MarkmA12

Species: Mouse
Alias: MarkmA12
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MarkmA12.AA Protein Sugen 521 None Fasta, JSON
MarkmA12.NA RNA Sugen 1563 None Fasta, JSON
MarkmA12.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 249 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of MarkmA12.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MarkmA12.AA MARK 39-287 50 2.6e-152 501.04 In-house 1-262 (262) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-262/262
Sequence Identity: 50% (131 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLV---KNK-PWFQEAMKEANILKKIKHPNIVSLLQVIE--TKTR-GYLILELVEGQELYEYIKTS--GH
||...|||||..||| ||.|..||. ||||..    .|.  |... | |..|.||..||||..|..|||  |...  |||.|...|.|||.|||    |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKG--NIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMV
..|. ||.|| ||.||| ||| ..|||||.||.||.|| .|  ||||||||.|....||. |...||.... ||| ||...|||.| |  .||||| .||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGKVPFDSFI--NPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
.|..|||     . ||......|.|.  | ||||...|..||.|| |..|||..|.|||||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase MarkmA12.AA CAMKL 39-287 39 2.2e-129 415.15 In-house 1-297 (297) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-297/297
Sequence Identity: 39% (117 aa)

YKVIRTIGHGTFAKVLLAQH-RLTGTSVAIKVLVKNKPWFQEAMK----------------EANILKKIK---HPNIVSLLQVIETKTR------GYLIL
|....|.|.|.|.|| ||.| |.||. ||||.. |.| |  . ||                |..|.|...   ||||..|..||||..        ||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVEGQE--LYEYIKTSGH----IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKG--NIKIIDFGLSTQFKP-----GEILKEHCGAYAFG
|...| |  |..||.  ||    ..|. ||..| ||.||| ||| |||||||.||.||..|..|  ||||||||.|....|     |. ||..|| ... 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APERFLG--QRYDGTKSDLGALGVVLHYMVVGKVPFDSFINP---------ELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
||| |.|  ..||| | |  ..||.|  ||.|..|||   ..         ...  .  . .| .. || ...||......| |..|||. ..|.|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase MarkmA12.AA CAMK 44-287 23 2.8e-109 353.39 In-house 1-425 (425) Show / Hide
Range on Protein: 44-287
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

TIGHGTFAKVLLAQHRLTG------------TSVAIKVLVKN-----------------------------KPWFQEAMKEANILKK-------IKHPNI
|.|.|.|.|| |..|..|.            . ||||.. |.                               . .. ..| .|.||       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLLQVIET-------------------KTRGYLIL---ELVEGQEL----YEYIKTSGH---------------IEEDKARQIFIQILSAVGYCHGHGI
..|..|.|.                   ... |...   |...| ||    ..||.  |.               ..|. ||..| ||.||| ||| |.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPDNIMIDNK-----------------GNIKIIDFGLSTQFKP------------------------GEILKEHCGAYAFGA-PERFLG------
|||||||.||..|..                 .||||||||....|.|                        |. .|. ||  .. | || ..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QRYDGTKSDLGALGVVLHYMVVGKVPFDSF-------------INPELQRQVVAGVYP-AHCG---------------VSKE--------LED
       ..|.| |.|  ..||.|  |..|. ||..                .|| ... .| |   .                 .|.|          |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLSRLMTVIPKYRPTATEVMKHPWL
|......| |. |.|......|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase MarkmA12.AA AMPK 39-287 42 1.5e-88 262.98 In-house 1-254 (254) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-254/254
Sequence Identity: 42% (109 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMK----EANILKKIKHPNIVSLLQVI-ETKTRGYLILELVEGQELYEYIKTSGHIEED
| .  ||| ||| || .. | |||. ||||.| | |   |. ..    |  |||...||.|. | .|| ||.|  ....| | | ||..||   | ..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

KARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGKVPF
 |.  | ||.|.| ||| |.|||||||| |. .| . |||| |||||   | || ||  ||     |||   |..| |.. |.   ||.|  |. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
|    |.| . ...|.|.    .|.| .||.... .| |  | |  ....|||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase MarkmA12.AA S_TKc 39-287 34 1.3e-86 294.92 SMART 1-231 (231) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-231/231
Sequence Identity: 34% (90 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMKEANILKKIKHPNIVSLLQVIETKTRGYLILELVEG--QELYEYIKTSGH------I
|...|.||.|.|.|| ...|. ||  ||||..       . ...| .|||| .||||| |. |... .. |...|...|   .|..|||  |.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

EEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGK
 |  || .. ||..|. ||| |||.||||||.||..|.  .|||.||||..|.      .  ||   . ||| .    |.. |.|  ..|..|  |..|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

VPFDSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMK-------HPWL
 ||.   ....  ...          |.|. |........ |. |||| |...       |||.
PPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MarkmA12.AA QIK 39-287 38 2e-83 283.48 In-house 1-272 (272) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-272/272
Sequence Identity: 38% (105 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVK---NKPWFQEAMKEANILKKIKHPNIVSLLQVIETKTRGYLILELVEGQELYEYIKTSGH------
| . |||| | || | ||.|| | | ||||.. |   ..  .|    |  |.| ..||.|. |.||.||.   |.. |  .. |...|.   |.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSD
              ..|..||..| ||.||| ||| ..|||||||  ||..||  ||||.|||.|  ||.|. |.  ||  .. ||| |.|. ||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

LGALGVVLHYMVVGKVPFDSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
   .||||  .| |. |||.   ..|.. |. | .     .|...|.|  . ..| |. | |   ...|.|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase MarkmA12.AA Pkinase 39-287 30 4e-78 270.65 Pfam 1-293 (293) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMK-----EANILKKIKHPNIVSLLQVIETKTRGYLILELVEGQ----ELYEYIK--TS
|...|.|| |.|..| ...|. ||  ||.|.. | .   .. .      |. |.|...||||| |. . |.|.. |...|..||     .|..||.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHI--EEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNI----KIIDFGLSTQ--FKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGAL
| .  .|. .. .. |||... ||| .||.||||||.||.|||.|.|    ||.||||. |    ... ..  || . . |||  .|..|.|.|.|  ..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLHYMVVGKVPFDSF------INPELQRQVVAGVYPAHCGVS---------------------KELEDLLSRLMTVIPKYRPTATEVMKHPWL
|..|..|. |. ||..          .. ...  . .. ..  .                     .|. |..... .. || ||||.....|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase MarkmA12.AA SNRK 39-287 40 2.8e-70 229.24 In-house 1-254 (254) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-254/254
Sequence Identity: 40% (104 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNK---PWFQEAMKEANILKKIKHPNIVSLLQVIETKTRGYLILELVEGQELYEYI-KTSGHIEEDK
| . .|.|.| || | ||.|  ||  ||.||. | |       . ..|   .| ..||||| |  ||.|.|. |||||| .| ..|.|| |    ..|| 
YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL

ARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNK-GNIKIIDFGLSTQFKPGEILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGKVPF
||. | ||. |. |||   .|||||||.|..  .| | .|. ||| | .|.||| |.  ||. |. |||  ||  ||    |. .|||.|. .| |..||
ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF

DSFINPELQRQVVAGVYPAHCGVSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
.   . |   ...   |     ||.|  ||. ...   || | .  |.  |.|.
QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV

Kinase MarkmA12.AA CAMK-Unique 39-287 25 4.6e-69 227.07 In-house 1-363 (363) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-363/363
Sequence Identity: 25% (91 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVK-----NKPWFQ----------------EAMKEANILKKIKHPNIVSLLQV----IETKT-------
|| .| ||||.| .|. .. | ||.  |.|.. |     .|   |                ....|..|.|. .||||. |...     ....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------RGYLILELVEGQELYEYIKT--------------------SGHIEE--DKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGN-----
        . |...|...| .|...|                       || .|    ...|. ..|||| | |  .|||||||..|||. . ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------IKIIDFGLSTQFK--PGE-ILKEHCGAYAFGAP--------------ERFLGQRYDGTKS---DLGALGVVLHYMVVGKVPFDSFINP-
           ||..||||....     . .... ||   . ||              |   .|.||.  |   |. .|||...|| .|. |||.  .. 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ELQRQVVAGVY-----PAHCG---VSKELEDLLSRLMTVIPKYRPTATEVMKHPWL
       |. .   .| |     ..  |   .|.|. |.. ..|||.|..| .| |  .|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase MarkmA12.AA Ciliate-E2 39-287 22 1.1e-68 234.52 In-house 1-365 (365) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YKVIRTIGHGTFAKVLLAQHRLTGT-----------------------SVAIKVLVKNKPWFQE----AMKEAN----------ILKKIKHPNIVSLLQV
||.|. || |.|..| ........                         .|.|.. ||.  ...     |.| |          ||....||||. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--TKTRGYLILELVEGQELYEYIK------------TSGHIEEDKARQIFIQILS---------------AVGYCHGHG-IVHRDLKPDNIMIDNKGN
 .  ...  ||..|...|..|..|||              . . | ....|. |||.               |. |.|  . |.|||.||.||..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKIIDFGLSTQFKP-----------GEILKEH----------------------CGAYAFGAPERFLGQRYDG--------TKSDLGALGVVLHYMVVGK
|||||||||.....           ....  .                      || . . ||| . |. ||.        .|.|. .|||.|..|. ||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

