Gene NEK6 (Mouse)

NEK6

Species: Mouse
Alias: NEK6, Nek6
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK6

Sequence

Name Sequence Type Origin Length Description Download
NEK6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 261 Kinase domain by global Sugen HMM Fasta, JSON
NEK6.AA Protein Sugen 313 None Fasta, JSON
NEK6.NA RNA Sugen 1494 None Fasta, JSON

Protein domain

Protein domains of NEK6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK6.AA NEK6 45-296 88 4.90000000001e-215 714.62 In-house 1-252 (252) Show / Hide 
Range on Protein: 45-296
Range on HMM: 1-252/252
Sequence Identity: 88% (222 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLI
||||||||.|||||||.|.||.|.|.||||||||||||||||||||.|||.|||||||||.|||..||||.||||||||||||||.|.|||.||||||||
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKRLI

PERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ
||||.||||||||||.|||||.||||||||||||||||.||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||
PERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ

SPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDI
||||||||||.|||.|||||||||||..||||.||.||.|||.|||..||||
SPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase NEK6.AA NEK 45-296 41 5.5e-145 487.96 In-house 1-277 (286) Show / Hide 
Range on Protein: 45-296
Range on HMM: 1-277/286
Sequence Identity: 41% (117 aa)

FQIEKKIGRGQFSEVYKATCLLDRKT-----VALKKVQIFEMMDAKARQDCV-KEIGLLKQLNHPNIIKYLDSFIEDN--ELNIVLELAD-AGDLSQM--
..| ||||.|.|..|||. .  | |      ...||.. ...|. | .|... .|. .||||.||||.|| |||||..   |.|| | ..  |||.|.  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR-----RVMHRDIKPANVFITATGI----VKLGDLGLGRFFSSETTAAHS-LVGTPYYMSPERIHEN
 ||  |... ...|...|..|.|.|.|. .||.|     ...||||||.|.|.|. ..    ||.||.|. . ....|..|.. .|||||||||| ... 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GYNFKSDIWSLGCLLYEMAALQS--PFYG-DKMNLFSLCQKIEQC-DYPPLPGEH-YSEKLRELVSMCIYPDPDHRPDI
.||.|||||||||.||||..|..  ||.. | ||. ||. || .. .|||.|  . ||..|..|.|... .||..||..
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSC
Kinase NEK6.AA S_TKc 45-310 30 1.9e-93 317.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 45-310
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADA--GDLSQMIKYFKKQK-
..| .|||.| |..|||..   . . ||.|..           ..  .|| .||. .||||.|..|.| . ..| .|.|..|   ||| ..||  .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-RLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNF-KSDIWSLGCLLYE
 . .|| ....|. |.|.|.|..||....|||.||.|....    .|..| || |..       ....|||.||.|| .   ||.. |.|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQ--VARQMHVWT
|.. . ||.    ... . .||             |. ...... |   ||..|| .  . |  ..  .| | 
MLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK6.AA NEK8 82-295 42 4.9e-90 257.23 In-house 39-268 (278) Show / Hide 
Range on Protein: 82-295
Range on HMM: 39-268/278
Sequence Identity: 42% (99 aa)

MDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPER----------------TVWKYFVQLCSAVEHMHS
|. | ||.   || .|. |.||||| |.|.|.||| | |..| || | | |||    . | . .||                ..  ||.| |||| |||.
MSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQH-QQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQ

RRVMHRDIKPANVFITAT-GIVKLGDLGLGRFFSSETTAAHS--LVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIE
  . |||.|..|.| |   ..||.|| |.    .... .. .  .||||||||||      ||.|||.|.||| ||||. |   | ..  ||  |. || 
HNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEAS--NLPALVWKIM

QC-DYPPLPGEHYSEKLRELVSMCIYPDPDHRPD
||  | |.. .|||  .| ||. |   ||. ||.
QCRAYEPIS-DHYSNEMRMLVHNCLQQDPEQRPS
Kinase NEK6.AA NEK1 45-294 37 1.1e-79 271.04 In-house 1-265 (276) Show / Hide 
Range on Protein: 45-294
Range on HMM: 1-265/276
Sequence Identity: 37% (102 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKR
. . |.|| | |  .....   |... ..|  .. .| . | |.. ..|  .|. . ||||.|| .||.|     | || | .|.||| | |.  | .  
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQE-KEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

LIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFIT--ATG---------------IVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYN
|..| .   .|.|.| |. |.|.|...|||||. |.| |    |               .||||| |  |  ....  |   .||||| ||| .   .||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

FKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRP
 ||||||||| |||  .|  || . ..    |  || |  |||.|  |||..|..|||     .| |||
NKSDIWSLGCVLYELCTLKHPFEANNWK--NLVLKICQGTYPPIP-PHYSYELQSLVSQMFKRNPRHRP
Kinase NEK6.AA Pkinase 45-296 27 5.7e-78 270.14 Pfam 1-284 (293) Show / Hide 
Range on Protein: 45-296
Range on HMM: 1-284/293
Sequence Identity: 27% (80 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCV-KEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAG----DLSQMIKYFKK
..|..|||.| |..|||..   ..|.||.|..   .  . | ...    || ..| ||||||....|.| ..... .|.|... |    ||. .|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

QKRLI--PERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIV----KLGDLGLGRFF-SSETTAAHSLVGTPYYMSPERIH-ENGYNFKSDIW
... .  .|... .|. |.....|..||....|||.||.|..|  .| .    |..| || ..|     . .....|||.||.|| |   ..|  |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCLLYEMAALQSPFYGD----KMNLFSLCQKIEQCDYPPLPGEHYS-------------------EKLRELVSMCIYPDPDHRPDI
|.||.||||.  . ||.|.    ...   . ..| .....    . .|                   | ...... |. .||  || .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA
Kinase NEK6.AA STE 45-295 24 2.1e-73 250.19 In-house 1-347 (359) Show / Hide 
Range on Protein: 45-295
Range on HMM: 1-347/359
Sequence Identity: 24% (88 aa)

FQIEKKIGRGQFSEVYKATCLL---------------DRKTVALKKVQIFEM--------------MDAKARQDCVKEIGLLKQLN--HPNIIKYLDSFI
... .|||.| | .|||| .                   . .| |.. . .               .. . .|.  ||| ..|..|  ||||.||.....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------NELNIVLELADAGDLSQMIK-YFKKQKRL---------IPERTVWKYFVQLCSA-VEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGR
 .       .||.|..|. |.| |...|| .....|.|         .||  . .. .|.. .  .. || ...||||||||...     ||| | |.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFSSE--------------TTA--AHSLVGTPYYMSPERIHE------NGYNFKSDIWSLGCLLYEMAALQSPFYG-DKM-NLFSLC--QKIEQ------
 ....              |..    ..|||| .|.||.|        .||..|.|||||||.. |||  . |.     | ..|     ....|      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---CDYPPLPG------------------EHYSEKLRELVSMCIYPDPDHRPD
    . ||||                   ...|..... .. |   ||..||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase NEK6.AA NEK2 45-296 34 2.3e-66 222.45 In-house 1-310 (319) Show / Hide 
Range on Protein: 45-296
Range on HMM: 1-310/319
Sequence Identity: 34% (108 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFI--EDNELNIVLELADAGDLSQMIKYFKKQKR
 .. . ||.| |  ..|     | |  . |  .  . |. | .|  | |. .|.|| ||||..| |  |  .   | || |    ||||||||  .|...
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEIC-YGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQ

LIPERTVWKYFVQLCSAVEHMHS---------------------RRVMHRDIKPANVFITATGI------------------------------------
 ..|  .|. . |||.|    |                      . ..||||||||.|  . .                                     
YMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYS

---VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELV
   ||||| || |    .|  ||. |||||||||| .|   || ||||||.|||.|||.||  || .   |   |  || |  . ..| . ||. | |..
QVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQA--TNQAQLQEKIKQGHFRRIP-YQYSRHLNEII

SMCIYPDPDHRPDI
.  |  |. ||| |
HFMINVDHYHRPSI
Kinase NEK6.AA ULK 45-293 26 3.5e-66 226.18 In-house 1-312 (324) Show / Hide 
Range on Protein: 45-293
Range on HMM: 1-312/324
Sequence Identity: 26% (82 aa)

FQIEKKIGRGQFS-EVYKATCLLD---RKTVALKKVQIFEMMDAKAR-------QDCVKEIGLLKQLN---HPN--IIKYLDSFIED--NELNIVLELAD
... ...| |.|   |||...  .    . || |......| . | .       |   .|| ..|.|.   |||  |.|..| | ..  | . |..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLSQMIKYFKK-----QKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITAT------------GIVKLGDLGLGRFFS---SETTAAHS
 |||.| ||  ||      |. ..|  . ..| |.|..  ..|.. ..||||||.|  |.              |..|..| |.....     | .  ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGDKMNLF----SLCQK-------IEQ--CDYPPL-PGEHYSEKLREL
.|      |||.||.|. ....|    |. .|.|||||||..|||   . ||........    .| ..       |..   ..|.  .. . |.....|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VSMCIYPDPDHR
 . ..  |.. |
IRRMLQYDEKDR
Kinase NEK6.AA ULK 45-293 24 5.5e-66 225.52 In-house 1-317 (329) Show / Hide 
Range on Protein: 45-293
Range on HMM: 1-317/329
Sequence Identity: 24% (79 aa)

FQIEKKIGRGQFSEVYKATCLLDR----KTVALKKVQIFEMMDAKARQD-------CVKEIGLLKQLN--------HPNIIKYLDSFIED--NELNIVLE
... ...| |.|  |||...  .     . || |......|   .  |.         .|| ..|.|.        ||||.|..| | ..  | . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LADAGDLSQMIKYFKK------QKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITAT------------GIVKLGDLGLGRFFSSE---TT
. . |||.| ||  ||       |. ..|  . ..| |....  ..|.....||||||.|. |.              |..|..| |........     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AAHSLV------GTPYYMSPERIHENG----YN-FKSDIWSLGCLLYEMAALQSPFYGDKMNLF-----SLCQK---------IEQCDYPPL-PGEHYSE
 ... |      |||.||.|. ....|    |. .|.|||||||..|||   . |||. .. ..     .| ..          .. ..|.  .. . |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

KLRELVSMCIYPDPDHR
....| . ..  |.. |
ECKDLIRRMLQYDEKDR
Kinase NEK6.AA NEK4 45-305 36 4.2e-64 219.28 In-house 1-257 (257) Show / Hide 
Range on Protein: 45-305
Range on HMM: 1-257/257
Sequence Identity: 36% (95 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSF-IEDN-ELNIVLELADAGDLSQMIKYFKKQKR
... | .|.| . ||.      |.|   .||..     . . |..  .|. || || ||||..| .|. ||..  | ||.   . ||| .  |  ..   
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFL-KNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLK--QQKNQ

LIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA
...|. |   |||   |   || ....||| |  |.|.| . |.|.||.|. |        |  ..|||||||||      |..||||||||| .|||. 
FLEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMIT

LQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQ
|   |    ||  ||  .| |   ||.|   ||. | .||   .   |. || |  . |    
LKHAFDAKDMN--SLIYQIIQGQPPPMP-PNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase NEK6.AA Ciliate-E2 45-296 23 4.5e-62 211.86 In-house 1-356 (365) Show / Hide 
Range on Protein: 45-296
Range on HMM: 1-356/365
Sequence Identity: 23% (87 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALK-------------KVQIFE----MMDAKARQDCVKEIGLLK----------------QLNHPNIIKYLDS
. . ||||.|.|. |||..  ...| .|.|             ||.|..    .|  .  .   .|| ...                |||||||||. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI--EDNELNIVLELADAGDLSQMIKYF-KKQKRLIP------ERTVWKYFVQLCS---------------AVEHMHSRR-VMHRDIKPANVFITATGIV
|.   || . .|.|... ||| . || . ||..  |.      |. . ... |...               |.|..||.  ..|||||| |...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDLGLGRFFSSETT-------------------------------AAHSLVGTPYYMSPERIH---------ENGYNFKSDIWSLGCLLYEMAALQSP
|. |.|| .... .                                  .....|||.||.|| .          ..||..|.||||||..||||   . |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGDKMNLFSLCQKIE-QCDYPPL--------------PGEHYSEKLRELVSM----CIYPDPDHRPD-I
|         . |... ..|.|.                 .. |..   | .     ..  ||. |.. .
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGW
Kinase NEK6.AA TyrKc 45-303 22 6.4e-30 106.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 45-303
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL--NHPNIIKYLDSFIED-------NELNIVLELADAGDLSQMIK
 . .||.|.|.| ||||.|      .|| |...         |.|  .|. ....|  .||||.. .   ...         | ||.|... ||| . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

YFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSE--------TTAAHSLVGTP-----YYMSPERIHEN
. ...   .. ..  .. .| ..  |. ||... |||.   |. ... ..|| .| || |.  ..        .  . .  |.        |.|| | ..
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYNFKSDIWSLGCLLYEMAALQSPFYGD----KMNLFSLCQKIEQCDYPPLPGE-------HYSEKLRELVSMCIYPDPDHRPDIVYVHQVA
 ...|||.|| | ...|.  .  . | .    .|. . . ....| ...| | .       . .... .. ..|   ||. ||    .|.  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase NEK6.AA Pkinase_Tyr 45-240 27 2.2e-25 86.58 Pfam 1-207 (270) Show / Hide 
Range on Protein: 45-240
Range on HMM: 1-207/270
Sequence Identity: 27% (59 aa)

FQIEKKIGRGQFSEVYKATCL----LDRKTVALKKVQIFEMMDAKA--RQDCVKEIGLLKQL-NHPNIIKYLDSFI-EDNE--LNIVLELADAGDLSQMI
 .. ||.|.|.| ||||.|.      .. .|| |..   |  . ..  |.|  .|. ..||| .||||....   . ..    . ||.|..  |||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL---

KYFKKQ---KRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFF--SSET-TAAHSLVGTPYYMSPERIHENGYNFKS
.| .|.   |. ..  .  .. .| ... |. .|..  |||.   |. .| ...|| .| || |     ..  .....       |.|| |... .. ||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DIWSLGCLLYEM
|.|| | |..|.
DVWSFGVLMWEI