Gene PAK5 (Mouse)
PAK5
Sequence
Protein domains of PAK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PBD | PAK5.AA | PBD | 10-67 | 31 | 2.3e-21 | 77.07 | Pfam | 1-60 (60) | Show / Hide |
Range on Protein: 10-67 Range on HMM: 1-60/60 Sequence Identity: 31% (19 aa) EISGP-SNFEHRVHTGFDPQEQKFTGLPQQWHSLLADT-ANRPKPMVDPSCITPIQLAPM .||.| .||.|..| |.|.|...|||.|..| .|| .. .|.....|....... .. MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ |
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| PBD | PAK5.AA | PBD | 11-46 | 52 | 2.2e-15 | 58.36 | SMART | 1-38 (38) | Show / Hide |
Range on Protein: 11-46 Range on HMM: 1-38/38 Sequence Identity: 52% (20 aa) ISGPS-NFEHRVHTG-FDPQEQKFTGLPQQWHSLLADT || |. ||.|.|| | .|.|...||||| || .|| . ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC |
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| Kinase | PAK5.AA | PAKB | 449-700 | 87 | 1.1e-228 | 766.0 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 449-700 Range on HMM: 1-252/252 Sequence Identity: 87% (221 aa) LDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATV |||..|||||||||||||||||||.||||||||||||||||||||||||||||.|.|.|.||.||||||||||||||.|||||||||||||||||||||| LDNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHTRMNEEQIATV CLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPP |..||.||.|||.||||||||||||||||.|||.||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||| CRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPP LQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL ||||.||||..|||.|..||||..||.||| ||||.|.||.|||||| |||| LQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL |
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| Kinase | PAK5.AA | STE20 | 449-700 | 46 | 1.3e-150 | 506.64 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 449-700 Range on HMM: 1-288/288 Sequence Identity: 46% (133 aa) LDNFIKIGEGSTGIVCIATEKHTGKQ----VAVKKMDLRKQ----QRRELLFNEVVIMRDYHHDNVVDMYNSYLVG----DELWVVMEFLEGGALTDIVT ... |||.||.| |. |..|.||.. ||.|||.|.|. ...|....|..||....| |.| .|.|||.. ||||.|||...|| ||||.. YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK HT----------RMNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSK-----EVPKRKSLVGTPYWMAPEVISR---- |. .|||||||..| ||..|.|||....||||||.| ||||.||..||.|||.|||..| . .||...||||||||||||.. HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP -LPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIR--DSLPPRVKD--LHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL .|.. .|||||||. |||..||||||...|..|| .| . ||. || || |. .. |.|..|...|..|.||..|| |||. DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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| Kinase | PAK5.AA | PAKA | 450-700 | 52 | 3.2e-134 | 452.2 | In-house | 2-260 (260) | Show / Hide |
Range on Protein: 450-700 Range on HMM: 2-260/260 Sequence Identity: 52% (135 aa) DNFIKIGEGSTGIVCIATEKHTGKQ--VAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTR------MN ... |||.|..| | .||...|... ||.|.|.. .| . ||. || .|....|.|.|. . |||| ||||||||..||| |||..|... |. KFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYMD EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEP |.||| || .|..|...|....|||||||| ||| .||..|. ||||||| ..| ||.. ||||||||||||.| |. |||||||||.||||.||| EGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGEP PYFNEPPLQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL || ||||| || | | || .|.|. .. |||. | .. .||.||||| |||| PYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL |
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| Kinase | PAK5.AA | STE | 449-700 | 29 | 9.69999999999e-118 | 397.46 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 449-700
Range on HMM: 1-359/359
Sequence Identity: 29% (109 aa)
LDNFIKIGEGSTGIVCIATEKH---------------TGKQVAVKKMDLRKQ-----------------QRRELLFNEVVIMRDYH--HDNVVDMYNSYL
... |||.|..| |. | .. ||. .|.|.|.|... . .. . .|. ||.... |.|.| | .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF
VG-------DELWVVMEFLEGGALTDIVTH---------------TRMNEEQIATVCLSVLKA-LSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCA
.. ||||..||...|| |.||. | .|..|.|||..| ..||. |.|||....||||||.. ||| .||.|||.|.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG
QVSKEVP----------------KRKSLVGTPYWMAPEVISR------LPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDS-----------
|...... ||...|||| |||||||.. .|.| .||||||...|||..|.||.....|..|| .| ..
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC
----LPPRVKD-----------------LHKVSSMLRGFLDLMLVREPSQRATAQELLG--HPFL
||. .| ||.|. .. |... |...|..|.||..|| |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
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| Kinase | PAK5.AA | S_TKc | 449-700 | 29 | 8.3e-93 | 315.55 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 449-700 Range on HMM: 1-231/231 Sequence Identity: 29% (80 aa) LDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEG--GALTDIVTHTR------- . |||.|. | |. ...|.||..||.|... | . .|. |.. ||.|.| .| .. |.|..|||...| | | |. . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP MNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGT-EVDIWSLGIMVIEMID ..| ... .. ...|| |.|..|.||||.| . |||.. .||..|||...|. ....|||..|||||. .||. ..|.||.|....||. FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC GEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLG-------HPFL |.||. . . ...|. |. .. |.. .|...|..| || |.| ||.. GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | PAK5.AA | Pkinase | 449-700 | 29 | 7.3e-85 | 293.03 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 449-700 Range on HMM: 1-293/293 Sequence Identity: 29% (87 aa) LDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRREL--LFN--EVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGG----ALTDIVT---H . |||.|| | |.....| |||.||||....|.. .. ... |. ||. .|.|.| .| .. .|....|||..||| | |... | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH TRM--NEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRI----KLSDFGFCAQV-SKEVPKRKSLVGTPYWMAPEVIS-RLPYGTEVDIWSL ... |... ... .|..| |.|..|.||||.|.. ||. ..| | |..|||...|. . ....|||..|||||| . .||..||.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GIMVIEMIDGEPPYFNE------PPLQAMRRIRDSLPPRVKDLH------------------KVSSMLRGFLDLMLVREPSQRATAQELLGHPFL |....||. |.||. .. ..| ..||.. ... . ..|. .. |.. .| . |..| ||...| ||.. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | PAK5.AA | YSK | 454-700 | 37 | 2.5e-79 | 238.42 | In-house | 6-257 (257) | Show / Hide |
Range on Protein: 454-700 Range on HMM: 6-257/257 Sequence Identity: 37% (96 aa) KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRR-ELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTH---TRMNEEQIATVC .|| || | | . ...|.. ||.| || . |.. |. . . .. | ||| . ||..||.. || . | . |..||.. CIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYIAIIL LSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISR--LPYGTEVDIWSLGIMVIEMIDGEPPYFNEP .||.|.||| . .||||||. .||. .| .|| ||| .|. . || |||||||||||| | . .||||||| .|| ||||| REILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYH PLQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL |. .| .| . ||. .. .. | |. | .. |. .|.|| .|.||| | | PMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI |
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| Kinase | PAK5.AA | MST | 450-700 | 41 | 1.5e-77 | 246.09 | In-house | 2-254 (254) | Show / Hide |
Range on Protein: 450-700 Range on HMM: 2-254/254 Sequence Identity: 41% (105 aa) DNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYL--VGDELWVVMEFLEGGALTDIVTHTR--MNEEQI | |.|.|| | | |. | ||| ||.|.. . . .| || . ...| | ||. ..| |||. ..| . ||. |. ||.|| DIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQI ATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFN |... ..|. | |||. ||||||. ||| .| ||.||| .| . || ...||||||||||| . | . .||||||| ||| |.|||.. ACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSD EPPLQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL | || | . || || .. |. . |. |...|.||.|| .|| ||| IHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI |
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| Kinase | PAK5.AA | KHS | 450-700 | 40 | 1.1e-73 | 247.25 | In-house | 2-258 (258) | Show / Hide |
Range on Protein: 450-700 Range on HMM: 2-258/258 Sequence Identity: 40% (103 aa) DNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHT-RMNEEQIATV . ..| | | | | ...... .||| . . .. ... |...|.| .| |.| . ||| | ||..||. ||.| || | ..| ||| | ELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV CLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVIS---RLPYGTEVDIWSLGIMVIEMIDGEPPYFN | .|..| |||..| .||||| ||||..| .|| ||| ||.. . |||| .|||||||||| . . |. |||..|| ||. . || |. CRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPMFD EPPLQAMRRIRDS--LPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL |..|. . | ||..|| || |.. |. . |...| .| ||. || |||. LHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV |
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| Kinase | PAK5.AA | CAMK | 454-700 | 18 | 5.7e-70 | 224.43 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 454-700
Range on HMM: 1-425/425
Sequence Identity: 18% (78 aa)
KIGEGSTGIVCIATEKHTG------------KQVAVKKMDLRKQQR----------------------------RELLFNEVVIMRD-------YHHDNV
..|.|| |.| ...|.|. ..||.| .| .| . |. ...|. ||. .| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VDMYNSYL------------VGDE--------LWVVM---EFLEGG----A-LTDIVTH---------------TRMNEEQIATVCLSVLKALSYLHNQG
. .| | . .. || |. .|| . || | |..|.. ... .. |. |.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VIHRDIKSDSILLTSD-----------------GRIKLSDFGFCAQVSK-----------------------EVPKRKSLVGTPYWMA-PEVISR-----
..|||.| . |||... . ||..|||| ... . | .| | .|||. || |||...
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------LPYGTEVDIWSLGIMVIEMIDGEPPYFNEP----------------PLQAMRRIRDS-LPPRVKD---------LHKVSSM--------LR
.|| ..|.||.|.. | |.||. . .. .. . . || ... ...| .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
GFLDLMLVREPSQRATAQELLGHPFL
.. ||...|..|.|... | ||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | PAK5.AA | SLK | 451-700 | 35 | 3.5e-68 | 229.09 | In-house | 2-259 (259) | Show / Hide |
Range on Protein: 451-700 Range on HMM: 2-259/259 Sequence Identity: 35% (92 aa) NFI-KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVT--HTRMNEEQIAT . | .|.| | | | .| ... | | ...... | . |. |. . .| |.|..|..| . ..||...|| .|||. |. . . |.||. EIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQY VCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVI-----SRLPYGTEVDIWSLGIMVIEMIDGEPP || .. || .||.. |||||.| ||.| || ..| ||| |. ... || . .||||||||||. || .||||||| .||| ..||| VCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEPP YFNEPPLQAMRRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL . . |. . .|. | ||... . |. . || ||..| .| |...|. |... HHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV |
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| Kinase | PAK5.AA | STE11 | 454-700 | 31 | 9e-63 | 214.86 | In-house | 6-303 (303) | Show / Hide |
Range on Protein: 454-700 Range on HMM: 6-303/303 Sequence Identity: 31% (93 aa) KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQR---------RE-----LLFNEVVIMRDYHHDNVVDMYNSYLV---GDELWVVMEFLEGGALTDIVT .||.|. | | . ..||. .|||.. .... .. .. |. .|. .| | | .| . | |.. . ||. .|| | .. IIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLR HTR----MNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGR-IKLSDFGFCAQVSKEVPKRKS----------LVGTPY--------WMAPE | . ..| | .|..|.||| .|.|||||| . ||| ||| .||.||| . ..... .. .. . |||| ||||| HKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPE VISRLP---YGTEVDIWSLGIMVIEMIDGEPPYFNEP--PLQAMRRIRDSLPPRVKDLHKVS------SMLRGFLDLMLVREPSQRATAQELLGHPFL ||.. . ||. .|||||| ||||. | ||. | . .|| .| . | ..| .| ||.. ....|. |.||..|| |||. VIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI |
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| Kinase | PAK5.AA | Pkinase_Tyr | 449-657 | 27 | 5.8e-25 | 85.17 | Pfam | 1-231 (270) | Show / Hide |
Range on Protein: 449-657
Range on HMM: 1-231/270
Sequence Identity: 27% (64 aa)
LDNFIKIGEGSTGIVCIATEK----HTGKQVAVKKM--DLRKQQ--RRELLFNEVVIMRDY-HHDNVVDMYNSYL-VGDE--LWVVMEFLEGGALTDIVT
. |.|||. | |. .| | |. .||||.. . ..| |.... |. ||. . ||.|.| .| . |. ...|||. ..| | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR
HT-----RMNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQV-SKEVP--KRKSLVGTPYWMAPEVISRLPYGTEVDIWS
. . ... |. . |...||.... ||||. .|.|... .| .||| . . ... ||.. |||||.|. . |. |.||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS
LGIMVIEMID-GEPP-YFNEPPLQAMRRI-RD
|. |.. || | | . .. . ...| .|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED
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| Kinase | PAK5.AA | TyrKc | 449-700 | 24 | 2e-19 | 71.78 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 449-700 Range on HMM: 1-280/280 Sequence Identity: 24% (70 aa) LDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDY--HHDNVVDMYNSYLVG-------DELWVVMEFLEGGALTDIVTHTR . |.||| |.|. .| | |||||.. . || . .| ||. . ||.|.| .| . . . |..|||. ..|.| | .| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR --MNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKE-------VPKRKSL-VGTP-----YWMAPEVISRLPYGTEV . .. |. . . .||| ...||||. .|.......| |||| . . . .||. |. |||||.| . |. PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS DIWSLGIMVIEMI-DGEPPYFN-----EPPLQAMRRIRDS-LPPRVKD------LHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFL |.|| |.. |. .|..|| . .. ........ .|. .. . . | . ..|..| | .|. | .. DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF |
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