Gene NIM1 (Mouse)

NIM1

Species: Mouse
Alias: NIM1, E130304F04Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: NIM1

Sequence

Name Sequence Type Origin Length Description Download
NIM1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
NIM1.AA Protein Sugen 436 None Fasta, JSON
NIM1.NA RNA Sugen 2274 None Fasta, JSON

Protein domain

Protein domains of NIM1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NIM1.AA NIM1 74-325 69 7e-250 742.19 In-house 1-258 (258) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-258/258
Sequence Identity: 69% (180 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILD--KTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEP
||..||||.||||.||||.|.||||||||||.|  |||.||||||.|||||..||..|||||||||||||||...|||||||.||||...|..||||.|.
YRFCGEIGRGNFSKVKLGVHQLTKEKVAIKIMDLDKTKMDQKTQRMLSREIQCMECMHHPNIVRLYEVVETLTRVHLVMEYARGGELYTHIHQEGKLREI

ESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKK----GEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTG
..|.||.||.|||||||...|.|||.|||||.|||..||||||||||...|.    ..|||||||||||||||||.|.||.|.|||.||||.|||||.||
HCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDFGFSCYCKMGTGANQMLNTFCGSPPYAAPELFQDEHYIGEYVDVWALGILLYFMMTG

TMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
.||||||||.|.||.||.|.|.||..||.||||||||.|...||.||.|...|...||
VMPFRAETVPKMKKCILKGQYQIPDYVSLPCHRLIRGMLKHIPTQRYTIDQMMNHQWM
Kinase NIM1.AA CAMKL 74-325 39 3.7e-139 446.83 In-house 1-297 (297) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-297/297
Sequence Identity: 39% (118 aa)

YRIRGEIGSGNFSQVKLGIH-SLTKEKVAIKILD--KTKLDQKTQRL-----------LSREISSMEKLH---HPNIVRLYEVVETLSK------LHLVM
|||  ..| |.|..|||..| ..|.|||||||.|  |...|.....            . |||. |..|.   ||||..||||.|| ..      ..|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAGGGE--LFGKISTE----GKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRT--CVKVGDFGFSTVSKK-----GEMLNTFCGSPPYA
||..|||  || .|  .    |...|.| . .| ||.|||...|.. |.|||.|.||.  ...    .|. |||||.  ..     |..|.||||||||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFRD--QHYVGVYVDIWALGVLLYFMVTGTMPFRAETVA---------KLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
|||.| .  ..| |  ||||..||.||.||.|..||...|..         ..|. .. . ..|. ||| .|..|||. ||. |..|. |  ||. .||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase NIM1.AA MARK 74-325 46 4.7e-123 403.99 In-house 1-262 (262) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-262/262
Sequence Identity: 46% (122 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQ-KTQRLLSREISSMEKLHHPNIVRLYEVVE--TLSK-LHLVMEYAGGGELFGKISTE--GK
|..  .|| |....|||..| .|..||||||..|.||.  .. . . |||. | ||.||||..|..|.|  | .. ..|.||||.||||.. |     |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRT--CVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMV
|.|.| . ||.||.|||. .|.. |.|||.|.||.   ...   .|  |||||.  . |..||||||.|||.|||.|  . | |  ||||.|||.|||||
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGTMPFRAET--VAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
.|. ||.. |    .|.| || | |.|| |||  |. ||. .|.. | ||  |  ||. .||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase NIM1.AA CAMK 79-325 26 2.3e-120 389.76 In-house 1-425 (425) Show / Hide 
Range on Protein: 79-325
Range on HMM: 1-425/425
Sequence Identity: 26% (111 aa)

EIGSGNFSQVKLGIHSLTK------------EKVAIKILDKTKLD--------------------------QKTQRLLSREISSMEK-------LHHPNI
..|.|.|..|||.|| .|.            .||||||.||.||.                          .|... . |||. | |       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYEVVE------------TLSK--------LHLVM---EYAGGGEL----FGKISTE---------------GKLSEPESKLIFSQILSAVKHMHENQ
..|||| |            | ||        ...||   ||. ||||    | .|                  |...| | . .| ||.|||...|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKAENVFYTSRT-----------------CVKVGDFGFSTVSKK------------------------GEMLNTFCGSPPYAA-PELFRD-----
|.||||| ||. ....                   .|. ||||... ..                        |....||||.|.|.| ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QHYVGVYVDIWALGVLLYFMVTGTMPFRAE-------------TVAKLKKSILEGTYT-IPQH-----------------------VSEPCH
        . |.|  .|.|..||.||.|..|..||...             .  .|.. |..| |. .| .                       ||. | 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

RLIRGVLQPTPTERYGINYIMSNEWM
 |||. ||. |..|. |  ... .||
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase NIM1.AA AMPK 74-325 45 4.6e-117 349.05 In-house 1-254 (254) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-254/254
Sequence Identity: 45% (115 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-DQKTQRLLSREISSMEKLHHPNIVRLYEVV-ETLSKLHLVMEYAGGGELFGKISTEGKLSEP
| |   || | |  ||.|.| ||.||||||||.|.|. ||...  ..|||. . .. ||.|..||||. || . . .||||. |||||  |   |.|.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

ESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPF
|..  | ||.|.|  .|.. | ||||| ||.      ..|. ||| | . |.||.| | |||| |||||.   . |.| .||||  || || |. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

RAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
  | ...| | |..| |.||...|. .. ||.. ||. |..|. |. |.  .| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase NIM1.AA QIK 74-325 41 3.5e-107 362.38 In-house 1-272 (272) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-272/272
Sequence Identity: 41% (114 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK------
| |   || |||  |||. |  ||.||||||.||..||..    . ||.  |  | ||.|..||.| || . . .|.||. .||.|  .   |.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVD
              ..|.| . .|.||.|||.. |. .|.||||||||.   .   .|. |||||  .|.|..|.|.||||||||||.|  . | |  ||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

IWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
|| .||.|| .|.| .||  .|. .|....|.| . ||  .|. |  |||  |   |. || |. |.   ||
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase NIM1.AA NuaK 74-325 42 3.5e-99 261.37 In-house 1-252 (252) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-252/252
Sequence Identity: 42% (107 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQ-RLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPE
|..    |.| .  |||..   |  .||||   | | . .   .   |||  |  |.||.|.  ||| |  .|. .||||| ||||.  ||  ..|.| |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

SKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFR
 . .| || |||   | ..|.||||| ||.       .|. ||| | . .....|.|||||| || ||    | | |  || |.|||||| || ||||| 
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

AETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
 .   .|.| | .| |  |.. |. |  |||  |.  |. |  |  | .  |.
GHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV
Kinase NIM1.AA S_TKc 74-325 31 5e-94 319.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGG--GELFGKISTEGK----
|.|  .||.| |..|....|  |...|||||..         . . |||. ..| ||||||.||.| .. ..|..||||..|  |.||  |   |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGV-YVDIWALGVLLYFM
  ..| . . .. ||..|....|...||||||| ||.. ..  ..|..|||....       .||||.| | |||..      |   .|.|..|..|| |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

VTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMS-------NEWM
..|  ||.  ..... | |.          |...  .||. ||  |..|...  ..         .|.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NIM1.AA Pkinase 74-325 31 1.2e-83 288.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSR--EISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGG----ELFGKIS--TE
|.| . ||||.|..|....|  | ..||.||..| . . . .. . |  ||. | .|.||||||||...|. .....||||..||    .||  ||   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--SEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCV----KVGDFGFSTV--SKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWAL
|..  || | | .. |||......|.. ||||||| ||... ..  .    |..|||.. .    ... ..||||.|.|.|||. |.. | |  ||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYFMVTGTMPFRAE------TVAKLKKSILEGTYTIPQHVS---------------------EPCHRLIRGVLQPTPTERYGINYIMSNEWM
|..|| |..|  ||. .      .  .. . |... .  .   .                     |.|  .|.. |.. |..|...  |.  .|.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NIM1.AA TSSK 74-325 34 2.9e-77 253.15 In-house 1-289 (289) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-289/289
Sequence Identity: 34% (100 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEK----------------VAIKILDKTKLDQK-TQRLLSREISSMEK-LHHPNIVRLYEVVETLS-KLHLVMEYAG
|     ||.|... |... .  .| |                ||||| |..|     ... | |||. | | |.||||...||  || . |  .||||| 
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGELFGKISTE------GKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGE------MLNTFCGSPPYAAPELF
.| |. .| .       | |.|..... |.|. ||||..|   . ||||| ||..   . ..| .||||. . ....      .. |||||  ||||| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

RDQHYVGVYVDIWALGVLLYFMVTGTMPFRA--ETVAKLKKSIL--EGTYTI--PQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
|   | .  .|.|..|| || ||.|.|||      . |. . .   . ....   ...|. |  |||  ||| |..|. || |....||
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase NIM1.AA RSK 74-325 32 1.7e-74 253.81 In-house 1-278 (278) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-278/278
Sequence Identity: 32% (91 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQK--TQRLLSREISSMEKLH-HPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGK---
 .  |..| | .....  .|. |.   | |.|.| |..|.  ..|   .|.. .|    ||.||.|... .| .||.|.|||  ||||| ....|.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTS---RTCVKVGDFGFSTV-SKK-GEMLNTFCGSPPYAAPELFR---DQH-YVGVYVDIWALG
.|| | . ....| .||.|.|. .||||||| ||. |..   .  .|. ||||.   . . .....|||..  |.|||. .    |  . .  .|.| ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH-DKACDWWSLG

VLLYFMVTGTMPFRA---ETVAKLKKSILEGT--YTIP--QHVSEPCHRLIRGVLQPTPTERYG-----INYIMSNEWM
||.| | ||  ||..   .. ... | |..|.   |.|  | .|...  |||. |.  |  |.|     .. | ...|.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase NIM1.AA MELK 74-325 37 1.9e-73 250.33 In-house 1-254 (254) Show / Hide 
Range on Protein: 74-325
Range on HMM: 1-254/254
Sequence Identity: 37% (97 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPES
| .  |||.| |..|||  | || ..|||||.|| .| .   |.   |. .. .|.| .| .|| ..||  |. .||||  |||.|  |  . .|.| |.
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLPRVKT-EMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEET

KLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEM----LNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTM
. .| ||.||. ..|     ||||| ||....    .|. |||.   . ||..    |.| |||| |||||| . ..|.|   |.|..|.||| .. | .
RHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWM
||  . .  . | |. | |  |...|    .|.| .||  |. |  .  ..  .|.
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase NIM1.AA Pkinase_Tyr 74-216 30 2.8e-22 76.1 Pfam 1-156 (270) Show / Hide 
Range on Protein: 74-216
Range on HMM: 1-156/270
Sequence Identity: 30% (48 aa)

YRIRGEIGSGNFSQVKLGIHS----LTKEKVAIKILDKTKLDQKT--QRLLSREISSMEKL-HHPNIVRLYEVVE-TLSK--LHLVMEYAGGGELFGKIS
 ..  ..|.|.| .|..|.       || .||.|.| | . ...   .. . ||.. | .| ||||||||| |.        . .||||. .| |     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----EGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFG
.    ...|. ..   .  || ..  . .....||||| | |.  |.  .||..|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase NIM1.AA TyrKc 74-324 22 3.1e-17 56.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 74-324
Range on HMM: 1-280/280
Sequence Identity: 22% (64 aa)

YRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKL--HHPNIVRLYEVVETL-------SKLHLVMEYAGGGELFGKI-S
 .   ..|.|.| .| .|. .   ..||.| | . .     .. . ||.. | ||  ||||||||| |. .          | .||||. .| |   . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKG-------EMLNT-F--CGS--PPYA--APELFRDQHYVG
...||. ..   .  || .   . |....||||| | |. .... .||..||| |   . .       ..  .    .|    |.   ||| ...  .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-T

VYVDIWALGVLLYFMVTGTMPFRAE------TVAKLKKSILEG-TYTIPQH--------VSEPCHRLIRGVLQPTPTERYGINYIMSNEW
   |.|. ||... . |  ..   .      . . . . . .|    .|..         ..  .....   .  | .|   . |   ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
UBA_CAMKL NIM1.AA UBA_CAMKL 354-391 19 5.3e-05 16.35 In-house 1-41 (41) Show / Hide 
Range on Protein: 354-391
Range on HMM: 1-41/41
Sequence Identity: 19% (8 aa)

ENEVKSTLEHL--GITDEHIRNNQGRDAR-SSITGVYRIIL
. |.   ....  |.. |.|..    . .   ||. |...|
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL