQSEQLLRQ-KGKEGAFMVRNSS-QMGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYH |. |.|||.. |.||.. ...|.|.|| |. . | ||.|.. . ||||....... ..|.... .|.|.. |.... WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP---GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY |
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Kinase | BMX.AA | Tec | 397-648 | 72 | 6.6e-211 | 706.95 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 397-648 Range on HMM: 1-254/254 Sequence Identity: 72% (184 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQ--LL .|..||||.||||||.||.|..|||||.||||||.|||..|..||..||||||||||..|||||...||||||||...|||||||..|........ || LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL EMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYD |||.|||||||.||.|.|||||||||||||... |||||||||||||||||.|||||||||||..||||||..|||||||||||.|||||||.||.||. EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE LYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEP ..||||| .||||||||||.|.|..||||||.|||| ||.||||||||..|.. NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE |
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Kinase | BMX.AA | Pkinase_Tyr | 397-646 | 45 | 1.7e-146 | 496.76 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-270/270 Sequence Identity: 45% (124 aa) ITLLKELGNGQFGVVQLGQWK-----GQYDVAVKMIKEGAMSE----DEFFQEAQTMMKL-SHPKLVKFYGVCS-KKYP--IYIVTEYITNGCLLNYLKS ||..|.|| |.||.| .| || ....|||||.|||||.| ..|..||..|..| .||..|..||||. .. | ||||.|| .|.||.||.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK H---GKGLESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYV-LDDQY-VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAF | .. | .||.||.....||..|||...||||||||||||.... ||..|||..|.. ||.| ... |.|.|.|| |||...| |...|||||.| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF GILMWEVFSLGKQP-YDLYDNSEVVVKV-SQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAI |.||||.|..|.|| | .|.||. .. .|.|. .|....| ||..| .|||. ||.||||..... . GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | BMX.AA | TyrKc | 397-646 | 42 | 3.9e-134 | 452.83 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-280/280 Sequence Identity: 42% (121 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKL--SHPKLVKFYGVCSKK-------YPIYIVTEYITNGCLLNYLKSHGKG |||.|.||.|.||.| .|.|| ..|||||.||.| . .| .||. |.|| .|| .|..||||... |..||.|| .|.|..||..|.. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK LESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDD-------QYVSS---VGTK--FPVKWSAPEVFHYFKYSSKSDV | .||..|.....||..|.|...||||||||||||.... ||.||||..|.. || .| .. |.| .|..| |||.. | |...|||| LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV WAFGILMWEVFSLGKQPYDL-----YDNSEVVVKVSQGHRLYRPQL--------ASDTIYQIMYSCWHELPEKRPTFQQLLSAI |.||..|||.|..|.||| .|.||. .| ||.|. .|. ..| .|||| .|||| ||.||||... . . WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | BMX.AA | Src | 397-646 | 49 | 1.7e-120 | 406.63 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-255/255 Sequence Identity: 49% (127 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLK--SHGKGLESCQLL |.|...||.|||| | | |.|. .|||| .|.| || . | ||||.| ||.|.|||. | |||.. |||||||| ..|.|| ||| . |. |. ||. IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI EMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVL--DDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQP .| | ||||.||| ..||||||||| ||. .. .|| ||| | . || |... | |||.|| ||| ..| ... ||||| ||||..|... |. | DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP YDLYDNSEVVVKVSQGHRLYRPQLASDTIYQ-IMYSCWHELPEKRPTFQQLLSAI | .| ||. .|..| |. .|. | .|. || |||. ||.|||| | . YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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Kinase | BMX.AA | SFK-Src | 397-650 | 47 | 9.3e-120 | 356.75 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 397-650 Range on HMM: 1-259/259 Sequence Identity: 47% (123 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKS-HGKGLESCQLLE | | | || |||| | | | .. .|||| | ||||..|| |||| | || ||.|.. | || . ||||.|| . .| || ||.. ||..| || IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD MCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPY | .| |||.|| |.|||||||| || .|| |||| | . .|. | | |||.|| ||| . ..| |||||.||||| |. .| || MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY DLYDNSEVVVKVSQ--GHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLR . | ||. .| . | |. |. | |.|| || . |. |||| |. .| PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF |
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Kinase | BMX.AA | TK | 397-646 | 24 | 7.50000000001e-119 | 400.27 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-486/486 Sequence Identity: 24% (119 aa) ITLLKELGNGQFG---VVQLGQWKGQ--------------------------YDVAVKMIKEG-AMSEDEFFQ--------------EAQTMMKLS---- |||.|.|| |||| .| .|.|.|. .|||||.||| |||..|||. ||. |.... ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG -HPKLVKFYGVCSKK------------YPIYIVTEYITNGC----LLNYLKSHGKG-------------------------------------------- || .|..||||... |..||.|| .|. |..||... .. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------LESCQLLEMCYDVCEGMAFLESH------QFIHRDLAARNCLVDSDLS-----------VKVSDFGMT- | ||| ||.....||..|.|. .|.|||||||||||.... .|..|||.. DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR -------RYV-LDDQYVSSV------------------------GTKFPVKWSAPEVFH---------YFKYSSKSDVWAFGILMWEVFSLG-KQPYDLY |.. || |... |.|.|..| |||.. | |...|||||.||.||||.|..| ...| QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM DN---------SEVVVKVSQG--------------HRLYRPQLAS--------------DTIYQIMYSCWHELPEKRPTFQQLLSAI .| ||. .. .| .|. .|.... . .|..| .|||. ||.||||.||.... SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | BMX.AA | Src-Unclassified | 397-642 | 41 | 7e-102 | 344.77 | In-house | 1-280 (284) | Show / Hide |
Range on Protein: 397-642 Range on HMM: 1-280/284 Sequence Identity: 41% (117 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEG---AMSEDEFF--------QEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHG . ||..|| |||| | .| |.| ||||| ..| || | ||||.| |..|..||. |.|||. |.||.||| .|| || .|. | VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG KGLESCQLL-------------EMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLS-----VKVSDFGMT--RYVLDDQYVSSVGTKFPVKWSAPEVFH . . |.. . | || ||| . .|||||||| |. | ||| ||| . . || |. | .||.|| ||| | GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI YFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRP--QLASDTIYQ-IMYSCWHELPEKRPTFQQL | . | ||||| .||| ||.. .|. || .| ||. |. | |. .| .. | ||. || |||. |..|||| | YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTL |
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Kinase | BMX.AA | UTK | 397-646 | 32 | 8.6e-98 | 331.19 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-296/296 Sequence Identity: 32% (96 aa) ITLLKELGNGQFGVVQLGQWK------GQYDVAVKMIKEGAMSEDE------FFQEAQ---TMMKLS-HPKLVKFYGVCSKKYPIYIVTEYITNGCLLNY . |...|| |.||.|... .. .. ||||| ...|....| | ||. |.... ||......|||.. |..||||| || |..| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LKSHGKGLE-------SCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSD-------LSVKVSDFG---MTRYVL---------DDQYVSSVG-TK | .|.. .. ..|.|.|..|. .||..|.|..|.|||||||||||... ...|..||| |.|.| ...|. . . .. LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR FPVKWSAPEVFHYF-KYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQG--HRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAI |..| |||.. . ....|||||.||...||... |..|| . | .|.. |. | .|. .|. ....|..| .||| |..||.|..|.... WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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Kinase | BMX.AA | Fer | 397-647 | 34 | 2.9e-96 | 326.09 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 397-647 Range on HMM: 1-283/283 Sequence Identity: 34% (99 aa) ITLLKELGNGQFGVVQLGQ---------WKGQ--YDVAVKMIKEGAMSED---EFFQEAQTMMK-LSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYL .|| | ||.| || | .|. | . .|.||. |. ..... ||..||. |.. ..|| |||||||. . ||.|| |....|.|..|| VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL KSHGKG-LESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDS-DLSVK--VSDFGMTRYVLDDQYVSSVG---TKFPVKWSAPEVFHYFKYSSKSD | .. . ....|||... ||..|.|.. ||||.||||||.. .. .| .||||| | |..| .. . .| |..| |||.. .. ||.|.| KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD VWAFGILMWEVFSLGKQPYDL----YDNSEV-----VVKVSQGHRLYRPQLASDTIYQIMY-SCWHELPEKRPTFQQLLSAIE ||.||...||.|. |..|| . .| ... |... |. . ..|.||| .||.. ||.|||.... .. VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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Kinase | BMX.AA | TK-Unique | 397-646 | 31 | 2.1e-93 | 316.6 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-294/294 Sequence Identity: 31% (94 aa) ITLLKELGNGQFGVVQLGQWKG-------QYDVAVKMIKEGAMSED--EFFQEAQTMMKLS-HPKLVKFYGVCSKKY-PIYIVTEYITNGCLLNYLKSHG .......| |.|| | |. .| | ||||| |..| .| .|..|.| |..| || .|...|.| |. | .|. ||. .|.|..||.. . LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR KG-------------------------LESCQLLEMCYDVCEGMAFLES--HQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGT--KFPV .. . ...|. ..... ||..|.| ....||||.|||.|. .|. .|..||||.|.| ... .|. .. . |. PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI KWSAPEVFH--YFKY-SSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLA-SDTIYQIMYSCWHELPEKRPTFQQLLSAI .| |||.. . | ..|||||.||.||||.|.||..|| ....... .. .|.|. .|. |...|..|.|||.. ||.||.| |... . RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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Kinase | BMX.AA | Frk | 397-650 | 44 | 8.3e-93 | 314.63 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 397-650 Range on HMM: 1-260/260 Sequence Identity: 44% (116 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLK---SHGKGLESCQL | |...|| |||| | |.| . |||| .| |.| ..| .||| | || ||||.. | || . ||||.|| . .| |..||. .|. .. || IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL LEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTR-YVLDDQ--YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGK ..| | |||.|||. .||||||||| ||. ....|. |||. | . |.. | | .| .||.|| ||| .| |.. |||||.||||. |. |. VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR QPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLR || | ||. |..| |. .| ..|.|| |||. |.||||| | .| MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
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Kinase | BMX.AA | SrcB | 397-647 | 44 | 1.6e-91 | 309.84 | In-house | 1-251 (251) | Show / Hide |
Range on Protein: 397-647 Range on HMM: 1-251/251 Sequence Identity: 44% (111 aa) ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSH-GKGLESCQLLE . | | || |||| | .| .... |||| .|.|.|| . | .|| | .| | .||. | | .| ||||.|||. .|||| .||. | |. .|.. LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID MCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDL | . ||||..| . .||||| | | || |. |. |||. | . |. | | |||.|| ||| .. . |||||.||||. |. |. || MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG YDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIE |.||. ...| |. ||. . .|.|| ||.| || ||||. | | .. MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD |
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Kinase | BMX.AA | S_TKc | 397-649 | 26 | 6.5e-55 | 189.67 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 397-649 Range on HMM: 1-231/231 Sequence Identity: 26% (71 aa) ITLLKELGNGQFGVVQLGQWKG-QYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITN--GCLLNYLKSHGKG-----L ..|...| | ||.| ....|. . ||.|.|| . . .| | ..| || .||.|.|. .|.|.||. . | |. |.|..|.. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF ESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSS-KSDVWAFGILMWEVFS . ..| .|...... ||..||||| | |.|. .|..|||. | . . .|| . . ||||. .|. |.|.|..|....| .. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPW---YMAPEVL---GYGKCKCDWWSCGCILYEMLC LGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLS------AIEPL |. |.. . ... |. |. ... |.. |||||| ..| . . . -GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | BMX.AA | Pkinase | 397-646 | 23 | 3.6e-44 | 157.28 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 397-646 Range on HMM: 1-293/293 Sequence Identity: 23% (70 aa) ITLLKELGNGQFGVVQLGQWKGQYD-VAVKMIKEGAMSEDEFFQ-----EAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNG----CLLNYLK-SHG ..... .| | ||.| ....|| . |||| || .... . |.| | .|.|| |..|... | ||.|.|| .| | |.. . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KGL--ESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSV----KVSDFGMTR---YVLDDQYVSSVGTKFPVKWSAPEVFH-YFKYSSKSDV ... . .. ..| ...|.... |. .||||| |.|.|.. . |..||| . | . . . .|| . . |||| . .|..|.|. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVDM WAFGILMWEVFSLGKQPYD------LYDNSEVVVKVSQGHRLYRPQLAS---------------------DTIYQIMYSCWHELPEKRPTFQQLLSA--I |..|....|... |. |.. .. .... | .| .. . .. .....|.. |.||||..|.| . WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |