Gene DMPK1 (Mouse)

DMPK1

Species: Mouse
Alias: DMPK1, Dm15
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: AGC
Family: DMPK
Subfamily: GEK

Sequence

Name Sequence Type Origin Length Description Download
DMPK1.NA RNA Sugen 2723 None Fasta, JSON
DMPK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 269 Kinase domain by global Sugen HMM Fasta, JSON
DMPK1.AA Protein Sugen 631 None Fasta, JSON

Protein domain

Protein domains of DMPK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DMPK1.AA DMPK 71-339 68 2.5e-288 724.01 In-house 1-270 (270) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-270/270
Sequence Identity: 68% (185 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||||||||||.|.||.||..|||..|||||.||||.|||| |..||.||||..|.|..|||||||.|||||||||.||||..|||||||.|....|||..
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYE
||||||||.|.||.|.|..|||||||||||.||||.|||.|||||||.|...||||||.||||||||.|||.|||.... | |.||||||||..||..||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNRDGMVRSKVAVGTPDYISPEVLQAMEDD-GKGRYGPECDWWSVGVCMYE

MFYGQTPFYADSTAETYAKIVHY-REHLSLPLADT-VVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFF
|.||.|||||||..||| ||... ..|||.|  .. .|.|||.|||. |||..| ||||.|..||..||||
MLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF
Kinase DMPK1.AA GEK 71-339 73 2.3e-198 665.3 In-house 1-269 (269) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-269/269
Sequence Identity: 73% (199 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||||||||||||.||||||||.|.|||||||.|||.||||.|..||||||||||.|||||||.||.||||||||||||.||||||||||||||..|.|..
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYE
|||||.||.||||||||.|.||||||||||.|||..||||||||||||....||||.| ||||||||.|||||||...|  .|.||||||||.|||..||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNKDGMVQSNVAVGTPDYISPEILQAMEDG--KGRYGPECDWWSLGVCMYE

MFYGQTPFYADSTAETYAKIVHYREHLSLPLADT--VVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFF
|.||.|||||.|..|||.||.....|...| ..|  .|.|||.|||| |.|..| ||||.|..||.|||||
MLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF
Kinase DMPK1.AA AGC 71-339 30 5.4e-166 433.21 In-house 1-395 (395) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-395/395
Sequence Identity: 30% (124 aa)

FEILKVIGRGAFSEVAVVKMK------QTGQVYAMKIMNKWD--------MLKRGEVSC-------FREERDVLVKGD----------RRWITQ-LHFAF
||.|||||.|.|..|  |..|      .||..||||...|..        |...  . .       ..|||..|.| .            .|.. ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDENY--LYLVMEY--------YVGGDLLTLLSKFGE----RIPAEMARFYLAE-------IVMAIDSVHR-LGYVHRD-IKPDNILLDRCGHIRLADFG
||...  ||.||||        |.||.. ..|...|     | . |.||||.||       ||.|... |. .|..||| .||.|||||. |||.|.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SCLKLQPDG-------------------------------------------------MVRSLVAVG--TPDYLSPEILQAVGGGPGAGSYGPECDWWA-
.| ..  ||                                                 ..|    .|  ||.|..||||           ||..||||. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----------YGKACDWWSF

-LGVFAYEMFYGQTPFYADS----------TAETYAKIVHYR----EHLSLP-------LADTVVPEEAQDLIRGLLC-PAEIRLGRG-------GAGDF
 ||.. ||| .|..|||.|.           .|.. || ..|    . . .|        .|  . .||.|||..|||   | ||| |       || . 
GLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEI

QKHPFF
..||.|
KNHPWF
Kinase DMPK1.AA CRIK 71-339 47 3.2e-127 407.78 In-house 1-272 (272) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-272/272
Sequence Identity: 47% (130 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||.  .||.| | .| ||  |||. .||||.| |  .| . .|| | ||||..      |..|| .||||.. |||.|||  ||||| |.. ..     .
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQAVGG-GPGAGSYGPECDWWALGVFAY
|||||||| ..|. |.|  |||||||||.|||.|| ||| ||||||  |.  ...| |.  ||||||  ||.||   |   . |.|| .|||| .|. ||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAKMNRNNHVNSKMPVGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAY

EMFYGQTPFYADSTAETYAKIVH------YREHLSLPLADTVVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFF
|| .|.|||  |. ..|| .|         .. || | .|  |  .. |||. |||    ||.  .      ||||
EMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFP-DDPKVSPNYRDLIQSLLCNQSKRLKYEQ---LCCHPFF
Kinase DMPK1.AA ROCK 71-339 51 1.6e-121 410.03 In-house 1-263 (263) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-263/263
Sequence Identity: 51% (138 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
|...|||||||| || .|. |.. .|||||...| .|.|| .   | ||||..      || |||.||||. |||.||.|  ||||  |.|..   .|  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNY--DVPEK

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYE
 |||| .|.|.|.|..| .|..|||.||||.|||. ||..||||| |.|.. .||||.  |||||||.|||.|.. |   . | || |||||. ||| ||
WARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNKNGMVRCDTAVGTPDYISPEVLKSQG---QDGEYGRECDWWSVGVFIYE

MFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFF
|  |.|||||||   ||.||.  .. |. |  |. . ..|.|||.  |  .| |||| |  | ..|.||
MLVGDTPFYADSLVGTYSKIMDHKNSLKFP-DDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQHKFF
Kinase DMPK1.AA S_TKc 71-339 33 8.1e-87 295.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-231/231
Sequence Identity: 33% (95 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVG--GDLLTLLSKFGER--
.|||..||.|||..|  .. | ||...|.||..            .| |...| | .  .| .|. .||| ..||.||||  |  |||.... | | .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGP-ECDWW
   .|  .||||...|. |..  |..| .|||.||.|||||.  || ..|||.. .|           .|||.|..||.|          .||. .||||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----------GYGKCKCDWW

ALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLLC-PAEIRLGRGGAGD----FQKHPFF
..|.  |||..|..||.    .... ||.               ..|| |.||..|.   | |..   |        .||.|
SCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DMPK1.AA NDR 71-215 53 6.2e-84 258.66 In-house 1-149 (350) Show / Hide 
Range on Protein: 71-215
Range on HMM: 1-149/350
Sequence Identity: 53% (80 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGD--RRWITQLHFAFQDENYLYLVMEYYVGGDLLT---LLSKFGE
|||.|.||.||| || .|..| ||..||||||.| .|... .|   | |||.... |   .|.. | ..|||..||||||||  |||. |   ||.|.. 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMD-

RIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG
  . ..|||| ||.|.||.|||..||.||||||||.|.|. ||| | |||
IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase DMPK1.AA RSK 74-339 36 1.1e-71 244.49 In-house 1-278 (278) Show / Hide 
Range on Protein: 74-339
Range on HMM: 1-278/278
Sequence Identity: 36% (104 aa)

LKVIGRGAFSEVAVVKMK---QTGQVYAMKIMNKWDMLKRGE-VSCFREERDVLVKGD-RRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGER--
||| |.|.. .| ... .   .|||.||||. .|  . .|   .   ..||..|        | .|| |||.| .|||.|||  ||.|.| |.| .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDR---CGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQ-AV-GGGPGAGSYGPECDW
.  . |.||.||||.|..  | .| .|||.||.|||.|     |||.| ||| | .. .|   .    ..| .|. ||.|  |  .||     ..  |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGG-----HDKACDW

WALGVFAYEMFYGQTPFYA---DSTAETYAKIVHYREHLSLPLA-DTVVPEEAQDLIRGLLC-PAEIRLG--RGGAGDFQKHPFF
| |||  |||. |..||..   .. .|. ..| . .  .||..  .  . .||.||||..|.   . |||  ...| . ..||.|
WSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DMPK1.AA AktR 71-339 33 3.5e-67 229.52 In-house 1-268 (268) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-268/268
Sequence Identity: 33% (93 aa)

FEILKVIGRGAFSEVAVVKMK-QTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV-KGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIP
|...|..|.|||..|  |. | .....||||.  | .. .|   .  . ||...  . .   | .||..||....|...|||. ||.|.. | |. ... 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHL-KKKKKFS

AEMARFYLAEIVMAIDSVHRL-GYVHRDIKPDNILLDRCGHIRLADFG-SC-LKLQ-PDGMVRSLVAVGTPDYLSPEILQA-VGGGPGAGSYGPECDWWA
 |.|||| |.|. |..  |     . ||.||.|||||  ||....||| |  ..    | . .|.  .||| |..||...  .|       ..  .||||
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSF--CGTPEYMAPEMITKKKG-------HNKSVDWWA

LGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVP-EEAQDLIR-GLLCPA-EIRLG--RGGAGDFQKHPFF
.|.| ||| .|..|||.... . . ||  ..  .. |  ... . ....|||  .|||   . |||  . |. .  .||.|
FGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFP--YPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase DMPK1.AA MAST 71-215 40 2.7e-59 179.51 In-house 1-147 (337) Show / Hide 
Range on Protein: 71-215
Range on HMM: 1-147/337
Sequence Identity: 40% (60 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQD--ENYLYLVMEYYVGGDLLTLLSKFGERIP
||..|.|..||.  |  || | |.. .|||..|. |....  |   . ||..|.  .  ..  .  .||   ..||..||||  |||  .||. .| . |
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

AEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG
 .||..|.||.| ...  |  | ||||.||||.|.|  ||| |.|||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase DMPK1.AA MAST 71-215 42 4.1e-58 185.78 In-house 1-144 (334) Show / Hide 
Range on Protein: 71-215
Range on HMM: 1-144/334
Sequence Identity: 42% (61 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||. |.|..||.  |  || | |.. .|||...| ||...  |.  . ||..|   .  ..  .  .|| .|||..|||| .|||. .||. .| . . .
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG-YFDEW

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG
||..|.||.|....  |. | ||||.||||.|.|  ||| |.|||
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase DMPK1.AA Pkinase 71-339 26 1.9e-56 198.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 71-339
Range on HMM: 1-293/293
Sequence Identity: 26% (82 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFR-EERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGG----DLLTLLS-KFG
..|...||.|.|..|   . | ||...|.||..| .  .  ... .|  |  .. . .   | .|. .|.|....|.||||  ||    || ...| . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ERI--PAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHI----RLADFGSCLK--LQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYG
 ..  . . ..||. .|. ...  |. | .|||.||.|||.|. |||    ...|||.. .  . ...   ..  .|||.|..||...      |.  ||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF--CGTPWYMAPEVIR------GGQYYG

PECDWWALGVFAYEMFYGQTPFYAD------STAETYAKIVHYREHLSLPLADT----------------VVPEEAQDLIRGLLCPAEIRLGRGGAGDFQ
|..|.|..|.  |||. |..||. .      .  . ...| . . | . |  ..                 ..||..|.|...||.   .  | .| .  
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK--RPTAEQIL

KHPFF
.||.|
QHPWF
Kinase DMPK1.AA NDR 231-339 38 1e-39 119.75 In-house 241-350 (350) Show / Hide 
Range on Protein: 231-339
Range on HMM: 241-350/350
Sequence Identity: 38% (45 aa)

AVGTPDYLSPEILQA-VGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTV----VPEEAQDLIRGLLC-PAEIR
.||||||. ||..|   |       |...|||| ||.  |||  |..||..|.. ||. || .... .  |. .      . .||.|||| |.|  .. |
TVGTPDYMAPEVFQQKTG-------YNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHR

LGRGG--AGDFQKHPFF
||..|  . ....||||
LGSHGKGVDEIKSHPFF
Kinase DMPK1.AA MAST 232-339 37 2.6e-32 95.53 In-house 229-337 (337) Show / Hide 
Range on Protein: 232-339
Range on HMM: 229-337/337
Sequence Identity: 37% (43 aa)

VGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAE-TYAKIVHYREHLSLPLA-----DTVVPEEAQDLIRGLLCPA-EIR
.|||||..||..       | |.||.  |||..|.  ||   | .|| .|.  | . ..|... .... |       |  ...||||||. || |    |
CGTPDYIAPEVIL------GQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKR

LGRGGAGDFQKHPFF
|| .|| .  .||||
LGANGADEIKQHPFF
Kinase DMPK1.AA MAST 232-339 36 1.7e-30 95.28 In-house 225-334 (334) Show / Hide 
Range on Protein: 232-339
Range on HMM: 225-334/334
Sequence Identity: 36% (42 aa)

VGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYR-EHLSLPLA-----DTVVPEEAQDLIRGLLCP-AEIR
.|||||..||..       | |..|.  |||..|.  || . | .||  |.. |....|....    ..|       |   ..||||||. || |  . |
CGTPDYIAPEVIL------GQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKR

LGRG-GAGDFQKHPFF
|| . || . ..||||
LGANNGADEVKQHPFF
Kinase DMPK1.AA S_TK_X 340-407 25 3.9e-11 44.23 SMART 1-79 (79) Show / Hide 
Range on Protein: 340-407
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

FGLDWEGLR----DSVPPFTPDFE----GATDTCNFDVVEDRLTAMVSGGGETLSDMQEDMPLGV------RLPFVGYSYCC
 |.||..|.       |||.|.      ..|||.|||  ... |.|      . . . . |          ..|| |..| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase DMPK1.AA TyrKc 71-333 18 8.9e-11 -48.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 71-333
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKG---DRRWITQLHFAFQDE------NYLYLVMEYYVGGDLLTLLS
 . .|..|.||| ||   ..|   .  | | ...        .  |..|  .. |        .  .  . |..        |..||||  .|||.  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPD-------GMVRSLVAVGTPD-----YLSPEILQAVGGG
| ..... .    .   |    .  |. ...|||.   |.|... .... .||| . ..  |        . |.    |. .      ..|| .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------

PGAGSYGPECDWWALGVFAYEMF-YGQTPFYA-----DSTAETYAKIVHY--REHLSLPLADTV----VPEEAQDLIRGLLCP--------AEIRLGRGG
   | . .. | |. ||  .|.| |||.| .       | .| .... .   ..    ..   .     |.|  ....             .||      
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------

AGDF
  .|
HECF
Kinase DMPK1.AA Pkinase_C 357-409 24 3.7e-09 35.54 Pfam 1-46 (46) Show / Hide 
Range on Protein: 357-409
Range on HMM: 1-46/46
Sequence Identity: 24% (13 aa)

DFEGATDTCNFDVVEDRLTAMVSGGGETLSDMQEDMPLGVRLPFVGYSYCCMA
  ...|||.|||. ... ..| .       .... |. |  .||.|..|.   
QVKSPTDTSNFDPEFTDEPPMDTP------PDWR-MSSGDQEPFRGFTYVNPD
DMPK_coil DMPK1.AA DMPK_coil 472-532 47 1.8e-31 110.4 Pfam 1-61 (61) Show / Hide 
Range on Protein: 472-532
Range on HMM: 1-61/61
Sequence Identity: 47% (29 aa)

QLQEALEEEVLTRQSLSRELEAIRTANQNFSSQLQEAEVRNRDLEAHVRQLQERMEMLQAP
.||.|||.|....||...||.....||..|...|||||..||.||....||...||||.|.
ELQSALEAEIRAKQSIHEELNKVKAANIQFECKLQEAEKKNRELEQEMEQLKKEMEMLRAR