BMX

Species: Mouse
Alias: BMX, Bmx
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Tec

Sequence

Name Sequence Type Origin Length Description Download
BMX.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
BMX.AA Protein Sugen 655 None Fasta, JSON
BMX.NA RNA Sugen 3005 None Fasta, JSON

Protein domain

Protein domains of BMX.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BTK BMX.AA BTK 117-153 51 1.1e-22 82.58 SMART 1-37 (37) Show / Hide
Range on Protein: 117-153
Range on HMM: 1-37/37
Sequence Identity: 51% (19 aa)

NPHLLIKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY
|.|...|||..|..||..|||||.||.||||......
NNHRMQKYHPCFWMDGHWLCCQQTCKNAPGCCPCHPH

PH BMX.AA PH 9-115 29 1.3e-19 73.41 Pfam 1-92 (92) Show / Hide
Range on Protein: 9-115
Range on HMM: 1-92/92
Sequence Identity: 29% (32 aa)

SILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDG-LLYVYASNEESRCQWL
 |.|  |.||.      .  ..|.| |||. . |.||. ||    . |||| ........ ..       .|.. |||.. |.  .|..|..||.. .|.
VIKEGWLHKKG------KRKSWKKRWFVLFNNCLYYYKDDK---YRPKGSIPLSDCQVTKVPDN------KRPHCFQIRT-DRRTYYFQAESEEEMNDWM

KALQKEIR
.|.|. .|
QAIQSACR

PH BMX.AA PH 9-117 28 3.9e-19 70.82 SMART 1-82 (82) Show / Hide
Range on Protein: 9-117
Range on HMM: 1-82/82
Sequence Identity: 28% (31 aa)

SILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRCQWLK
 |.|  |.|||         ..|.| |||.  .|.||. .     . |||| .......| .             |.|.. |. .|.....||.. .|..
VIKEGWLYKKS-------K-RWKKRWFVLFNDCLYYYKDK-----KPKGSIPLSDCTVRE-P------------CFEIHH-DRTYYFQCESEEEMQEWMQ

ALQKEIRGN
|.|| |. |
AIQKAIHNN

BTK BMX.AA BTK 122-153 40 5.7e-14 57.53 Pfam 1-32 (32) Show / Hide
Range on Protein: 122-153
Range on HMM: 1-32/32
Sequence Identity: 40% (13 aa)

IKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAY
.||| .|...|...||.|..| ||||......
QKYHPCFWMNGHWSCCHQTDKNAPGCQPCHHW

SH2 BMX.AA SH2 274-363 37 5.7e-33 116.77 SMART 1-87 (87) Show / Hide
Range on Protein: 274-363
Range on HMM: 1-87/87
Sequence Identity: 37% (35 aa)

YDWFAGNISRSQSEQLLRQK-GKEGAFMVRNSSQ-MGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAE--NYCFDSIPKLIHYHQHNSAG
. |. |||||.. ||||..  ...|.|.|| |..  | |..|...|      | ||||....|...| |..|  ...|.|.  |....|||. |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

SH2 BMX.AA SH2 276-357 29 2.3e-32 96.86 Pfam 1-81 (81) Show / Hide
Range on Protein: 276-357
Range on HMM: 1-81/81
Sequence Identity: 29% (25 aa)

WFAGNISRSQSEQLLRQ-KGKEGAFMVRNSS-QMGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYH
|. |.|||.. |.||..  ...|.|.|| |. . | ||.|.. .        ||||....... ..|.... .|.|.. |....
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP---GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

Kinase BMX.AA Tec 397-648 72 6.6e-211 706.95 In-house 1-254 (254) Show / Hide
Range on Protein: 397-648
Range on HMM: 1-254/254
Sequence Identity: 72% (184 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQ--LL
.|..||||.||||||.||.|..|||||.||||||.|||..|..||..||||||||||..|||||...||||||||...|||||||..|........  ||
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

EMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYD
|||.|||||||.||.|.|||||||||||||...  |||||||||||||||||.|||||||||||..||||||..|||||||||||.|||||||.||.||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

LYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEP
 ..||||| .||||||||||.|.|..||||||.|||| ||.||||||||..|..
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE

Kinase BMX.AA Pkinase_Tyr 397-646 45 1.7e-146 496.76 Pfam 1-270 (270) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-270/270
Sequence Identity: 45% (124 aa)

ITLLKELGNGQFGVVQLGQWK-----GQYDVAVKMIKEGAMSE----DEFFQEAQTMMKL-SHPKLVKFYGVCS-KKYP--IYIVTEYITNGCLLNYLKS
||..|.|| |.||.| .| ||     ....|||||.|||||.|    ..|..||..|..| .||..|..||||. .. |  ||||.||  .|.||.||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H---GKGLESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYV-LDDQY-VSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAF
|   .. |   .||.||.....||..|||...||||||||||||.... ||..|||..|..  ||.| ... |.|.|.|| |||...| |...|||||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILMWEVFSLGKQP-YDLYDNSEVVVKV-SQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAI
|.||||.|..|.|| |   .|.||. ..  .|.|. .|....| ||..| .|||. ||.||||..... .
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase BMX.AA TyrKc 397-646 42 3.9e-134 452.83 SMART 1-280 (280) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-280/280
Sequence Identity: 42% (121 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKL--SHPKLVKFYGVCSKK-------YPIYIVTEYITNGCLLNYLKSHGKG
|||.|.||.|.||.| .|.||  ..|||||.||.|  . .| .||. |.||  .|| .|..||||...        |..||.||  .|.|..||..|.. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDD-------QYVSS---VGTK--FPVKWSAPEVFHYFKYSSKSDV
|   .||..|.....||..|.|...||||||||||||.... ||.||||..|.. ||       .| ..    |.|  .|..| |||.. | |...||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WAFGILMWEVFSLGKQPYDL-----YDNSEVVVKVSQGHRLYRPQL--------ASDTIYQIMYSCWHELPEKRPTFQQLLSAI
|.||..|||.|..|.|||        .|.||. .| ||.|. .|.         ..| .|||| .|||| ||.||||... . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase BMX.AA Src 397-646 49 1.7e-120 406.63 In-house 1-255 (255) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-255/255
Sequence Identity: 49% (127 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLK--SHGKGLESCQLL
|.|...||.|||| |  | |.|. .|||| .|.| || . | ||||.| ||.|.|||. | |||.. |||||||| ..|.|| |||  . |. |.  ||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

EMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVL--DDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQP
.|   | ||||.||| ..||||||||| ||. .. .|| |||  | .   || |... | |||.|| ||| ..| ... ||||| ||||..|... |. |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YDLYDNSEVVVKVSQGHRLYRPQLASDTIYQ-IMYSCWHELPEKRPTFQQLLSAI
|   .| ||. .|..| |. .|.   | .|. ||  |||. ||.||||  | .  
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase BMX.AA SFK-Src 397-650 47 9.3e-120 356.75 In-house 1-259 (259) Show / Hide
Range on Protein: 397-650
Range on HMM: 1-259/259
Sequence Identity: 47% (123 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKS-HGKGLESCQLLE
| | | || |||| |  | | .. .||||  | ||||..|| |||| | || ||.|.. | ||  . ||||.|| . .| || ||.. ||..|   ||  
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPY
|  .|  |||.||   |.|||||||| ||     .|| |||| | . .|.  |    | |||.|| |||   . ..| |||||.||||| |.  .|  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

DLYDNSEVVVKVSQ--GHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLR
.   | ||. .| .  | |.  |.   |  |.||  || . |. ||||  |.  .|   
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF

Kinase BMX.AA TK 397-646 24 7.50000000001e-119 400.27 In-house 1-486 (486) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-486/486
Sequence Identity: 24% (119 aa)

