Gene MYO3A (Mouse)

MYO3A

Species: Mouse
Alias: MYO3A, Myo3a
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: NinaC

Sequence

Name Sequence Type Origin Length Description Download
MYO3A.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
MYO3A.AA Protein Sugen 1621 None Fasta, JSON
MYO3A.NA RNA Sugen 5082 None Fasta, JSON

Protein domain

Protein domains of MYO3A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MYO3A.AA NinaC 29-295 77 1.1e-227 762.75 In-house 1-267 (267) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-267/267
Sequence Identity: 77% (208 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLKRGE
|||.||||||||||||||.||..||.|||||...|||.||||||||||||...||||||||||.|.||||.|||.||.|.|.||||||||.|||.||.|.
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

RMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITA
||.|..||||||||.|||||||.|..||||||||||||||||||||.||||||||.|||||.||.||||.|||||||||.||.|..||||||.|||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
|||||||||.|..|||||.|||||||||.|..||.|..|||||||.||.|||||||.....|.|.||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase MYO3A.AA STE20 29-295 50 3.9e-159 534.96 In-house 1-288 (288) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-288/288
Sequence Identity: 50% (146 aa)

WEIIETIGKGTYGKVFKVLNKKSGQK----AAVKILDPIH-----DIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDL
.|..| ||.|.||||.|. .|..|..    .|.|...  .     |  |.|. |..|.. .  |||.|..|| |.|.|.  .|.||.| |.|.|||.||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC-DDELWIVMEYCGGGSLTDI

VKGFLKRGE-----RMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSS----TRH-RLNTSVGTPFWMAPEVIACEQ
.|...|.|      .|.|. ||||..|.| ||..||||. ||||.|..|||||..| |||.||||.|||..    |.. . || ||||.|||||||.|..
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

QLDTTYDARCDTWSLGITAIELGDGDPPLAELHPMRALFKIP--RNPPPKLRQ--PELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
. |  || .|| |||||||||. .| ||....|||||.|.||  .||||.|..  |. || ||.||..|||.||.|||||.|.||||.||
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MYO3A.AA STE 29-295 37 1.6e-131 443.28 In-house 1-359 (359) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-359/359
Sequence Identity: 37% (136 aa)

WEIIETIGKGTYGKVFKVLNK------KSGQK---------AAVKILDPIH------------------DIDEEIEAEYNILRTLSD-HPNVVRFYGIYF
||.|| ||||..|.|.| .|.      |.|..          |.|...  .                  .. ..|. | .|.. ... |||.|..|| ||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KKDKI--NGDKLWLVLELCNGGSVTDLVKGFLKRGE----------RMSEPVIAYILHEALMG-LQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSA
|...   |.|.||...|...|||..|..|   ..|.          |..|..||||... | | |..|||.. ||||.|. ||||     |||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLSS---------------TRH-RLNTSVGTPFWMAPEVIACEQQL-DTTYDARCDTWSLGITAIELGDGDPPLAELHPMRALFKIPRN-----------
||..               |.  . || |||| ||||||| ...|  |  ||..|| ||||.|.||. .| ||....|||||.| ||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPKLRQ-----------------PELWSAEFNDFISKCLTKDYEKRPTVSDLLK--HKFI
    |||.| .                 |. || ||.|||.|||.||..||||.|.|||  |.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MYO3A.AA MSN 29-295 54 5.4e-121 401.37 In-house 1-265 (265) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-265/265
Sequence Identity: 54% (145 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKI-NGDKLWLVLELCNGGSVTDLVKGFLKRG
.|..|..|.||||.|.| . .| || ||.|..|  .| .|||  | |.|.  | | |.. .|| ..||    . ..||.|.|.|  ||||||||    .|
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVK--MTKG

ERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGIT
. . |  ||||  | | ||.|||..| ||||.|| |.||| .  ||||||||||||. |  | || .|||.|||||||||. . |.||| | | ||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
|||. .|.||| ..||||||| |||||||||.  . ||  |..|. ||| |.|..||.  ..||| ||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase MYO3A.AA MST 29-295 46 5.6e-116 370.16 In-house 1-254 (254) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-254/254
Sequence Identity: 46% (126 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDID-EEIEAEYNILRTLSDHPNVVRFYGIYF-KKDKINGDKLWLVLELCNGGSVTDLVKGFLKR
 .|.| .| | ||.|.| ..|..|.  |.|.. |. . | .||. | .|.    . ...|..|| ||  |..     .|.| | |..||| |..|    .
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMV-PV-NEDLQEIIKEISIMQQC-KSKYIVKYYGSYFDAKNN----HCWIVMEYCGMGSVCDIMK---IT

GERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI
.   .|  || ||  .| ||| ||.|| |||| |  |||| .||  || |||||.||. |    || .|||.|||||||         ||   | |||||
QRTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLGI

TAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
||||.  | ||....|||||.|.|| .|||... || || |||||..|||.|. |.|.|  .||.| ||
TAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase MYO3A.AA YSK 29-295 44 1.8e-111 336.97 In-house 1-257 (257) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-257/257
Sequence Identity: 44% (121 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDID--EEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKG-FLK
. . | ||.| .| |.|  ... ..  |.||.|  |. |  | |  | ..|  . | |.. ..|| | |     . ||| . | | |||. || |  .. 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQC-DSPYITKYYGSYLK-----DTKLWIIMEYCGGGSCLDLMKPKYV-

RGERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLG
    . |. || ||.| | ||  |||.. ||||.|  |.||. .| ||| ||||..|.  |  ..|| ||||.||||||| .|    . ||.  | ||||
--GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEV---SYYDFKADIWSLG

ITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
|||.|.  | ||....||||..| || |.||||   . .|  | .|.  || || |.||. ..|||||||
ITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase MYO3A.AA S_TKc 29-295 34 9.7e-94 318.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNG--GSVTDLVKGFLKR
.||...||||..|||.|. .||.|.. |.||..      | |. | .||.   .|||.|..|...        |.|..|.|.|.|  |.. |. |   ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

GER--MSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDA-RCDTWS
| |  ..| ........ . .|...||.. ||||.|  ||||..   .|. |||...||       .| .|||..|||||.         |.  .|| ||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWWS

LGITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLK-------HKFI
.|.. .|.  | ||      | ..||. .            | |. |||.|||.|| |||||. ..|.       | ..
CGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MYO3A.AA SLK 29-295 42 2.4e-90 304.98 In-house 1-259 (259) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-259/259
Sequence Identity: 42% (113 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDID-EEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLKRG
||||  .| | .||| |  .|  .. || |...  .. . |.   | .|| ..  |||.|. |. |.       .|||...| |.|| |  ..   .  .
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYYYD-----NKLWMMIEFCDGGAVDNIM---VELE

ERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGIT
. . |. |.|. .. . .|..||||| ||||.|  |||.| .|.|.| ||||||.. .|...  | .|||.||||||..||   |. || . | ||||||
HPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGIT

AIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
 ||. ...||  |. ||| |.|| .  ||.| ||  || ||.||. ||| || ..|.| ..|..|...
LIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase MYO3A.AA KHS 29-295 43 1.8e-87 294.26 In-house 1-258 (258) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-258/258
Sequence Identity: 43% (118 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKI--LDPIHDIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLKR
.|..  .| |||| |.|  ...|.. ||||.  ..|  |. . |  |  .... . |||.| ..| |...     ||||...| | |||. |.     . 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDF-AVIQQEIMMMKDCR-HPNIVAYFGSYLRR-----DKLWICMEYCGGGSLQDI----YHV

GERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI
   .||  |||. .|.| ||..|||.. .|||.|| ||||| .| ||| |||||||.. |  .    .|||.|||||| | |..    |.  || |..||
TGPLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK--GGYNQLCDIWAVGI

TAIELGDGDPPLAELHPMRALFKIPRNP--PPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
|||||..  ||. .|||||||| . .    ||||.. . ||. | .|.  .|||.  |||| . ||.|.|.
TAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase MYO3A.AA PAKL 29-295 40 3.2e-82 279.48 In-house 1-256 (256) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-256/256
Sequence Identity: 40% (110 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDI-D-EEIEAEYNILRTLSDHPNVVRFYGIYFKK-DKINGDKLWLVLELCNGGSVTDLVKGFLK
 |. |  | | || |.|.. | ..   |.| . .|    . ..|| | .||      ||.|  .|    | .     ..|  .. |  ||. |. .   |
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVI-EIKESNEIKDIEKEIQILKK-CKCPNIVSYFGSIQQKLN-----HYWILMDYCSLGSINDMMESCCK

RGERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRH-RLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSL
    . |  |. ||  .| ||  |||   ||||.|  ||||.  . ||. ||||| || ..     |  .|||.|||||.|     . . |.  || |||
---TLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEII-----NKQNYNNKCDIWSL

GITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
||||||. || ||. .. ||||.  ||. |||..  |  || .||||. .|..|| |||. ..||| | ||
GITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase MYO3A.AA PAKA 29-295 39 8.3e-82 278.09 In-house 1-260 (260) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-260/260
Sequence Identity: 39% (106 aa)

WEIIETIGKGTYGKVFKVLNKKSGQK--AAVKILD-PIHDIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLK
 . .| ||.|  |.|... |.| .|.   |.| ..    .  | |  |  .... . |.|.|...  |    ..  |.||.|.|  .||. ||... . .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKE-CKHKNIVNYIDSY----LV-DDELWVVMEYMEGGCLTDVITQCCN

RGER-MSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSL
     |.|  |||.. | | ||. .||.. ||||.|  |||| ..| ||. |||  |||.  . . || |||| |||||||   |     ||   | |||
IQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDIWSL

GITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
|| |||. .| ||  .  | ||.. |  |  |....|. || ||.|| .||| .| ..|.....||.| |.
GIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MYO3A.AA Pkinase 29-295 29 1.9e-79 275.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-293/293
Sequence Identity: 29% (90 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDIDEEIEA-----EYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGG----SVTDL
..|...||.|..|.|.|  .|..|.. ||||..  |. ... ..     |  |.. | .|||.||.|...       .|....|.|.|.||    .  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

VKGFLKRGERM--SEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGV----KLVDFGVSAQL-SSTRHRLNTSVGTPFWMAPEVIACEQQLD
...  .|. ..  || ..  .. . | ||...||.. ||||.|  |||.  .| .    |. |||...|.     . ..| .|||..||||||      .
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GG

TTYDARCDTWSLGITAIELGDGDPPLAEL----HPMRALFKIPRNPPPKLRQPELWS---------------------AEFNDFISKCLTKDYEKRPTVS
. |. ..| ||.|.. .|.  | ||  .     . .. ...| |. .|.|. .. |.                      |. |||..||.|| .||||  
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

DLLKHKFI
..|.|...
QILQHPWF
Kinase MYO3A.AA Pkinase_Tyr 29-295 24 5e-28 95.54 Pfam 1-270 (270) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-270/270
Sequence Identity: 24% (70 aa)

WEIIETIGKGTYGKVFKVLNK----KSGQKAAVKILDPIHDID----EEIEAEYNILRTLSDHPNVVRFYGIYF-KKDKINGDKLWLVLELCNGGSVTDL
 ......|.| .|.|.|   |    . ... |||.| . .. .    |.  .| .|...| .|||.||.||.   ... .   ....|.|.. .|   ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHG---DL

VKGFLKR----GERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQL-----SSTRHRLNTSVGTPFWMAPEVIACEQQ
 . .|..    ... . . .  . ..  .|...|.|.. ||||.   |.|.| .. ||  ||| .  .       .| | ..     .|||||.|.    
LD-YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGK-

LDTTYDARCDTWSLGITAIELGD-GDPP-LAELHPMRALFKI-PRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
    .    | || |..  |.   |. |  ... . . . .|  ..    . .||. ..|  | . .|  .| |.||| |..  | ..
----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase MYO3A.AA TyrKc 29-295 22 7.2e-17 50.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 29-295
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

WEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDIDEEIEAEYNILRTL-SDHPNVVRFYGIYFKKDKING---DKLWLVLELCNGGSVTDLVKGFL
 . ....| | .|.|.|   |   .. ||| | . .   |..  | .|.. |  .|||.||.||.  ..        . |..|.|.. .|.     | .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGD----LKDYL

KRGER-MSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSST-----RHRLNTS---VGTP-----FWMAPEVIACEQQ
.. ..  . .   .. . .  | ..|||.. ||||    |.|.. .. ||  ||| |  . .      ..   ..    |.       |||||.|     
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

LDTTYDARCDTWSLGITAIEL-GDGDPPLAE-----LHPMRALFKIPRNPPPKLRQPEL--------WSAEFNDFISKCLTKDYEKRPTVSDLLKHKFI
 . ..    | || |..  |.  .|..|  .     . . ... .. .     ..||.          ..|  . ...|   | |.||| |..  |...
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
MYSc MYO3A.AA MYSc 340-1061 33 8.99999999999e-255 853.58 SMART 1-771 (771) Show / Hide 
Range on Protein: 340-1061
Range on HMM: 1-771/771
Sequence Identity: 33% (273 aa)

SLISSLKDVDDLATLDVLDENTVSEHLEKCYSRDQIYIYVGDILIALNPFQSL-GIYSTKLSRLYI------GAKRTANPPHIFAMADLGYQSMVTYNAD
     ...|||...|. | | .| ..|.| | .|||| | |...||.||.. | .||.    ..|       | .|  .|||||| ||  |..| ... .
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN

QCIVISGESGAGKTESAHLLVQQLTVLGKANNRTLQEKILQMNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEK
|||.|||||||||||..... | |. ..  . ......||| | . |||||| |. |.|||||||| |. |  .| ..|| |. ||||||||..|. || 
QCIIISGESGAGKTENTKKIMQYLAAVSG-QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGER

NFHIFYYIYAG--LAEKKKLALYK----------LPENK-PPRYLQNDNLRTV---QDMMNNSFYKSQYEL----IEQCFKVIGFTMEQLGSVYSVLAAI
|.||||...||   ..|... | .          |  .. ....   .        .   .    .  ..     ... ..|.||. |.  ......|||
NYHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNN-K-R----HQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAI

LNVGNIEFSSVAT--EYQMDKSY-ICNHTALENSASLLCIQADELQEALTSHCVVTRGE---TIIRPNTVEKAADVRDAMAKTLYGRLFSWIVNCINSLL
|  |||||.. .   ..|   |  . ....|.| ..|| . ...|...||.  ..|..|   .|..|..|| |.. |||.||..|.|||.|||. ||. .
LHLGNIEFEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM

KHDTSPSGDEELNIGILDIFGFENFKRNSFEQLCINIANEQIQYYFNQHVFAWEQNEYLNEDVDARVIEYE--DNRPLLDMFLQK---PMGLLSLLDEES
           . ||.|||.|||.|..|||||.||| .||. |..||.|.|  || || .| .. . |..   || | .|   .|   |||..||||||.
---------HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEEC

RF---PKATDQTLIEKFEDN-----LKSQYFWRP------------KRMELSFGIHHYAGKVLYSASGFLAKNRDTFPTDIVLLLRSSENSVIRQLVNHP
.|   ||.||||..||   .     .|.  ....            .... .|.|.||||.| |.. |.| ||.|| . |.. |..|| |..|.|| .. 
MFHAQPKGTDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEY

LTKTGNLPLSKT-----------------KNIVNYQMWNSEKSTNLTKGETRDVTCHACETTNVKTQTVSSYFRYSLMDLLSKMVVGQPHFVRCIKPNNE
 ..|.. |. |.                 |                           .| .   . .||.. |. .| .|....   .||..||||||.|
EDQTSQTPQEKSSQGKNKSRRKKRMMQMKK---------------------------TC-MQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEE

RQARKYDKEKVLLQLRCTGILETARIRRLGYSHRILFANFIKRYYILCYKSSEEP---------PVSPDTCAAILEKAG---------LDNWALGKTKVF
......| ..|| |||| |.||. |||| |...|. .. | .||..|| .  . .             . | |||.. |          | ...||||||
KKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPYQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVF

LK-YYHVEQLNLMRKE
.. ..... |  ||..
FRNPGQLFHLEEMRER
Myosin_head MYO3A.AA Myosin_head 348-877 36 8.49999999999e-182 615.05 Pfam 1-586 (765) Show / Hide 
Range on Protein: 348-877
Range on HMM: 1-586/765
Sequence Identity: 36% (215 aa)

VDDLATLDVLDENTVSEHLEKCYS-RDQIYIYVGDILIALNPFQSLGIYSTKLSRLYIGAKRTANPPHIFAMADLGYQSMVTYNADQCIVISGESGAGKT
|.|.. |  | |..| ..|.| |   |.|| |.|...|..||.. | ||. .    | | .|. .|||||| ||  |..|...  .|||.|.||||||||
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLPIYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAGKT

ESAHLLVQQLTVLGKANN----RTLQEKILQMNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAV----VGAQISEYLLEKSRVIHQAIGEKNFHIFY
|.. .. | .. ..  |.    ... ..||| | . |||||| |. |.||||||||.|. |. .| .    ||. |. ||||||||..|. || ||||||
ENTKYVMQYFASVSGSNPGVNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHIFY

YIYAGLAEKKKLALYKLP--ENKPPRYLQNDN---LRTVQDMMNNSFYKSQYELIEQCFKVIGFTMEQLGSVYSVLAAILNVGNIE-FSSVATEYQMDKS
...||... . .. ..|     |  .|| ...     || | ....     .. ... ...|||| |.  |.....||||. ||.. | . . | |    
QLLAGASQQEEKKELHLTSADPKDYHYLNQSGTNPCYTVDDGIDDA---EEFQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA---

YICNHTA-LENSASLLCIQADELQEALTSHCVVTR----GETIIRPNTVEKAADVRDAMAKTLYGRLFSWIVNCINSLLKHDT-----------------
 . .... .|. ..|... . |.. .|..  ..|.     |.. .| ..|.|.. |||.||..|.|.| |||| ||  ..| |                 
VVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAAQWDDTV

---------SPSGDEELNIGILDIFGFENF-KRNSFEQLCINIANEQIQYYFNQHVFAWEQNEYLNEDVDARVIEY-EDNRPLLDMFLQK--PMGLLSLL
            ..  . ||.|||.||| | ..|||||.||| .||. |..||.|.|  || || .|... . |.|  || |  |  . |  |||.||||
SITVVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCD-LIEKKKPMGILSLL

DEESRFPKATDQTLIEKFEDNL--KSQ--YF-WRP-K------RMELSFGIHHYAGKVLYSASGFLAKNRDTFPTDIVLLLRSSEN-SVIRQL
|||..||||||||...|  ..   |.    |  .| .      ... .| |.||||.| |...|.| ||.|. . | . |...| . . ...|
DEECWFPKATDQTFLQKLYQTHSSKHPRLHFAQKPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQEL
Myosin_head MYO3A.AA Myosin_head 931-1048 34 1.7e-37 129.11 Pfam 633-765 (765) Show / Hide 
Range on Protein: 931-1048
Range on HMM: 633-765/765
Sequence Identity: 34% (46 aa)

QTVSSYFRYSLMDLLSKMVVG---QPHFVRCIKPNNERQARKYDKEKVLLQLRCTGILE-TARIRRLGYSHRILFANFIKRYYILCYKS------SEEPP
|||.. |. ..  |.  .       ||.|||||||...|... | . || |||| |.|| . ||.| |...|.... | .||.||| |.      .|  .
QTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWSWIWPEWNG

VSPDTCAAILEKA---GL--DNWALGKTKVFLK
 . . | .||..    ..  . ...||||.|..
DTKQGCEKILQHLSWGNMDKEEYQFGKTKIFFR
IQ MYO3A.AA IQ 1063-1083 28 0.080484 9.77 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1063-1083
Range on HMM: 1-21/21
Sequence Identity: 28% (6 aa)

TNKLVLIQASVRAFLGARRYQ
.   ..||| .|..|  ..|.
HRAAIKIQAWWRGYLARKHYR
IQ MYO3A.AA IQ 1061-1083 30 0.118337 7.82 SMART 1-23 (23) Show / Hide 
Range on Protein: 1061-1083
Range on HMM: 1-23/23
Sequence Identity: 30% (7 aa)

EATNKLVLIQASVRAFLGARRYQ
. .   ..||| .| .|  .||.
RMHRAAIIIQAWWRGYLARKRYK
IQ MYO3A.AA IQ 1090-1110 38 3e-05 20.88 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1090-1110
Range on HMM: 1-21/21
Sequence Identity: 38% (8 aa)

KSSAVIIQSAARRHLLRKHGK
. .|..||.. |..| ||| .
HRAAIKIQAWWRGYLARKHYR
IQ MYO3A.AA IQ 1088-1110 39 5.7e-05 23.77 SMART 1-23 (23) Show / Hide 
Range on Protein: 1088-1110
Range on HMM: 1-23/23
Sequence Identity: 39% (9 aa)

KRKSSAVIIQSAARRHLLRKHGK
.....|.|||...|..| ||. |
RMHRAAIIIQAWWRGYLARKRYK