MAPKAPK3

Species: Mouse
Alias: AI874665, MAPKAPK3
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: MAPKAPK
Subfamily: MK2

Sequence

Name Sequence Type Origin Length Description Download
MAPKAPK3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON
MAPKAPK3.NA RNA Sugen 2816 None Fasta, JSON
MAPKAPK3.AA Protein Sugen 384 None Fasta, JSON

Protein domain

Protein domains of MAPKAPK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MAPKAPK3.AA MAPKAPK 46-306 74 1.4e-209 702.56 In-house 1-268 (268) Show / Hide
Range on Protein: 46-306
Range on HMM: 1-268/268
Sequence Identity: 74% (199 aa)

QLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHG------KRCLLIVMECMEGGELFSRIQERGDQA
|..|||||.|.||||..|||.|..||.|||.|.||||||.||..||..||.||||.|.||||||...      ..|||||||||||||||.||||||||.
QIWKQVLGIGINGKVMQCYHKRTQQKFALKVLRDSPKARREVELHWMCSGHPHIVQIIDVYENMYQFPHEPSPRKCLLIVMECMEGGELFHRIQERGDQH

FTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILL
|||||||.||..|..|.|..||.||||||.|||||||.......|||||||||||||| .|.|.||||||||||||||||||||||||||||||||||.|
FTEREAAQIMKQICQAVQHCHSMNIAHRDLKPENLLYKDTQPNCVLKLTDFGFAKETTRHNTLMTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYIML

CGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWI
||.||||||.|||||||||.||. |||.||.||| .||||||.||| ||.|||||||||..|||||||
CGYPPFYSNHGQAISPGMKHRIMNGQYEFPHPEWSCVSEDAKDLIRKLLRTDPTERLTIEEFMNHPWI

Kinase MAPKAPK3.AA MAPKAPK 46-306 55 4.3e-206 644.66 In-house 1-292 (292) Show / Hide
Range on Protein: 46-306
Range on HMM: 1-292/292
Sequence Identity: 55% (163 aa)

QLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDS-----PKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAF
.|.|.|||.|..|||..|.|.|.||..|.|.|.|.     .|||.||..||...| |.||.|.|..|||.....|...|||||||||||..||.||...|
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHF

TEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKE-------TT---QNALQTPCYTPYYVAPEVLGPEK----YDKSCD
|||||..||.||..|..||||.||||||.||||.|.|........||.|||||||       ||   ...|.||||||||.||||.|..|    ||||||
TEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCD

MWSLGVIMYILLCGFPPFYSNTG-QAISPG-----------MKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWI
||||||||||.|||.||||||.| ...|..           |..||. |||.||..|| ..||.||.||| ||..|||.||||.|.||||||
MWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI

Kinase MAPKAPK3.AA CAMK 51-306 26 1.1e-117 380.93 In-house 1-425 (425) Show / Hide
Range on Protein: 51-306
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)

VLGLGVNGKVLECYHRRSG------------QKCALKL---------------------------------LYDSPKARQEVDHHWQASG------GPHI
.|| |  ||| .|.|....            ||.| |                                   .|  . |.|.. ... .|       |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRILDVYENMHHG---------------KRCLLIVM---ECMEGGEL----FSRIQERGD-------------QAFTEREAAEIMRDIGTAIQFLHSRNI
.....|||..|..               .... .||   | ..||||    |..|.|.|.               ||||||. ..| |  |....||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDVKPENLLYTSKEKD--------------AVLKLTDFGFAKETTQNA-------------------------LQTPCYTPYYVA-PEVLGP------
.||| ||||.|......|              . .|..|||||.. ...                          ..|.| ||.|.| ||||        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAIS---------PGMKRRIRLGQYSFPNPE------------WLDVSED--------AKQ
        . |...|||||.|||.||.|||.||||. ... |          . ....|. |.|.|| |.            | |.|..        .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIRLLLKTDPTERLTIMQFMNHPWI
||| .|..||..|.|| | .||||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase MAPKAPK3.AA CAMK1 97-306 44 4e-110 321.32 In-house 68-276 (276) Show / Hide
Range on Protein: 97-306
Range on HMM: 68-276/276
Sequence Identity: 44% (97 aa)

PHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLK--LTDFGFAK
|.|. . ..||   |    . .||| . ||||| || |.|   .||..|..||. |  |....||..|.||| ||||||| .|. |. .|  . ||| .|
PNIIKFYEWYESDNH----FYLVMELVTGGELFDRIVEKG--NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSK

ETTQN--ALQTPCYTPYYVAPEVLGP---EKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSED-AKQLIRLLLK
 . ..   ..|.| ||.|||||||     . |||.||||| ||| ||||||.||||......    . . |  ..| ||.|.| ..|.  ||..|. .|.
IFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNE---LFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLE

TDPTERLTIMQFMNHPWI
 ||..|.|. |. |||||
VDPKKRYTCEQCLNHPWI

S_TKc MAPKAPK3.AA S_TKc 45-306 32 3.1e-94 320.31 SMART 1-231 (231) Show / Hide
Range on Protein: 45-306
Range on HMM: 1-231/231
Sequence Identity: 32% (91 aa)

YQLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEG--GELFSRIQERGD----Q
|..  ...| |  |||  |.|...|...|.| .    ..|.|.. . .  . |.||...||...      .| .|||...|  |.||..|..||     .
YEI-LRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

AFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDK-SCDMWSLGVIMYIL
 |.| .|. .|. |  |....||..| |||.||||.| ..     ..|..|||.|..       | | ||.|.|||||   .|.| .||.||.|.|.|..
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMN-------HPWI
||| |||.          | ..|.              |..||..|| .|. ||..|.|. . ..       |||.
LCGYPPFP------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MAPKAPK3.AA CDPK 118-306 46 5.9e-87 266.74 In-house 78-271 (271) Show / Hide
Range on Protein: 118-306
Range on HMM: 78-271/271
Sequence Identity: 46% (94 aa)

IVME--CMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDA----VLKLTDFGFAKETTQ------NALQTPC
||||    .||||| .|.|.|   |||.|||.||| |  |..  ||.|| |||.||||.|..||..|.     .|. |.| .|.  |      . . . |
IVMETEYCTGGELFDYIIEKGH--FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRC

YTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPW
 ||||.|||||    |...|| ||.|||.|||||| ||||  . | |       .. |.|||  ||| ..|..||.||| .| .||  |..  | ..|||
GTPYYIAPEVLQKK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIM----EKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPW

I
.
F

Kinase MAPKAPK3.AA RAD53 97-306 34 2.6e-81 241.86 In-house 64-305 (305) Show / Hide
Range on Protein: 97-306
Range on HMM: 64-305/305
Sequence Identity: 34% (84 aa)

PHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRI--QERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDA-----------
| |.||.|....     . . .|.| |.|||||..|  ..|    |.| .. .. . . .|.. ||...|.||| |||| |. .....            
PCIIRIYDIFDTP---QKYYYMVLELMTGGELFNKIVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDED

----VLKLTDFGFAKETTQNA--LQTPCYTPYYVAPEVLGPE---------------KYDKSCDMWSLGVIMYILLCGFPPFYSNTGQ-AISPGMKRRIR
    ..|.|||| .| ....   ..| | || ||||||.  .                | |..|.||.|.| ||.|||.|||    .|    . ..  |.
EISFLIKITDFGLSK-FVGEGSFMKTMCGTPQYVAPEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIK

L-GQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWI
  | |.|| |.| ..|| || ||. .|. ||..|.|| . .||||.
NQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM

Pkinase MAPKAPK3.AA Pkinase 45-306 31 2e-77 268.36 Pfam 1-293 (293) Show / Hide
Range on Protein: 45-306
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

YQLSKQVLGLGVNGKVLECYHRRSGQ----KCALKLLYDSPKARQ-----EVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGG----ELFSR
|.. ....| |  |.| .|.|. .|.    |.  |   .| | ..     |.  .    . |.|||..|..|.    |. . .|||..|||    .||..
YHI-GRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDY

IQERGDQAF--TEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYT-SKEKDAVLKLTDFGFAK---ETTQNALQTPCYTPYYVAPEVLG-PEKYDKS
|. . . .|  .|.|.  .|. |  .....||..| |||.||||.|.    . || .|..|||.||   .  .  ..|.| ||.|.||||.   ..|...
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

CDMWSLGVIMYILLCGFPPFYSNT----GQAISPGMKRRIRLGQYSFPNPEWLDVS-----------------EDAKQLIRLLLKTDPTERLTIMQFMNH
.||||.|.|.|..||| |||. .     . .    | .||. ....|. |.| ..|                 |..|..|. .|. ||..|.|..| ..|
VDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PWI
||.
PWF

Kinase MAPKAPK3.AA RSK 118-306 39 7.7e-74 251.62 In-house 78-278 (278) Show / Hide
Range on Protein: 118-306
Range on HMM: 78-278/278
Sequence Identity: 39% (82 aa)

IVMECMEGGELFSRIQERGD-QAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKD-AVLKLTDFGFAKE-TTQ--NALQTPCYTPYYVA
..||...||||| ..|...    |.|.||...|. |  |...||.. | ||| |||| ||.... . . .|||||||.|.   .  . ..|.|||  |.|
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEVLG---PEK-YDKSCDMWSLGVIMYILLCGFPPFYS---NTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLT-----IMQF
||.|    ... .||.|| |||||.|| .| |.|||..   |. . |.    .||. |..|.. |.|  .|..|| ||| .|. ||  ||.     . . 
PEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIM----KRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEI

MNHPWI
 .|||.
KQHPWF

Kinase MAPKAPK3.AA DCAMKL 97-306 42 2.5e-73 227.36 In-house 75-279 (279) Show / Hide
Range on Protein: 97-306
Range on HMM: 75-279/279
Sequence Identity: 42% (90 aa)

PHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTS-KEKDAVLKLTDFGFAKE
|||... ....   |    . .|||  .|| ||  | | .   ||||.|| .|.... |...||..|| |||.||||||      .   ||| ||| |..
PHIIQLYEHWDTETH----YYLVMEYVQGGDLFDAITENT--KFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACH

TTQ--NALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTE
 ..    | | | || |||||.|    |   .|.|..||| |||||||||| |  ..         |  |...|| |.| ..|  || ||. .|. ||  
VNGDFGPLYTVCGTPTYVAPEILMETGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEE--LFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEK

RLTIMQFMNHPWI
| |  | | |||.
RYTAEQIMQHPWV

Kinase MAPKAPK3.AA CAMKL 45-306 32 3e-73 233.06 In-house 1-297 (297) Show / Hide
Range on Protein: 45-306
Range on HMM: 1-297/297
Sequence Identity: 32% (98 aa)

YQLSKQVLGLGVNGKVLECYH-RRSGQKCALKLLY-----DSPKARQ---------------EVDHHWQAS--GGPHIVRILDVYENMHH---GKRCLLI
|.. | .|| |  |||  . | |  |.| | | .      . |....               |.  . . .  . |.|.....|.|.  |      .. .
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYL

VMECMEGGE--LFSRIQERGD--QAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT------QNALQTPCYTP
|||  .|||  || .|...|.  . ..|.||  . | |  |....||..|.||| ||||.| ... .  ..|..||||. . .       . | | | .|
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

YYVAPEVLGP--EKYD-KSCDMWSLGVIMYILLCGFPPFYSNT----GQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFM
 | |||..    ..|| .  |.||.|||.| ..||  ||   |    |.     ....|. | | .|   |..|| |...||| .|...|..| || | |
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

NHPWI
|||| 
NHPWM

Kinase MAPKAPK3.AA Ciliate-E2 97-306 27 1.4e-69 237.45 In-house 92-365 (365) Show / Hide
Range on Protein: 97-306
Range on HMM: 92-365/365
Sequence Identity: 27% (83 aa)

PHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQER----------GDQAFTEREAAEIMRDIGT---------------AIQFLHSRN-IAHRDVK
|.|... ......   . .. .|||  .||.||..|...          . . |||.|...||. |                 |...|||.| | ||| |
PNIIKMYECFQEK--DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIK

PENLLYTSKEKDAVLKLTDFGFAKETTQ---------------------------------NALQTPCYTPYYVAPEVLGPEK---------YDKSCDMW
|||.|.        .|..|||..|. ..                                 |  .| |.||.|.|||.|. .|         ||..||.|
PENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPE--------------WLDVSEDAKQLIRL----LLKTDPTERLT-IMQFMNHPWI
|||||.|..|.| |||             . |  ....||.||              |...|...|.||.     .|. || .|.| . | .||||.
SLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase MAPKAPK3.AA TyrKc 46-301 20 1.1e-10 -49.59 SMART 1-280 (280) Show / Hide
Range on Protein: 46-301
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

QLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQE----------V--DHHWQASGGPHIVRILDVYENMHHGK------RCLLIVMECMEGGE
   ...|| |  |.| ..  .   ...| | | ..   |..          .  .|       |.|||.. |     ...        |.|||| |..| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHH-------PNIVRLYGV---CTQQGRNFMYIEPLMIVMEYMPHGD

LFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQN-------ALQTP-----CY--TPY-YVA
| ......... .. ..  ... .|    ..|||.|. |||    | |....    . | .||| ... .            ..     .    |.   |
LKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEVLGPEKYDKSCDMWSLGVIMY-ILLCGFPPFYS-----NTGQAISPGMKRRIRLGQYSFPNPEWL----DVSEDAKQLIRLLLKTDPTERLT---IMQ
||..   |.    | || || |. |.  | .| .       . | .    |.. |. |   .  . .      .|  . ...   . || .| |   | .
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHE

FM
..
CF

Kinase MAPKAPK3.AA Pkinase_Tyr 116-169 28 0.000887 13.42 Pfam 82-137 (270) Show / Hide
Range on Protein: 116-169
Range on HMM: 82-137/270
Sequence Identity: 28% (16 aa)

LLIVMECMEGGELFSRIQER--GDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDV
..|||| |..| | .  ...  ..|..|  .  .. ..|  . ..|.|.|. |||.
IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase MAPKAPK3.AA DCAMKL 45-80 40 0.006207 4.35 In-house 1-36 (279) Show / Hide
Range on Protein: 45-80
Range on HMM: 1-36/279
Sequence Identity: 40% (15 aa)

YQLSKQVLGLGVNGKVLECYHRRSG-QKCALKLLYDS
||. . . | |    | || ||  | .|.|.|  | |
YQIGR-IIGDGNFAVVHECRHRETGDHKYAMKIRYQS

Kinase MAPKAPK3.AA RAD53 45-75 41 0.018272 2.57 In-house 1-30 (305) Show / Hide
Range on Protein: 45-75
Range on HMM: 1-30/305
Sequence Identity: 41% (13 aa)

YQLSKQVLGLGVNGKVLECYHRRSGQKCALK
| .|| .|| |  |.|...| .. .|| | |
YYMSK-ELGSGNFGTVKLAYEKKTCQKVAIK