ITLLKELGNGQFG---VVQLGQWKGQ--------------------------YDVAVKMIKEG-AMSEDEFFQ--------------EAQTMMKLS----
|||.|.|| ||||   .| .|.|.|.                           .|||||.||| |||..|||.              ||. |....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPKLVKFYGVCSKK------------YPIYIVTEYITNGC----LLNYLKSHGKG--------------------------------------------
 || .|..||||...             |..||.||  .|.    |..||... ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LESCQLLEMCYDVCEGMAFLESH------QFIHRDLAARNCLVDSDLS-----------VKVSDFGMT-
                               |   ||| ||.....||..|.|.      .|.|||||||||||....            .|..|||.. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RYV-LDDQYVSSV------------------------GTKFPVKWSAPEVFH---------YFKYSSKSDVWAFGILMWEVFSLG-KQPYDLY
       |..  || |...                         |.|.|..| |||..          | |...|||||.||.||||.|..| ...|   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DN---------SEVVVKVSQG--------------HRLYRPQLAS--------------DTIYQIMYSCWHELPEKRPTFQQLLSAI
.|          ||. .. .|              .|. .|....              . .|..| .|||. ||.||||.||....
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase BMX.AA Src-Unclassified 397-642 41 7e-102 344.77 In-house 1-280 (284) Show / Hide
Range on Protein: 397-642
Range on HMM: 1-280/284
Sequence Identity: 41% (117 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEG---AMSEDEFF--------QEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHG
. ||..|| |||| | .| |.|  |||||  ..|    ||   |         ||||.| |..|..||. |.|||.  |.||.||| .|| || .|.  |
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

KGLESCQLL-------------EMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLS-----VKVSDFGMT--RYVLDDQYVSSVGTKFPVKWSAPEVFH
. .   |..              .   |  ||  ||| . .|||||||| |.    |     ||| |||    . . || |.   | .||.|| ||| | 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRP--QLASDTIYQ-IMYSCWHELPEKRPTFQQL
| . | ||||| .||| ||.. .|. ||   .| ||.  |. | |. .|  ..  | ||. ||  |||. |..||||  |
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTL

Kinase BMX.AA UTK 397-646 32 8.6e-98 331.19 In-house 1-296 (296) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-296/296
Sequence Identity: 32% (96 aa)

ITLLKELGNGQFGVVQLGQWK------GQYDVAVKMIKEGAMSEDE------FFQEAQ---TMMKLS-HPKLVKFYGVCSKKYPIYIVTEYITNGCLLNY
. |...|| |.||.|... ..      .. |||||  ...|....|      |  ||.    |.... ||......|||..  |..|||||  || |..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LKSHGKGLE-------SCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSD-------LSVKVSDFG---MTRYVL---------DDQYVSSVG-TK
| .|.. ..       ..|.|.|..|. .||..|.|..|.|||||||||||...       ...|..|||   |.|.|          ...|. . . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPVKWSAPEVFHYF-KYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQG--HRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAI
 |..| |||.. .  ....|||||.||...||... |..||  . | .|.. |. |  .|. .|.  ....|..| .|||  |..||.|..|....
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase BMX.AA Fer 397-647 34 2.9e-96 326.09 In-house 1-283 (283) Show / Hide
Range on Protein: 397-647
Range on HMM: 1-283/283
Sequence Identity: 34% (99 aa)

ITLLKELGNGQFGVVQLGQ---------WKGQ--YDVAVKMIKEGAMSED---EFFQEAQTMMK-LSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYL
.|| | ||.| || | .|.         |  .   .|.||. |. .....   ||..||. |.. ..||  |||||||. . ||.|| |....|.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KSHGKG-LESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDS-DLSVK--VSDFGMTRYVLDDQYVSSVG---TKFPVKWSAPEVFHYFKYSSKSD
|  ..  .   ....|||... ||..|.|.. ||||.||||||..  .. .|  .||||| |   |..| .. .   .| |..| |||.. .. ||.|.|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWAFGILMWEVFSLGKQPYDL----YDNSEV-----VVKVSQGHRLYRPQLASDTIYQIMY-SCWHELPEKRPTFQQLLSAIE
||.||...||.|. |..||        . .|      ...  |...  |. . ..|.|||  .||.. ||.|||....   ..
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK

Kinase BMX.AA TK-Unique 397-646 31 2.1e-93 316.6 In-house 1-294 (294) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-294/294
Sequence Identity: 31% (94 aa)

ITLLKELGNGQFGVVQLGQWKG-------QYDVAVKMIKEGAMSED--EFFQEAQTMMKLS-HPKLVKFYGVCSKKY-PIYIVTEYITNGCLLNYLKSHG
.......| |.|| |  |. .|       |  ||||| |..|  .|  .|..|.| |..|  || .|...|.| |.  | .|. ||. .|.|..||.. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

KG-------------------------LESCQLLEMCYDVCEGMAFLES--HQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGT--KFPV
..                         . ...|.  ..... ||..|.|  ....||||.|||.|. .|. .|..||||.|.| ... .|. ..  . |.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWSAPEVFH--YFKY-SSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLA-SDTIYQIMYSCWHELPEKRPTFQQLLSAI
.| |||..   .  | ..|||||.||.||||.|.||..||  ....... .. .|.|. .|.   |...|..|.|||.. ||.||.| |... .
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase BMX.AA Frk 397-650 44 8.3e-93 314.63 In-house 1-260 (260) Show / Hide
Range on Protein: 397-650
Range on HMM: 1-260/260
Sequence Identity: 44% (116 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLK---SHGKGLESCQL
| |...|| |||| |  |.|  .  |||| .| |.|  ..| .||| | || ||||.. | ||  . ||||.|| . .| |..||.    .|. ..  ||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

LEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTR-YVLDDQ--YVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGK
..|   |  |||.|||. .||||||||| ||. ....|. |||. |  . |..  | | .| .||.|| |||  .| |.. |||||.||||. |.   |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

QPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLR
 ||    | ||.  |..| |. .|     ..|.||  |||. |.|||||  |   .|   
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF

Kinase BMX.AA SrcB 397-647 44 1.6e-91 309.84 In-house 1-251 (251) Show / Hide
Range on Protein: 397-647
Range on HMM: 1-251/251
Sequence Identity: 44% (111 aa)

ITLLKELGNGQFGVVQLGQWKGQYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSH-GKGLESCQLLE
. | | || |||| | .| ....  |||| .|.|.|| . | .||  | .| | .||. | | .|  ||||.|||. .|||| .||.  |  |.  .|..
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDL
|   . ||||..| . .||||| | | ||   |. |. |||. | . |. |    | |||.|| |||  ..  .  |||||.||||. |.   |. ||  
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

YDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIE
  |.||.  ...| |. ||.   . .|.||  ||.| || ||||. | | ..
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD

Kinase BMX.AA S_TKc 397-649 26 6.5e-55 189.67 SMART 1-231 (231) Show / Hide
Range on Protein: 397-649
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

ITLLKELGNGQFGVVQLGQWKG-QYDVAVKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITN--GCLLNYLKSHGKG-----L
 ..|...| | ||.| ....|. .  ||.|.||      . . .| | ..|  || .||.|.|.     .|.|.||. .  | |. |.|..|..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

ESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSS-KSDVWAFGILMWEVFS
   .   ..| .|...... ||..|||||   | |.|.   .|..|||. | .      . .|| .   . ||||.   .|.  |.|.|..|....| ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPW---YMAPEVL---GYGKCKCDWWSCGCILYEMLC

LGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLS------AIEPL
 |. |..   . ... |.            |.   ...  |..  ||||||  ..|       . . .
-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase BMX.AA Pkinase 397-646 23 3.6e-44 157.28 Pfam 1-293 (293) Show / Hide
Range on Protein: 397-646
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

ITLLKELGNGQFGVVQLGQWKGQYD-VAVKMIKEGAMSEDEFFQ-----EAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNG----CLLNYLK-SHG
..... .| | ||.| ....||  . |||| ||    ....  .     |.| | .|.||  |..|...  |  ||.|.||  .|     |  |.. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KGL--ESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDSDLSV----KVSDFGMTR---YVLDDQYVSSVGTKFPVKWSAPEVFH-YFKYSSKSDV
...  .  ..  ..| ...|.... |. .|||||   |.|.|..  .    |..|||  .   |  .  . . .|| .   . ||||   . .|..|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVDM

WAFGILMWEVFSLGKQPYD------LYDNSEVVVKVSQGHRLYRPQLAS---------------------DTIYQIMYSCWHELPEKRPTFQQLLSA--I
|..|....|... |. |..        ..  ....   | .| ..   .                     ..  .....|..  |.||||..|.|    .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF