Gene MarkmA5 (Mouse)
MarkmA5
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmA5.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 249 | Kinase domain by global Sugen HMM | Fasta, JSON |
| MarkmA5.NA | RNA | Sugen | 1724 | None | Fasta, JSON |
| MarkmA5.AA | Protein | Sugen | 559 | None | Fasta, JSON |
Protein domains of MarkmA5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmA5.AA | MARK | 83-331 | 50 | 4.7e-168 | 553.24 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-262/262 Sequence Identity: 50% (133 aa) YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIR---KSE-CWCNPVMSEVELLMMADHPNIISLLQVIE--TKKK-VYLIMELCEGKSLYQHIRNA--GY | || |||||...|| ||.|..|| .||.|.. ... .|...||.|.|.... ||||||.|..||| |... .|||||...|..||..|... |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDG--KVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMV |.|.|||..|.|..||.||||...|||||.||.||.. ..| ..||||||......|||||| ||||.|. |||..|..||||||.|.|.||||||||| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGKVPFDAAS--IQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWV .|..|||... . .| ..||.||| .|...|.|.|.||..|.|.||. |||. |.| |||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmA5.AA | CAMKL | 83-331 | 38 | 9.20000000001e-141 | 452.03 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-297/297 Sequence Identity: 38% (115 aa) YVMLETIGHGGCSKVMLARH-RLTGSHVAVKMIRKSECWCNPVMS----------------EVELLMMAD---HPNIISLLQVIETKKK------VYLIM | ...|.|.|...|| ||.| |.|| .||.|.| |. .|..|.|. |.....| . |||||.|..||||... .||.| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELCEGKS--LYQHIRNAGY----LQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDG--KVKIIDFGLGTQVKP-----GQKLNLFCGTYPFS |.|.| . |...|.. |. ..|.||| .|.|..||.||||..||||||.||.||.. ..| ..||||||.... .| ||||. |||..|. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEVLLS--RPYDGPKIDVWTLGVVLYFMVTGKVPFDAASI--------QKLVRQILAGKYF-VPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWV |||.... .||||||.|.| .||.||.||.|..|||.... .. ... .|. .....| ..||||. ... ||. |||. ..| |||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmA5.AA | CAMK | 88-331 | 25 | 4.2e-123 | 398.75 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 88-331
Range on HMM: 1-425/425
Sequence Identity: 25% (108 aa)
TIGHGGCSKVMLARHRLTG------------SHVAVKMIRKS-----------------------------ECWCNPVMSEVELLMM-------ADHPNI
|.|.|. .|| |..|..|. .||.|.| |. .... |..|.|.... |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
ISLLQVIE------------TKKK--------VYLIM---ELCEGK----SLYQHIRNA---------------GYLQEDEARALFKQLLSAMNYCHNQG
|.|..|.| | .| .|..| |.|.| |...|. |...|.||| .|.|..||..|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IVHRDLKPDNIMVEKD-----------------GKVKIIDFGLGTQVKP------------------------GQKLNLFCGTYPFSA-PEVLLS-----
||||||||.||.. .. ...||||||. ....| |||.. |||| .. | ||||..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------RPYDGPKIDVWTLGVVLYFMVTGKVPFDAA-------------SIQKLVRQILAGKY-FVPSRLSV-----------------------ELR
.||.|||.|.| .||.||.|..|. ||.. ....| ..|..||| | |. .| | .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DLISLLMTANPKLRPTVAEVMVHPWV
|||. ... .|. |.|..... |||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmA5.AA | S_TKc | 83-331 | 34 | 1.9e-100 | 340.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-231/231 Sequence Identity: 34% (90 aa) YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKSECWCNPVMSEVELLMMADHPNIISLLQVIETKKKVYLIMELCEG--KSLYQHIRNAGY------L | .|..||.|. .||...||. || .||.|.|. . ...|...|.. .||||. |. |... ...|..||.|.| .|...|.. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF QEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGK | .|| ...|...|..|||..||.||||||.||.. . .||.|||| .|. . |||| . ||||| .|...|.|.| .|..|| |..|. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY VPFDAASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMV-------HPWV ||. .|.. ..|. | |..|.|. ... .|. |||. |.. |||. PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmA5.AA | AGC | 83-331 | 21 | 6.2e-94 | 242.58 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-395/395 Sequence Identity: 21% (87 aa) YVMLETIGHGGCSKVMLARHR------LTGSHVAVKMIRKSE-CWCNP------VMSE------------VELLMMAD----------HPNIIS-LLQVI . .| .|| |. .||.|.|.. || |.|...|.. .. .|.| . |.... ||.|.. | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF ETKKK--VYLIMELCE---------GK-SLYQHIR---NAGYLQEDEARALFKQ-------LLSAMNYCHN-QGIVHRD-LKPDNIMVEKDGKVKIIDFG ..|.. .|..||... | |..|.. . |.. |..|| . . ...|. | |. .||.||| |||.||. .|| .|. ||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LGTQVKPG---------------------------------------------------QKLNLFCG--TYPFSAPEVLLSRPYDGPKIDVWT--LGVVL | .... . .. . ||| | . |||.| |. | |. ||... LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM YFMVTGKVPFDAASIQ----------KLVRQILAGKYFVPSR----------------LSVELRDLISLLMTANPKLRPT----------VAEVMVHPWV | |.||. || . . | .. .|. |.|| . . .|.|..|||. |.. .|. |.. . |.. ||| YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | MarkmA5.AA | NuaK | 83-331 | 38 | 6.3e-94 | 247.27 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 83-331
Range on HMM: 1-252/252
Sequence Identity: 38% (98 aa)
YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKSECWCNPVMS----EVELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDE
| ...| | | || ||. . || ||.| |.|. . | |.|.. .||.||. | | | |. ..|| | || | . . | | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE
ARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKVPFD
|| .| | ||. ||| .|.||||| ||. ... .|| |||| . .. |. ||| . ||. .|| || .| | |||.|| || | |||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD
AASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWV
..||.|| |.|. | . |. . || ... ||. | |. .. |.||
GHDFKHLVKQISQGAYYEPCKPSDA-CMLIRWMLMVNPRRRATIYDICHHWWV
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| Kinase | MarkmA5.AA | Pkinase | 83-331 | 30 | 1.9e-89 | 308.25 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-293/293 Sequence Identity: 30% (89 aa) YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKSECWCNPVMS-----EVELLMMADHPNIISLLQVIETKKKVYLIMELCEGK----SLYQHIR--NA |. ...|| |. ..| ...|. || |||| |.|.. .. .. |.... . .||||. |. . |.|...|..||.||| .|. .|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GYL--QEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKV----KIIDFGLGTQ--VKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTL | . .|.|.. ..|.|....|||..||.||||||.||.. ..| . ||.|||| | ... .. ||||... ||||.....|.|||.|.| . GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVVLYFMVTGKVPFDAA------SIQKLVRQILAGKYFVPSRLS---------------------VELRDLISLLMTANPKLRPTVAEVMVHPWV |..|| |..|. ||. . . ......|. ... .. . |..|.|. . . .|| ||| .... |||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmA5.AA | AMPK | 83-331 | 38 | 5.6e-88 | 261.29 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-254/254 Sequence Identity: 38% (97 aa) YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRK----SECWCNPVMSEVELLMMADHPNIISLLQVI-ETKKKVYLIMELCEGKSLYQHIRNAGYLQED |.. .||| | || .. | ||| ||.| . | .. . . .|...| . ||.|| | .|| ||.. ...|| | |. | | |||. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER EARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKVPF ||. .|.| .|. |||. .|||||||| |. .. ..|| |||| | |..| || |||. ...| ||..|.| ||.|| |. |. || EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF DAASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWV | .. .| . |..|.| .|. || | .|||. . . .| | |. ... ||| DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MarkmA5.AA | QIK | 83-331 | 37 | 2.8e-86 | 292.95 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 83-331
Range on HMM: 1-272/272
Sequence Identity: 37% (101 aa)
YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKS---ECWCNPVMSEVELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGY------
| . ||| | | ||||| | . ||.| | || | . . ||... | .||.|| |.||.||.. |...| |.. .. .. . |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV
--------------LQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKID
..|.||| |.|..|| |||...||||||| ||. .. .||.|||.. |.|| |. .||. |. |||... . |||||.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD
VWTLGVVLYFMVTGKVPFDAASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWV
.| .||||| .|.|. ||| ..|.| . .| ||. .| .|... .|| .. .|. | |.. .. |.|
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmA5.AA | SNRK | 83-331 | 42 | 1.5e-80 | 263.43 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-254/254 Sequence Identity: 42% (109 aa) YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKS---ECWCNPVMSEVELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHI-RNAGYLQEDE | . .|.|.| | |||| || .||||.| | | .. || . . ||||. | ||.|. |.|||.|| .| .| .| . |.|| YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL ARALFKQLLSAMNYCHNQGIVHRDLKPDN-IMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKVPF || |.|.. |..||| .|||||||.| . || | ||. ||| . .||.||. .|| .||||.|| || | .|.| |||.|| .| |..|| ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF DAASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWV . | . .|. || ||...| | |||| .. .|| | .. |. |.|| QEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MarkmA5.AA | Ciliate-E2 | 83-331 | 23 | 9.3e-79 | 267.96 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 83-331 Range on HMM: 1-365/365 Sequence Identity: 23% (87 aa) YVMLETIGHGGCSKVMLARHRLTG-----------------------SHVAVKMIRKS--ECWCN--PVMSEVE----------LLMMADHPNIISLLQV | .. || |. ..| ........ . .|.|...|. | . . .| |.. .| .||||| . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TKKKVYLIMELCEGKSLYQHIRNA-----------GYLQEDEARALFKQLLS---------------AMNYCHNQG-IVHRDLKPDNIMVEKDGKV . .....||.||.|.|..|...|.| .|. | |.. ..||.|. |..|.|... |.|||.||.||.. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KIIDFGLGTQVKPGQKLNL--------------------------------FCGTYPFSAPEVLLSRPYDG--------PKIDVWTLGVVLYFMVTGKVP ||||||| ..... .. .. .|||... |||.| . .||. |.|.| |||.||.|..|| | KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FDAASIQKLVRQILAGKYFVP------------------SRLSVELRDLISL----LMTANPKLRPT-VAEVMVHPWV | .||. .|. | .| | |||. .. .|. |.| ... ||| F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | MarkmA5.AA | Ciliate-E2-Unclassified | 83-331 | 23 | 3.7e-72 | 246.05 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 83-331
Range on HMM: 1-352/352
Sequence Identity: 23% (84 aa)
YVMLETIGHGGCSKVMLARHRLTGSHV-----AVKMIRKSECWCNPV---------MSEVE-------------LLMMADHPNIISLLQVIETKKKVYLI
| ....||.|| .|| ...|. .. . . |.. .. . . . | . . .| . .||.|. .. . ..|...|..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV
MELCEGKSLYQHIRN-----------------AGYLQEDEAR-----ALFKQLLSAMNYCHNQG-IVHRDLKPDNIMVEKDG---KVKIIDFGLGTQVK-
||.|||..| |.|.. ..| .|. .|.|.|.. .|.| .. |.|||.||.||.. ..| ..||||||. . .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------------PGQKLNLFCGTYPFS----APEVLLSRPYDGP---KIDVWTLGVVLYFMVTGKVPFDAASIQK----------------LVRQIL
. |... ||||. . ||||| . ||.. |.|.|.|||.||.|..|. ||.. . . | ..|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK
AGKYFVPS--------RLSVELRDLIS----LLMTANPKLRPTVAEVMVHPWV
......|. ..| | |.|. .. ||. |.| ... |||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | MarkmA5.AA | TyrKc | 83-330 | 21 | 1.5e-16 | 44.88 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 83-330 Range on HMM: 1-280/280 Sequence Identity: 21% (61 aa) YVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKSECWCNPVMSEVELLMMA--DHPNIISLLQVIETK-------KKVYLIMELCEGKSLYQHIRNAGY ......|.| .|.... . |||||.... |.| ..... .||||. |. |. .. . ....||.... .| ...|. . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPG------QKLNLF----CGT--YPF--SAPEVLLSRPYDGPKI |. .. | . |.| | ....|||| |..| ... ||| |||| .. . .. .| | |||.. . . .| KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS DVWTLGVVLYFMVT-GKVPFDA-----ASIQKLVRQILAGKYFVPSRL---------SVELRDLISLLMTANPKLRPTVAEVMVHPW ||| ||... . | |. | | | ..... .|.. . . |. .... ..|. ||| .|. .. . DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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| Kinase | MarkmA5.AA | Pkinase_Tyr | 83-223 | 25 | 8.7e-15 | 50.71 | Pfam | 1-157 (270) | Show / Hide |
Range on Protein: 83-223 Range on HMM: 1-157/270 Sequence Identity: 25% (40 aa) YVMLETIGHGGCSKVMLARHR----LTGSHVAVKMIRKSECWCNP-----VMSEVELLMMA-DHPNIISLLQVIE-TKKK--VYLIMELCEGKSLYQHIR ......|.| .|.... . |. .|||||. | . |.|..... .||||..|. |. .. .|..||.... .|. . | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR N----AGYLQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGL . . | . | ..|.| ......|||| |..|.....||| |||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL |
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| Kinase | MarkmA5.AA | APH | 174-222 | 18 | 0.000245 | 15.67 | Pfam | 151-200 (248) | Show / Hide |
Range on Protein: 174-222 Range on HMM: 151-200/248 Sequence Identity: 18% (10 aa) LQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVE-KDGKVK---IIDFG .|.. .. |. .|.... ...|.|..|.|.|. ... . .||.. RQWWLWQRLWAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWD |
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| UBA_CAMKL | MarkmA5.AA | UBA_CAMKL | 351-388 | 34 | 6.8e-12 | 40.84 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 351-388 Range on HMM: 1-41/41 Sequence Identity: 34% (14 aa) NPAIVKAMGYI--GFQAQDIEDSLRQRKF-NETMASYCLLK .. |.. | . ||. ..|..|||..|. |. .| |.|| DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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