Gene MOK (Mouse)

MOK

Species: Mouse
Alias: MOK, Rage
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP ,
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MOK

Sequence

Name Sequence Type Origin Length Description Download
MOK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 282 Kinase domain by global Sugen HMM Fasta, JSON
MOK.NA RNA Sugen 1698 None Fasta, JSON
MOK.AA Protein Sugen 420 None Fasta, JSON

Protein domain

Protein domains of MOK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MOK.AA MOK 4-285 86 1.8e-253 803.73 In-house 1-283 (283) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-283/283
Sequence Identity: 86% (245 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEK
|||||||||||||||||||||||||||||||||||||||||||.||||||.||||||||||.|||||||||.|.|||||||||||||||||||||.|..|
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

KIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFP
|||.||||||||||||||||||||||||||||.|||.|||.|||||||||||||||||||||||||||||||||.|||.||.||.||||||||||.||||
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLFP

GVNELDQISKIHDVIGTPCQKTLTKFK-QSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF
||||.|||||||||.||||||.|.||| |||||..||||||||||..||.||..|||...|.|..|||||||.|||..|||||
GVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase MOK.AA RCK 4-285 46 2.6e-202 648.14 In-house 1-298 (298) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-298/298
Sequence Identity: 46% (140 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIRG---RRHPL
|..| ..|.||...|||.|....|...|.|.|||.|.|.|....||||..||.|||||||. |.||..|.....|....|.||||.|.....   ||..|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

SEKK--IMLYMYQLCKSLDHMHRNGIFHRDVKPENILVK----------QDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSA
.|..  |. .|||....|.|||..|.||||.|||||...          ||..|..|||.||...||.|||.|.||||||||||||....|...||.|. 
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAV

GCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFK-QSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF
||..||. .|.||||| .|.||| ||..|.|||..|...... ....| |.||..||.... |. |.|..|..|.. |...||..||.|.||||||||
GCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase MOK.AA CMGC 4-285 23 1.2e-113 374.96 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-513/513
Sequence Identity: 23% (120 aa)

YKAIGKIGEGTFSEVMKMQS--------------LRDGNYYACKQMKQHFESIEQV----------NSLREIQALRRLN----------------PHPNI
|. |.||||||...| | .                ......| | .|. |. ...            .||||. |..||                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

LALHEVVFDRKSG---------------SLALICELMDMNIYELIRG--------RRHPLSEKK------------IMLYM------YQLCKSLD--HMH
. |.... ...|                .| |. |.||.. |..|.         |..|||| .            |  .|      ||....|.  ..|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

RNG--IFHRDVKPENILVKQD---------------------VLKLGDFGSCRSVYSK----------------------QPYTEYISTRWYRAPECLLT
...  |.||| ||||||. ..                     .||..|||..|.. .                       .|||.|..|||||||| || 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

DGFYT---------YKMDLWSAGCVFYEIAS--------LQPLFPGVNE-----------LDQISKIHDVIGTPC---------------QK--------
.. ||         ...| ||.||.|.|.          ..||||| .|           .||. || .|.|||.               ..        
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

------------------TLTKFKQSRAMSFDFPFKKGSGIPLLTAN-----------------------------------LSPQCLSLLHAMVAYDPD
                     . .. . . ..|| ...  .  |  .                                   ..||.. ||  |  ||||
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

ERIAAHQALQHPYF
.|| | ||||||||
KRITAEQALQHPYF
Kinase MOK.AA MAK 4-285 32 7.7e-93 295.86 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-352/352
Sequence Identity: 32% (113 aa)

YKAIGKIGEGTFSEVMKMQS------------------------------LRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNILALHEVVFDR
|  | ..| ||. .||. ..                                 |   | |.||. | | |   .|||. .|. || ||||  | ||. | 
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

KSGSLALICELMDMNIYELIRGRRH-PLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQ------------------DVLKLGDFGSCRSVYS
    | .. | |  | |... .|.   ..|  |   |||    | .||..| |||| |||||..                    ...|. |||  | . |
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRS

KQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKT-----------------LTKFKQSRAMSF
| ||| |.||||||||| ||  . |   .|.|  ||.  |. .. ||||| .| ||| ||  |.|||  ..                    .. . .| |
KPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNF

DFPFKKG---SGIPLLTANLSP-QCLSLLHAMVAYDPDERIAAHQALQHPYF
 ||   .   . .  |  | |.   . |.  | ..||..|  | |....|||
RFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase MOK.AA S_TKc 4-285 29 4.2e-87 296.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-231/231
Sequence Identity: 29% (88 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDM---NIYELIRGRRHP-
|. . |||.|.|..|.| .  ..| ..|.|..|         . .|||| |..   ||||  |..|  |   ..| .. |..|    . ...|. |... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTY-KMDLWSAGCVFYE
    ..|  .  ||||.|. |...|..|| |||.||||||. . ..|..|||..| .      | .. |.||.||| |     |.. | | || ||..||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

IASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQ-------HPYF
 .. .|.||      |. .. ..||                                   ||......  .  .||..|. | .|||       ||.|
MLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MOK.AA CDK 4-285 31 6.3e-84 268.37 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-284/284
Sequence Identity: 31% (100 aa)

YKAIGKIGEGTFSEVMKMQSLRDG-----NYYACKQMK-QH-----FESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSG---------SLALICE
|. . ||||||. .| | .....|     ...| |. . ..      .      ..|||  |. |  ||||  ||.|. . ..          .| .. |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMDMNIYELIRGRRHPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVK-QDV-----LKLGDFGSCRSVYS-------KQPYTEYISTRWYRAP
 ||.  .....          |  ||.|| . |...|.|.| ||| || |||.  . .     ||..|||  |   .        ..||  . |.|||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ECLLTDGFYT--YKMDLWSAGCVFYEIAS---LQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAM
| || .  |.     |.||.||.|.|..     .||||| .|.||. || ...|||. ..   ...                             ||  |
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKM

VAYDPDERIAAHQALQHPYF
 .|||. || | ||||||||
LCYDPKKRISAEQALQHPYF
Kinase MOK.AA CDC2 4-285 33 1.8e-80 246.94 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-301/301
Sequence Identity: 33% (103 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQ---VNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIR---GRR
|. | ||||||. .| | . .... . | |. .   |. .      ..|||  |  |..||||  ||.|..     .| .. | .||.  .. .   . .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

HPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQD-VLKLGDFGSCRSV-YSKQPYT--EYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFY
 .... ..  ||||... ... |...|.||| || |||.  . ..|..|||  | . . . .||    . |.|||||| || . .|.   |.|| ||.|.
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EI---ASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTAN---------LSPQCLSLLHAMVAYDPDERIAAHQALQ
|.   ..  |||.|  | ||. ||  ..|||  .|.   .|      .||  | ...  .  |         | |....||  | .|||  || | .|||
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HPYF
||||
HPYF
Kinase MOK.AA Pkinase 4-285 29 6.8e-76 263.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLR---EIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDM-----NIYELIR-
|. ..|||.|.|..| | .   .|  .|.|..| . |. ..  ..|   ||| ..||| ||||. |.... |  .... .. |....       ...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

GRRHPL--SEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVK-QDVL----KLGDFGSCRS--VYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDL
 |. ..  ||. .  ||||... |...|..|| |||.||||||.. ....    |..|||...     ... .| .  |.||.||| ....  |..| | 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSAGCVFYEIASLQPLFPGV----NELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQ
||.||..|| .. .|.|||     | .||. .|  . |.|      .    .  . ... .      ..  |.|. |....  . ..|| .|. |.|.||
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPYF
||.|
HPWF
Kinase MOK.AA CDK5 4-285 33 3.6e-63 198.25 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-287/287
Sequence Identity: 33% (99 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESI-EQVNS--LREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHPL
|. . ||||||.  | | .    . ..| |. .   .|  | | |  .|||  |. |  |.||  || |.   |   | |. | .|  .   .  .   .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVR--LDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNGEM

SEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILV-KQDVLKLGDFGSCRSV-YSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIA-S
. . |  .|||| | |   | . . ||| || | |. |.  |||.|||  |      . |.  . | |||.|  |.    |.   |.||.||.| |.| .
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

LQPLFPGVNELDQISKIHDVIGTPCQKT---LTKFKQSRAMSFDFPFKKGSG-IPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF
..||||| .. ||  .| ...||||  .   .||  . ..   ..|   .      .. .|. . . ||. |  ..|..|| | .||.||||
GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase MOK.AA MAPK 4-285 31 6.9e-57 195.22 In-house 1-328 (328) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-328/328
Sequence Identity: 31% (103 aa)

YKAIGKIGEGTFSEVMKMQSLR------DGNYYACKQMKQHFESIEQVN-SLREIQALRRLNPHPNILALHEVVFDR-----KS----GSLALICELMDM
|. . .||.| .  | .    |      .|.. | | . . |..       .|||  ||... |.||  | ..         .|      . .. |||. 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NIYELIRGRRHPLSEKKIMLYMYQLCKS--LDHMHRNGIFHRDVKPENILVKQD-VLKLGDFGSCRSVYSKQPY---------------TEYISTRWYRA
. . .|. .. |||.. |   |||...   | ..|  .. ||| ||.|||| ..  ||..|||  ||. ... .               |||..||||||
DLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PECLLTD--GFYTYKMDLWSAGCVFYEIAS-LQPLFPGVNELDQISKIHDVIGTPCQKTLTKFK-QSRA----MSFD-FPFKKGSGIPLLTAN----LSP
|| .|      || ..| ||.|| | |  .  .||||| . .||. .| .|.||| .  . . .  ..|     |.  .| ...     .  |     .|
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANP

QCLSLLHAMVAYDPDERIAAHQALQHPYF
|.. ||  | . |||.|| . .|||||||
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase MOK.AA Ciliate-E2 4-285 20 1e-55 189.73 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-365/365
Sequence Identity: 20% (81 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYA----------------CKQMKQHFESI--EQVNSL-REIQALRRLNP---------------HPNILALHEV
|| | |||.|.|. | |..  .... .|                .|...   ...   |.... .||. .|..|.               ||||. ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VFDRKSGSLALICELMDM-NIYELIRGRRH----------PLSEKKIMLYMYQLCK---------------SLDHMHRNG-IFHRDVKPENILVKQDVLK
  . .  .. |. |. .  . ...|. ...          ...||.|  .|.|...                | ..| .. |.||| ||||||.    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

LGDFGSCRSVYSK----------QPYTEYIS-----------------------TRWYRAPECLLTDGF--------YTYKMDLWSAGCVFYEIASLQPL
. ||| .. .  .          . |..  .                       |  | ||| |   .         |.|| |.||.|...||  . .| 
IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLL--------TANLSPQCLSLLHA----MVAYDPDERIA-AHQALQHPYF
|                          ..|     .|||...     ..        . ..|..|  |.      |  .||..||  . |.|.||.|
F--------------------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MOK.AA CDKL 4-220 36 3.1e-54 183.8 In-house 1-218 (286) Show / Hide 
Range on Protein: 4-220
Range on HMM: 1-218/286
Sequence Identity: 36% (80 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQ-HFESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSE
|  .||.|||    |||      | . | |  |    . ..  . .|||  |. |  |.||  | ||   |. . | |  | .| .. ..   . . . |
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLK-HENIVNLIEVF--RRKRKLHLVFEYCDHTVLHELEEYPNGVDE

KKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVK--QDVLKLGDFGSCRSVYSKQP--YTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASL
.... ||.|..|.... | . . |||.||||||.   ....||.|||  |   .|.   ||.|  |||||||| |. |  |    |.|..|||. | .. 
HVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDG

QPLFPGVNELDQISKIHDVIGT
|||.|| ...||  .|  ..|.
QPLWPGQSDIDQLYHIQKCLGP
Kinase MOK.AA TyrKc 4-285 21 5.8e-13 -13.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-285
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRL-NPHPNILALHEVVFDR-----KSGSLALICELMDM-NIYELIRGR
 . . |.||| | ||.| .        | | .| .   .|    .||.. ...|   ||||..|. |. .       .. | .. |.|.  .  . .| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDF--MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RHPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDV-LKLGDFGSCRSVYSK-------QPYT------EY--ISTRWYRAPECLLTDGFYT
|. |. |.   ...| ..  .. |.... |||    |.||. .   | .||| .| .|..       . |.      .   .  ||. ||||.  .| .|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKFT

YKMDLWSAGCVFYEIASL-QPLFPGV----NELDQISKIHDVIGTPCQKTL----TKFKQSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMV----A
 | | || | . .|| .. |.  ||.     . ... .  .  . . |                                   .. | . .. .     .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------FVCCPDEMYQIMKQCWH

YDPDERIAAHQALQHPYF
.||..|    .   | .|
EDPEDRPTFSEI--HECF
Kinase MOK.AA Pkinase_Tyr 4-198 26 3.7e-12 41.8 Pfam 1-210 (270) Show / Hide 
Range on Protein: 4-198
Range on HMM: 1-210/270
Sequence Identity: 26% (57 aa)

YKAIGKIGEGTFSEVMKMQSLRDGNYY----------ACKQMKQHFESIE--QVNSLREIQALRRLNPHPNILALHEVVFDRKSG-SLALICELMDM-NI
 . . |.||| | ||.|      | ..          | | .|..  . .  .   .||.. .. |  ||||. |. |. |..   .. .. |.|   . 
ITFGKKLGEGAFGEVYK------GTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

YELIRGR---RHPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVK-QDVLKLGDFGSCRSVYSKQPY-----TEYISTRWYRAPECLLTDGFYT
..  | .   ..||. | .  . .| .| ... ..... |||.   |.||. . | | .||| .| .|..  |        .  .|. ||||. .   .|
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FT

YKMDLWSAGCVFYEIASL
 | | || | . .|| ..
TKSDVWSFGVLMWEIFTY
Kinase MOK.AA CDKL 253-285 38 1.6e-10 32.22 In-house 253-286 (286) Show / Hide 
Range on Protein: 253-285
Range on HMM: 253-286/286
Sequence Identity: 38% (13 aa)

NLS-PQCLSLLHAMVAYDPDERIAAHQALQHPYF
|.| .  |......   |||||. . |...||||
NKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF