Gene NuaK2 (Mouse)

NuaK2

Species: Mouse
Alias: NuaK2, 1200013B22Rik
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: NuaK

Sequence

Name Sequence Type Origin Length Description Download
NuaK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
NuaK2.AA Protein Sugen 631 None Fasta, JSON
NuaK2.NA RNA Sugen 3095 None Fasta, JSON

Protein domain

Protein domains of NuaK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NuaK2.AA NuaK 57-307 78 8.60000000001e-266 708.74 In-house 1-252 (252) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-252/252
Sequence Identity: 78% (197 aa)

YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLSERD
|||..|||||||||||.|.| |.||.||||||.|.||.||||..||||||||||||||||||.|.|||||..||||||||||.|.|||||||. .|.||.
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFD
|||||||||||.||||...|.||||||||||||.|.|.|||||||||.||..|||.||||||||||||||||.|| |||||.||||||||..|.||||||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

GQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWV
|.|.|.||||||.|||.||.||||||.||||.|||||.||||..|...||||
GHDFKHLVKQISQGAYYEPCKPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase NuaK2.AA CAMKL 57-307 44 3.9e-155 498.65 In-house 1-297 (297) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-297/297
Sequence Identity: 44% (135 aa)

YEFLETLGKGTYGKVKKARE-SS-GRLVAIKSIRKDKIKD-------------EQDLLHIRREIEIMSSLN---HPHIIAIHEVFENSSK------IVIV
|....|||||..|||| |.  .  |. |||| | |.||..             |.|. .|||||.||..||   ||.|| ..||.|....      |..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYASRGD--LYDYISERPR----LSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANG--NIKIADFGLSNLYHK-----GKFLQTFCGSPLY
|||.| |.  |.||| ....    ..|..||..|||||||..|||..||||||.|.|||||| ||  ||||.|||.||.| .     |..| |||||| |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEIVNG--KPYVGPEVDSWSLGVLLYILVHGTMPFDGQ--------DHKTLVKQISNGAYREPPK---PSDACGLIRWLLMVNPTRRATLEDVASHWW
..|||..|  ||| ||.|| ||.||.|| .| |..|||..        .. .| ..|  | |..|.    . |.  |||..|.|||..|.|.... .|.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

V
.
M
Kinase NuaK2.AA CAMK 62-307 30 9.20000000001e-138 446.83 In-house 1-425 (425) Show / Hide 
Range on Protein: 62-307
Range on HMM: 1-425/425
Sequence Identity: 30% (129 aa)

TLGKGTYGKVKKARES-SG------------RLVAIKSIRKDKIKD-------------------------EQDLLHIRREIEIMSS-------LNHPHI
|||.|..||||....  ..            . |||| | |.|.||                         ..|.  .|||||||..       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IAIHEVFE------------NSSK--------IVIVM---EYASRG----DLYDYISERPR---------------LSERDARHFFRQIVSALHYCHQNG
| ..||.|            . ||        ...||   ||.| |    ||.||| |...               ..||.||..||||.||.||||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKLENILLDAN-----------------GNIKIADFGLSNLYHK------------------------GKFLQTFCGSPLYAS-PEIVNG-----
|||||||.|||||| |                 .||||.|||..| . .                        |. ..||||.| |.. ||..||     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KPYVGPEVDSWSLGVLLYILVHGTMPFDGQ-------------DHKTLVKQISNGAYR-EPPKPSD------------------------AC
        |||.||..| ||.||.|||.. |..||.|              . . | ..| .| |. .||. |.                        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

GLIRWLLMVNPTRRATLEDVASHWWV
 |||..| |.|..|.|.|.. .| |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase NuaK2.AA MARK 57-307 50 9.90000000001e-132 432.76 In-house 1-262 (262) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-262/262
Sequence Identity: 50% (132 aa)

YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFE--NSSK-IVIVMEYASRGDLYDYISER--PR
|..| |.|.|.|.|||.|.   .|| |||| . | |. | | .  ..||||||..|.||.||  ..|.|  .... |...|||||.|.||||| ..   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANG--NIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILV
|.|..||..|||||||..|||...|||||.|.||||.|.||  ||||.|||.|.    |. | ||||.| |..|||...||| ||.|| |||||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

HGTMPFD--GQDHKTLVKQISNGAYREPPKP-SDACGLIRWLLMVNPTRRATLEDVASHWWV
.|. |||  .|| |.| |.| .| |. |..   ..  ||..||.||| .|.|.|.. .| |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase NuaK2.AA AMPK 57-307 50 5.2e-130 388.13 In-house 1-254 (254) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-254/254
Sequence Identity: 50% (128 aa)

YEFLETLGKGTYGKVKKAR-ESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVF-ENSSKIVIVMEYASRGDLYDYISERPRLSER
|   .|.|.||.|||| .  .  |  |||| . |.||||...   |.|||.|. ...|||||   ||  |  . | .||||.| |.|.|||  . ||.||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

DARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPF
.|. || ||.|.. |||...|||||||.||.|||.| ||||.||||||.. .|.|| | |||| ||.||.. ||.|.||||| || || || .. |. ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DGQDHKTLVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV
| ..  || | | || |  |   |. . .||. .| |.|. |.| .|.  | | 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase NuaK2.AA S_TKc 57-307 37 7.6e-106 358.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

YEFLETLGKGTYGKVKKARESS-GRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASR--GDLYDYISERPR---
||.|...|||..|||.|.|. . ||.|||| |.           ||||||.|... .||.|. ...||.. ... .||||..   |||.||| .|.|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGP-EVDSWSLGVLLYI
   ..| .||....||..|| |||..||.||||| ||||||   .|||.||||. ..       ||||.| | .||..      |. ..| ||.|..||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

LVHGTMPFDGQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVAS-------HWWV
.. |  ||.  ..... |.|          ...|. .|| .| ..|..| |  ..         | |.
MLCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NuaK2.AA AGC 57-307 24 1.3e-105 273.45 In-house 1-395 (395) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-395/395
Sequence Identity: 24% (100 aa)

YEFLETLGKGTYGKVKKARE-------SSGRLVAIKSIRKDK---IKDEQDLLHIRRE------------IEIMSSLN----------HPHIIA-IHEVF
.||| ..|||..|||  .|.       ..|.. |.| ..|..   ||..... |. .|             .|.. .|          || |.   |  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENSSK--IVIVMEYAS---------RG-DLYDYIS---ERPRLSERDARHFFRQ-------IVSALHYCHQ-NGIVHRD-LKLENILLDANGNIKIADFG
.. ..  . .||||..          | .|. ..     . |..|  ||... .       ||.||.| |. .||.||| ||.||||||..|.||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LS-------------------NLYHKGKFLQ----------------------------------TFCG--SPLYASPEIVNGKPYVGPEVDSWS--LGV
|.                   .  |..|. |                                  ||||  .| | .|||.      |...| ||  ||.
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-QKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGC

LLYILVHGTMPFDGQ----------DHKTLVKQISNG-----AYREPPKP------------SDACGLIRWLLMVNPTRRAT----------LEDVASHW
|.| .. |  || |.          ... . ..| ||        . | |            ..|  ||. || ..|..| .           |.. .| 
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

WV
| 
WF
Kinase NuaK2.AA QIK 57-307 44 4.6e-105 355.35 In-house 1-272 (272) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-272/272
Sequence Identity: 44% (122 aa)

YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPR-----
|.   |.||| .. || ||       ||||.| | .. ||..|  . ||..|| .|.|||||   .| |  . . ||.||.| |...||. .  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEV
               ..|..||  | ||.|| ||||. .||||||| ||||||.| ||||||||.||.. .|. |.|.|||| || ||.  || | ||.|
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DSWSLGVLLYILVHGTMPFDGQDHKTLVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV
| ||.||.||.|| | .||||.  ..| . .  | .| |.  |  |  |||  | |.|..| | . .  | | 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase NuaK2.AA Pkinase 57-307 34 3.4e-101 347.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLLHIR-REIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRG----DLYDYIS--ER
|......|.|..|.|.|... . .  ||.| |.|...|...|  |.| .||.|| .||||.|. ....||....| .||||.  |    ||.||||  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PRL--SERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNI----KIADFGLSNL--YHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSL
 ..  ||........||...| |||..||.|||||.||||.| ||.|    ||.||||. .  | ..  ..||||.| |..||...| .| ||.|| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYILVHGTMPFDGQ------DHKTLVKQISNGAYREP-PKP---------------------SDACGLIRWLLMVNPTRRATLEDVASHWWV
|..||... |  ||.|.      |.. ....|  . .... |..                     .... .|.|.| ..|..| | |..  | |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase NuaK2.AA TSSK 57-307 37 5.6e-95 312.16 In-house 1-289 (289) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-289/289
Sequence Identity: 37% (107 aa)

YEFLETLGKGTYGKVKKARESSGRLV-----------------AIKSIRKDKIKDEQDLLHIRREIEIMSS-LNHPHIIAIHEVFENSS-KIVIVMEYAS
|.. ...|.|.|.||..|.  . ..                  ||| | . | ...     . |||.||   |.||.|| ..| ||... || .|||||.
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

RGDLYDYISER------PRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGK------FLQTFCGSPLYASPEIV
.||| .|| .|      ..|.| .|| .|||.|||. |||  ..||||||.|||||| ..|||..||| ..   ...       ..|||||  ||.|||.
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

NGKPYVGPEVDSWSLGVLLYILVHGTMPFDG--QDHKTLVKQIS--NGAYRE--PPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV
 |.|| .  .| ||.|| |||.| |.||||   ...... .|..  . ....   .  |..|  ||| .|  .|..|........| |.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase NuaK2.AA BRSK 57-307 42 5.1e-82 278.79 In-house 1-254 (254) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-254/254
Sequence Identity: 42% (108 aa)

YEFLETLGKGTYGKVKK-ARESSGRLVAIKSIRKDKIK-DEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERPRLSER
|    |||||. |.||      .|. |||| | | |    |  |  . ||| ||   .|||.. ...|.||.     ..|. | | |.||  .. ||  .
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

DARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPF
 || |||||.||| .||   | ||||| || |||   ||||||||.  |  |.  | | |||| ||.||.. |  | |   | || || || |  | .||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DGQDHKTLVKQISNGAYREPP-KPSDACGLIRWLLMVNPTRRATLEDVASHWWV
|      |   . .|..  |.  . |.  | | .. |.| .| .|...  | |.
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase NuaK2.AA Ciliate-E2 57-307 25 4.1e-81 275.77 In-house 1-365 (365) Show / Hide 
Range on Protein: 57-307
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YEFLETLGKGTYGKVKKARE------------------------SSGRLVAIKSIRKDKIKDEQDLLHIRREIE----------IMSSLNHPHIIAIHEV
|.|.. .|.|..|.|.|..                           . ..|.|...|..|.     .|| |||.          |...||||.|| ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NSSKIVIVMEYASRGDLYDYISER-----------PRLSERDARHFFRQIVS---------------ALHYCHQNG-IVHRDLKLENILLDANGNI
|.  . ..| .||||.. |||.||| ..            ...|. ......||..               ||.|.|... |.|||.|.||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGLS----------------NLYHKGK-----------------FLQTFCGSPLYASPEIVNGKPYVG--------PEVDSWSLGVLLYILVHGTM
||.|||||                ..|   |                   .|.||.| | .|||.|||.| .         ..| |||||.||... |  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDGQDHKTLVKQISNGAYREPPK-------------------PSDACGLIRW----LLMVNPTRRAT-LEDVASHWWV
||         .|| .. .. |..                   . ..  ||.     .| ..|  | |  |..  | | 
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase NuaK2.AA Pkinase_Tyr 57-201 30 1.9e-34 117.31 Pfam 1-158 (270) Show / Hide 
Range on Protein: 57-201
Range on HMM: 1-158/270
Sequence Identity: 30% (49 aa)

YEFLETLGKGTYGKVKKARES-----SGRLVAIKSIRKDKIKDEQD--LLHIRREIEIMSSL-NHPHIIAIHEVFE-NSSK--IVIVMEYASRGDLYDYI
 .|...||.| .|.|.|..        .  ||.|.. |.   ....  .    ||..||..| .||.|.  . |    .    | |||||.  |||.|| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SE----RPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLS
 .    ...|.  |  .. .|| ... | ......||||   |.|.. |. .||.||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase NuaK2.AA TyrKc 57-305 24 2e-26 95.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 57-305
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSL--NHPHIIAIHEVFENS-------SKIVIVMEYASRGDLYDYI-S
 .....|| | .|.| |.. .  . ||.|....|.      .  ..||..||..|  .||.|.... |   .         . |||||.. ||| ||. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYHKG------KFLQTF----CG---SPL-YASPEIVNGKPYVG
 ||.|. .|  .|  || .   | |.....||||   |.|...|. .||.|||||   . .      |   .     .|    |.   .||  | . .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-T

PEVDSWSLGVLLY-ILVHGTMPFDG-----QDHKTLVKQISNGAYREPPKP-----------SDACGLIRWLLMVNPTRRATLEDVASHW
.. | || ||... |.  | .|  |      . . ..... .| ....|.                 ....  . .|  | | ... . .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF