Gene MYO3B (Mouse)

MYO3B

Species: Mouse
Alias: A430065P19Rik, MYO3B
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: NinaC

Sequence

Name Sequence Type Origin Length Description Download
MYO3B.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
MYO3B.NA RNA Sugen 6256 None Fasta, JSON
MYO3B.AA Protein Sugen 1333 None Fasta, JSON

Protein domain

Protein domains of MYO3B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MYO3B.AA NinaC 43-309 73 3.9e-227 760.85 In-house 1-267 (267) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-267/267
Sequence Identity: 73% (196 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCGK
|||.|||||||||||.||.||..|..||||......|.|||||||||||.....|||||.||||.||.|.|.|.|||.|.|.|||||||..|||||.||.
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

RLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITA
|..|..|.|||..|..|||||||...||||||||||||||||||||.||||||||.|||.||||.||||.|||||||||.||||..||||||||||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
|||||||||...|||....|||||||||||.||..||.|||.||||||.||.||||...|.|.||||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase MYO3B.AA STE20 43-309 48 6.30000000001e-156 524.31 In-house 1-288 (288) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-288/288
Sequence Identity: 48% (140 aa)

WEIIETIGKGTYGKVYKVANKRDGSL----AAVKVLDPVS-----DMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTEL
.|..| ||.|.||||||. .|. | .    .|.|...  .     |. |.|. |..|.. .  |||.||.|| ..| | | . .||.| |.|.|||.|..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC-DDELWIVMEYCGGGSLTDI

VKGLLRCGK-----RLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTS----TRL-RRNTSVGTPFWMAPEVIACEQ
.|. ..|||     ...|. |.||....| ||..|| ..|||||.|..|||||..| |||.||||.||||.    |.  .||| ||||.|||||||.|..
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

QYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIP--RNPPPTLLH--PDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
..|. || .||.|||||||||. .| ||.|.|||....|.||  .|||||| .  |..|  ||..|...|| || ||||....|| ||||
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MYO3B.AA STE 43-309 35 3e-126 425.71 In-house 1-359 (359) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-359/359
Sequence Identity: 35% (129 aa)

WEIIETIGKGTYGKVYKVANKR---------------DGSLAAVKVLDPVS------------------DMDEEIEAEYNILQFLPS-HPNVVKFYGMFY
||.|| ||||..|.||| .|.                 | . |.|...  .                  .  ..|. | .|.. . . |||.||.||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KADRC--VGGQLWLVLELCNGGSVTELVKGLLRCGKRLD----------EAVISYILYGALLG-LQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSA
| ...   ...||...|...|||.....|    |||.|.          | .|.||..  | | |..|| |.|||||.|. ||||     |||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTS---------------TRL-RRNTSVGTPFWMAPEVIACEQQY-DSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRN-----------
|||.               |.  .||| |||| ||||||| ...|  |. ||..||.||||.|.||. .| ||...||| ...| ||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPTLLH-----------------PDSWCEEFNHFISQCLIKDFEKRPSVTHLLD--HPFI
    |||.| .                 |..| .||..||..||.|| .|||... ||   ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MYO3B.AA MSN 43-309 51 3e-113 375.37 In-house 1-265 (265) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-265/265
Sequence Identity: 51% (139 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKAD-RCVGGQLWLVLELCNGGSVTELVKGLLRCG
.|..|..|.||||.|||   .. |.|||.||.|   | .|||  | |.|.    | |.. .|| | |        |||.|.|.|  ||||.|||     |
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVK--MTKG

KRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGIT
. | |  | ||    | ||.||| |..||||.|| |.||| .  ||||||||||||  |  |||| .|||.|||||||||. . | .|| | |.||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
|||. .|.||| .|||.. || |||||||.|     |   |..|. .||||....||.  ..| ||||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase MYO3B.AA MST 43-309 45 1.1e-108 346.61 In-house 1-254 (254) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-254/254
Sequence Identity: 45% (123 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMD-EEIEAEYNILQFLPSHPNVVKFYGMFY--KADRCVGGQLWLVLELCNGGSVTELVKGLLR
 .|.| .| | ||.|||  .| .|.. |.|.. || . | .||. | .|.|   | ...||.|| ..  |       ..|.| | |..|||  ..|    
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMV-PV-NEDLQEIIKEISIMQQCKS-KYIVKYYGSYFDAKNN-----HCWIVMEYCGMGSVCDIMK---I

CGKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLG
 .. | |. |. |||..|.||| ||  ..|||| |  |||| .||  || |||||.||| |   ||| .|||.|||||||       . ||   | ||||
TQRTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLG

ITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
|||||.  | ||... ||.  .|.|| .||||.  |. |  ||| |...||.|. |.|.. . || ||||
ITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase MYO3B.AA YSK 43-309 43 2.5e-99 299.73 In-house 1-257 (257) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-257/257
Sequence Identity: 43% (117 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMD--EEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRC
. . | ||.| .| |||  ..| .   |.|..|  .. |  | |  | ..|  . |  .. |.|| . |     .  || . | | |||.  | |     
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLK-----DTKLWIIMEYCGGGSCLDLMKPKY-V

GKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGI
|. .||  |. ||   |.||  ||. | ||||.|  |.||. .| ||| ||||..|.| | ..||| ||||.||||||| .|    |.||.  |.|||||
GQ-FDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEV---SYYDFKADIWSLGI

TAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPD-SWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
||.|.  | ||. ..|| . .| || |.||.|   . |.   |  |.  || || |.|||   || | ||
TAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLE--GRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase MYO3B.AA SLK 43-309 40 1e-88 299.46 In-house 1-259 (259) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-259/259
Sequence Identity: 40% (108 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMD-EEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCG
||||  .| | .|||||  .|  . .|| |...  .. . |.   | .||  .  |||.|| |. .|  ..     ||...| |.|| | ..   ..  .
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYYYDNK-----LWMMIEFCDGGAVDNI---MVELE

KRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGIT
. | |  | |. .  . .|..|| ...||||.|  |||.| .|.|.| ||||||....|. .| | .|||.||||||..||   |  || . |.||||||
HPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGIT

AIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
 ||. ...||  || |...|.|| .  ||||. |  | .||. |. .|| || ..|..  .|..|...
LIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase MYO3B.AA S_TKc 43-309 33 1.4e-87 298.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-231/231
Sequence Identity: 33% (94 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNG--GSVTELVKGLLRC
.||...||||..|||||. .|..| . |.|...      | |. | .||.    |||.||.|..|.       . |..|.|.|.|  |.. .. |   | 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

GKR--LDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDA-RCDVWS
|.|  ..| .. ...|  ...|...| |.|||||.|  ||||..   .|. |||...||       .| .|||..|||||.        .|.  .||.||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWWS

LGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLD-------HPFI
.|.. .|.  | ||      ..|.||. .             .|. .||..|| || ||||..  .|        ||..
CGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MYO3B.AA KHS 43-309 40 1.9e-83 280.5 In-house 1-258 (258) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-258/258
Sequence Identity: 40% (111 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKV--LDPVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRC
.|..  .| |||| |||  ... ..||||||  ..|  |. . |  |  ...   .|||.| ..| . . |.     ||...| | |||. .    . . 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDF-AVIQQEIMMMKDC-RHPNIVAYFGSYLRRDK-----LWICMEYCGGGSLQD----IYHV

GKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGI
   | |  |.|.   .| ||..|| .  .|||.|| ||||| .| ||| |||||||.| |  .|   .|||.|||||| | |..    |.  ||.|..||
TGPLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK--GGYNQLCDIWAVGI

TAIELGDGDPPLFEMHPVKMLFKIPRNP--PPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
|||||..  ||.|..||.. || . .    ||.|   . | . | ||. ..|.|.  |||. ..|| |||.
TAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase MYO3B.AA Pkinase 43-309 27 1e-80 279.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEA-----EYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGG----SVTEL
..|...||.|..|.|||  .| .| . |||... ... ... ..     |  |.. | .|||.|..|..|.      .. ...|.|.|.||    .  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

VKGLLRCGKRL--DEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGV----KLVDFGVSAQL-TSTRLRRNTSVGTPFWMAPEVIACEQQYD
...  . ....  .| ..  ..|  | ||...| ..|||||.|  |||.  .| .    |. |||...|. .      .| .|||..||||||      .
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GG

SSYDARCDVWSLGITAIELGDGDPPLFEM----HPVKMLFKIPRNPPPTLLHPDSWC---------------------EEFNHFISQCLIKDFEKRPSVT
. |. ..|.||.|.. .|.  | ||  .     . . ....| |. .| |  . .|                      ||. .||. || || .|||. .
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

HLLDHPFI
..| ||..
QILQHPWF
Kinase MYO3B.AA PAKL 43-309 40 5.2e-79 268.81 In-house 1-256 (256) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-256/256
Sequence Identity: 40% (111 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDM-D-EEIEAEYNILQFLPSHPNVVKFYGMFYKA-DRCVGGQLWLVLELCNGGSVTELVKGLLR
 |. |  | | || |||.  |  .   |.||. ..    . ..|| | .||    . ||.|  .|      .     ..|  .. |  ||.  . .    
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVI-EIKESNEIKDIEKEIQILKKCKC-PNIVSYFGSIQQKLN-----HYWILMDYCSLGSINDMME---S

CGKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLR--RNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS
|.| |.|. || ||  .|.||  ||   |||||.|  ||||.  . ||. ||||| || .. ..   |  .|||.|||||.|         |.  ||.||
CCKTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDE-YDGQANQMIGTPYWMAPEIINKQN-----YNNKCDIWS

LGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
|||||||. || ||. .| | . .  ||. ||||.  |  |  .|| |. ||. || |||.|.  ||.||||
LGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase MYO3B.AA PAKA 43-309 36 1.1e-75 257.8 In-house 1-260 (260) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-260/260
Sequence Identity: 36% (100 aa)

WEIIETIGKGTYGKVYKVANKRDGSL--AAVKVLD-PVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLR
 . .| ||.|  |.||...|.. ..    |.|...    .. | |  |  ..     |.|.|...  .   |..    ||.|.|  .||. |....   .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKEC-KHKNIVNYIDSYLV-DDE----LWVVMEYMEGGCLTDVITQCCN

CGKR-LDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSL
     .||. |.|..   | ||. .| . .||||.|  |||| ..| ||. |||  ||||  ...||| |||| |||||||   |     ||   |.|||
IQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDIWSL

GITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
|| |||. .| ||  .. |.. .. |  |  | ...||.| .||. | ..|| .| ..|.|.. || |||.
GIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MYO3B.AA Pkinase_Tyr 43-309 23 7.6e-21 71.23 Pfam 1-270 (270) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-270/270
Sequence Identity: 23% (68 aa)

WEIIETIGKGTYGKVYK-VAN---KRDGSLAAVKVLDPVSDMD----EEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQ--LWLVLELCNGGSVTE
 ......|.| .|.||| ...   . ..   |||.| . .. .    |.  .| .|.  |..|||.|..||  .    . |..  ...|.|.. .|    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT----DQGEPNQIYIVMEYMPHG---D

LVKGLLRC---GKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQL-----TSTRLRRNTSVGTPFWMAPEVIACEQQ
| . | .    ...|.   .  . .    |...|. ...||||.   |.|.| .. ||  ||| .  .       .| | ..     .|||||.|.    
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGK-

YDSSYDARCDVWSLGITAIELGD-GDPP-LFEMHPVKMLFKI-PRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
    .    |||| |..  |.   |. |   .| .  .. .|  ..    .  |.  ..|  . . ||  .| |.||. . .  | ..
----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase MYO3B.AA TyrKc 43-309 24 1.1e-15 31.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 43-309
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

WEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEAEYNILQFL-PSHPNVVKFYGMFYKADRCVG---GQLWLVLELCNGGSVTELVKGLL
 . ....| | .|.|||   |      |||.| . .   |..  | .|.  | ..|||.|..||   .  |      ..|..|.|.. .|.   | . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGD---LKDYLR

RCGKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTST--------RLRRNTSVGTP-----FWMAPEVIACEQQY
.....|  .   .. . .  | ..|| ...||||    |.|.. .. ||  ||| |  ...           |  .. |.       |||||.|      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----N

DSSYDARCDVWSLGITAIEL-GDGDPPLFE-----MHPVKMLFKIPRN----PPPTLLHPDS----WCEEFNHFISQCLIKDFEKRPSVTHLLDHPFI
.. .    |||| |..  |.  .|..|  .     | .  .. .. .     .||  . |        .|    ..||   | |.||. . .  | ..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
MYSc MYO3B.AA MYSc 353-1075 33 2.7e-262 878.59 SMART 1-771 (771) Show / Hide 
Range on Protein: 353-1075
Range on HMM: 1-771/771
Sequence Identity: 33% (271 aa)

EDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNL-SIYSPQFSRLYH------GVKRSSNPPHIFASADNAYQCLVTFSKD
    |.   ||...|. | |..... |.|||.  .|||| |...||.||...|  ||.|.. ..|.      | .|. .|||||| |||||... . ...
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN

QCIVISGESGSGKTESAHLIVQHLTFLGKADNQTLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEK
|||.||||||.||||....| |.|....  . ... |.||| | . |||||| |  |.|||||||| |. |  .| . || |. ||||||||..|. || 
QCIIISGESGAGKTENTKKIMQYLAAVSG-QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGER

NFHIFYYIYAGLYHQKKLAEFRLPE----EKPPRYIAG------ETERV----MQDITSKESYRTQFEA----IQHCFKIIGFADKEVHSVYRILAGILN
|.||||...||.  .  . ||.| .     .  .|..         .       ...    .    |..    ... ....|| ..|.....||.|.|| 
NYHIFYQLCAGAS-EEQKQEFHLKPFSHNPEDYHYLNQGGHYWNN-K-RHQSQCFTVD-GIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILH

IGSIEFAAISS--QHQTDKSE-VPNPEALENAACVLCISSEELQEALTSHCVVTRGE---TIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQP
.| |||... .    |.  || |...|.|.||.  | ...|.|...||.  ..|..|   .|.....|  |.. |||..||.|.|||.|||.|||. .  
LGNIEFEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM--

DKNICSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYKNEGVDAVLVQYE--DNRPLLDMFLQK---PLGLLALLDEESR
        ..  .|.|||.||| |..|||||.||| .||. |..||.|.| ||| ||..||..   ...   || | .|   .|   |.|...|||||..
--------HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECM

F---PQGTDQTLVDKFEDN-----LRCKFFWRP------------KGVELCFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPL
|   |.|||||...|   .     .    ....            .  . .|.|.|||| | |.. | ||||.|||..|.. ....| |....|||.   
FHAQPKGTDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYE

TKT--GNLAQTRAKITASSRSLPPHFSAGRAKVDTLEVIRHPEETT----NMKRQTMASYFRYSLMDLLSKMVVGQPHFIRCIKPNDDRKALQFSQDRVL
..|   ...... .   .||.  .   ... |                    . .| .. |. .| .|....   .||.|||||||. .|. .| .|.||
DQTSQTPQEKSS-QGKNKSRRKKR-M-MQM-K-------------KTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVL

AQLRSTGILETVSIRRQGYSHRIFFEEFVKRYYYLAFRAHQTP---------PANKESCVAILEKSR---------LDHWVLGKTKVFLK-YYHVEQLNL
 |||  |.||.. ||| |...|. ..||..||. |..  ....            |..|.|||...           | . .||||||.. ..... |  
HQLRCCGVLENIRIRRAGFPYRWPYQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNPGQLFHLEE

LLRE
. ..
MRER
Myosin_head MYO3B.AA Myosin_head 598-1062 28 1.7e-134 457.94 Pfam 249-765 (765) Show / Hide 
Range on Protein: 598-1062
Range on HMM: 249-765/765
Sequence Identity: 28% (156 aa)

FEAIQHCFKIIGFADKEVHSVYRILAGILNIGSIE-FAAISSQHQTDKSEVPNPEA-LENAACVLCISSEELQEALTSHCVVTR----GETIVRANTVDR
|. ..  ..|||| ..| .|..||.|.||..| .. |.   .. |    .|.. |. .|...  .....||.. .|..  ..|.     |..... ....
FQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA---VVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQ

AEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAE-------------------------------DRMNVGILDIFGFEDF-QRNSFEQLCINIAN
| . |||..||.|.|.| |||||||      ..||. .                                .  .|.|||.||| | ..|||||.||| .|
AMYARDALAKAIYSRMFDWIVNRIN------QAICHKTQNTDDSDGQAAQWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCN

EQIQYYFNQHVFALEQMEYKNEGVDAVLVQY-EDNRPLLDMFLQK--PLGLLALLDEESRFPQGTDQTL----VDKF-EDNLRCKFF-WRP-K------G
|. |..||.|.| ||| ||..||..   ..|  || |  |  . |  |.|.|.|||||..||..||||.    .. . . ..| . |  .| .      .
EKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCD-LIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPR-LHFAQKPGRFYKRHRQ

VELCFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSEN-KLLQQLFSIPLTKTGNLAQTRAKITASSRSLPPHFSAGRAKVDTLEVIR--------
 . .| | |||| | |...| ||||.|.|. |.. ... | . ...|.||  . . .  . |                    ... . |           
GNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELFPDWEWAEWAHMQ-----------------IDFEADFHEEEFKRRYNRNGC

-HPEETTNMKR-QTMASYFRYSLMDLLSKMVVG---QPHFIRCIKPNDDRKALQFSQDRVLAQLRSTGILE-TVSIRRQGYSHRIFFEEFVKRYYYLAFR
  .  .  ..  || .. |. ..  |.  .       ||..||||||. ... ||....|| |||  |.|| .. |.|.|...|. . ||..||. |...
QKGKQGKKKWFMQTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPK

A------HQTPPANKESCVAILEKS---RL--DHWVLGKTKVFLK
.        . .. |. | .||..     .  . . .||||.|..
TWWSWIWPEWNGDTKQGCEKILQHLSWGNMDKEEYQFGKTKIFFR
Myosin_head MYO3B.AA Myosin_head 361-568 44 6.9e-91 313.05 Pfam 1-217 (765) Show / Hide 
Range on Protein: 361-568
Range on HMM: 1-217/765
Sequence Identity: 44% (96 aa)

EDDLVNLEVLDEDTIIYWLQKRYA-DALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKT
 .|.|.|. | |..... |.|||.   |||||.|...|..||...| ||.. .   |.| .|. .|||||| ||.||. ...  ..|||.|.|||| |||
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLPIYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAGKT

ESAHLIVQHLTFLGKADN--Q--TLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAV----MGARISEYLLEKSRVIQQAAGEKNFHIFY
|.. .. |......   .  .  .. |.||| | . |||||| |  |.||||||||.|. |. || .     |..|. ||||||||. |..|| ||||||
ENTKYVMQYFASVSGSNPGVNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHIFY

YIYAGLYHQKKLAEFRL
...||.  |. ..|..|
QLLAGASQQEEKKELHL
IQ MYO3B.AA IQ 1077-1097 23 0.169794 8.72 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1077-1097
Range on HMM: 1-21/21
Sequence Identity: 23% (5 aa)

MGRVVMLQAYTKGWLGARRYK
   ....||. .|.|  ..|.
HRAAIKIQAWWRGYLARKHYR
IQ MYO3B.AA IQ 1075-1097 30 0.390109 3.53 SMART 1-23 (23) Show / Hide 
Range on Protein: 1075-1097
Range on HMM: 1-23/23
Sequence Identity: 30% (7 aa)

EVMGRVVMLQAYTKGWLGARRYK
..   ....||.  |.|  .|||
RMHRAAIIIQAWWRGYLARKRYK
IQ MYO3B.AA IQ 1104-1124 47 6.6e-08 29.49 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1104-1124
Range on HMM: 1-21/21
Sequence Identity: 47% (10 aa)

EKGAITIQSAWRGYDARRKLK
.. ||.||..|||| ||....
HRAAIKIQAWWRGYLARKHYR
IQ MYO3B.AA IQ 1102-1124 47 1e-07 32.87 SMART 1-23 (23) Show / Hide 
Range on Protein: 1102-1124
Range on HMM: 1-23/23
Sequence Identity: 47% (11 aa)

KREKGAITIQSAWRGYDARRKLK
.... || ||..|||| ||.. |
RMHRAAIIIQAWWRGYLARKRYK