VPFDSFINPELQRQVVAGVYP------------------AHCGVSKELEDLLSR----LMTVIPKYRPT-ATEVMKHPWL
 ||        |.|   . .                    .  .|.|  ||...    .. . |. |.| . ....|||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase MarkmA12.AA Ciliate-E2-Unclassified 39-287 24 1.7e-67 230.53 In-house 1-352 (352) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSV-----AIKVLVKNKPWFQE---------AMKEAN-------------ILKKIKHPNIVSLLQVIETKTRGYLI
||.|..||.| |.|| ..||. ..  .     ..|. ....   ..         .|.. .             ||. ..||.|| .. . ..|   |..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LELVEGQELYEYIKTSGH-----------------IEEDKAR-----QIFIQILSAVGYCHGHG-IVHRDLKPDNIMIDNKG---NIKIIDFGLSTQFK-
.|..||..| .||| ...                 ..| .|.     ..| |||..  |.|  . |.|||.||.||..||.|   .|||||||.| . . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PGEILKEHCGAYAFG----APERFLGQRYDG---TKSDLGALGVVLHYMVVGKVPFDS---------------------FINPEL
               . ....  || . .     ||| . || ||.    |.|  .|||.|..|. |. ||..                     ...  .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

QRQVVAGVYP---AHCGVSKELEDLLS----RLMTVIPKYRPTATEVMKHPWL
|...    .|   .....|.| .|...    ... . |..|.|. ....|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase MarkmA12.AA TSSK 86-287 36 8.3e-62 201.63 In-house 68-289 (289) Show / Hide
Range on Protein: 86-287
Range on HMM: 68-289/289
Sequence Identity: 36% (80 aa)

ILKK-IKHPNIVSLLQVIETKT-RGYLILELVEGQELYEYIKTS------GHIEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDF
|..| .|||||. ... .||   . |...|. |.  | |||...      | ..|..||. | |. ||| |||.|..||||||  ||  |  .|||..||
IMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDF

GLSTQFKPGE------ILKEHCGAYAFGAPERFLGQRYDGTKSDLGALGVVLHYMVVGKVPFDS---FINPELQRQV-VAGVYPA--HCGVSKELEDLLS
| .  .....       .|  || ||  ||| ..|  ||. ..|  ..||.|. ||.|. |||     |.  |..|      .|.  .|..|.|  ||..
GFARYWPRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIR

RLMTVIPKYRPTATEVMKHPWL
....  |. ||...|...|.|.
HMLQPHPCNRPHINEICHHCWM

Kinase MarkmA12.AA Pkinase_Tyr 39-180 25 7.9e-20 67.77 Pfam 1-158 (270) Show / Hide
Range on Protein: 39-180
Range on HMM: 1-158/270
Sequence Identity: 25% (40 aa)

YKVIRTIGHGTFAKVLLAQHR----LTGTSVAIKVL--VKNKPW--FQEAMKEANILKKI-KHPNIVSLLQVIETKTRG---YLILELVEGQELYEYIKT
 . ....|.| | .| ..  .     |.. ||.|.|     ..    .. |.||.|.|.. .|||||.|. |.  . .    |...|....  |..| ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----SGHIEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLS
     ...      |. .|| ..  | . ....||||   |....... .|| ||||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase MarkmA12.AA TyrKc 39-287 21 2.4e-16 41.7 SMART 1-280 (280) Show / Hide
Range on Protein: 39-287
Range on HMM: 1-280/280
Sequence Identity: 21% (61 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTSVAIKVLVKNKPWFQEAMKEANILKKI--KHPNIVSLLQVIETK-------TRGYLILELVEGQELYEYIKTSGH
 . ....|.| | .| ... .   . ||.|.| ...   .. |.||.|..|.  .||||| |. |. ..          ....|....  | .|.. ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-IEEDKARQIFIQILSAVGYCHGHGIVHRDLKPDNIMIDNKGNIKIIDFGLSTQFKPG-------EILKE----HC---GAYAFGAPERFLGQRYDGTKS
 .  ..  .. .|| .   | | ....||||   |....... .|| |||||   . .       .  .     ..     .   ||| .   ..  |||
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS

DLGALGVVLHYMV-VGKVPFDS-----FINPELQRQVVAGVYPAHCGV---------SKELEDLLSRLMTVIPKYRPTATEVMKHPWL
|  . ||..  .   |. |          | |. ..| .| ..              ..|. .. ..     |. ||| .|.  |  .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase MarkmA12.AA TSSK 39-69 29 7.6e-08 21.82 In-house 1-47 (289) Show / Hide
Range on Protein: 39-69
Range on HMM: 1-47/289
Sequence Identity: 29% (14 aa)

YKVIRTIGHGTFAKVLLAQHRLTGTS----------------VAIKV
|.| ..||||..||| .|... .                   ||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKI

Kinase MarkmA12.AA APH 153-181 24 0.000195 16.01 Pfam 171-203 (248) Show / Hide
Range on Protein: 153-181
Range on HMM: 171-203/248
Sequence Identity: 24% (8 aa)

GIVHRDLKPDNIMID-NKGNIK---IIDFGLST
...|.|..|.|.|.| . .. .   .||.. ..
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDAC

UBA_CAMKL MarkmA12.AA UBA_CAMKL 307-344 39 9.2e-13 43.92 In-house 1-41 (41) Show / Hide
Range on Protein: 307-344
Range on HMM: 1-41/41
Sequence Identity: 39% (16 aa)

DPDIVDAMQYI--GFRAKDIRESLTEEKF-NEMSAAYYLLE
|..|.. |. .  ||  ..|.||| . |. |...|.|||| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL