Gene CRK7 (Mouse)

CRK7

Species: Mouse
Alias: CRK7, D11Ertd752e
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
CRK7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 294 Kinase domain by global Sugen HMM Fasta, JSON
CRK7.NA RNA Sugen 7669 None Fasta, JSON
CRK7.AA Protein Sugen 1484 None Fasta, JSON

Protein domain

Protein domains of CRK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CRK7.AA CRK7 723-1016 65 2.7e-243 814.52 In-house 1-343 (343) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-343/343
Sequence Identity: 65% (226 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNE---KEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
...|..|||||||||||||.|.|||.|||||||.|||   |||||||||||||||||| ||..||.||||||||||..|||.||.||.||||||||||||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LESG-LVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERY--------
|||. ..|||....|.|||||.||.|||||||||||||||||||.||.|..|.||||||||||||| .|||||.||||||||||||||||||        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------TPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLR
                              .|.||.||||||||||||||||||.| |.||||.|...||||.|..||.|.|||..||||||.||.||||
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

EEFS------FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
|||.      |.|...|||||.||.|||.||.|||..||.|..
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase CRK7.AA CDK 723-1016 42 6.8e-171 551.14 In-house 1-284 (284) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-284/284
Sequence Identity: 42% (138 aa)

FDIIGIIGEGTYGQVYKAKDKDTG-----ELVALKKVRLDN-----EKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDK--GAFYLVFE
....  |||||||.||||.||.||     ..|||||.|..|     |||||||||||||..|..| |. .|. ......|... .. |||    .|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQ-----IKLADFGLARLYNSE-----ESRPYTNKVITLWYRPP
||||||.....          ||..|.||..||.|||.....|||.|..|||.|| |.     .|.|||||||.....     ..|.||..|.|||||.|
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELLLGEERYT--PAIDVWSCGCILGELFT---KKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDH
|||||...|.  ..||.||.|||..|.||   .||.|. . |. ||..|.|.||.|.. .||.| |||..                         |||..
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNK

MLTLDPSKRCTAEQTLQSDFL
||..||.||..||| ||....
MLCYDPKKRISAEQALQHPYF
Kinase CRK7.AA CMGC 723-1016 26 4.5e-140 463.45 In-house 1-513 (513) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-513/513
Sequence Identity: 26% (137 aa)

FDIIGIIGEGTYGQVYKAKD--------------KDTGELVALKKVRLDN---------EKEGFPITAIREIKILRQL----------------VHQS-V
..||. |||||||.|||..|              ..|.|.||.||....          ||.||||.|.||||||..|                 |   .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNMKEIVTDKQDALDFKKDK-------GAFYLVFEYMDHDLMGLLES--------GLVHFSEDH------------IKSFM------KQLMEGLD--YCH
|....|...|... . ..||         .||||||||||| .....        . ...|| |            ||.||      .|. .||.  |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KKN--FLHRDIKCSNILLNNS--------------------GQIKLADFGLARLYNSE--------------------ESRPYTNKVITLWYRPPELLLG
...  ..|||.| .|||.|.                     |..|..|||||| |...                    ..||||. | |.|||.||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

EERYT---------PAIDVWSCGCILGELFTK--------KPIFQ-----------ANLELAQLELISRLCGSPC---------------PAVWPDVIKL
 ..||         ..||.||.|||..|..|.        ||.|.            . .. ||..| ...|.|.               .  ||..|||
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PYFNT-------------MK------------PKKQYRRRLREEFSF-----------------------------------IPSAALDLLDHMLTLDPS
|..|.             ..             ...... ... | .                                   ... |.|||. ||..||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRCTAEQTLQSDFL
|| |||| || ...
KRITAEQALQHPYF
Kinase CRK7.AA CDC2 723-1016 38 5.8e-118 364.26 In-house 1-301 (301) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-301/301
Sequence Identity: 38% (122 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEG--FPITAIREIKILRQLV-HQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
.  |  ||||||| |||.||..|...|||||.||..| ||  .| |||||| .|  |  |. .|  ....                |.||||.|.||  .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----------NKLYMVFEYLDMDLKKY

LESGLV---HFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYT--NKVITLWYRPPELLLGEERYTPAID
..  ..   |.... .||.|.|. .|...|| .  .|||.| .|||....|.||.|||||||  .   .|.||    |.|||||.||.|||..||. ..|
MDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG-IPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVD

VWSCGCILGEL---FTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPK---KQYRRRLRE-----EFSFIPSAALDLLDHMLTLDPSK
.|| |||. |.    ||||.|..  |  ||  | |  |.|    ||.| .||....  |.   .. .. .       ..|...  ..|||. || .||.|
MWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQK

RCTAEQTLQSDFL
| .|.. ||  ..
RISAKEALQHPYF
Kinase CRK7.AA CDK9 723-1016 42 5.9e-118 398.16 In-house 1-340 (340) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-340/340
Sequence Identity: 42% (145 aa)

FDIIGIIGEGTYG-----------QVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEY
.. .  || ||.|            |.||. | .. .||.||| ..|||||||||| ||||.| .| |  |||. ||   |  |    ||.  |||||..
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

MDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLY----NSEESRP-YTNKVITLWYRPPELLLGE
 .||| |||   .| ||  |||. |..|| || | |.   |||| |  |.|    |  ||||||||| .    |.   || ||| |.||||||||||||.
CEHDLAGLLSNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGD

ERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTM-------KPKKQYRR---RLREEFS-------------
  | |.||.|  |||. |. |  || | | |  || ||| ||||  |.||| . ... .|.|        || |.|.   |..                 
RNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFGK

-------FIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
            |..|.| .|..|| || .... |  |. 
NVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase CRK7.AA PITSLRE 723-1016 41 7.2e-116 391.24 In-house 1-295 (295) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-295/295
Sequence Identity: 41% (127 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLD--NEKEGFPITAIREIK-ILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGL
| ..  |.||||| ||.|||| |.| ||||.. ..   ||||||||..|||. ||. | |  .|| ||||          ...   |.|.||..||| .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIV--------MGSNMDKIYMVMEYVEHDLKSL

LESGL---VHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW
.|        |..  ||..| ||  | .. |..  .||| |.||.|....|. |..|||||| | |   .|||  |.||||| |||||| . |....|.|
MENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSP-IKPYTPCVVTLWYRAPELLLGCKKYSTPVDMW

SCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMK-PKKQYRRRLREEFS---FIPSAALDLLDHMLTLDPSKRCTAEQTLQ
| |||..|. |.||.|| . |. |.. |  . | |    ||.. .|| .. |.  ...    ||. |     |   ..|||  |||..| .| ||.. |.
SVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALK

SDFL
 .. 
HPWF
Kinase CRK7.AA CDK7 723-1016 38 7.6e-112 299.2 In-house 1-288 (288) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-288/288
Sequence Identity: 38% (114 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVR----LDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMG
...|  ||||... |||| |. ||. || ||..     .  | |   |||||||||. . |  |...  |   |             .|||..|| ||  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKS----------NIQLVFDFMDWDLEV

LLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
  .   . .   |||..|...  || |||.   ||||.|  | |.|  ||.|.||||||| | |   | || .|.| ||| |||| |   |....|.|| 
VIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPN-RIYTHQVVTRWYRAPELLFGARHYGTGVDMWSV

GCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQY-RRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
|||. ||    |..    .. ||. | .  | | .. ||.. ... ....|.   | |  ||. |.  .  .|||.  |.|..|.||.|. | |.... 
GCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase CRK7.AA CDK5 723-1016 40 1.3e-101 321.91 In-house 1-287 (287) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-287/287
Sequence Identity: 40% (120 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLE
.. .  ||||||| ||||..|.|.|.||||.||||.| || | |||||| .|. | |. .| .  .. ..|              ||||..| ||   ..
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKK-----------LTLVFEFCDQDLKKYMD

SGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI
|  .  . . ||||| ||. || .||... |||| |  | | |  |. ||||||||| .     | |.  |.|||||||  |.|   |.  ||.||||||
SCNGEMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAF-GIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCI

LGELF-TKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFN---TMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
. |.  . .| |  | .  || .| .. |.||   || . ||| ..   .  |. . .  . .      .  .|||  || ..| .| .|.. |.  . 
FAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CRK7.AA S_TKc 723-1016 28 9.1e-98 332.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH---DLMGL
..|. .||.|..|.|||...|.||..||.|...         ....|||.||..  |  .|.....  |           . .|.|.||.|.   ||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDY

LESGLVH-----FSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTP-AI
...   |     |.| |....|.|. ..|.|||.....|||.| .||||..  .||..||||||..        |  . |.||..||.|     |.. ..
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----GYGKCKC

DVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQ-
|.||||||| |... .| |.      |.... ...|                                    .. |.|.....|. ||.|| || . || 
DWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------SDFL
        ..
EWDIKCHPWF
Kinase CRK7.AA Pkinase 723-1016 32 1.1e-97 335.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-293/293
Sequence Identity: 32% (100 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIR--EIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH-----D
. |...||.|..|.|||...|.||..||.|......||.....|..|  ||.|.. | |  .| ......|          |.  |.|.||...     |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----------KDHIYMVMEYCEGGLYVMD

LMGLLE-SGLVHF--SEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQI----KLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEER
|. ... .    |  ||...|..|.|. .||.|||.....|||.| .|||..| |.|    |..|||||....   .. .|  . |.||..||...| . 
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

YTPAIDVWSCGCILGELFTKKPIFQAN----LELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKR
|.|..|.||||||| |.....|.|.        . |...| |  | | .  ||  .  .||.  .. .   . ...    ......|... .|..||.||
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKR

CTAEQTLQSDFL
.|||| ||....
PTAEQILQHPWF
Kinase CRK7.AA CDK10 723-1016 42 8.5e-95 321.24 In-house 1-285 (285) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-285/285
Sequence Identity: 42% (124 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLES
|. .  .|||||| ||.|.|  . |.|||||||.| ||.| || ..|||..| |. |. .|...|.|  ..  ||      . .|| .| . ||  ||. 
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQH--LD------SIFLVMQYCEQDLASLLDN

GLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCIL
    |.| ..|  | |.. || | |..  .|||.| ||.|.   | ||.||||||| | .   .| | |..||||| ||||||    | |||.|  ||||
MPQPFTETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMY-GVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCIL

GELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
|||  .||..  | |..|...|  | |.|  ..||   .||  .    |||    |.. | ..  . . ||. ..  .| || |||..|.| . 
GELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase CRK7.AA MAPK 723-1016 32 3.6e-82 279.29 In-house 1-328 (328) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-328/328
Sequence Identity: 32% (106 aa)

FDIIGIIGEGTYGQVYKAKDKD------TGELVALKKVRLDNEKEGFPITAIREIKILRQL-VHQSVVNMKEIVTDKQDALDFKKDK---GAFYLVFEYM
..|.  ||.| ||.| .|.||       .|. ||.||.    ... .   ..||||.|| .  |  ......| | ..   |  ...     .|.|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEM-Q-DDQNSLEEFNDIYIVMELM

DHDLMGLLESGLVHFSEDHIKSFMKQLMEG--LDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPY-------------TNKVITLWY
..||  ...|.  . |.|||..|| |.  |  | | |  | .|||.| ||||.|  .. |..||||||   .|.. ..             |  | | ||
ETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWY

RPPELLLG--EERYTPAIDVWSCGCILGELFT-KKPIFQANLELAQLELISRLCGSPCPAVWPDVI--KLP--YFNTMK-PKKQYRRRLREEFS----FI
| ||..|.    .|| |.|.||.|||..|. |  ||.|. .  . |..||  ..|.| . ..  .   . .  |.  .. ..|. .. ... |.      
RAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNA

PSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
 . |.|||. ||..||.|| |.|. ||  ..
NPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CRK7.AA Pkinase_Tyr 723-927 27 9.9e-21 70.84 Pfam 1-209 (270) Show / Hide 
Range on Protein: 723-927
Range on HMM: 1-209/270
Sequence Identity: 27% (62 aa)

FDIIGIIGEGTYGQVYKAKDK----DTGELVALKKVRLDNEKEGFPITA------IREIKILRQL-VHQSVVNMKEIVTDKQDALDFKKDKGA--FYLVF
  ..  .||| .|.|||.. |    .|.  || |...     ||    .      .||.||..||  |. .|..  ..|         ....    |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT---------DQGEPNQIYIVM

EYMDH-DLMGLLESG---LVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLY-NSEES-RPYTNKVITLWYRPPELL
||| | ||   | .      ...  .. ..  |  .|..| . ||. |||. . |.|.......| .||||||.  | ..  |  ..  .     .|| .
EYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECI

LGEERYTPAIDVWSCGCILGELFT
   . .| . |||| |  . |.||
NYGK-FTTKSDVWSFGVLMWEIFT
Kinase CRK7.AA TyrKc 723-1016 21 5.4e-15 19.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 723-1016
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQL--VHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH-DLMGL
   . ..||| .|.|||.. |   . || |... |          .||..|...|   |. .|..  ..|...    |    .  ..|.|||.| ||   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--F-MYIEPLMIVMEYMPHGDLKDY

LESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSE----ESRPYT------NKV--ITLWYRPPELLLGEE
| .   ... ..  ||. |  .| .| |.||. |||. . |.|... ...| .||||.|   ..    ||  |       ..   . .   .|| .  . 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

RYTPAIDVWSCGCILGELFTKKPIFQAN-----LELAQLELISRLC-GSPCPAV----WPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHML
..|.. |||| |  . |.||       .     .. ...    .     |.|.                               |   |..  ..     
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------FVCCPDEMYQIMKQCW

TLDPSKRCTAEQTLQSDFL
  ||..|.| ..    ...
HEDPEDRPTFSEI--HECF