KSR1

Species: Mouse
Alias: KSR1, Ksr
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: RAF
Subfamily: KSR

Sequence

Name Sequence Type Origin Length Description Download
KSR1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
KSR1.AA Protein Sugen 887 None Fasta, JSON
KSR1.NA RNA Sugen 4129 None Fasta, JSON

Protein domain

Protein domains of KSR1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1 KSR1.AA C1 334-377 22 2.8e-10 41.41 SMART 1-61 (61) Show / Hide
Range on Protein: 334-377
Range on HMM: 1-61/61
Sequence Identity: 22% (14 aa)

HRFSTKSWLSQVCNVCQKSMIF---------GVKCKHCRLKCHNKCTKEAP--------AC
|....... .  |..|.|....         |..| .|..|||.|| . .|        .|
HHWHWWRFKPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC

Kinase KSR1.AA KSR 577-841 59 3e-207 694.78 In-house 1-272 (272) Show / Hide
Range on Protein: 577-841
Range on HMM: 1-272/272
Sequence Identity: 59% (163 aa)

VELGEPIGQGRWGRVHRGRWHGEVAIRLLEMD-GHNQDH-LKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKG-RTLHSFVRDPKTSLDINK
...||.|||||.|.||||.|||||||.|..|| .|...| |..||.|||.|..|||||.|||||||||||||||..|.||| .||..........||.|.
LKYGECIGQGRFGKVHRGHWHGEVAIKLYYMDHIHDEHHDLEDFKDEVMMYKNTRHENIVLFMGACMNPPHLAIVMSLCKGSQTLYHHIHVRREKLDMNR

TRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDN-GKVVITDFGLFGISGVVREERRENQLKLSHDWLCYLAPEIVREMIPGRDEDQ---LPFSKAADVY
|.||||.|..||||||||||.||||||||.||.| |||||||||||.|........||..|...|.||||||||..|.| |..||.|   ||||...|||
TMQIAQQICQGMGYLHAKGIIHKDLKSKNIFYENKGKVVITDFGLFSITRLLHCCQREDHLCIPHGWLCYLAPELIRAMRPNYDEYQCMCLPFSHHSDVY

AFGTVWYELQARDWPFKHQPAEALIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMDML
||||.|||.....||||.|.||..|||...|||.|.||..|..|.|. |||..||....||||.|. .|.||
AFGTIWYEMICGEWPFKYQCAESIIWQMCQGEGMRQVLRNVQCGREMKEILMMCWSYEPQERPTFQDIMKML

Kinase KSR1.AA RAF 577-841 51 5e-174 584.43 In-house 1-275 (275) Show / Hide
Range on Protein: 577-841
Range on HMM: 1-275/275
Sequence Identity: 51% (142 aa)

VELGEPIGQGRWGRVHRGRWHGEVAIRLLEMD-GHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNP--PHLAIITSFCKGRTLHSFVRDPKT-SLDIN
|..||.|||||.|.|.||.|||.||...|.|. ......|. ||.|||.|..|||||.|||||.||.|  ||.||.|..|||.||.......|| ..|.|
VQIGERIGQGRFGTVYRGHWHGDVAVKTLNMKYPTPEHQLQAFKNEVMMYKKTRHENIVLFMGYCMKPDNPHYAIVTQWCKGSTLYHHIHVQKTEKFDMN

KTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKV-VITDFGLFGISGVVREERRENQLKLSHDWLCYLAPEIVREMIPGRDEDQ---LPFSKAADV
.|.||||.|..||.|||||.|.|.||||||.|..|||| |||||||| .... ...||..||...|.|.|..|||..|.| |..||.|   .|||...||
WTIQIAQQICQGMDYLHAKNIIHRDLKSKNIFLHNGKVVVITDFGLFTVKRCRWCKRRKQQLCQPHGWICWMAPEVIRMMRPDWDEYQCDCNPFSFQSDV

YAFGTVWYELQARDWPFK-HQPAEALIWQIGSGE-GVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMDML
||||||||||.|..||.. .|..|..||....|. ...|..|.|...||. |.|..||... .|||||. .|.|.
YAFGTVWYELMAGEWPYQHIQWHEQIIWMVCRGYLRMDRSKARVQCPKEMKELLMECWSYQPEERPSFQQIMKMI

Kinase KSR1.AA RAF 577-843 33 3e-75 243.36 In-house 1-282 (282) Show / Hide
Range on Protein: 577-843
Range on HMM: 1-282/282
Sequence Identity: 33% (95 aa)

VELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKL---FKKEVMNYRQTRHENVVLFMGACMNPPH---LAIITSFCKGRTL--HSFVRDPKTS
|.... ||.|. | | ||.|||.||.. | .    .. ..    || ||  |..||| |..|||| .|  |.   .||.| .| . .|  |  | ...  
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMG-YMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREK

LDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNG-KVVITDFGLFGISGVVREE-RRENQLKLSHDWLCYLAPEIVR-EMIPGRDE----DQLP
.|.... .|.. . .|| ||||| |.| ||||.|.| ... .|.|.||||  .    |.  |.. |..    |  ..|||..|  ||  | .    |..|
FDMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVK--TRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENP

FSKAADVYAFGTVWYELQARDWPF--KHQPAEALIWQIGSGEGVRRVLASVS-LGKEVGEILSACWAFDLQERPSFSLLMDMLER
.|   |||.||.| ||| .|  |.    .  .  |. .| |    .  .  .   |   . .. ||.|. .|||.|  .. ... 
YSFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV

Kinase KSR1.AA TKL 583-841 20 3.6e-72 246.07 In-house 1-364 (364) Show / Hide
Range on Protein: 583-841
Range on HMM: 1-364/364
Sequence Identity: 20% (76 aa)

IGQGRWGRVHRGRWHG-----------EVAIRLLEMDG-------------------------HNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPH-
||.|. | |..|.|.|           .||.  . ..                          ...   . ...|.|  ...||.|.|.|||.|..||. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHA--------KGIVHKDLKSKNVFYD-NGK--------------V
            |.|.. .|.| .|....        .... ..|..| .|| |||.        ..|.| ||||||.. | |..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

VITDFGLFGIS----GVVREE----------RRENQLKLSHDWLCYLAPEIVREMIPGR-----DEDQ---LPFSKAADVYAFGTVWYELQARDWPFKHQ
 |.||||        .  . .          ......     .....|||. |.... .     || .   ...|...|||.|| |..|. .| .|....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

PAEALI-------WQIGSGEGVRRVLAS------------VSLGKEVGEILSACWAFDLQERPSFSLLMDML
| .  |       .... ..  .| .               .  ... ...  ||. | ..||||. ... |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase KSR1.AA TKL-Unique 579-841 26 5.5e-35 120.87 In-house 1-290 (290) Show / Hide
Range on Protein: 579-841
Range on HMM: 1-290/290
Sequence Identity: 26% (79 aa)

LGEPIGQGRWGRVHRGRWHGE-VAIRLLEM-DGHNQDHLKLFKKEVMNYRQTR-HENVVLFMGACM----NPPHLAIITSFCKGRTLHSFVR--------
 .. ||.|  |.| .| |.|. |||  ..   . . . .. |..||      . |.|.|..||.||     ||.. |....| | .|..           
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-DPKTSLDINKTRQIAQEIIKGMGYLHAKG--IVHKDLKSKNVFYDNG------KVVITDFGLFGISGVVREERRENQLKLS-H-----DWLC----YLA
  ... |. ..  ..|. | .|| ||| ..  | | ||||.|.  ||.      .. | ||||      ..   ..|. ... |     .  |    ..|
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGL------SKFNSKINKMTNNEHKGTRNQTRCGSFRWMA

PEIVREMIPGRDEDQLPFSKAADVYAFGTVWYELQARDW------PFKHQPAEALIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLM
||. |            .|. .|||.||.| .|.  |.       |...   |...  . . |   |.  . .. ||  ... .||. | ..||||.   
PEVLRMNF-------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEII

DML
  |
HRL

Kinase KSR1.AA Pkinase_Tyr 577-717 27 5.5e-34 115.72 Pfam 1-157 (270) Show / Hide
Range on Protein: 577-717
Range on HMM: 1-157/270
Sequence Identity: 27% (44 aa)

VELGEPIGQGRWGRVHRGRWH-------GEVAIRLLEMDGHNQDH--LKLFKKEVMNYRQT-RHENVVLFMGACM--NPP-HLAIITSFCKGRTLHSFVR
...|. .|.|  |.|..|.|.        .||.  |  .|. ...  .. | .|.   .|  .|.|.| ..|.|.    | .. |.. ....  |... |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DP---KTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYD-NGKVVITDFGL
..   | .|..    |....| ||| ||..|...| ||  .|.  . |..| |.||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL

Kinase KSR1.AA Pkinase 577-717 22 1.9e-29 105.24 Pfam 1-158 (293) Show / Hide
Range on Protein: 577-717
Range on HMM: 1-158/293
Sequence Identity: 22% (36 aa)

VELGEPIGQGRWGRVHRGRWHGE---VAIRLLEMDGHNQDHLKLFKK--EVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGR----TLHSFVR-DPK
 ..|..||.|  |.| .....|.   ||.  .. .. . . ..   .  |.   .  .|.|.| . .......|. ... .| |      |..... . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TSL--DINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYD-NGKV----VITDFGL
...  . .  . .. .|..|. |.|..||.| |||. |...| || .     |.||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL

Kinase KSR1.AA TK 577-778 13 2.8e-29 94.69 In-house 1-387 (486) Show / Hide
Range on Protein: 577-778
Range on HMM: 1-387/486
Sequence Identity: 13% (52 aa)

VELGEPIGQGR---WGRVHRGRWHG----------------------------EVAIRLLEMD-GHNQDHLKL--------------FKKEVMNYRQ--T
..||. .|.|    .|.|..|.|.|                            .||.  |  . ...|.  ..              .  | .  ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHENVVLFMGACMNP------------PHLAIITSFCKGRT----LHSFVR--DPKTSLDINKTRQ----------------------------------
.|.|.| . |.|. .            ... |.. ....      |... |  .||..   ..                                     
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IAQEIIKGMGYLHAK------GIVHKDLKSKNVFYDNGK------------VVITDFG----
                                      ... | .|| |||.|      ..|| ||   |.  ....            . |.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LFGISGVVREERRENQLKLSHDWLC----------------------YLAPEIVREMIPGRDEDQLPFSKAADVYAFGTVWYEL
    |    .   . .| .. . . .                         ..||| ... .. . |    |. . ||..|| . .|.
GSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI

Kinase KSR1.AA S_TKc 577-844 18 6e-29 103.41 SMART 1-231 (231) Show / Hide
Range on Protein: 577-844
Range on HMM: 1-231/231
Sequence Identity: 18% (54 aa)

VELGEPIGQGRWGRVHRGRWHG---EVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKG--RTLHSFVRDPKTS---
 |....||.|  |.|...|...   .|||  .          . ...|.   .. .|.|.| . ... .  || ... .| |   .|... .. ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERRENQLKLSHDWLCYLAPEIVREMIPGRDEDQLPFSK-A
  ..   .| ....|.... |.| .||.| |||  |.. |.  . |.||||  .          . .  .   . |.|||..            ...| .
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGT---PWYMAPEVL------------GYGKCK

ADVYAFGTVWYELQARDWPFKHQPAEALIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMD------MLERL
.|....| . ||. ..  ||     .... .||               .|. .... |. .| ..||.   ..       . . .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase KSR1.AA Dicty4 577-717 34 1.7e-27 88.89 In-house 1-160 (277) Show / Hide
Range on Protein: 577-717
Range on HMM: 1-160/277
Sequence Identity: 34% (55 aa)

VELGEPIGQGRWGRVHRGRWHG-EVAIRLLEMDGHN--QDHLKLFKKEVMNYRQTRHENVVLFMGACM----NPPHLAIITSFC-KGRTLHSFVRD----
   .. ||.|  | |..|.| | |||. .|  .  |  .. |. |.|||    . || |..||||||     .|. . | | .. || .|.|  .|    
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKG-NLYSLLHDKPSE

--PKTSLDINKTRQ---IAQEIIKGMGYLHAKG--IVHKDLKSKNVFYDNGKVV-ITDFGL
  ....||    ..   .|  . .|| .||.    |.| |||| |   |  ..| ..||||
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGL

Kinase KSR1.AA DRK 577-717 35 4.2e-25 81.98 In-house 1-146 (258) Show / Hide
Range on Protein: 577-717
Range on HMM: 1-146/258
Sequence Identity: 35% (52 aa)

VELGEPIGQGRWGRVHRGRWHG-EVAIRLLEMDGHN-QDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKT
.  |  || | .| | || | | .||.  |  .  |  . |. |..|.    | || |...|||.| |||   |.. .     | .   |.. ..|    
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

RQIAQEIIKGMGYLHAKG--IVHKDLKSKNVFYDNG-KVVITDFGL
 |..  . ||| |||     |.| |||| |   |   .| . ||||
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL

Kinase KSR1.AA MLK 577-718 25 1.8e-21 71.36 In-house 1-180 (291) Show / Hide
Range on Protein: 577-718
Range on HMM: 1-180/291
Sequence Identity: 25% (46 aa)

VELGEPIGQGRWGRVHRGRWHG-E-----VAIRLLEMDGHNQDHL-----KLFKKEVMNYRQTRHEN----VVLFMGACMNPPH-LAIITSFCKGRTLHS
 .. | || |  | |..|||.. .     ||..  . .            . |..|..  |  .|.|    .. |.|.| .||. ..|.. .| |  |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

FVRD--PKTS-----------LDINKTRQIAQEIIKGMGYLHAKG---IVHKDLKSKNVFYD-------NGKVVITDFGLF
. ..  .| .            |     ..|  . .|| |||..    |.| ||||.|.  |       .|...|.|||..
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS

Kinase KSR1.AA MLK 577-703 30 6e-20 62.42 In-house 1-134 (280) Show / Hide
Range on Protein: 577-703
Range on HMM: 1-134/280
Sequence Identity: 30% (42 aa)

VELGEPIGQGRWGRVHRGRWHG-EVAIRLLEMDGHNQDHLKL------FKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSL
... | || |. |.|.|. |.| |||..    |. .||  .        ..|   .   .|.|..   |.|...||| ..  .|.|  |   ..  .  .
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQDP-EQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLEDPHLCLVMEYCRGGSLNRVCAGKRIPP

D--INKTRQIAQEIIKGMGYLHAKG---IVHKDLKSKNV
.  .|   |||    .|| |||  .   |.| ||||.|.
HVLVNWAVQIA----RGMNYLHNEAPVPIIHRDLKSSNI

Kinase KSR1.AA TyrKc 577-841 21 1.3e-16 45.94 SMART 1-280 (280) Show / Hide
Range on Protein: 577-841
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

VELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQT--RHENVVLFMGACMNP-------PHLAIITSFCKGRTLHSFVRDPKT
..||. .| |  |.|..|.|  .||.  |  |      .. | .|    ..   .|.|.| . |.|. .       . | |.. ....  |... |... 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

SLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGK-VVITDFGLFGISGVVREERRE-------NQLKLS---HDW----LCYLAPEIVREMI
 |   .  ...  | .|| ||| |...| ||   |. ..... | |.||||       |.   .          . .   .      .  .|||  .. .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL------SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

PGRDEDQLPFSKAADVYAFGTVWYELQAR-DWPFKH-----QPAEALIWQIGSGEGVRRVLA-----SVSLGKEVGEILSACWAFDLQERPSFSLLMDML
         |. . ||..|| . .|.  . . |         ... .| .. .|.  ..        .|   .|. .| . ||..|  .||.|| . . .
---------FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF





Kinase KSR1.AA MLK 761-841 24 2.3e-07 21.72 In-house 212-291 (291) Show / Hide
Range on Protein: 761-841
Range on HMM: 212-291/291
Sequence Identity: 24% (20 aa)

PFSKAADVYAFGTVWYELQARDWPFK-HQPAEALIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMDML
..|...||. .| | .|. .|  |.| |. . | .|...  .  . .  .    .   . .. ||  |  .||||.  .  |
KYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST--CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase KSR1.AA TK 818-841 37 7e-06 14.9 In-house 463-486 (486) Show / Hide
Range on Protein: 818-841
Range on HMM: 463-486/486
Sequence Identity: 37% (9 aa)

EILSACWAFDLQERPSFSLLMDML
...  ||..| ..||.|| | ..|
DLMQQCWHYDPEDRPTFSQLHEQL

Kinase KSR1.AA Pkinase 742-841 15 3.1e-05 19.57 Pfam 177-293 (293) Show / Hide
Range on Protein: 742-841
Range on HMM: 177-293/293
Sequence Identity: 15% (19 aa)

YLAPEIVREMIPGRDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQ------PAEALIWQIGSGEGVRRVLASVSLG-----------------KEVGE
|.|||..|        .. . ....|....| . ||.  .  ||...         ..| .|....  .    . |                   .|  .
YMAPEVIR--------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

ILSACWAFDLQERPSFSLLMDM--L
... |...| ..||..  ..    .
FIKWCLCKDPKKRPTAEQILQHPWF

Kinase KSR1.AA MLK 817-841 32 6.9e-05 11.83 In-house 256-280 (280) Show / Hide
Range on Protein: 817-841
Range on HMM: 256-280/280
Sequence Identity: 32% (8 aa)

GEILSACWAFDLQERPSFSLLMDML
. ..  ||. |  .||.|| ... |
AKLMQDCWNQDPHKRPKFSEILQQL

Kinase KSR1.AA Pkinase_Tyr 814-841 32 0.000132 16.22 Pfam 243-270 (270) Show / Hide
Range on Protein: 814-841
Range on HMM: 243-270/270
Sequence Identity: 32% (9 aa)

KEVGEILSACWAFDLQERPSFSLLMDML
.|. ...  ||..| ..||.|| .  .|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase KSR1.AA MLK 762-786 32 0.012704 4.23 In-house 203-227 (280) Show / Hide
Range on Protein: 762-786
Range on HMM: 203-227/280
Sequence Identity: 32% (8 aa)

FSKAADVYAFGTVWYELQARDWPFK
.||. ||  .| .  ||  .  |..
WSKGSDVWSYGVLLWELLTGEVPYR

Kinase KSR1.AA Pkinase_Tyr 743-778 25 0.031493 8.17 Pfam 181-207 (270) Show / Hide
Range on Protein: 743-778
Range on HMM: 181-207/270
Sequence Identity: 25% (9 aa)

LAPEIVREMIPGRDEDQLPFSKAADVYAFGTVWYEL
.|||  ....         |. . ||..|| ...|.
MAPECINYGK---------FTTKSDVWSFGVLMWEI

Kinase KSR1.AA DRK 820-843 37 0.044358 2.88 In-house 235-258 (258) Show / Hide
Range on Protein: 820-843
Range on HMM: 235-258/258
Sequence Identity: 37% (9 aa)

LSACWAFDLQERPSFSLLMDMLER
.  ||  | | |||.   .  || 
MNDCWNEDPQHRPSMQECLERLEA

Kinase KSR1.AA Dicty4 761-789 41 0.164774 1.0 In-house 193-223 (277) Show / Hide
Range on Protein: 761-789
Range on HMM: 193-223/277
Sequence Identity: 41% (13 aa)

PFSKAADVYAFGTVWYELQARDWPFK--HQP
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PYNEKADVYSFGIVLWEILTRQEPYQKHHMP