Gene NEK5 (Mouse)

NEK5

Species: Mouse
Alias: NEK5, BB049667
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK1

Sequence

Name Sequence Type Origin Length Description Download
NEK5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
NEK5.AA Protein Sugen 627 None Fasta, JSON
NEK5.NA RNA Sugen 2253 None Fasta, JSON

Protein domain

Protein domains of NEK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK5.AA NEK1 4-255 63 8.70000000001e-198 663.37 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-276/276
Sequence Identity: 63% (175 aa)

FHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTK----EKEASKNEVILLARMEHPNIVTFFSSFQENGR--LFIVMEYCDGGDLMQRIQRQ--RGVM
.| ||.||||.|||..|.|.|....|.|||||...|    |.|.|.|||..||.|.|||||....||.|||.  |.|||||||||||||.|.||  .|..
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLS--KNGM--------------VAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNN
||||||..||.||.|.|.|||||||||||||||||||.  ||||              ..||||||.||.||..||.|.||.|||||||||||||.||||
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
|.||||||||||||||||||||.||...||||||||...||.||.|..||||..|.|...|..||||...|.|||.
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase NEK5.AA NEK 4-255 48 3.5e-162 545.11 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-286/286
Sequence Identity: 48% (140 aa)

FHLIKIIGEGTFGKVYLAKDKSESSH-----CVIKEISLT----KEKEASK-NEVILLARMEHPNIVTFFSSFQENG--RLFIVMEYCD-GGDLMQR---
. .|| ||.| |||||....|| ..|     .|.|.|...    |||...  |||..|... |||||... ||.|..  .|.||||||. ||||.|.   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IQRQR--GVMFSEDQILCWFVQISLGLKHIHDR-----KILHRDIKSQNIFLSKNGM---VAKLGDFGTARTLNDSMELAQT-CAGTPYYLSPEICQNRP
|..|.  | .|.|.||. ||.|..|.||..|||     ||||||||.|||||.||..   ..|.|||| .. ||.....|.| . |||||.|||.|||.|
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNNKTDIWSLGCVLYELCTL--KHPFESN--NFHHLVLKICQG-RVAPISPH--FSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
|||| |||||||||||.|||  |||||..  |...|..||..|   .||..|  .|.|||.|| |.....|..|||....|..||.
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase NEK5.AA NEK8 7-255 37 4.5e-115 330.01 In-house 4-278 (278) Show / Hide 
Range on Protein: 7-255
Range on HMM: 4-278/278
Sequence Identity: 37% (104 aa)

IKIIGEGTFGKVYLAKDKSES--SHCVIKEISLT----KEKEASKNEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGVMFSED-
|  .| | || . |   |. .  .  ..|.| ..    ||  .  ||. .|.. .||||.  . .| |.. |.|.|||.||| | | ||.|..  |.|  
IRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFEEER

----------------QILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQ--TCAGTPYYLSPEICQNRPYNNKT
                .||  |.|..... |.|.  |||||.| ||||. .  || |.|||| .  .|.    .   |  |||||.|||.|. .|||.| 
QLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKS

DIWSLGCVLYELCTLKHPFESNNFHHLVLKICQG-RVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
|.|.|||||||.|.||  ||  |   ||.|| |.   .||| | | .. .|. ..  . |. |||.  ....| .
DMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase NEK5.AA NEK4 4-255 41 1.8e-107 363.36 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-257/257
Sequence Identity: 41% (108 aa)

FHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLT----KEKEASKNEVILLARMEHPNIVTFFSSFQ-ENG-RLFIVMEYCDGGDLMQRIQRQRGVMFS
.  .| .| | .| |.| . .      |.| . |     .|. |   |. || .. |||||... |.. |||  |.||| .|.|||| .. ..|.. . .
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

EDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLK
| |.. ||||| ..|  .|...||||| | ||||| |  .. |.|||| .| ||.. ..|.|  |||||.|||.  ||||. | ||||||| .||. |||
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNII-KIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLK

HPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
| |.  .   |. .| ||.  |..| .| ||| |. |.    |..|||. .... |..
HAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase NEK5.AA S_TKc 4-255 30 2.3e-94 320.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

FHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKEASKNEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDG--GDLMQRIQRQRG----VMFS
......||.|.|||||....|.   .. ||.|.     |  ..|. .| .  |||||... .||. ..|..|||||||  |||...|.....    . |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

EDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNN-KTDIWSLGCVLYELCTL
| .. ... || ..|...|...|.|||.| .||.|..   . |..||| || |        |. |||.|..||..   .|.  | |.||.||.|||... 
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

KHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLK-------RPFL
. ||.    .....|..           |... ..| ..... |..||..  .|.        |..
YPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK5.AA NEK-Unclassified 4-255 40 7.1e-85 280.91 In-house 1-258 (258) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-258/258
Sequence Identity: 40% (104 aa)

FHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKEASKNEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGV--MFSEDQI
.  |  .| |  | ||| . .    | | . ||  | |   .| .|.|. . || |||.  || || .||   .|||||.| .|||..|.    | |  |
YDKITTLGQGGGGAVYLVRHQISKRHLV-QQISKRKKKKKRQNKIIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFDEGRI

LCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLKHPFE
  |..|.   .  || |||.||| | ||||| .  .|  .|||| .|....  . |.|| ||. ..|||.||  ||||. |.|||||..||.||    | 
MQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVS-MGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEPFFD

SNNFHHLVLKICQGRV------APISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
  |   .  || |.         |.|  .| ||| .|  . |  .| ||| | ..  .. 
THNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase NEK5.AA Pkinase 4-255 27 1.3e-84 292.16 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

FHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKE----ASKN--EVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGG----DLMQRIQ-RQR
.|....||.|.||.||....|...   ..|.|.. .||.    .  .  |. ...|. |||||... .|...... .|||||.||    ||. .|. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GVM-FSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVA---KLGDFGTARTL-NDSMELAQTCAGTPYYLSPEICQ-NRPYNNKTDIWSL
|.. |||... ... ||  ||...|...|.|||.|..||....|| ..   |..||| |. . . . . ..| .|||.|..||... ...|  | |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVLYELCTLKHPFESN------NFHHLVLKICQGRVAPISPHFS--------------------RDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
||.|||... . || .       .  ... .| ....   .|  .                    ......|  .... |..||. . .|. |..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NEK5.AA CAMK 9-255 18 1.9e-77 248.93 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-255
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

IIGEGTFGKVYLAKDKSES------------SHCVIKEISL------------------------------TKEKEASKNEVILLAR-------MEHPNI
..|.|.||||.|...|.               .. || |.                                | ..  ..|. .. .       . ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VTFFSSFQENG-------------------RLFIVM---EYCDGG----DLMQRIQRQRG-------------VMFSEDQILCWFVQISLGLKHIHDRKI
. ..  .. .                    ....||   |||.||    || ..|.....               |.|..   .| ||  .....|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKSQNIFLSKNG----------------MVAKLGDFGTARTLNDS-----------------------MELAQTCAGTPYYLS-PEICQN------
 |||.|  || |..|.                   |. ||| |. ....                        .. .|. |||.| . ||. .       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RPYNNKTDIWSLGCVLYELCTLKHPFESN-------------NFHHLVLKICQGRVAPISPHFSR-----------------------DLQS
        ..|. |.|.||.|..|| . . . ||..              | . |  ||..|.   ..|.||                        . ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIPQLFRVSPQDRPSVTSLLKRPFL
|| .. .| |..|....  |. |..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase NEK5.AA ULK 4-255 28 2.6e-75 256.5 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-329/329
Sequence Identity: 28% (93 aa)

FHLIKIIGEGTFGKVYLAKDKSE----SSHCVIKEISLTKEKEAS------------KNEVILLARME--------HPNIVTFFSSFQENGR--LFIVME
..|....|.|.||||| ...|         ...| |.. |... .            |||. .. ..         ||||| ..  |..     ..|.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCDGGDLMQRIQRQRG--------VMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNG-----------MVAKLGDFGTARTLNDS-M--E
||.||||.| |.....          .||....  | ||  |.|..|...| ||||| ||| ....            .|.|..||| |...... |  .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LAQTCA------GTPYYLSPEICQNR----PYNNK-TDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVA------------PIS-------PHFS
...||       |||.| .|.| |..    ||... .|||||||..||. . | ||... |  ..|.|.|  .             |.        |..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

RDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
 ....|| ... . . || | . |.. |..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase NEK5.AA STE 4-255 24 4.8e-72 245.67 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-359/359
Sequence Identity: 24% (90 aa)

FHLIKIIGEGTFGKVYLAKDKSES-SH--------------CVIKEISLTK-------------------EKEASKNEVILLARME--HPNIVTFFSSFQ
. .|..||.|.||.||.|...  .  |              . ||...| .                   |..  ..|. .. ..   |||||... .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ENG-------RLFIVMEYCDGGDLMQRIQRQRGVMFS------------EDQILCWFVQISLG-LKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTA
 .|        |.|.|||.||| | . |..  |. ..            |.|| .  .||  | |...|. .| |||||..||.|      .|| |||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

RTLNDSME----------------LAQTCAGTPYYLSPEICQN------RPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQG----------
  |.|||                   .|..||| . .||. |.       .|. | |||||||.. |..| |.|.   . .   . | ..          
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----RVAPISP-------------------HFSRDLQSLIPQLFRVSPQDRPSVTSLLK--RPFL
        |. .                   ..| ...  | . ..  |..||... |||   ||.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase NEK5.AA NEK11 4-255 42 2.9e-71 243.09 In-house 1-259 (259) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-259/259
Sequence Identity: 42% (111 aa)

FHLIKIIGEGTFGKVYLAKD---KSESSHCVIKEISLTK----EKEASKNEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQ--RQRGV
. | . .| | || |||  |   |      |.||||       |      |  ||.|..|| || |  || |     |. |||.| || .|||  .| | 
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQDNFCIITEYCEGRDLDYRIQEYKQAGK

MFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELC
.|.| ||. ||.|. ||   .|.|.|||||.||.|||| || .. |.|||| .| |  | .|| |  ||| |.|||  .   |  | ||||| |.|||.|
IFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFL-KNNLL-KIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMC

TLKHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
 . | |   ||  .||.|  |    .   . |.| ... ..   .|  |||   .|| |..
CMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase NEK5.AA ULK 4-255 28 3.1e-71 242.99 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

FHLIKIIGEGTFG-KVYLAKDKSE---SSHCVIKEIS---LTKEKEAS---------KNEVILLARME---HPN--IVTFFSSFQENGR--LFIVMEYCD
. |....|.|.|| ||| ...|       .  .| |.   . | |  .         |||. ..  .    |||  || ..  |..     ..|.||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLMQRIQRQRG-------VMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNG-----------MVAKLGDFGTARTLNDSM---ELAQT
|||| | |.....         .||....  | ||  |.|..|...| ||||| ||| ....             |.|..||| |..... .    . ||
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

CA------GTPYYLSPEICQNR----PYNNK-TDIWSLGCVLYELCTLKHPFESNNFHHLVLK--------------ICQGRVAPIS----PHFSRDLQS
|       |||.| .|.| |..    ||... .|||||||..||. . | ||.|. |  ..|.              |..  . . .    |..| ....
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIPQLFRVSPQDRPSVTSLLKRPFL
|| ... . . || | . ... |..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase NEK5.AA Pkinase_Tyr 4-196 25 4.9e-32 109.12 Pfam 1-210 (270) Show / Hide 
Range on Protein: 4-196
Range on HMM: 1-210/270
Sequence Identity: 25% (54 aa)

FHLIKIIGEGTFGKVYLAKDK----SESSHCVIKEI--SLTKE---KEASKNEVILLARM-EHPNIVTFFSSFQ-ENGR--LFIVMEYCDGGDLMQRIQR
 ...| .||| ||.||... |    ..  .. .| .  . ..|   .|.  .|. ..  .  ||||| .      . .   ..|||||. .|||    ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q--RGVMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTL-NDSME-LAQTCAGTPY-YLSPEICQNRPYNNKTDIWS
.   .  ..  ..|.. .||. |. . ..... |||.   |. ...|. |.| .||| ||.. ||.    ... .  |   ..||  ... .. |.|.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGCVLYELCTL
 | ...|..|.
FGVLMWEIFTY
Kinase NEK5.AA TyrKc 4-255 22 2.1e-29 104.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-255
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

FHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKEASKNEVILLARM--EHPNIVTFFSSFQEN-------GRLFIVMEYCDGGDLMQRIQRQRGV
 .|.|..||| ||.||... |     . .| .   . .|.  .|  .. .   .||||| ..    .        . |.|||||...||| ..... |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

MFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDS-----MELAQTCA---GTP-----YYLSPEICQNRPYNNKT
 .. .. | . .||. |  ..|.... |||.   |. ...|. ..| .||| .| . |       .   . .   |.        ..||  . . .. |.
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIWSLGCVLYELCTL-KHPFES-----NNFHHLVLKICQGRVAPISPH--------FSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFL
|.|| | ...|..|. . | .       .  ... .. ||.  |. |.         . .. ... |  .  | |||. . .  . ..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF