Gene MarkmD1 (Mouse)

MarkmD1

Species: Mouse
Alias: MarkmD1
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MarkmD1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 249 Kinase domain by global Sugen HMM Fasta, JSON
MarkmD1.AA Protein Sugen 1142 None Fasta, JSON
MarkmD1.NA RNA Sugen 3429 None Fasta, JSON

Protein domain

Protein domains of MarkmD1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MarkmD1.AA MARK 19-267 47 2.4e-156 514.38 In-house 1-262 (262) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-262/262
Sequence Identity: 47% (125 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLE---KDK-KNATLISNELEIMRLVDHPNITKLFHVME--TTEH-ICMVMEYASGGDLAGRIIEV--SY
|..|||.|.|..|.||||.|.||...||.|..|   ... ..   .  |.|||...|||||.|||||.|  |..| |...|||||||.| ..|...   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IHEEEARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANR--NIKLCDFGLAIKVNTEQKSTVFCGTLPYCAPELFNIQSYDPRALDIWSMGVVLYIMV
.||||||.||.|||.||.|||...|.||||||||||.|.|.  |||..|||..|.....|| . ||||.||.|||.|. . || .. ||||.|||||.||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TKHYPFKATT--YDKMKEEMQDPHYYIPPKLPAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
. ..||...|  | ....... ..| ||....... ||| .|.|..| .||.| ..|.| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase MarkmD1.AA CAMKL 19-267 38 1.7e-136 438.17 In-house 1-297 (297) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-297/297
Sequence Identity: 38% (115 aa)

YRVLKTLGTGNFAQVKLAVH-LHTEVQVALKTLEKDKKN-ATLISN---------------ELEIMRLVD---HPNITKLFHVMETTEH------ICMVM
||..||||.|.|..||||.| ..|...|| | ..|.|..  . ...               | .||....   |||| ||..|.|| ||      |..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGD--LAGRIIEVSY----IHEEEARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANR--NIKLCDFGLA---IK--VNTEQKSTVFCGTLPYC
||.|||.  |  .|..  .    ..|.|||..|.|||.||.|||..||.|||||||||| | |   |||..|||..   ..  ....|| . |||..||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFNI--QSYDPRALDIWSMGVVLYIMVTKHYPFKATTY--------DKMKEEMQDPHYY-IPPKLPAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
|||.|.   ..|| .. ||||.||.|| ||. ..||.. ||         .....|.. .|. |.....    .|| .. . .| .||.| ..|.| |.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase MarkmD1.AA CAMK 24-267 25 1.8e-114 370.39 In-house 1-425 (425) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-425/425
Sequence Identity: 25% (108 aa)

TLGTGNFAQVKLAVHLHTE------------VQVALKTLEKD-----------------------------KKNATLISNELEIMRL-------VDHPNI
|||.|.|..|||..| .|             ..|| | ..|.                              |.   . .|.|||..       .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TKLFHVME------------TTEH--------ICMVM---EYASGG----DLAGRIIEVSY---------------IHEEEARHIFTQIVCAVSYCHENG
 ||..|.|            | ..        ..|||   ||.|||    ||  .|.| ..               ..|.|||..| ||..|| |||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDIKPENILMDAN-----------------RNIKLCDFGLAIKVNT------------------------EQKSTVFCGTLPYCA-PELFNI-----
|.|||.||||||.| |                  |||..|||.|.|..                          || . ||||..|.| ||..|      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QSYDPRALDIWSMGVVLYIMVTKHYPFKAT-------------TYDKMKEEMQDPHYY-IPPKLPA-----------------------HIA
        . |.... |.||.||.||||.. ..|| .              .. ...|  .   |. .||...                           
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLIVQLFTIDPVQRPKIGDVMEHQWL
.|| .. . || .|..| ....|.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MarkmD1.AA S_TKc 19-267 33 1.1e-97 331.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEKDKKNATLISNELEIMRLVDHPNITKLFHVMETTEHICMVMEYASG--GDLAGRIIEVSY------I
|..|...| | |..|....| .|  .||.| .         | .|..|..  .|||| ||. |... .|..|||||..|  |||  .| .  .      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

HEEEARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNIKLCDFGLAIKVNTEQKSTVFCGTLPYCAPELFNIQSYDPRALDIWSMGVVLYIMVTKH
.| .||... ||.||. |||..|| |||.||||||.|   .||.|||||| ..      | ||||. |.|||..   .|.... |.|| |..||.|..  
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

YPFKATTYDKMKEEMQDPHYYIPPKLPAHIANLIVQLFTIDPVQRPKIGDVME-------HQWL
 ||   ....| . .           .    ..| .... || .|| . ....       |.|.
PPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MarkmD1.AA AGC 19-267 21 1.4e-94 244.31 In-house 1-395 (395) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-395/395
Sequence Identity: 21% (85 aa)

YRVLKTLGTGNFAQVKLAVHLH------TEVQVALKTLEKDK-----K--NATLISNE------------LEIMRLVD----------HPNITK-LFHVM
...||..|.| | .| |. . .      |. . |.| |.|..     |      . .|             .|. ...          ||.|.| |..  
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETTEH--ICMVMEYAS---------GG-DLAGRII---EVSYIHEEEARHIFTQ-------IVCAVSYCHE-NGIAHRD-IKPENILMDANRNIKLCDFG
.. .|  ...||||..         || .|  ..       .  ||.||... .       ||.|. | |. .|| ||| .||||||.|.. .|||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAIKVNTE---------------------------------------------------QKSTVFCG--TLPYCAPELFNIQSYDPRALDIWS--MGVVL
|. .....                                                   .. . |||  |  | ||| .    |. .| |.||  .|...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YG-KACDWWSFGLGCLM

YIMVTKHYPFKA--------------TTYDKMKEE----MQDPHYYIP--------PKLPAHIANLIVQLFTIDPVQRPK----------IGDVMEHQWL
| |.| . || .               ...| ..     ......  |        ...     .|| .|.. || .|.           . ....| | 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase MarkmD1.AA NuaK 19-267 40 8.8e-94 246.88 In-house 1-252 (252) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-252/252
Sequence Identity: 40% (102 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEKDKKNATL----ISNELEIMRLVDHPNITKLFHVMETTEHICMVMEYASGGDLAGRIIEVSYIHEEE
|...|||| | .  ||||.  .|  .|| |.  |.|  .      |  | |||  ..||.| . . | |  . | .||||||||.|   | | . . |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNIKLCDFGLAIKVNTEQKSTVFCGTLPYCAPELFNIQSYDPRALDIWSMGVVLYIMVTKHYPFK
|||.| ||| || ||| ..|.||| | ||||.|.| |.|  ||||    . ..  . |||   |  ||  | | |     | ||.||.||.|| .  || 
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

ATTYDKMKEEMQDPHYYIPPKLPAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
   . ...   .  .|| |.| |     || .. ...| .|  | |. .| |.
GHDFKHLVKQISQGAYYEPCK-PSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase MarkmD1.AA AMPK 19-267 38 3.5e-86 255.86 In-house 1-254 (254) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-254/254
Sequence Identity: 38% (98 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEKDK----KNATLISNELEIMRLVDHPNITKLFHVM-ETTEHICMVMEYASGGDLAGRIIEVSYIHEE
| . ||.|.| |  ||...|  |  .||.| |.|.|    .    |..|..|..|. ||.|..|. |  ||.. | |||||.|||.|   |.    . |.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNIKLCDFGLAIKVNTEQKSTVFCGTLPYCAPELFNIQSYDPRALDIWSMGVVLYIMVTKHYPF
||.  | ||. .|.|||...|.||| ||||.|.|.| |||. ||||    .  ..    ||   | |||.   . |  .  |||| ||.|| |.    ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

KATTYDKMKEEMQDPHYYIPPKLPAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
      .      . .||||  |   ...|| .. . ||..| .| |...|.|.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase MarkmD1.AA QIK 19-267 36 5.8e-86 291.89 In-house 1-272 (272) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-272/272
Sequence Identity: 36% (100 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEK---DKKNATLISNELEIMRLVDHPNITKLFHVMETTEHICMVMEYASGGDLAGRIIEVSY------
| . .|.| |||| |||| |  |  .|| | . |   |..| . .  | .|| . .||.|.||. |||| . . .|.||.|.|..   ...         
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------IHEEEARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNIKLCDFGLAIKVNTEQKSTVFCGTLPYCAPELFNIQSYDPRALD
              . |.||| .|.||. || |||. .|.|||.| ||||.|.| |||. |||.     ..|    .||. || |||.|  ..||   .|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

IWSMGVVLYIMVTKHYPFKATTYDKMKEEMQDPHYYIPPKLPAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
|||||||||..|.   ||   |  .... .    . ||. ..   . || .  ..|| .|  |  ...|.|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase MarkmD1.AA NIM1 19-267 38 7e-86 252.27 In-house 1-258 (258) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-258/258
Sequence Identity: 38% (99 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLE--K---DKKNATLISNELEIMRLVDHPNITKLFHVMETTEHICMVMEYASGGDLAGRIIEVSYIHEE
||. . .| ||| .|||.||  |   || | .   |   | |   . | |   |  . |||| .|. | ||   .  |||||.|| | ..| .   . | 
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

EARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNIKLCDFGLAIKVNT----EQKSTVFCGTLPYCAPELFNIQSYDPRALDIWSMGVVLYIMVTK
..  || ||| ||.  |...| ||||| ||..  .|  .|. |||    .      .|.   |||  || |||||  ..|     |.|  |. || |.| 
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

HYPFKATTYDKMKEEMQDPHYYIPPKLPAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
  ||.| |  |||    .  | ||. .      ||      .| ||. | ..| |||.
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase MarkmD1.AA Pkinase 19-267 29 2.6e-84 291.23 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEKDKKNATLISN-----ELEIMRLVDHPNITKLFHVMETTEHICMVMEYASGG----DLAGRII---E
|......| |.|..|....|  |. .||.|...|....     .     |..||. ..|||| .|....|.  ||.|||||. ||    ||. .|    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VSY-IHEEEARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNI----KLCDFGLAIK--VNTEQKSTVFCGTLPYCAPELFNIQSYDPRALDIWSM
 ..   |.|......||.... |||..|| |||.||||||.| | .|    |.|||||| .      .  |.||||..|.|||. . ..|.... |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLYIMVTKHYPFKAT------TYDKMKEEMQDPHYYIPPKLP---------------------AHIANLIVQLFTIDPVQRPKIGDVMEHQWL
|..||.|.... ||.        . ..| ..  .| .  .   .                          .|  ... || .|| . ....| |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MarkmD1.AA Ciliate-E2 19-267 24 3.9e-75 255.93 In-house 1-365 (365) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-365/365
Sequence Identity: 24% (90 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQ-----------------------VALKTLEKD----KKNATLIS----------NELEIMRLVDHPNITKLFHV
| ..| .|.|||..|... .  .  |                       .|.|...|.    .|.   |           ||..|.....|||| |.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ME--TTEHICMVMEYASGGDLAGRIIEV-----------SYIHEEEARHIFTQIVC---------------AVSYCHENG-IAHRDIKPENILMDANRNI
 .  ....| .||||..||||  .|..             |. |.|...|..||.                |. |.|... | ||||||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLCDFGLAIKVNTE--------------------------------QKSTVFCGTLPYCAPELFNIQSYDP--------RALDIWSMGVVLYIMVTKHYP
|..||||. |....                                .    .|||..| ||| .| ..||          . ||||.||.||.|... .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FKATTYDKMKE--------EMQDPHYY-------IPPKLPAHIANLIVQ----LFTIDPVQRPK-IGDVMEHQWL
|    ... |.        |.|.. ..       .. |..    .|| .    ..  || .|.  . ....|.|.
F----QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MarkmD1.AA Ciliate-E2-Unclassified 19-267 23 3.7e-69 236.06 In-house 1-352 (352) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-352/352
Sequence Identity: 23% (82 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEKDKKNATLISNE--------LEIMRL------------------VDHPNITKLFHVMETTEHICMVM
|...|..|.|.|..|....|  .  . |.|.. | .... .. ..        .|....                   .||.| |.|.. .....|..||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYASGGDLAGRIIEVSY-----------------IHEEEAR-----HIFTQIVCAVSYCHENG-IAHRDIKPENILMDANR---NIKLCDFGLAIKVNT-
||. ||||   | . .                  . |..|.     ..| ||... .|.|... | ||||||||||.| |    .||..|||...| .. 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------EQKSTVFCGTLPYC----APELFNIQSYDPR---ALDIWSMGVVLYIMVTKHYPFKATTYDK----------------MKEEMQD
               .|... ||||. |     |||..  | || .   . ||||.||.|| |..  |||.......                .... ..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

PHYYIPP--------KLPAHIANLIV----QLFTIDPVQRPKIGDVMEHQWL
  ...|.        ... . ...|     ...  .| .|. . ....|.|.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase MarkmD1.AA TyrKc 19-267 23 1.3e-20 75.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

YRVLKTLGTGNFAQVKLAVHLHTEVQVALKTLEKDKKNATLISNELEIMRLV--DHPNITKLFHVMETT-------EHICMVMEYASGGDLAGRIIEVSY
 . .|.|| |.| .| ...     .||| |.| .|.     . .|..||. .  .|||| .|. |  .        | ...||||...|||  .. .   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-IHEEEARHIFTQIVCAVSYCHENGIAHRDIKPENILMDANRNIKLCDFGLAIKVNTE------QKSTVF----CGT--LPY--CAPELFNIQSYDPRAL
 .  ..  .. .|| |  .| |.... |||.   |.| ..|. .| .||||. ..  .      ..  .     .|   ||.  .||| .|   . . . 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS

DIWSMGVVLYIMVTKHYPFKA------TTYDKMKEEMQDPHYYIPPKL---------PAHIANLIVQLFTIDPVQRPKIGDVMEHQWL
|.|| ||... . |   .          . . . |  .. ..  .|.          |. . ... |    || .||   ..  |. .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MarkmD1.AA Pkinase_Tyr 19-100 30 8.1e-18 60.97 Pfam 1-94 (270) Show / Hide 
Range on Protein: 19-100
Range on HMM: 1-94/270
Sequence Identity: 30% (29 aa)

YRVLKTLGTGNFAQVKLAVHL----HTEVQVALKTL--EKDKKN---ATLISNELEIMRLV-DHPNITKLFHVME-TTEH--ICMVMEYASGGDL
 . .|.|| |.| .|....       |...|| |.|    ....   . ... |..||.   .|||| .|  |     |.  |..||||. .|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase MarkmD1.AA Pkinase_Tyr 143-167 42 0.028247 8.33 Pfam 141-166 (270) Show / Hide 
Range on Protein: 143-167
Range on HMM: 141-166/270
Sequence Identity: 42% (11 aa)

NILMDANRNIKLCDFGLAIKV-NTEQ
|.| . |. .| ||||||  . |...
NCLVTENNVVKICDFGLARDIYNDDY
UBA_CAMKL MarkmD1.AA UBA_CAMKL 288-325 34 5.2e-13 44.8 In-house 1-41 (41) Show / Hide 
Range on Protein: 288-325
Range on HMM: 1-41/41
Sequence Identity: 34% (14 aa)

NPSIVAAMRTM--GYNPKDITDSLYKKKF-NSIMATYLILK
...|.. |..|  |.....|..|| . |. | |.|||..| 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL
UBA MarkmD1.AA UBA 288-325 15 0.000188 22.04 SMART 1-38 (38) Show / Hide 
Range on Protein: 288-325
Range on HMM: 1-38/38
Sequence Identity: 15% (6 aa)

NPSIVAAMRTMGYNPKDITDSLYKKKFNSIMATYLILK
. .... .. ||..   . ..|.. . |  ||..... 
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS