Gene MAPKAPK2 (Mouse)

MAPKAPK2

Species: Mouse
Alias: MAPKAPK2, Mapkapk2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: MAPKAPK
Subfamily: MK2

Sequence

Name Sequence Type Origin Length Description Download
MAPKAPK2.NA RNA Sugen 2586 None Fasta, JSON
MAPKAPK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 262 Kinase domain by global Sugen HMM Fasta, JSON
MAPKAPK2.AA Protein Sugen 386 None Fasta, JSON

Protein domain

Protein domains of MAPKAPK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MAPKAPK2.AA MAPKAPK 50-311 74 5.1e-211 707.33 In-house 1-268 (268) Show / Hide 
Range on Protein: 50-311
Range on HMM: 1-268/268
Sequence Identity: 74% (200 aa)

KVTSQVLGLGINGKVLRIFDKRTQQKFALKMLQDCPKARREVELHWRASQCPHIVHIVDVYENLYAG------RKCLLIVMECLDGGELFSRIQDRGDQA
....||||.||||||.....||||||||||.|.|.|||||||||||..|..||||.|.||||| |..      ||||||||||..|||||.|||.||||.
QIWKQVLGIGINGKVMQCYHKRTQQKFALKVLRDSPKARREVELHWMCSGHPHIVQIIDVYENMYQFPHEPSPRKCLLIVMECMEGGELFHRIQERGDQH

FTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILL
||||||..|||.|..|.|..||.||||||.|||||||....||..|||||||||||||.||.|.||||||||||||||||||||||||||||||||||.|
FTEREAAQIMKQICQAVQHCHSMNIAHRDLKPENLLYKDTQPNCVLKLTDFGFAKETTRHNTLMTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYIML

CGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI
|||||||||||.|||||||.||..||||||.||||.|||..|.|||.||.|.||.|.||.||||||||
CGYPPFYSNHGQAISPGMKHRIMNGQYEFPHPEWSCVSEDAKDLIRKLLRTDPTERLTIEEFMNHPWI
Kinase MAPKAPK2.AA MAPKAPK 50-311 56 9.20000000001e-206 643.63 In-house 1-292 (292) Show / Hide 
Range on Protein: 50-311
Range on HMM: 1-292/292
Sequence Identity: 56% (165 aa)

KVTSQVLGLGINGKVLRIFDKRTQQKFALKMLQDC-----PKARREVELHWRASQCPHIVHIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAF
|....|||.||.|||.....|||.|..|.|.|.|.     .||||||||||.....|.||.|.|..|| |...||...||||..|||||..||.||...|
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHF

TEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKE-------TTS--HNSLTTPCYTPYYVAPEVLGPEK----YDKSCD
||||||.||| |..|...|||.||||||.||||.|.|....|...||.|||||||       ||.  ...|.||||||||.||||.|..|    ||||||
TEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCD

MWSLGVIMYILLCGYPPFYSNHG-LAISPG-----------MKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI
||||||||||.||||||||||.|  ..|..           |..||..||||||..|||..|||.|.|||.||...||||.||...||||||
MWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase MAPKAPK2.AA CAMK 55-311 26 3.6e-116 376.0 In-house 1-425 (425) Show / Hide 
Range on Protein: 55-311
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)

VLGLGINGKVLRIFDKRTQ------------QKFALKM---------------------------------LQDCPKARREVELHWRAS------QCPHI
.|| |  ||| . ..|.|.            ||.| |.                                  .|. . |||.|.... .      . |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHIVDVYEN---------------LYAG-RKCLLIVM---ECLDGGEL----FSRIQDRGD-------------QAFTEREASEIMKSIGEAIQYLHSIN
... .|||.                .   .|.. .||   |  .||||    |..|...|.               ||||||. ... | .|..|.|| |
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDVKPENLLYTSKRPN--------------AILKLTDFGFAKETTSHN------------------------SLTTPCYTPYYVA-PEVLGP-----
|.||| ||||.|.... ..              . .|..|||||.. .. .                         ..|.| ||.|.| ||||       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------EKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAIS---------PGMKTRIRMGQYEFPNPE------------WSEVSEE--------VK
         . |...|||||.|||.||.||||||||. ..  |          . .. .|. |.|.|| |.            |...|.|        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

MLIRNLLKTEPTQRMTITEFMNHPWI
 |||..|...|..||||.. .||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MAPKAPK2.AA CAMK1 49-311 37 3.6e-107 312.59 In-house 1-276 (276) Show / Hide 
Range on Protein: 49-311
Range on HMM: 1-276/276
Sequence Identity: 37% (107 aa)

YKVTSQVLGLGINGKVLRIFDKRT---QQKFALKMLQ--DCPKA---------RREVELHWRAS--QCPHIVHIVDVYENLYAGRKCLLIVMECLDGGEL
|.... ..| |  ..| .  .|.|   ....|.|..   .  |          ..|.| . . |  ..|.|. . ..||      . . .||| . ||||
YEFGK-EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYES----DNHFYLVMELVTGGEL

FSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILK--LTDFGFAKETTSHN-SLTTPCYTPYYVAPEVLGP---EKY
| || ..|   .||..|..||| | .|..|.|| .|.||| ||||||| .| .....|  . ||| .| . . .  ..|.| ||.|||||||     . |
FDRIVEKG--NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY

DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEE-VKMLIRNLLKTEPTQRMTITEFMNHPWI
||.||||| ||| |||||||||||.. . .    .   |  ..||||.|.| ..|.. .| .|...|. .|..| |.... |||||
DKACDMWSIGVITYILLCGYPPFYDENVDNE---LFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase MAPKAPK2.AA S_TKc 50-311 33 7.4e-96 325.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-311
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

KVTSQVLGLGINGKVLRIFDKRTQQKFALKMLQDCPKARREVELHWRASQCPHIVHIVDVYENLYAGRKCLLIVMECLDG--GELFSRIQDRGD----QA
    ...| |  ||| .  .|.|....|.|..    ..|||.... .  ..|.||.. ||...     ..| .|||..||  |.||..|..||     . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDK-SCDMWSLGVIMYIL
|.| .|  .|. | .|..|.|| .| |||.||||.| ..      .|..|||.|..       || | ||.|.|||||   .|.| .||.||.|.|.|..
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMN-------HPWI
|||||||. .. . .   .                   |.|.| .||..|. .|..|.|. | ..       |||.
LCGYPPFP-QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MAPKAPK2.AA CDPK 122-311 44 6.3e-85 260.43 In-house 78-271 (271) Show / Hide 
Range on Protein: 122-311
Range on HMM: 78-271/271
Sequence Identity: 44% (89 aa)

IVME--CLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNA----ILKLTDFGFAKETTSH-----NSLTTPC
||||   . ||||| .|...|   |||.||..||. |  |..| || || |||.||||.|..|| ...    ..|. |.| .|.  .      . ... |
IVMETEYCTGGELFDYIIEKGH--FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRC

YTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPW
 ||||.|||||    |...|| ||.|||.|||||||||||      |   |.  .. |.|.|  |||...|.| | |||..| ..| .||.  . ..|||
GTPYYIAPEVLQKK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEI---ME-KVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPW

I
.
F
Kinase MAPKAPK2.AA RAD53 101-311 33 3.2e-79 235.53 In-house 64-305 (305) Show / Hide 
Range on Protein: 101-311
Range on HMM: 64-305/305
Sequence Identity: 33% (84 aa)

PHIVHIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQ--AFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNA-----------
| |. | |....     | . .|.|  .|||||..| ...     |.| .. .. . . .|..|||. .|.||| |||| |. ... .            
PCIIRIYDIFDTP---QKYYYMVLELMTGGELFNKIVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDED

----ILKLTDFGFAKETTSHNS--LTTPCYTPYYVAPEVLGPE---------------KYDKSCDMWSLGVIMYILLCGYPPFYSNHGLA--ISPGMKTR
    ..|.|||| .|  .....  ..| | || ||||||.  .                | |..|.||.|.| ||.||||||| | .  .    . ..  
EISFLIKITDFGLSK--FVGEGSFMKTMCGTPQYVAPEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPF-SDDYTQEMHCMQLFEQ

IRM-GQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI
|.  | |.|| |.|...|||.| ||...|. .|. | || | .||||.
IKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM
Kinase MAPKAPK2.AA Pkinase 50-311 29 6.5e-78 269.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-311
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

KVTSQVLGLGINGKVLRIFDKRTQQKFALKMLQDCPKAR---------REVELHWRASQCPHIVHIVDVYENLYAGRKCLLIVMECLDGG----ELFSRI
 .. ...| |  |.| .  .| |....|.| .  . .           .|.... |  ..|.|| . |..|.    .. . .|||...||    .||..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYI

QDRGDQAF--TEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYT-SKRPNAILKLTDFGFAKE--TTSHNSLTTPCYTPYYVAPEVLG-PEKYDKSC
. . . .|  .|.|.  .|. | ....|.|| .| |||.||||.|.     ..|..|..|||.||   . .   .||.| ||.|.||||.   ..|....
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DMWSLGVIMYILLCGYPPFYSNH----GLAISPGMKTRIRMGQYEFPNPEWSEVS-----------------EEVKMLIRNLLKTEPTQRMTITEFMNHP
||||.|.|.|..|||.|||. .|    . .    |  ||......|. |.|...|                 || | .|...|.  |..| |... ..||
DMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WI
|.
WF
Kinase MAPKAPK2.AA CAMK-Unique 52-311 25 2.1e-70 231.59 In-house 3-363 (363) Show / Hide 
Range on Protein: 52-311
Range on HMM: 3-363/363
Sequence Identity: 25% (92 aa)

TSQVLGLGINGKVLRIFDKRTQQKFALKMLQD--------CP-----------------KARREVELHWRASQCPHIVHIVDVYENLYAGRK--------
. ...| |  |.|.. .|. |  |.| ||..          .                 |..||... |.    |.|....|.   ..  ||        
MHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQI-WKMVDHPNIIKLYDWNNPIFCDRKYPLCDLII

-------CLLIVMECLDGGELFSRIQD------------------RGDQAFTE--REASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRP------
        . |||| ..||.||. ||.                  |  . |.|  .... || .. .|. |.||..| ||| |.||... .  .      
KTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHR

-------NAILKLTDFGFAKETTSHNSLT---TPCYTPYYVAP--------------EVLGPEKYDKSC----DMWSLGVIMYILLCGYPPFYSNHGL--
       |  .||.||| ...  .  . .   | | ||.|.||              ||..  .||  |    | ||||||||..|||.|||...     
DFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRD

--AISPGMKTRIRMGQY-EFPNPEWSE---VSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI
   .  .   .|. |.| .|... |.    .|.| | .. ......| .| .. |   |.||
YENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase MAPKAPK2.AA RSK 53-311 35 4.7e-70 239.06 In-house 1-278 (278) Show / Hide 
Range on Protein: 53-311
Range on HMM: 1-278/278
Sequence Identity: 35% (102 aa)

SQVLGLGINGKVL---RIFDKRTQQKFALKMLQD---CPKAR------REVELHWRASQCPHIVHIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRG
 .||| | .|||    .. .. |.| .| | |.    .....      .|..   |  |.| ||.  ....      . | ..||.. ||||| ..| ..
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQT----EGKLYLIMEYCRGGELFTHLQKEK

D-QAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPN-AILKLTDFGFAKE-TTSHNS-LTTPCYTPYYVAPEVLG---PEK-YDKSCDM
    |.|.||...|  |  |...||.  | ||| |||| ||.... | . .|||||||.|.   .||. . |.|||  |.|||.|    ... .||.|| 
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDW

WSLGVIMYILLCGYPPFYS---NHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMT-----ITEFMNHPWI
|||||.|| .| |.|||..   |.   |.    .||. |.. .. |.|...|.| | ||| .|. .| .| .     . |  .|||.
WSLGVLMYEMLTGCPPFQGPNDNNRKEIM----KRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase MAPKAPK2.AA Ciliate-E2 69-311 26 2.7e-66 226.54 In-house 43-365 (365) Show / Hide 
Range on Protein: 69-311
Range on HMM: 43-365/365
Sequence Identity: 26% (90 aa)

DKRTQQKFALKMLQDCPKARREVELHWR-----------------ASQCPHIVHIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDR----------GD
.| .....|.|...   .   . |.|                     ..|.|. .......    .... .||| ..||.||..|...          . 
EKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQE--KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-

QAFTEREASEIMKSIGE---------------AIQYLHSIN-IAHRDVKPENLLYTSKRPNAILKLTDFGFAK------------------------ETT
. |||.|...||| | .               |..|||| | | ||| ||||.|.        .|..|||..|                        ..|
KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRT

SH--------NSLTTPCYTPYYVAPEVLGPEK---------YDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPE--------
.         |   | |.||.|.|||.|. .|         ||..||.||||||.|..|.|.|||               |  ....||.||        
PGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCI

------WSEVSEEVKMLIRN----LLKTEPTQRMT-ITEFMNHPWI
      | ..|.|.| ||..    .|. .| .|.| . . .||||.
QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MAPKAPK2.AA RSK 49-311 32 2.3e-63 216.84 In-house 1-271 (271) Show / Hide 
Range on Protein: 49-311
Range on HMM: 1-271/271
Sequence Identity: 32% (90 aa)

YKVTSQVLGLGING---KVLRIFDKRTQQKFALKMLQ-DCPKAR-----REVELHWRASQCPHIVHIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDR
| .  ...| |  .    . ..  | |.|..| | .. .  ...      |..   | .. | ||   .|..      . . ..|. . ||.|| |..  
YELH-ECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQD----EGKVYMIMDFMRGGDLFDRLLKQ

GDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSK--RPNAILKLTDFGFAKETTSHNS-LTTPCYTPYYVAPEVLGPEKYDKSCDMWSLG
    |.|||....|  |  | .||||  |.||| |||| || ..   |  | |..||||||.  ..|  | |.|||  |.|||||    .|..|| ||.|
--KMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHI-KICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFG

VIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTI-----TEFMNHPWI
|.||. | |..||....        . ||  |.. .  . |. .|.| | |.| .|.  |..| .       .  .|||.
VLMYEMLTGCTPFQNKPRDTPMNIIQ-RIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase MAPKAPK2.AA TyrKc 50-311 20 1.1e-09 -66.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-311
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

KVTSQVLGLGINGKVLRIFDKRTQQKFALKMLQDCPKARREVE---LHWRAS--QCPHIVHIVDVYEN-----LYAGRKCLLIVMECLDGGELFSRIQDR
 .  ..|| |  |.| .   |   .. | |||...   |..        .    . |.|| .. |        .|..   |.||||  ..| | ......
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP--LMIVMEYMPHGDLKDYLRKH

GDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSH-------NSLTT----PCY--TPY-YVAPEVLGPEK
... .. ..  ...  | .  .|||| |. |||    | |.....   . | .||| ... ...          ..     .    |.   |||..   |
RPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDKSCDMWSLGVIMY-ILLCGYPPFYS-----NHGLAISPGMKTRIRMGQYEFPNPEWSE-----VSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI
.    | || || |. |.  | .| .           .    |.. || | . .     .      ..|. ....   . .| .| | .|   |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MAPKAPK2.AA RAD53 51-79 41 0.010502 3.3 In-house 2-30 (305) Show / Hide 
Range on Protein: 51-79
Range on HMM: 2-30/305
Sequence Identity: 41% (12 aa)

VTSQVLGLGINGKVLRIFDKRTQQKFALK
..| .|| |  |.|.. ..|.| ||.| |
YMSKELGSGNFGTVKLAYEKKTCQKVAIK