Gene MarkmD3 (Mouse)
MarkmD3
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| MarkmD3.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 250 | Kinase domain by global Sugen HMM | Fasta, JSON |
| MarkmD3.AA | Protein | Sugen | 477 | None | Fasta, JSON |
| MarkmD3.NA | RNA | Sugen | 1434 | None | Fasta, JSON |
Protein domains of MarkmD3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MarkmD3.AA | MARK | 14-263 | 41 | 9.80000000001e-139 | 456.0 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-262/262 Sequence Identity: 41% (109 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLE---KNI-NSMADITSKVELLQSLEHRNIVRFFHMID--TLTT-TYVIMEYVPGEDLEKYLRAL--GC ..|| .|.||...||||||..|...||.|..| .| ..| . . .|....|.| ||...||.|. | .. .|.||||..| .| |..| |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LKEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAAR--NAKLSDFGMAIKTTEGQMLEETCDSLLYRAPEILARKPYDGLAVDMWSLGIVLYVLV |.||||| |.|.||||... ...|.|| ||.||||.|. . |.|..|||..|. ..||.|.. | .. | ||||. .||||| .||.||||.|||..| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGHFPYVEAT--IEYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL .|.||. ..| .. ... |.. ... || |.| |. .| |||.|. ..|.||..... ||. CGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MarkmD3.AA | CAMKL | 14-263 | 32 | 6e-117 | 374.8 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-297/297 Sequence Identity: 32% (97 aa) FRMLLSLGCGSFGEVKLACH-LPTRIRVAVKVLEKNINSMADITS----------------KVELLQSLE---HRNIVRFFHMIDTLTT------TYVIM .|.. ||.||||.||||.| . |...||.|...|. .. .... ......| | ||......|.| .. | .| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYVPGED--LEKYLRALGC----LKEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAAR--NAKLSDFGMAIKTTE-----GQMLEETCDSLLYR ||..| . | |... |. ..|.||| |.|.||||... ...|.|| ||.||||.| |.|..|||.... .. ||.|.. | |. | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEILAR--KPYDGLAVDMWSLGIVLYVLVTGHFPYVEATI--------EYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL ||||... ||||| .||.||.|..||..|.|..| ..|. .....|... . |..|.| .|. .| ..|.| ..|.||||... ||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MarkmD3.AA | CAMK | 19-263 | 21 | 2.4e-92 | 297.82 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 19-263
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)
SLGCGSFGEVKLACHLPTR------------IRVAVKVLEKN-----------------------------INSMADITSKVELLQS-------LEHRNI
|| ||||.|||..| | .||.|...|. .... . . .|.... | |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VRFFHMID------------TLTT--------TYVIM---EYVPGE----DLEKYLRALGC---------------LKEEEARPVFQQVVSAVYFLQQRH
........ | .. | .| ||..| || |... || ..|.||| .|.|..||| .. ...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IAHRNIKLENILVDAA-----------------RNAKLSDFGMAIKTTE------------------------GQMLEETCDSLLYRA-PEILAR-----
|.|| .|.||||.| | |..|||.|.| .. ||.... | .. | | ||.| .
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------KPYDGLAVDMWSLGIVLYVLVTGHFPYVEA-------------TIEYMHRIITTTMCHSIPKHLSI-----------------------PCH
|||.| ..||||.|..||....|..|. . ... ... |.. .. .|...|. |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
IIIARLLMVPTWYRMTIHQLVEQPWL
| ..| | . ||||.| . ||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MarkmD3.AA | AMPK | 14-263 | 33 | 1.4e-70 | 208.73 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-254/254 Sequence Identity: 33% (85 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEKNINSMADITSKVE----LLQSLEHRNIVRFFHMI-DTLTTTYVIMEYVPGEDLEKYLRALGCLKEE . . .|.|.|| ||.. | |. ||.|.|.| | ... .|... | .|.. . | .| | ...||||.| .| | | |.|. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER EARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMAIKTTEGQMLEETCDSLLYRAPEILARKPYDGLAVDMWSLGIVLYVLVTGHFPY ||. .|||..|.| . . |.|| |.||.| |. | |. ||| ..|..| | | | |||. . |.| |. || || |..||... | | EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF VEATIEYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL . . . |. .|||.|| .. .| ..| | |.|||.... ||. DDENTPTLYKKIKNGE-YYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MarkmD3.AA | S_TKc | 14-263 | 26 | 4e-69 | 236.88 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-231/231 Sequence Identity: 26% (69 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEKNINSMADITSKVELLQSLEHRNIVRFFHMIDTLTTTYVIMEYVPG--EDLEKYLRALGC------L ...| .| |.||.|... | | .||.|.. .| . ...|.. | |||... .... . |..|||..| || .|.. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF KEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMAIKTTEGQMLEETCDSLLYRAPEILARKPYDGLAVDMWSLGIVLYVLVTGH | .|| ...|...|. .. ...| || .| ||||.| . |..|||.| . | .. |.|||.| .|.. ..|.||.|..|| ...| PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY FPYVEATIEYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVE-------QPWL |. ... | ..| | .. .| ..| . |.|. .. . ||. PPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MarkmD3.AA | NuaK | 14-263 | 34 | 5.8e-63 | 164.13 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 14-263
Range on HMM: 1-252/252
Sequence Identity: 34% (88 aa)
FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEKN-INSMAD---ITSKVELLQSLEHRNIVRFFHMIDTLTTTYVIMEYVPGEDLEKYLRALGCLKEEE
.... || | .| |||| | ||.| |. | . .| | .|.. ||.| .|. . ..||| | .| |. . | |.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE
ARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMAIKTTEGQMLEETCDSLLYRAPEILARKPYDGLAVDMWSLGIVLYVLVTGHFPYV
|| .| |.||||.. . |.|| |||||| |. ||| |||. ....|. | | || ||| .|| | || ||||..||..| | |.
