IKKa

Species: Mouse
Alias: IKKa, Chuk
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: IKK

Sequence

Name Sequence Type Origin Length Description Download
IKKa.AA Protein Sugen 745 None Fasta, JSON
IKKa.NA RNA Sugen 3500 None Fasta, JSON
IKKa.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 274 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of IKKa.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IKKa.AA IKK 15-288 44 3.4e-169 568.38 In-house 1-297 (297) Show / Hide
Range on Protein: 15-288
Range on HMM: 1-297/297
Sequence Identity: 44% (131 aa)

WEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLELSSKNRERWCHEIQIMKKLDHA-------NVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLL
|||..|||.|.|||| ...|.... |.|.|.|. ......|..||.|...||.|.|.       |....||..|.... |...|...||||.||||.|.|
WEMCDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSWMRCRWVWCREFEWMKRLNHQRQFVWFPNIWCLCDIEEDMQWQICKQPVIVMEYCTGGDLYKYL

NKPENCCGLKE-SQILSLLSDIGSGIRYLH-ENKIIHRDLKPENIVLQ-DVGGKTIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFE--------NK
|.|.||||||| ...|....|...|...|| .|.|.|||.||.||..| ...||||.||.|.|||...|......||.||..||.|...|        .|
NSPWNCCGLKEGHEFLQVCRDCCAGMHHLHSQNGIVHRDIKPGNIMCQKGEDGKTIYKITDFGYAREWDDDEMFMSFYGTEEYLHPDMYERAVLRKPHQK

PYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDP-----KCIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLMLNWDPQQRG
||.|||||||||.....|..|..||..|.||..||||.|....     .||...|||.|.|..||||||...||..|.|.||.|...||.|...|..
PYCATVDYWSFGVTFYHCATGELPFMPHWQPRRWHEKMKHITTEKPSGVCIGVQEEMNGPVEWSSHLPQYCHLCQIIHEQMEPWCIMMLEWHQDQCW

Kinase IKKa.AA S_TKc 15-301 27 1.3e-69 238.51 SMART 1-231 (231) Show / Hide
Range on Protein: 15-301
Range on HMM: 1-231/231
Sequence Identity: 27% (81 aa)

WEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLELSSKNRERWCHEIQIMKKLDHANVVKACDVPEELNFLINDVPLLAMEYCSG--GDLRKLLNKPEN
.|. . .| |.|| | . .|.. . . |||  .        |. . ||||.|| .| |.||  || ..      |   . ||||.|  |||.... |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGR

---CCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTA-TVDYWSFG
   .... | .. ...  | ... |.|...||||||||||| | .       ||.| | |. .      |.|.||. |.|||..   .|.   .| ||.|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

TMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLMLNWDPQQRGGPIDLTL-----KQPRCF
 ...|...|| ||    |...  .||.                                  ... . .. .|..||..| .  ..       |.   |
CILYEMLCGYPPFP---QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IKKa.AA Ciliate-E2 15-293 19 2.6e-49 167.42 In-house 1-359 (365) Show / Hide
Range on Protein: 15-293
Range on HMM: 1-359/365
Sequence Identity: 19% (78 aa)

WEMRERLGTGGFGNVSLYQHRELDLKIAIK-------------------SCRLELSSKNRERWCHEIQIMK----------------KLDHANVVKACDV
 .  . .|.|.|| | . .... . ..|||                        .. .. | .  ||.||.                .|.| |..|  ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

PE--ELNFLINDVPLLAMEYCSGGDLRKLLN---KPENCC-----GLKESQILSLLSDIGS---------------GIRYLHENK-IIHRDLKPENIVLQ
 .    | .      | ||||.||||.....   | .|..      ..| .|. .   | .               ...|||... |||||.|||||.. 
FQEKDDNNIY-----LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-

DVGGKTIHKIIDLGYAKDVDQG--------------------------------SLCTSFVGTLQYLAPELFENKP---------YTATVDYWSFGTMVF
        ||||.|..|..|.                                  .  ...||. |.||| ...|.         |.  .|.||.| . .
-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

ECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMTGEVRFSSHLPQPNSLCSLIVEPME--SW----------LQL----MLNWDPQQRGG-PIDL
|.. |..||                        . . ....|..  .| . .  .| .  .  ||          ..     ||. ||..| . . ..
EMLFGKPPF----------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

Kinase IKKa.AA ULK 15-221 30 1.6e-48 167.51 In-house 1-252 (324) Show / Hide
Range on Protein: 15-221
Range on HMM: 1-252/324
Sequence Identity: 30% (79 aa)

WEMRERLGTGGFGNVSLYQHRELDL-----KIAIKSCRLE-LSSKNRE--------RWCHEIQIMKKLD---HAN--VVKACDVPEEL--NFLINDVPLL
......|| | || |  |. |  .      ..|.|   .  .. |. |          . ||||||||.   | |  .||  |. |.   |..      .
YCLNHCLGKGSFG-VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIY-----I

AMEYCSGGDLRKLLNKPENC------CGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKT---------IHKIIDLGYAKDVDQG---
 |||| ||||.....|  ..        | |..... . .| .| ..||...|||||.||.|| . .  .||         . || | | || || .   
IMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

-SLCTSFV------GTLQYLAPELFE----NKPYT-ATVDYWSFGTMVFECIAGYRPF
  .|...|      ||  | ||....    .|||. . .| ||.|.. .|.. |. ||
QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF

Kinase IKKa.AA ULK 15-221 28 1.7e-46 160.3 In-house 1-256 (329) Show / Hide
Range on Protein: 15-221
Range on HMM: 1-256/329
Sequence Identity: 28% (76 aa)

WEMRERLGTGGFGNVSLYQHRELDL------KIAIKSCR---LELSSKNRE------RWCHEIQIMKKLD--------HANVVKACDVPEEL--NFLIND
......|| | ||    |. |  .       |.|.|      .  .....|        . ||.|||||.        | |.||  |. |.   | .   
YCLNHCLGKGSFG--KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIY--

VPLLAMEYCSGGDLRKLLN--KPENCCG-----LKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKT---------IHKIIDLGYAKDVD
   . |||| ||||.....  |... .      | |..... . .| .| ..||...|||||.||.|| . .  .||         . || | | || ||
---IIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVD

QG----SLCTSFV------GTLQYLAPELFE----NKPYT-ATVDYWSFGTMVFECIAGYRPF
 .     . ...|      ||  | ||....    .|||. ...| ||.|.. .|.. |. ||
NDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPF

Kinase IKKa.AA Pkinase 15-224 32 2.8e-45 161.16 Pfam 1-215 (293) Show / Hide
Range on Protein: 15-224
Range on HMM: 1-215/293
Sequence Identity: 32% (73 aa)

WEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLELSSKNRE---RWCHEIQIMKKLDHANVVKACDVPEELNFLINDVPLLAMEYCSGG----DLRKLL
..  ...| |.|| | . .|.    . |.|  ...  ... .   |.  ||||||.|.| |.|.  |. |.     .| . . |||| ||    ||  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

NKPENCCGL--KESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGK-TIHKIIDLGYAKD--VDQGSLCTSFVGTLQYLAPELFE-NKPYTAT
   .. ...   | .. . .  | .|. |.|...||||||||||| . . |   .. ||.| | ||      .| .|.|.||. |.|||.   ...|.  
ST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDYWSFGTMVFECIAGYRPFLHH
|| ||.| ...| . |. || .|
VDMWSCGCILYEMLCGRPPFPGH

Kinase IKKa.AA CAMKL 15-208 31 6.2e-45 141.24 In-house 1-223 (297) Show / Hide
Range on Protein: 15-208
Range on HMM: 1-223/297
Sequence Identity: 31% (71 aa)

WEMRERLGTGGFGNVSLYQHREL-DLKIAIKSCRLELSSKNRERWCH--------------EIQIMKKLD---HANVVKACDVPEELNF------LINDV
... . ||.|.|| | | .|. .   | |||    .  ...   ...              ||||||.|.   | |..|  .| |  ..      .    
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIY---

PLLAMEYCSGGD--LRKLLNKPENCC-GLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVD-Q----GSLCTSFV
  | |||||||.  |   . | ...   ..|..   .   | |.. |.|...|.|||.||||| | . |     |||| | .   . .    | ... | 
--LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFC

GTLQYLAPELFEN--KPYT-ATVDYWSFG
|.. | |||.|.   |||    || || |
GSPPYMAPEIFQGNNKPYDGPKVDIWSCG

Kinase IKKa.AA Ciliate-E2-Unclassified 15-221 23 2.2e-43 148.35 In-house 1-270 (352) Show / Hide
Range on Protein: 15-221
Range on HMM: 1-270/352
Sequence Identity: 23% (66 aa)

WEMRERLGTGGFGNVSLYQHRELD-------LKIAIKSCRLELSSKNRERWCHEIQIMKK------------------LDHANVVKACDVPEELNFLIND
 .. . .|.|||| | . ||.. .       .| ...  ..   .|. | .  ......|                  ..| ..|| ... .  . ..  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY--

VPLLAMEYCSGGDLRKLLNKPEN--------------CCGLKESQIL-----SLLSDIGSGIRYLHENK-IIHRDLKPENIVLQDVGGKTIHKIIDLGYA
   . |||| ||||.. ..| ..               . . | |..      ..  | .|. |||... |||||.|||||.... |..   ||||.| .
---IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

K--------DVDQG---------SLCTSFVGTLQYL----APELFENKPYTAT----VDYWSFGTMVFECIAGYRPF
|        | ...          ....|.||..|.    |||..... |  .    .|.||.|   .|.. ||.||
KKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPF

Kinase IKKa.AA CAMK 20-221 23 3.4e-43 136.57 In-house 1-334 (425) Show / Hide
Range on Protein: 20-221
Range on HMM: 1-334/425
Sequence Identity: 23% (78 aa)

RLGTGGFGNVSLYQHRELD------------LKIAIKS---CRLEL------------------------SSKNRERWCHEIQIMKK-------LDHANV
 ||.|.|| | | .|..               | |||     .|                          . |.|..  .||.||||       ||| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKACDVPEELNF------------LINDVP---LLAM---EYCSGG----DLRKLLNKPENC------------CGLKESQILSLLSDIGSGIRYLHENK
.|  .| |  ..             . . .    . |   ||||||    ||   . . ...              ..|..   .   | |...|.|...
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKPENIVLQDVGGKT--------------IHKIIDLGYAKDVDQ------------------------GSLCTSFVGTLQYLA-PELFEN-----
|.||||||||| |.| .. .                |||| | |. .|.                        | ... |.||. | | ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYTATVDYWSFGTMVFECIAGYRPF
         ..|.  .| || | . . .  || ||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF

Kinase IKKa.AA TKL 21-224 21 1.5e-35 124.45 In-house 1-292 (364) Show / Hide
Range on Protein: 21-224
Range on HMM: 1-292/364
Sequence Identity: 21% (64 aa)

LGTGGFGNVSLYQHRELD--------LKIAIKSCRLE--------------------------LSSKNRERWCHEIQIMKKLDHANVVK---ACDVPEEL
.| |||| |   ..|  .          .|.|  . .                           .|..|..   || .|..|.| |.|.   .|  |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

NFLINDV-----PLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENK--------IIHRDLKPENIVLQDVG-----------GKT
 . .. |     . . ||||.||.|. .|.          .|....  || .|. ||| ..        |||||||..|| . . .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

IHKIIDLGYAKDVDQ--GSLCTS------------------FVGTLQYLAPELFENK----------------PYTATVDYWSFGTMVFECIAGYRPFLH
  || |.| .....|  .. .|.                   .||....|||.....                .|.  .| .||| . .|.... ||. .
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

H
.
Y

Kinase IKKa.AA STE 93-213 28 1.2e-27 94.79 In-house 114-260 (359) Show / Hide
Range on Protein: 93-213
Range on HMM: 114-260/359
Sequence Identity: 28% (44 aa)

LAMEYCSGGDLRKLLN-KPENCCGLK----------ESQILSLLSDIGSG-IRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQ------
..|||..|| |..... | .  ..|.          ||||   . .|  |   |||...|||||.|| || |         |..| | .. ...      
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANIQ

-----------GSLCTSFVGTLQYLAPELFEN------KPYTATVDYWSFGTMVFE
           .. ...||||  . |||  ..      |.|.. .| ||.| .. |
SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIE

Kinase IKKa.AA NEK 95-208 33 4e-26 89.25 In-house 85-211 (286) Show / Hide
Range on Protein: 95-208
Range on HMM: 85-211/286
Sequence Identity: 33% (42 aa)

MEYCS-GGDLRKLLNKPENCC----GLKESQILSLLSDIGSGIRYLHEN-----KIIHRDLKPENIVLQDVGGK-TIHKIIDLGYAKDVDQG-SLCTS-F
||||  |||| ..... ...      . |.||.  .  . ....|.|..     ||.|||.|| || | . .    . || |.| .|  ... .. .. .
MEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQ

VGTLQYLAPELFENKPYTATVDYWSFG
|||  |..||...||||.  .| ||.|
VGTPYYMSPEVCQNKPYNNKSDIWSLG

Kinase IKKa.AA TyrKc 15-301 22 7.8e-15 17.19 SMART 1-280 (280) Show / Hide
Range on Protein: 15-301
Range on HMM: 1-280/280
Sequence Identity: 22% (70 aa)

WEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLELSSKNRERWCHEIQIMKKL--DHANVVK---ACDVPEELNFLINDVPLLAMEYCSGGDLRKLL--
 .. . || | || | . . .   .. |.|... .     ||  ..|..||.||  .| |.|.   .|  ...  |.  . ... |||...|||.. |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRK

NKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQG-------SLCTS-------FVGTLQYLAPELF
..|.    |. .. ||   .| .| .|||....|||||   |. . . .   . || | | ..|.. .       .  ..       ..  .  .||| .
HRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

ENKPYTATVDYWSFGTMVFECIA-GYRPFLHH----LQPFTWHEKIKKKDPKCIFAC--EEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLML---NWD
  . .|   | |||| . .|    |  |        . ..  .|..|. .   . .   . |                 .  |.  .   |.|.   . |
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS----------------F--VCCPDEMYQIMKQCWHED

PQQRGGPIDLTLKQPRCF
| .|    ..     .||
PEDRPTFSEI----HECF

Kinase IKKa.AA STE 15-75 24 1.7e-09 29.82 In-house 1-94 (359) Show / Hide
Range on Protein: 15-75
Range on HMM: 1-94/359
Sequence Identity: 24% (23 aa)

WEMRERLGTGGFG-NVSLYQHRELDLK--------------IAIKSCRLELSS----------------KNRERWCHEIQIMKKLD--HANVVK
||  |..| |.||  .  . |   ..               .|||  .|| ..                .....  .||.||||..  | |.||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVK

Kinase IKKa.AA Pkinase_Tyr 91-145 35 2.6e-09 32.15 Pfam 82-137 (270) Show / Hide
Range on Protein: 91-145
Range on HMM: 82-137/270
Sequence Identity: 35% (20 aa)

PLLAMEYCSGGDLRKLLNKP-ENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDL
... |||. .|||.. | |. |.   |. ...|.   .| .|  ||.....|||||
IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase IKKa.AA Pkinase_Tyr 15-75 26 6.7e-09 30.76 Pfam 1-68 (270) Show / Hide
Range on Protein: 15-75
Range on HMM: 1-68/270
Sequence Identity: 26% (18 aa)

WEMRERLGTGGFGNVSLYQHR----ELDLKIAIKSCRLELSSKN--RERWCHEIQIMKKL-DHANVVK
 .. . || | ||.| .   .    . ... |.|...   ....  ||   .|..|||.| .| |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVR

Kinase IKKa.AA NEK 15-75 25 3e-08 25.58 In-house 1-68 (286) Show / Hide
Range on Protein: 15-75
Range on HMM: 1-68/286
Sequence Identity: 25% (17 aa)

WEMRERLGTGGFGNVSLYQHRELDLK-----IAIKSCRLE-LSSKNRERWC-HEIQIMKKLDHANVVK
 |  . .| | || | ......   .      ..|   .. .|.|...    .|..| |.|.| |.||
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVK

IKKbetaNEMObind IKKa.AA IKKbetaNEMObind 706-743 44 2.5e-30 73.09 Pfam 1-38 (38) Show / Hide
Range on Protein: 706-743
Range on HMM: 1-38/38
Sequence Identity: 44% (17 aa)

LAQMIEENLNCLGHLSTIIREANEDQSSSLMSLDWSWL
....||||.|....|..........|..||||||||||
SEDLIEENHNYCTQLESMMQDTMKEQDQSLMSLDWSWL