LMR1

Species: Mouse
Alias: Aatk, LMR1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Lmr

Sequence

Name Sequence Type Origin Length Description Download
LMR1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 274 Kinase domain by global Sugen HMM Fasta, JSON
LMR1.NA RNA Sugen 5370 None Fasta, JSON
LMR1.AA Protein Sugen 1374 None Fasta, JSON

Protein domain

Protein domains of LMR1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LMR1.AA Lmr 135-408 72 1.8e-229 768.65 In-house 1-283 (283) Show / Hide
Range on Protein: 135-408
Range on HMM: 1-283/283
Sequence Identity: 72% (206 aa)

LLYLKEIGHGWFGKVFLGEVHS---GVSGTQVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTE
|.|..|||.||||||.||||||   |.|..|||||||..|||.|||||||.|.||||.|||.|.||||.||.|..||||||||||.||||.|||.||..|
LNYIQEIGNGWFGKVLLGEVHSLHPGMSKAQVVVKELRASASPQEQMQFLQEVQPYRELQHPNVLQCLGQCVETIPYLLVMEFCPYGDLKNYLRKCRPME

SMAPDP-----LTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQ-LWVPLRWIAPELVDEVHGNLLVVDQT
.|.||.      ||||||||.|||..|.|.|..||||||||||.|.||||||.|||||.||.|.|||..|.|| .|||||||||||.||.|.||||||||
HMMPDKPPRQTMTLQRMACEIACGLAHMHQHHFVHSDLALRNCQLCADLTVKIGDYGLAHCQYKEDYYITKDQCHWVPLRWIAPELMDEFHQNLLVVDQT

KSSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYL
|.||.||||||.|||||..|||||.||| ||||..||||..|||||||||..||||||.|||||.||.||||||.||.||.||
KYSNIWSLGVTMWELFEFAAQPYPHHSDEQVLAQVVREQDIKLPKPQLQLPYSDRWYEIMQFCWMQPDQRPTAEDVHRLLTYL

Kinase LMR1.AA TK 135-405 19 2.5e-84 282.48 In-house 1-486 (486) Show / Hide
Range on Protein: 135-405
Range on HMM: 1-486/486
Sequence Identity: 19% (94 aa)

LLYLKEIGHGWFG---KVFLGEVHSGV-----------------------SGTQVVVKELKV--SASVQEQMQ--------------FLEEAQPYR--AL
. ..|..|.|.||   .|..||....                          |.| || ||   ..| .|...              ..||..  .  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHSNLLQCLAQCAEV------------TPYLLVMEFCPLGD----LKGYLRSCRVTESM-----------------------------------------
.| |...... | ..             |...|||..|.||    |. |||.|| ...                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------APDPLTLQRMACEVACGVLHLHRH------NYVHSDLALRNCLLTADLT-----------VKVGDYG---
                               ... .|  |.. .|||  .||..      |.|| ||| ||||.. ...           .|..|.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSHCKYREDYLVTAD------------------------QLWVPLRWIAPELVDEVHGNLL--VVDQTKSSNVWSLGVTIWELFELG-AQPYPQH
     |.   |..|. ....                        . ..|.|| ||| ... .          |  | |||.||..||.| .| ...|...
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SD---------GQVLAYAVREQQL----------KLPKPQLQLALS-------------DRWYEVMQFCWLQ-PEQRPTAEEVHLLL
|.          .|. | .|...|          ....|| ... .             . .|..|| ||   ||.||| ...|  |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase LMR1.AA UTK 135-405 29 6.8e-64 217.46 In-house 1-296 (296) Show / Hide
Range on Protein: 135-405
Range on HMM: 1-296/296
Sequence Identity: 29% (89 aa)

LLYLKEIGHGWFGKVFLGEVHSGV---SGTQVVVKELKVSASVQEQM----QFLEEAQ---PYRALQ-HSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGY
.  ....|.| || |.....          .| ||.....|. | ..    .|.|||.    . ... | |.|. .. |    | ..|.|... |||  |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSCRVTESMAPDPLTLQR---MACEVACGVLHLHRHNYVHSDLALRNCLLTAD-------LTVKVGDYG---LSHCKYR--------EDYLVTAD-QLW
||..| |   .|. ||| .   ||  .|.|. .||....|| ||| ||||....       ...|..|.|   .|.  ..        |.|...|. |  
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

VPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYAVREQQ-LKLPKPQLQLALSDRWYEVMQFCWLQ-PEQRPTAE
.|.|| ||| ...        . | .| |||.||. ||..  |..||| .|. ||.. .|...  . .|.|.   . ... |..|. || . |. ||..|
WPIRWMAPEALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWH-QVCNGGRYRMPCPW---DCPHPVYRLMHRCWHYDPQERPDFE

EVHLLL
..   .
DLVQQM

Kinase LMR1.AA TyrKc 135-405 31 4.8e-63 216.67 SMART 1-280 (280) Show / Hide
Range on Protein: 135-405
Range on HMM: 1-280/280
Sequence Identity: 31% (96 aa)

LLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQPYRAL--QHSNLLQCLAQCAEV-------TPYLLVMEFCPLGDLKGYLR
.  .|..|.| ||.|..|.       .|| || || .|    .. |..||.  . |  .| |...... | .         |...|||..|.|||| |||
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYRE-------DYLVTAD--QLW--VPLRWIAPELVDE
..| .      . .|  ..  .|||  .||..|..| ||| ||||.....|||..| |||   | .       || ...   .    .|.|| |||    
KHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

VHGNLLVVDQ--TKSSNVWSLGVTIWELFELGAQPYPQ-----HSDGQVLAYAVREQQLKLPKPQLQLA-----LSDRWYEVMQFCWLQ-PEQRPTAEEV
        .   |  | ||| ||..||.| .|.||||       |. .|..|  .   .. |.  .         .|  |..|. ||   ||.||| .|.
-------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

HLLL
| ..
HECF

Kinase LMR1.AA TK-Unique 135-405 30 1.5e-53 183.04 In-house 1-294 (294) Show / Hide
Range on Protein: 135-405
Range on HMM: 1-294/294
Sequence Identity: 30% (94 aa)

LLYLKEIGHGWFGKVFLGEVHS--GVSGTQ--VVVKELKVSASVQEQMQFLEEAQPYRALQ-HSNLLQCLAQCAEVT-PYLLVMEFCPLGDLKGYLRSCR
|  ...|| | || |. ||| .  .... |  |.|| || .|. .....|| |.| ...|  | |..||| .| . . | ...||.|| |.| .|||.||
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

------------------VTESMAPDPLTLQRMA---CEVACGVLHLHR--HNYVHSDLALRNCLLTADLTVKVGDYGLS-HCKYREDYLVTADQLWVPL
                  ..... ..|.......   ...|||  .|..  .. || ||. ||.||| |...|..|.|.. .   ...|  .  |  .|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWIAPELVDEVHGNLLVVDQTK---SSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYAVREQQLKLPKPQLQLAL-SDRWYEVMQFCW-LQPEQRPTAE
|| |||   .        ...     |.|||.||..||.| |||.|||. .. . .  ..| .   .|.|.      |.. |..|. || . ||.||. .
RWMAPESLKCY-------HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD-IMECIR-DGYRMPQPEH---CCSHEMYNLMKSCWQWEPEERPSFR

EVHLLL
..   |
QIKHRL

Kinase LMR1.AA Pkinase_Tyr 135-310 32 4.7e-52 176.91 Pfam 1-184 (270) Show / Hide
Range on Protein: 135-310
Range on HMM: 1-184/270
Sequence Identity: 32% (60 aa)

LLYLKEIGHGWFGKVFLGEVH--SGVSGTQVVVKELKVSASVQE--QMQFLEEAQPYRAL-QHSNLLQCLAQCA-EVTP--YLLVMEFCPLGDLKGYLRS
.  .|..|.| ||.|..|. .   .  ...| || || .|. ..  .  |..||.  . | .| |...... |  .  |  ...|||..|.|||. |||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

CRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYL-VTADQLWVPLRWIAPE
 | ..  .... .|  |. ..|.|  .|...|..| ||| ||||.| ...||..| ||.   | .||  ....   .| .| |||
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPE

Kinase LMR1.AA InsR 135-407 32 2.2e-47 157.19 In-house 1-278 (278) Show / Hide
Range on Protein: 135-407
Range on HMM: 1-278/278
Sequence Identity: 32% (96 aa)

LLYLKEIGHGWFGKVFLG---EVHSGVSGT--QVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRV
.  ..| | | ||.| .|    . ..   .  .. .| .. .||. |   || ||    .  . .    |  |  . | . |||.  .|||| |||| | 
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

TES----MAP---DPLTLQR---MACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPE-LVDEVHGN
 |       .   .. .|..   || |.. |   |   ..|| ||| |||.  .|.|||.|| |.    |  ||         | || ||| | | |   
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVF--

LLVVDQTKSSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYA-VREQQLKLPKPQLQLALSDRWYEVMQFCW-LQPEQRPTAEEVHLLLSY
      | .| |||.|| .||   ||.|||   |  ||| |       |. |        ...|.|.|. ||  ||  |||. ..  .|  
------TTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPE-----NCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD

Kinase LMR1.AA RTKB 139-405 32 3.9e-44 146.7 In-house 5-264 (264) Show / Hide
Range on Protein: 139-405
Range on HMM: 5-264/264
Sequence Identity: 32% (90 aa)

KEIGHGWFGKVFLGEVHSGVSG-TQVV-VKELKVSASVQEQMQFLEEAQPYRAL-QHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTESMAP
.. |.| || ||.. |   ... .| . .| ||..||  |. .|..|     .| .| |..  .  |   .||.|  |.| || |  ||| || ... . 
EKLGNGAFGEVFQAWVRNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRASQHNPQ

--DPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQTKSSNVWSL
      |   .. .|||  .||.|| .|.||. || |.. .|. |. |.|..     |.|  |.. |  | .| |||.  .   .      |||  |||.
SLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRL--PIKWMAPESWAHRIYT------TKSGDVWSF

GVTIWELFELGAQPYPQHSDGQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCW-LQPEQRPTAEEVHLLL
||| || | ||. ||.|.. |... .   |    ||||..    .   ...|| || . ...||. .|.  ..
GVTMWEIFSLGGTPYQQYRNGDIFYWL--ESGHRLPKPRQ---MPQAADHIMQMCWQMEAQHRPDFDELVDAF

Kinase LMR1.AA Trk 135-405 32 3.7e-42 140.65 In-house 1-275 (275) Show / Hide
Range on Protein: 135-405
Range on HMM: 1-275/275
Sequence Identity: 32% (94 aa)

LLYLKEIGHGWFGKVFLGEVHSGVSGTQ----VVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRS----
.   .|.| | ||||||.| .   ...|    | || ||  ||..    |  ||.    ||| .  .    | .  | |.| |.   |||. |||.    
IVLKWELGEGAFGKVFLAECYN-LCPEQDKMMVAVKTLK-DASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPD

--CRVTESM--APDPLTLQRM---ACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYR-EDYLVTADQLWVPLRWIAPELVDEVHGN
  | .      || |||.. |   | ..| |   .    .|| |.| ||||  ..| ||.||.|.|   |   ||     .   | ||. || .      
AMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESI------

LLVVDQTKSSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYAVREQQ-LKLPKPQLQLALSDRWYEVMQFCW-LQPEQRPTAEEVHLLL
 .    |  | |||.||..|| |. | ||. | |   |  .    .. |. |.     .     |..|  ||  .|.|| .. ..| ..
-MYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPR-----RCPQEVYDIMLGCWQREPQQRMNIKDIHDII

Kinase LMR1.AA Musk 135-348 34 3.1e-39 127.14 In-house 1-229 (282) Show / Hide
Range on Protein: 135-348
Range on HMM: 1-229/282
Sequence Identity: 34% (81 aa)

LLYLKEIGHGWFGKVFLGEVHSGVSG---TQVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSC----
  | ..|| | || ||       | .   | | || ||  || | || |  ||.      | |  . |  |.   |  | .|.   |||  .|.||    
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR

---RVTESMA-------PDPLTLQ-----RMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELV
   | ... .       | |. |.      || ..||| . |    .|| ||| ||||      ||. |.|||.  | .|| .  .   .| ||..||  
TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPE--

DEVHGNLLVVDQTKSSNVWSLGVTIWELFELGAQPY
      ..    |  | ||. ||  ||.|  . |||
-----SIWYNQFTYESDVWAYGVCLWEIFSYALQPY

Kinase LMR1.AA TKL 141-405 19 7.7e-39 135.36 In-house 1-364 (364) Show / Hide
Range on Protein: 141-405
Range on HMM: 1-364/364
Sequence Identity: 19% (74 aa)

IGHGWFGKVFLGEVH-------SGVSGTQVVVKELKVSASVQEQM-------------------------QFLEEAQPY-RALQHSNLLQCLAQCAEVTP
|| | ||.|. |. .       |  .|. |.|| .|.  .  . .                         .|.||     . |.| |..|... | . ..
IGSGGFGEVYKGKWRGWGGKCPS-DTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------YLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRMACEVACGVLHLHRHN--------YVHSDLALRNCLLTADLT----------
             . .|||.|| |.|  ||            .  . |.| ..|.|. .|| .|         .| ||  .|.|.  ..|          
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----VKVGDYGLSHCKYREDYLVT----------------ADQLWV-PLRWIAPELVDEV----------HGNLLVVDQTKSSNVWSLGVTIWELFE--L
    .|..|.||| .. ..                     .    .  .|| |||. ..              .   . .... |.| |. .||..   .
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCR

GAQPYP-QHSDGQVLA-------YAVREQQLKLPKP---------QLQLALSDRWYEVMQFCWLQ-PEQRPTAEEVHLLL
   ||  .... ....       . | . .|..| |         .      ... . || || . ||.||...|.   |
---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LMR1.AA Axl 135-403 30 2.4e-36 126.16 In-house 1-267 (267) Show / Hide
Range on Protein: 135-403
Range on HMM: 1-267/267
Sequence Identity: 30% (86 aa)

LLYLKEIGHGWFGKVFLGEVHSGV-SGTQVVVKELKVSASVQEQM-QFLEEAQPYRALQHSNLLQCLAQCAEVTP------YLLVMEFCPLGDLKGYLRS
.   | .|.| || |  |...    |  .| || .|.  . | .. .|| ||   .  .| | .. .  | ..         . .. |   |||  .|  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTFLLY

CRVTESMAPDPL-TLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPE-LVDEVHGNLLVVDQ
 |. .     || .| .   ..|||.  |  .|..| ||| |||.|  |.|| | |.|||.  |  ||        .| .||| | | |.|         
SRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIAKMPVKWIAIESLADRVY--------

TKSSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCW-LQPEQRPTAEEVHL
|  | ||. |||.||.   |  |||      .  | .. . || |.  .     |  |..|  || ..|..||.  .. .
TSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCM-----DELYDLMYQCWEADPKDRPSFSVLRE

Kinase LMR1.AA S_TKc 135-408 20 2.3e-31 111.45 SMART 1-231 (231) Show / Hide
Range on Protein: 135-408
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

LLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPL--GDLKGYLRSCR----
   |..||.| ||||...  ..  .| .| .|..|         ... | |  .  .| |. ...  . . . . .|||.|.   |||. |.....    
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQT
    .| .|      ........|.. ..|.|. .| ||   | ||.   ..|..| ||.            . . . . ..|||..            .
RFPFPE-HA------RFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----------GYG

K-SSNVWSLGVTIWELFELGAQPYPQHSDGQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCWL-QPEQRPTAEEVHL------LLSYL
| .. .||.|....|..  |  |.|   . |..   ..               |.   . .. |.   ||.|||| |.        .  ..
KCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LMR1.AA Pkinase 135-401 18 2e-20 73.3 Pfam 1-287 (293) Show / Hide
Range on Protein: 135-401
Range on HMM: 1-287/293
Sequence Identity: 18% (55 aa)

LLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKVSASVQEQ-MQFLE--EAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLG----DLKGYLR--
.  .. || | ||.|...  ..     .|.||..|..    .. .. .   |.|  . |.| | ....  . . . . .|||.|. |    ||. |..  
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

-SCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTV----KVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLL
 .....  .  .. ...... ....|. ..|... .| || . |.|.  . ..    |..| ||. ... .   . .. . . ....|||.       ..
RHGCFY--F--SEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV-------IR

-VVDQTKSSNVWSLGVTIWELFELGAQPYPQHS------DGQVLAYAVREQQLKLPKPQLQL----------------ALSDRWYEVMQFCW-LQPEQRP
   . .... .||.|....|..  |  |.| ..      | ... . ... .|. . |..                  ..|.   ...  |. . |..||
GGQYYGPKVDMWSCGCILYEMLC-GRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

TAEEV
|||..
TAEQI

Kinase LMR1.AA Pkinase_Tyr 330-405 38 1.8e-15 53.03 Pfam 197-270 (270) Show / Hide
Range on Protein: 330-405
Range on HMM: 197-270/270
Sequence Identity: 38% (31 aa)

VWSLGVTIWELFELGAQP-YPQHSDGQVLAYA-VREQQLKLPK--PQLQLALSDRWYEVMQFCW-LQPEQRPTAEEVHLLL
||| ||..||.| .|.|| ||  |. .|..|   . .... |.  |       |  |..|. ||  .||.||| .|.|  |
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCP-------DEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase LMR1.AA Musk 382-405 32 0.13416 0.79 In-house 258-282 (282) Show / Hide
Range on Protein: 382-405
Range on HMM: 258-282/282
Sequence Identity: 32% (8 aa)

YEVMQFCW-LQPEQRPTAEEVHLLL
|..|  ||  .|  ||   ..|  .
YQLMRRCWQKNPADRPFFCQIHHCI