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD
EATIEYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL
. . |. |.. | | | .||| .| || . . .|.
GHDFKHLVKQISQGAYYE-PCKPSDAC-MLIRWMLMVNPRRRATIYDICHHWWV
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| Kinase | MarkmD3.AA | MELK | 14-263 | 34 | 6.4e-58 | 196.41 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-254/254 Sequence Identity: 34% (88 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEKNI--NSMADITSKVELLQSLEHRNIVRFFHMIDTLTTTYVIMEYVPGEDLEKYLRALGCLKEEEAR . . .| | |. ||||||. | .||.|...|| . . . .. |..|.|..| ...|.|.| ...||| || .. |. |.|||.| YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETR PVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMAIKTTEGQM----LEETCDSLLYRAPEILARKPYDGLAVDMWSLGIVLYVLVTGHFP .|.|.|||. .. . |||..| ||.|.| . || |||. || |.. |. | |. | |||.. | | | |.||.||.||||. | | HFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLP YVEATIEYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL . . .. | . | |. ||.|| .. ..| | |. ...|.. ||. FDDDNMMIMYKKIMSG-CYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV |
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| Kinase | MarkmD3.AA | Pkinase | 14-263 | 26 | 1.8e-54 | 192.08 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-293/293 Sequence Identity: 26% (79 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEK-NINSMADIT----SKVELLQSLEHRNIVRFFHMIDTLTTTYVIMEYVPGE----DLEKYLR--AL .. . .| ||||.|....| |...||||...| ...| |.| | ......| | ||||.... . . |..|||..| || |.. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GCL--KEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNA----KLSDFGMAIK--TTEGQMLEETCDSLLYRAPEILARKPYDGLAVDMWSL ||. |.|.. .. |........ .. | || .|.||||.| . |..||| | . . .. . | .. |.|||.. .|.| .|||||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GIVLYVLVTGHFPYVEA----TIEYMHRIITTTMC----HSIPKHLS-------------------IPCHIIIARLLMVPTWYRMTIHQLVEQPWL |..|| ...|..|. .. . . .| .|. ..|. | .| .| ..| . | |..|... ||. GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MarkmD3.AA | QIK | 14-263 | 32 | 4.7e-53 | 182.57 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 14-263
Range on HMM: 1-272/272
Sequence Identity: 32% (88 aa)
FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEK---NINSMADITSKVELLQSLEHRNIVRFFHMIDTLTTTYVIMEYVPGEDLEKYLRALGC------
. . .| | |. |||| | | .||.|.. | . . . |... .|.| .|.. . . | |...|| .. .. || . |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV
--------------LKEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMAIKTTEGQMLEETCDSLLYRAPEILARKPYDGLAVD
..|.||| .|.|..|||... .|.|.|| .| |||| |. | |. |||. ..||.|. | | | |||.. | ||| ||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD
MWSLGIVLYVLVTGHFPYVEATI-EYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL
||.|.||||||.| .|. |. . .|.. || .| | .| . | | |.|| | .. .|.
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFR--IPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MarkmD3.AA | Ciliate-E2 | 14-263 | 19 | 3.3e-52 | 177.52 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 14-263
Range on HMM: 1-365/365
Sequence Identity: 19% (73 aa)
FRMLLSLGCGSFGEVKLACHLPTRIR-----------------------VAVKVLEKN----INSMADITSKVE----------LLQSLEHRNIVRFFHM
. . .| |.|| |..... .. . .|.|...|| |... .| ... .|..| | ||....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
ID--TLTTTYVIMEYVPGEDLEKYLR------------ALGCLKEEEARPVFQQVVS---------------AVYFLQQRH-IAHRNIKLENILVDAARN
. .. | .|||. | ||..|.. . ....|.|.. ...|... |. .| ... | ||.||.||||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----
AKLSDFGMA-----------------IKTTEG----------------QMLEETCDSLLYRAPEILARKPYDG--------LAVDMWSLGIVLYVLVTGH
|..|||.. ... . .| .| .. | ||||| .|.||. ..|.||||..|| ...|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK
FPYVEATIEYMHRIITTTMCH-S----------------IPKHLSIPCHIIIAR----LLMVPTWYRMT-IHQLVEQPWL
.|. ..| . . ..|..| | .| . .| . |.| . |. . ||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | MarkmD3.AA | SNRK | 14-263 | 36 | 1.2e-51 | 167.23 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-254/254 Sequence Identity: 36% (94 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEK---NINSMADITSKVELLQSLEHRNIVRFFHMIDTLTTTYVIMEYVPGEDLEKY-LRALGCLKEEE . . || | | |||| |. | .|||||..| | | . | .. | |||| . .||| | |.|.| | |. | .. |.|. YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCEDL ARPVFQQVVSAVYFLQQRHIAHRNIKLEN-ILVDAARNAKLSDFGMAIKTTEGQMLEETCDSLLYRAPEILARKPYDGLAVDMWSLGIVLYVLVTGHFPY || | |.. |. . |.|. || .| || . . || ||| . | |. || | || | ||||| || |||.||||..||.|| |. |. ARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPF VEAT-IEYMHRIITTTMCHSIPKHLSIPCHIIIARLLMVPTWYRMTIHQLVEQPWL || | . .|. ...|.|.| |. .|...|. | .. ..|...|. QEANDSETLTMIM--DCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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| Kinase | MarkmD3.AA | Ciliate-E2-Unclassified | 14-263 | 21 | 5.2e-51 | 175.18 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 14-263 Range on HMM: 1-352/352 Sequence Identity: 21% (75 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEKNINSM-------------ADITSKVE-------------LLQSLEHRNIVRFFHMIDTLTTTYVIM .... .| |.||.|... | . | | . |... . ... . . .|... | .||..|.. . . | .| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EYVPGEDLEKYLRAL-----------------GCLKEEEAR-----PVFQQVVSAV-YFLQQRHIAHRNIKLENILVDAAR---NAKLSDFGMAI----- ||..| ||..|.. .. |..|. | |.... | .. .| ||.||.||||.| . |..||| .. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN ---KTTEG---------QMLEETCDSLLYR----APEILARKPYDG---LAVDMWSLGIVLYVLVTGHFPYVEATIEY----------------MHRII- . |.. ||. .| .. | |||.| .. ||. ..|.||||..|| ...| .|. . | ....| NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK ---TTTMCHS---IPKHLSIPCHIIIA----RLLMVPTWYRMTIHQLVEQPWL . ... ||||.| . .| ..| . .|.|. |. . ||. QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | MarkmD3.AA | Pkinase_Tyr | 14-155 | 27 | 4.4e-15 | 51.71 | Pfam | 1-158 (270) | Show / Hide |
Range on Protein: 14-155
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)
FRMLLSLGCGSFGEVKLACHL----PTRIRVAVKVLEKNINSM----ADITSKVELLQSL-EHRNIVRFFHMID-TLTT--TYVIMEYVPGEDLEKYLRA
... || |.||||... |.| ||||.| . . .| . .... .| | ||||. . |..|||.|. || .|||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
----LGCLKEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMA
. |. .. .|. .. .| .... || . |.||. . .| .|||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
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| Kinase | MarkmD3.AA | TyrKc | 14-258 | 21 | 1.2e-14 | 14.06 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-280/280 Sequence Identity: 21% (61 aa) FRMLLSLGCGSFGEVKLACHLPTRIRVAVKVLEKNINSMADITSKVELLQSL--EHRNIVRFFHMIDTL-------TTTYVIMEYVPGEDLEKYLRALGC ... ||.| |||| .. | ||||.| .. ..|. . ... .| .| ||||.. . . ...|||.|. || .|||. . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LKEEEARPVFQQVVSAVYFLQQRHIAHRNIKLENILVDAARNAKLSDFGMAIKTTEG-------QMLEE----TCDS-LLYR--APEILARKPYDGLAV |. .. |. . .| .... || . |.||.. . .| ||||.. . ... .. ... | .| ||| . . . . KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS DMWSLGIVLY-VLVTGHFPYVE-----ATIEYMHRIITTTMCHSIPKHLSIP-----CHIIIARLLMVPTWYR--------MTIHQLV | || |.... .. | || . . . ... . . . .|.. | |. . . .| | . .||.. DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF |
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| UBA_CAMKL | MarkmD3.AA | UBA_CAMKL | 279-316 | 30 | 7e-05 | 15.9 | In-house | 2-41 (41) | Show / Hide |
Range on Protein: 279-316 Range on HMM: 2-41/41 Sequence Identity: 30% (12 aa) PRIVNTMCTI--GYSCEEIVSSLTHRRLKDEVMATFNILK ..|.. ||.. |.. |||..|| .. ....|| .| EEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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