Gene FER (Mouse)

FER

Species: Mouse
Alias: Fert2, FER
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
FER.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 254 Kinase domain by global Sugen HMM Fasta, JSON
FER.NA RNA Sugen 2969 None Fasta, JSON
FER.AA Protein Sugen 823 None Fasta, JSON

Protein domain

Protein domains of FER.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FCH FER.AA FCH 1-92 33 7.4e-30 106.43 SMART 1-103 (103) Show / Hide 
Range on Protein: 1-92
Range on HMM: 1-103/103
Sequence Identity: 33% (35 aa)

MGFGSDL--KNSQEAVLKLQDWELRLLETVKKFMALRIKSDKEYAYTLQNLCNQ-------VDKESTVQVNYVSNVS--KSWLLMIQQTEQLSRIMKTHA
|.|.. |  ... |..|..|.|.||..|...|||. |.|...||| .|. |..|       ... .... . .. .|  |||  |.|||.|.....|.|.
MCFWWELWCDDGHEVLLQRQKWGLRWCEDMMKFMRERAKIEEEYAKMLHKLSKQYFNKKGSCGDWRAHRMTHPEMGSLNKSWEVMLQQTDQMAKHHKQHS

EDL
|||
EDL
FCH FER.AA FCH 1-92 27 3.7e-22 79.87 Pfam 1-97 (97) Show / Hide 
Range on Protein: 1-92
Range on HMM: 1-97/97
Sequence Identity: 27% (27 aa)

MGFGSDL-K--NSQEAVLKLQDWELRLLETVKKFMALRIKSDKEYAYTLQNLCNQVDKESTVQVNYVSNV--SKSWLLMIQQTEQLSRIMKTHAEDL
|.|.||. .  .. ....| ........| ...|.. |.....|||  ||.||....|    .  |....  .|.|  |.|.|||.... ...||.|
MSFWSDDYWQWDGFKVLFKRMKQGIQWCEDFAQFFKERAEIEEEYAKKLQKLCKKWFKKKKGSSEYHGTLSSKKAWHQMLQETEQMAQQHQQFAENL
SH2 FER.AA SH2 461-532 41 1.5e-40 120.89 Pfam 1-81 (81) Show / Hide 
Range on Protein: 461-532
Range on HMM: 1-81/81
Sequence Identity: 41% (34 aa)

WYHGAIPRIEAQELLKQ----QGDFLVRESHGKPGEYVLSVYSDG---QRRHFIIQFVDN--LYRFEGTGFSNIPQLIDHH
|||| |.| ||..||..     |.||||||  .||.|.|||. ||   . .|..||. ||  .|..... |.....|..|.
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 FER.AA SH2 459-538 37 2.3e-32 114.74 SMART 1-87 (87) Show / Hide 
Range on Protein: 459-538
Range on HMM: 1-87/87
Sequence Identity: 37% (33 aa)

HDWYHGAIPRIEAQELLKQQ----GDFLVRESHGKPGEYVLSVYSDGQRRHFIIQFVD-NLYRFEG---TGFSNIPQLIDHHFNTKQV
. |||| |.| ||..|||..    ||||||.|  .||.||||| ..|. .|..|.  | . |....   . |... .|..|.  ....
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Pkinase_Tyr FER.AA Pkinase_Tyr 564-815 51 1.5e-156 530.78 Pfam 1-270 (270) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-270/270
Sequence Identity: 51% (138 aa)

VSLGELLGKGNFGEVYKGTLK-----DKTPVAIKTCKEDLPQEL--KIKFLQEAKILKQY-DHPNIVKLIGVCT-QRQP--VYIIMELVPGGDFLTFLRK
...|. ||.|.||||||||.|     .|.|||.|..||.  .|   . .|..||||.||. .|||||.|.|||| |..|  .||.||..|.|| |..|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---KDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQE-DGGVY-SSSGLKQIPIKWTAPEALNYGRYSSESDVWSF
.   |. |..|.|. .....|.|| |||||||||||||||||||.|||. ||.|||..|   . . |  ..|   .||||.|||..|||.....||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWETFSLGVCP-YPGMTNQQAREQV-ERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKEL
|.|.|| |..|  | ||||.|..  |.. |.|||| .|.|||.|. ..|..||.|.||.|| | ..| .|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
TyrKc FER.AA TyrKc 564-815 46 2.1e-150 506.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-280/280
Sequence Identity: 46% (133 aa)

VSLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQY--DHPNIVKLIGVCTQR-------QPVYIIMELVPGGDFLTFLRKRK
..||. || |.||||||||.|  ..||.|..|||     .  |..||.|....  .|||||.|.|||||        .|..|.||..|.|| . .|||..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

DELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGG--------VYSSS---GLKQ-IPIKWTAPEALNYGRYSSES
..|..|.|. |....|.|| ||.|||||||||||||||||||.| ||||||.||  . .        .|...   | |  .||.|.|||..|||.....|
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVWSFGILLWETFSLGVCPYPG-----MTNQQAREQVERGYRMSAPQN--------CPEEVFTIMMKCWDYKPENRPKFNDLHKEL
||||||...|| |..|  ||||     |.||...|.|..||||  |.|        ||.|...|| .||...||.|| |...|...
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase FER.AA Fer 564-816 42 9.69999999999e-143 480.5 In-house 1-283 (283) Show / Hide 
Range on Protein: 564-816
Range on HMM: 1-283/283
Sequence Identity: 42% (121 aa)

VSLGELLGKGNFGEVYKG--TLKDKT---------PVAIKTCKEDLPQEL-KIKFLQEAKILKQ-YDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFL
| ||. ||.|.|||||||  ||| |          .|. |.||......  ...|..||.|... |||||.||..|||...||..|.||...||.....|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RKRKDE-LKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGE-NNTLK--ISDFGMSRQEDGGVYSSS-G--LKQIPIKWTAPEALNYGRYSSESD
.| |.. .......|.....|.|| ||.||||||||.||||||... .. .|  |||||||||.....|... .  ....||.|.|||....| ||...|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSFGILLWETFSLGVCPYPG------MTNQ--QAREQVER-GYRMSAPQNCPEEVFTIMM-KCWDYKPENRPKFNDLHKELT
|||||...|| |. | .||||      |||.  |||..... ||.|  |...|.|.  ||| .||...||.||........| 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase FER.AA TK 564-815 26 2.9e-127 428.97 In-house 1-486 (486) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-486/486
Sequence Identity: 26% (128 aa)

VSLGELLGKGNFG---EVYKGTLKDK--------------------------TPVAIKTCKEDLPQELKI-------------KFLQEAKILKQYD----
. ||. ||.|.||   |||||.....                          ||||.|..||. ... .              .||.|| ..|. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNIVKLIGVCTQR------------QPVYIIMELVPGGD----FLTFLRKRKDE--------------------------------------------
 |||||.|.|||||             .|..|.||..|.||     ...|||....                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LKLKQLVRFSLDVAAGMLYLESK------NCIHRDLAARNCLVGENNT-----------LKISDFGMS-
                               | ..||. .....|.|| ||.||      |..|||||||||||||||.            ||.|||.| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RQED-GGVYSSSG------------------------LKQIPIKWTAPEALN---------YGRYSSESDVWSFGILLWETFSLG-VCPYPGM
       |  . .. | ...                          ..||.|.|||.||         ||.....|||||||.|.|| |..| . .|.||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------QQAREQVERG--------------YRMSAPQNCP--------------EEVFTIMMKCWDYKPENRPKFNDLHKEL
.|         |.  |...||              .|| .|..||              ||.. .|..||.|.|| || | .||..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase FER.AA Src 564-815 48 1.6e-119 403.38 In-house 1-255 (255) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-255/255
Sequence Identity: 48% (125 aa)

VSLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLR--KRKDELKLKQ
. | . ||.|.||||..|. ...|.||.|| |..        |||||.|.|. .|...|.|  ||.|  |.||. |.   |  |..|.  ..  .|.|.|
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQ

LVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGV
|. ..  ||.|| ||||.| ||||||||| ||||||  |. |||  |  . .  .|...    .|||||||||.||||..  ||||||||||.| .. | 
LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR

CPYPGMTNQQAREQVERGYRMSAPQNCPEEVFT-IMMKCWDYKPENRPKFNDLHKEL
.|||||||... .||||||||  |.|||.|..  ||..||. .|| || |  |.. |
VPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase FER.AA SFK-Src 564-811 47 4e-115 342.76 In-house 1-251 (259) Show / Hide 
Range on Protein: 564-811
Range on HMM: 1-251/259
Sequence Identity: 47% (121 aa)

VSLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRK-RKDELKLKQL
. | . || | ||.|.||.  ..| ||.|| |     .    ||||| ..|.  ||| ..|  |||   |.||| ||.  |  | .|.  .   |.. ||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSA--EEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQL

VRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQ-EDGGV-YSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVC
|    .||.|| ||| .| .|||||||| |||.||. |. ||||||  ..    |    .   ||||||||| |. |.|  |||||||||. |   .|  
VDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRI

PYPGMTNQQAREQVER--GYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDL
|||||||.    ||.|  |||| .|.|||.| . ||. ||  .|..|| |  |
PYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESL
Kinase FER.AA UTK 564-815 37 5.4e-114 385.02 In-house 1-296 (296) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-296/296
Sequence Identity: 37% (112 aa)

VSLGELLGKGNFGEVYKGTLKD------KTPVAIKTCKEDLP-QELKI---KFLQEAK---ILKQYD-HPNIVKLIGVCTQRQPVYIIMELVPGGDFLTF
| ||..||.|.||||.|.....      .  ||.|.|... . |  .    .|. ||.   ..|| . |||...|.||||| .| .|..|. ..|| ...
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRKRKDELK-------LKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGEN-------NTLKISDFG---MSRQED----------GGVYSSSGLKQ
||. ....        | |.. ...|.|.|| ||.|....|||||||||||...       .. ||.|||   |||.               | ... ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

IPIKWTAPEALNYG-RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERG--YRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKEL
.||.|.|||||... |... |||||||...||... |  |||||.|.|. .||..|  ||| .|. ||..|...|..|| | |..|| | || ...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase FER.AA TK-Unique 564-815 37 4.7e-106 358.64 In-house 1-294 (294) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-294/294
Sequence Identity: 37% (111 aa)

VSLGELLGKGNFGEVYKGTLK------DKT-PVAIKTCKEDLPQELKIKFLQEAKILKQYD-HPNIVKLIGVCTQRQ-PVYIIMELVPGGDFLTFLRKRK
. .|...|.|.||.|..|...      ||.  ||.|..|... .. | .||.|....|. . |||||...|.||  . |..|||| .|.|. ...||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

DE-------------------------LKLKQLVRFSLDVAAGMLYLES--KNCIHRDLAARNCLVGENNTLKISDFGMSR-QEDGGVYSSSGL-KQIPI
..                         ...|.|..|  ..| || ||.|  |...||||.|||.|..|....||.||||.|  ...||||...  . |||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPEALN--YGRY-SSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNC-PEEVFTIMMKCWDYKPENRPKFNDLHKEL
.| |||.|   .| | ...|||||||.|.|| |.|| |||||| . . .|....||||  |..| ..|.. .|  || ..|| || | .. ..|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase FER.AA SRM 565-816 49 1.1e-99 334.16 In-house 2-253 (253) Show / Hide 
Range on Protein: 565-816
Range on HMM: 2-253/253
Sequence Identity: 49% (125 aa)

SLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQE-LKIKFLQ-EAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKDE-LKLKQ
 |.  ||.| ||||. |  |.. .||||  | |   . .. . || | . .|.  |  |..|  ||.   ||||| || . |  . .||   .  |.. .
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRD---NLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPH

LVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCP
|. |   || || |||..| ||||||||| |||.||. |. |||. |     .|| |   .||.|||||||.||. ||  ||||||||||.| |. | ||
LLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCP

YPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKELT
||||||  .  |..|||||  |  || ||.  |..||   || || | ||   ||
YPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase FER.AA Csk 564-815 44 5.7e-97 328.46 In-house 1-251 (251) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-251/251
Sequence Identity: 44% (113 aa)

VSLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQ-PVYIIMELVPGGDFLTFLRKR-KDELKLKQ
. |||  |.|.|| |  |... .  ||.|  |.|    .  .|| ||..  |  ||| |.||||  . .  .||.|| .  |  . .|| | .  .. .|
LHLGECIGHGEFGDVMQGEYQNRK-VAVKCIKCDGNGMAQ-AFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQ

LVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVY-SSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVC
|  |..||..|| |||.|. .|||||||| || | .  |.|||| ...|  .   |.||   .||||||||||  ...|. |||||||||||| .| |  
LLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSG--KFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRV

PYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKEL
||| .  .   ..||.|||| ||  ||..|...| .||.  | .|| |  . . |
PYPRIPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL
Kinase FER.AA Eph 564-815 42 7e-97 326.0 In-house 1-264 (264) Show / Hide 
Range on Protein: 564-815
Range on HMM: 1-264/264
Sequence Identity: 42% (113 aa)

VSLGELLGKGNFGEVYKGTLKDK-----T---PVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKD
. . . .| | ||||..|.|| .     .   |||||| |.  .   .. || || |. |.|||||..| || |...|| |. |    |   .|||.. .
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHDG

ELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQ-EDGG----VYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGIL
...  |||     .|.|| || . | .|||||||| || .|   |.||||.||. || .    .| ..| | |||.||||||. |....| |||||.||.
QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGK-IPIRWTAPEAIAYRKFTSASDVWSYGIV

LWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKEL
.||  | |  ||  |.||   . .| |||  .| .|||  . .|..|| . ...||.|....  |
MWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase FER.AA Tec 564-817 43 1.3e-95 324.0 In-house 1-254 (254) Show / Hide 
Range on Protein: 564-817
Range on HMM: 1-254/254
Sequence Identity: 43% (112 aa)

VSLGELLGKGNFGEVYKGTLKDKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKDELKLKQ--
  . . ||.| || |  | .. .  ||||. ||    |    |..|||. .   ||. |.| |||.|..|.||. | .  |  | .||..| ... ..  
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSE--EDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAI

LVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQE-DGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVC
|    .||  || |||... |||||||||||||...  |.|||||.|   |    ||.| |  |.|| .|| ..| |||| ||||.||.| || ||.|  
LLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTK-FPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKM

PYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHKELTV
||. |.| .  |.| .|.|.  |. |......|| .||  ||| || |..| ...| 
PYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase FER.AA S_TKc 564-822 27 5.4e-59 203.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 564-822
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

VSLGELLGKGNFGEVYKGTLKD-KTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPG--GDFLTFLRKRKDE----
  .....||| ||.|||.. |. .  ||||  |        .....| .|||. .|||||||..|.   . .|..||...|  || .....||. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSS-ESDVWSFGILLWET
 .   .  ..   .. .. |. |.. |||||   | |. |  ..||.|||..||                 . ||| |    |.  ..|.||.|..|.| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDLHK--ELTVIKKMI
.. |  |.|  . |.  ...            ..|.  ...||... ||.||   .. .  ..  .   .
LC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FER.AA Pkinase 564-806 24 8.7e-46 162.98 Pfam 1-282 (293) Show / Hide 
Range on Protein: 564-806
Range on HMM: 1-282/293
Sequence Identity: 24% (70 aa)

VSLGELLGKGNFGEVYKGTLKDK-TPVAIKTCKEDLPQE--LKIKFL-QEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVPGG----DFLTFLR-KRK
  .|. .|.|.||.|||.. |.    ||.|. | .   .  ...... .|..|.|  .|||||.|..... .. .|..||...||    |  .... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DEL--KLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTL----KISDFGMSRQEDGGVYSSSGLKQIP---IKWTAPEALN-YGRYSSESDV
  .    ... .. . .. |. |. |...|||||   |.|. .|...    ||.||| ..| |   | ...  . .   . . ||| .. .  |....|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGILLWETFSLGVCPYPGM----TNQQAREQVERGYRMSAPQNCP-----------------------EEVFTIMMKCWDYKPENRP
||.|..|.| .. |  |.||     .    .. ..|  .   . ..|                       ||   .. .|....|. ||
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP