Gene caMLCK (Mouse)

caMLCK

Species: Mouse
Alias: caMLCK, D830007F02Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
caMLCK.NA RNA Sugen 3070 None Fasta, JSON
caMLCK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 256 Kinase domain by global Sugen HMM Fasta, JSON
caMLCK.AA Protein Sugen 795 None Fasta, JSON

Protein domain

Protein domains of caMLCK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase caMLCK.AA MLCK 491-746 64 4.3e-241 643.56 In-house 1-257 (257) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-257/257
Sequence Identity: 64% (166 aa)

VSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTELDVV
.. ||.||.|.||.||||.|.|||...|||.||..  ||.|.||||..||||| | ||||..||||.|.....||||..|||||.||.||..||||..|.
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI

LFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPREK-LKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFL
...||||||||..|...|.|||||||||.|...|.||||||||||||.|.|.|| .||.||||||.|||||||..|.|.|||||||||.||||||||||.
HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPFM

GETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|..|.||||.. .| |||| ..|.. |.|||||.||||||.|..||.|..||.|.||
GDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL
Kinase caMLCK.AA DAPK 493-746 46 2.3e-129 358.55 In-house 1-264 (264) Show / Hide 
Range on Protein: 493-746
Range on HMM: 1-264/264
Sequence Identity: 46% (123 aa)

QHEVLGGGRFGQVHRCTERSTGLALAAKIIKV-KNVKD-----REDVKNEVNIMNQLS-HVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITD-EKYHL
. | || |.|  | .|...|||.  ||| ||  .  ..     ||. . |..|  ... | |.| | ...| ..   || ||| |||||| .    . .|
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

TELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ--IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLL
.| |.. | .|| |||||||.  | ||||||.||.  .    |  ||||||||.|. .. | ..  .||||..|||.||||  |  |||||.|||||..|
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML

SGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|| |||||.|  ||   |  .. ||.  .|...||.||||  |||||.   ||.|..||.| |.
SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI
Kinase caMLCK.AA CAMK 496-746 25 6.9e-121 391.46 In-house 1-425 (425) Show / Hide 
Range on Protein: 496-746
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

VLGGGRFGQVHRCTERSTG------------LALAAKIIKVK----------------------------NVKDREDVKNEVNIMNQLS-------HVNL
.|| |.||.|..|....|.               |.|||. |                            . |||. |..|..||..|.       | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLYDAFES-------------------KSSFTLIM---EYVDGGEL----FDRITDEKY--------------HLTELDVVLFTRQICEGVHYLHQHYI
|.||...|.                   .. . ..|   ||..||||    ||.|.. ..              ..|| ..  . ||||..|||.|.| |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHLDLKPENILCVSQTG---------------HQIKIIDFGLARRYKP------------------------REKLKVNFGTPEFLA-PEVVNY------
 |.||||||||...  .               ..|||||||.|....|                         .|.|  .||||. | |||.|.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EFVSFPTDMWSVGVITYMLLSGLSPFLGE-------------TDAETMNFIVNCSWDFDADTFKG--------------------LSEEAKD
        . .....||||.|||.|..|.| .|| |.             .| |..  | .. .||. . |..                    .|.|.||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FVSRLLVKEKSCRMSATQCLKHEWL
.....|... . ||...|||.|.|.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase caMLCK.AA Trio 489-746 38 2.6e-115 297.03 In-house 1-258 (258) Show / Hide 
Range on Protein: 489-746
Range on HMM: 1-258/258
Sequence Identity: 38% (101 aa)

YTVSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTELD
||.  .| .| |||. |.||....||...|||.|  .  .|.| |  |  ..  |.|  ...| |..|.  .  || |  |.||| ...  ..  ..| .
YTF--QEEIGRGRFSVVRRCWHKATGRTCAAKFI-PYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLM-RWGSYCESE

VVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTG--HQIKIIDFGLARRYKPR--EKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSG
|  . .|. |.|||||.. |||||.||||.. .   .   ||||.||| |  . |   | .    |.||| |||... . ||  || ||.||.|| .|||
VKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSG

LSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
 |||..| | ||   |..   .|  ..|...|..||.|.  .|.   . | .| .|| | |.
ISPFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF
Kinase caMLCK.AA DAPK 492-746 48 1.1e-114 332.26 In-house 2-264 (264) Show / Hide 
Range on Protein: 492-746
Range on HMM: 2-264/264
Sequence Identity: 48% (127 aa)

SQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVK------DREDVKNEVNIMNQLS-HVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHL
 . | .| | |  | .|.|.|||.  ||| ||    .       |||.  ||.|  ... | | | | |..| |.   || | | |||||| .  || .|
DMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLC-EKECL

TELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ--IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLL
.|     |  || .|||..|   | |.|||||||        .  |||||||||.| .| .  |  |||||| |||.||||  .  |||||.||||| ||
NEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYILL

SGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|| |||||.|  ||.  |   . .||   ||  || ||||. |||||.   ||   .||.| | 
SGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI
Kinase caMLCK.AA CAMK1 489-746 36 8.4e-109 317.41 In-house 1-276 (276) Show / Hide 
Range on Protein: 489-746
Range on HMM: 1-276/276
Sequence Identity: 36% (103 aa)

YTVSQHEVLGGGRFGQVHRCTERST---GLALAAKIIK-VKNVKD-----REDVKNEVNIMN---QLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDR
| .  ....| | |..|..||...|   | . | |.|.  |..|      .| ..||..||    ...| | |..|. .||.. | |.||.| |||||||
YEF--GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

ITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQ-TGHQIK--IIDFGLARRYKPRE-KLKVNFGTPEFLAPEVVNY---EFVSFPT
| . . . || | ..  .||.. |.|.|.. | | ||||||.|....  ...||  |.||||...... | ..|  .|||.. ||||...   .. . . 
IVEKG-NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKAC

DMWSVGVITYMLLSGLSPFLGET-DAETMNFIVNCSWDFDADTFKGLSEE-AKDFVSRLLVKEKSCRMSATQCLKHEWL
||||.||||| || | .|| .|. |.| .  | .|...|. . .   |.. ||||.. .|... . | ...|||.| |.
DMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase caMLCK.AA S_TKc 491-746 33 4.1e-93 316.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

VSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDG--GELFDRITDEKYH-----
   ....| | ||.|..|....||   | ||||       |....|..|. .  | |...|||.|.. ... ..|||.||  |.|||.| . ..|     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSF-PTDMWSVGVITYMLL
..| ..  ...|||... |.|.| |.| ||||||||. .    .|||.||||||..      .   |||...||||.     .. . |.||.|.| | .|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLK-------HEWL
.|  ||   ....... |.              |.|||||....|.|. . |..| ..|.       |.|.
CGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase caMLCK.AA DRAK 493-746 39 9.2e-92 285.42 In-house 1-259 (259) Show / Hide 
Range on Protein: 493-746
Range on HMM: 1-259/259
Sequence Identity: 39% (102 aa)

QHEVLGGGRFGQVHRCTERSTGLALAAKIIKV-KNVKD-REDVKNEVNI-MNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFD-RITDEKYHLTELD
    .| |.|  | .| ...||   ||| .|  .  .| |.... |. . |.  .  ..| | . .| .|   |..||  |||.|.  . |.   ..| |
TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD

VVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ-IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSP
|.   ||| ||||||||  | |||||| |||  | .    |||.|||..|  .  | .    |||...|||. ||. ..  |||||.||.||..|...||
VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP

FLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|.|..  ||   |  |  |.  ..| ..|..| ||. .|.|..   ||.|..||.| ||
FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL
Kinase caMLCK.AA Ciliate-E2a 492-746 37 2.7e-86 254.01 In-house 2-275 (275) Show / Hide 
Range on Protein: 492-746
Range on HMM: 2-275/275
Sequence Identity: 37% (104 aa)

SQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDR---EDVKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTE-L
. . ..| | ||.|   . . ||   |.|... |.  .    | ..||.||| ||.| |.|.||. .|..... |.|||..||||.|.|   |   .|  
KFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQ

DVVLFTRQIC-EGVHYLHQHYILHLDLKPENILCV--SQTG---HQIKIIDFGLARRYKPREK--LKVNFGTPEFLAPEVVNYEFV------SFPTDMWS
..  . .|.  .|.||.||  |.| ||||||||    |...    .|||||||||..... ||  ...  ||| ..|||| |.. |      .   ||||
EICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWS

VGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADT-FKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
.||| | ||.| .|| |.| .|.   . .|  ||.    .. .| |.||.....|.|  . | .|.|.|.| | 
CGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase caMLCK.AA Pkinase 491-746 33 2.2e-83 288.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-293/293
Sequence Identity: 33% (98 aa)

VSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKN----EVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGG----ELFDRIT-DEK
   ....| | ||.| .|....||   | ||||... |. .|. .    |. ||. |.| | ..|||.||.|..  ..|||..||    .|||.|. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

YHL--TELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ---IKIIDFGLARR--YKPREKLKVNFGTPEFLAPEVVN-YEFVSFPTDMWS
  .  .| ..  . .||..|. |.|.. |.| ||||||||.. ..||    .||.|||||.   | . . ...  |||...||||.. ..  . . ||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGVITYMLLSGLSPFLGE------TDAETMNFIVNCSWDFDADTFKGLS-----------------EEAKDFVSRLLVKEKSCRMSATQCLKHEWL
.|.| | .|.|  || |.      .. . .. |  . ..|| ..    |                 ||.|||....| |  ..| .|.|.|.|.|.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase caMLCK.AA CDPK 491-746 36 8.7e-81 247.54 In-house 1-271 (271) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-271/271
Sequence Identity: 36% (99 aa)

VSQHEVLGGGRFGQVHRCTER-STGLAL-AAKIIKVKNVKDRED---VKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIME--YVDGGELFDRITDEKYH
   ..||| | |||| ..... .|.    | |||. ..||| |.   ..||..|. || | | |..|  .. .  . ..||  |. ||||||.|..... 
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH-

LTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGH-----QIKIIDFGLARRYKPR-----EKLKVNFGTPEFLAPEVVNYEFVSFPTDMWS
.|| .  .  |||   | | |.. | | ||||||||  |         .||.||.|.......      .|..  .|||  .|||| .        | ||
FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWS

VGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
 ||| | ||.|  || |..| |.|. . ..  .|. . ..  |.|||| ....|...   |||| |.|.| | 
CGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase caMLCK.AA Ciliate-E2 491-746 23 1.2e-74 254.31 In-house 1-365 (365) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

VSQHEVLGGGRFGQVHRCTERSTGLAL------------------AAKIIKVKNV--KDREDVKNEVNIMN----------------QLSHVNLIQLYDA
   ....| | ||.| .|. ....                     ..||. .|..  .. | .|.| .||.                ||.| |.|..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--SKSSFTLIMEYVDGGELFDRIT--DEKY--------HLTELDVVLFTRQICE---------------GVHYLHQHY-ILHLDLKPENILCVSQTGH
|.  ..... |.|||..||.|||.|   . |          .||  .  ...||..               ...|||.   |.| |.||||||       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

QIKIIDFGLARRYKPR----------EKLKVNF-----------------------GTPEFLAPEVVNYEF---------VSFPTDMWSVGVITYMLLSG
 ||||||||...|..           ....  .                       |||...|||..|..           ..  |.||.||| |..|.|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

LSPFLGETDAETMNFIVNCSWDFDAD--------------TFKGLSEEAKDFVSR----LLVKEKSCRMS-ATQCLKHEWL
  ||        .. | .| .||.                 .| .|.|.||. ..    .|.|. . |.. . |.|.|.|.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase caMLCK.AA Pkinase_Tyr 491-637 31 1.1e-21 74.09 Pfam 1-159 (270) Show / Hide 
Range on Protein: 491-637
Range on HMM: 1-159/270
Sequence Identity: 31% (51 aa)

VSQHEVLGGGRFGQVHRCTER----STGLALAAKIIKVKNVKD---REDVKNEVNIMNQL-SHVNLIQLYDAFE-SKSS--FTLIMEYVDGGELFDRITD
..  ..|| | ||.|...| .    .|..  | |..| .  ..   |||  .|..|| || .| |...|| .    . .    ..|||. .| | |   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E---KYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLAR
    | .||  | . . .||..|  ||... . | ||   |.|  .  ....|| ||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLAR
Kinase caMLCK.AA TyrKc 491-746 23 2.9e-15 24.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

VSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKNEVNIMNQL--SHVNLIQLYDAFESK-------SSFTLIMEYVDGGELFDRITDEK
..  ..|| | ||.|...| .   .  | | .|      |||  .| .|| .|  .| |...|| .  ..           ..|||...| | |.. . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

YHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPR-------EKLKVNF--GTPE-----FLAPEVVNYEFVSF
 .|.  | . |  ||..|  |||.. . | ||   |.|  ..   ..|| ||||.|  .         .  ..    |.        .|||. ||   ..
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

PTDMWSVGVITY-MLLSGLSPFLG-----ETDAETMNFIVNCSWDFDADT-----FKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
 .| || ||  . ..  | .|  |      ...| .... .       .      | . ..|  .  ..    . ..| . ...  || .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF