Gene PHKg2 (Mouse)

PHKg2

Species: Mouse
Alias: PHKg2, Phkg2
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: CAMK
Family: PHK

Sequence

Name Sequence Type Origin Length Description Download
PHKg2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 268 Kinase domain by global Sugen HMM Fasta, JSON
PHKg2.AA Protein Sugen 406 None Fasta, JSON
PHKg2.NA RNA Sugen 1644 None Fasta, JSON

Protein domain

Protein domains of PHKg2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PHKg2.AA PHK 24-291 70 1.1e-237 795.95 In-house 1-273 (273) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-273/273
Sequence Identity: 70% (193 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVS-AERLSLEQLEEVRDATRREMHILRQVA---GHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
|.||.|.||||||.||||.|..||.||||||.... .|..| ...|..|.|||.|.||||||.   |||.||.|.|.||..||||||||.|..|||||||
YEPKEILGRGVSSTVRRCIHKNTGQEFAVKIIDITGTEHQSENEAEHMREATRQEIHILRQVMEGEGHPNIIQLHDFYETNSFMFLVFDMMPRGELFDYL

TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMD-ETHPGYGKEVDLWA
||||.||||.||.|||.|.|.|...||.|||||||||||||.||||.|..|||||.|.|..|||||||||||||||||..||||. |.|||||.|||.||
TEKVTLSEKKTRRIMRQLFEGVCYMHAHNIVHRDLKPENILCDDNMNIKISDFGFACQLQEGEKLRELCGTPGYLAPEMIKCSMYLENHPGYGQEVDMWA

CGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQHPFF
||||..|||||.||||||.|..||||||||.|||.||||||.|.|.||||||.|||||..|.|||..||||||
CGVIMYTLLAGCPPFWHRKQMMMLRMIMEGKYQFGSPEWDDISDTPKDLISKCLQVDPQQRITAEECLQHPFF
Kinase PHKg2.AA CAMK 29-291 28 1e-124 404.02 In-house 1-425 (425) Show / Hide 
Range on Protein: 29-291
Range on HMM: 1-425/425
Sequence Identity: 28% (119 aa)

IIGRGVSSVVRRCVHRATG------------DEFAVKIMEVSAERLS----------LEQL----------EEVRDATRREMHILRQVAG------HPHI
..|||  ..|..|.|. |.             ..|.||.. .  . .          ..            .. |.  |||..|.... |      ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITLIDSYESSSF-------------------MFLVF---DLMRKGEL----FDYLTEK---------------VALSEKETRSIMRSLLEAVSFLHANNI
| |.. ||....                   |..|.   ...  |||    |||..|.                 ..|.|.| ..| ...|| ..| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENILLDDNM-----------------QIRLSDFGFSCHLEA------------------------GEKLRELCGTPGYLA-PEIL----KCSM
|||||||||||||||.                 .| ..||||.....                         |.|... ||||.| | ||.|    .|.|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----DETHPGYGKEVDLWACGVILFTLLAGSPPFWHR-------------RQILMLRMIMEGQYQFTSPE------------WDDRSNT--------VKD
    ||..|.||...| |.|||||...| | |||..               .  ....||.|.|.| .|.            ||| |.         .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKLLQVDPEARLTAEQALQHPFF
||.|.|||||| |.|.||.|.||..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PHKg2.AA CAMK1 24-291 38 4.6e-120 350.72 In-house 1-276 (276) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-276/276
Sequence Identity: 38% (108 aa)

YDPKDIIGRGVSSVVRRCVHRAT---GDEFAVKIME-VSAERLSLEQLEEVRDATRREMHILRQV--AGHPHIITLIDSYESSSFMFLVFDLMRKGELFD
|  ...||||  |.|..|.|. |   |...|.|...  ..   . .|  . ..| ..|  |...|    ||.|| ... ||| ..  || .|.  |||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ--K-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFD

YLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN---MQIR--LSDFGFSCHLEAGE-KLRELCGTPGYLAPEILKC-SMDETHPGY
   ||   .||. | ||. .|.|| ..|...||||||||||.|. |.   ..|.  ..||| |  .. .| ..   |||||| |||.|.| .      .|
RIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK----DKPY

GKEVDLWACGVILFTLLAGSPPFWHRR-QILMLRMIMEGQYQFTSPEWDDRSNT-VKDLISKLLQVDPEARLTAEQALQHPFF
.|..|.| .|||...|| | |||.  . .  ....|....| | ||.||. |.  .||.|...| |||. |.|.||.|.||..
DKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase PHKg2.AA Pkinase 24-291 32 3.6e-112 383.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-293/293
Sequence Identity: 32% (98 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKG----ELFDYL
|  . .||.| ...|..|.|. ||...||||.... |. . .|    .    .| .|.. . .||.|..|.|..|... . .|......|    .||||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

T--EKVAL--SEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQI----RLSDFGFSCH--LEAGEKLRELCGTPGYLAPEILKCSMDETHPG
.  .. ..  ||.| ...|. .|... ..|...|.||||||||||.|.|..|    ...|||....  .  .. .  .||||.|.|||...     ....
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQY

YGKEVDLWACGVILFTLLAGSPPFWHR------RQILMLRMIMEGQYQFTSPEWDDRS-----------------NTVKDLISKLLQVDPEARLTAEQAL
||..|| |.||.||. .| | |||...      .|. |...||.... | .|.|...|                  . ||.|...|..||. |.||||.|
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

QHPFF
|||.|
QHPWF
Kinase PHKg2.AA S_TKc 24-291 33 3.8e-106 359.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-231/231
Sequence Identity: 33% (96 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRK--GELFDYLTE
|.  ..||.|  ..|..|.|. || ..|.||.                . .|||. ||..  .||.|..|.|.... .....|....    |.||||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

KVA------LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGK-EV
.        ..| ..|..|. ...|. ..| ..|.||||||||||||.  .| ..|||....|      . .|||| |.|||.|         |||| ..
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKCKC

DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQ-------HPFF
| |.||.||. .|.| |||.   . .|...|.              |  .||.|.|.||.||| |.|| .|||       ||.|
DWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PHKg2.AA Ciliate-E2a 24-291 35 1.3e-88 260.96 In-house 1-275 (275) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-275/275
Sequence Identity: 35% (100 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKV
|. ...|| |   .|.   |. ||..||.|. .  . . . .. |..     .|  |.||.  ||.|| |.. ||. .  .||...   |||.|.. .. 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYF----MNEINIMRQL-DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCK

ALSEK--ETRSIMRSLL-EAVSFLHANNIVHRDLKPENILLD---DN----MQIRLSDFGFSCHL--EAGEKLRELCGTPGYLAPEILKCSMDE-THPGY
 . |.  | ..||. || .... .| .||.||||||||||..    |     .| ..|||..       ....   ||||||.|||.|. . .. .|. |
RFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLN-NKEVLKHKQY

GKEVDLWACGVILFTLLAGSPPFWH--RRQILMLRMIMEGQYQFTSPE-WDDRSNTVKDLISKLLQVDPEARLTAEQALQHPFF
.. .|.| ||||...|| |.|||     ..|  | .. . ...| .|| | . |.  |||..|.|..||. |.||.|||.||.|
DTKCDMWSCGVIFYILLCGKPPFKGKTYNEI--LQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase PHKg2.AA CAMKL 24-291 33 2e-88 282.27 In-house 1-297 (297) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-297/297
Sequence Identity: 33% (103 aa)

YDPKDIIGRGVSSVVRRCVH-RATGDEFAVKIME--VSAERLSLEQL------EEVRDATRREMHILRQV-AG-HPHIITLIDSYESSSF------MFLV
|.  . .|.|  ..|. ..| | || . |.||..     ..   ..       | .    |||..|....  | ||.|| | . .| ...      ..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

FDLMRKGE--LFDYLTEK----VALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNM--QIRLSDFGFSCHLEA-----GEKLRELCGTPGY
  .   ||  ||||. ..      ..|.|.| . | ...||...| ..|||||.||||||||.|.  .| ..||||| . .      |.||.. ||.| |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

LAPEILKCSMDET-HPGYGKEVDLWACGVILFTLLAGSPPFWHR--------RQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQ
 ||||..     .  | .|..|| |.|||||.... |  ||            . .....||.| |..  | | . |  ..|||.|.|||.|| | |..|
MAPEIFQG----NNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

ALQHPFF
 ..||..
IMNHPWM
Kinase PHKg2.AA CDPK 24-291 38 9.5e-86 262.98 In-house 1-271 (271) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-271/271
Sequence Identity: 38% (111 aa)

YDPKDIIGRGVSSVVRRCVHR-ATGDEF-AVKIMEVS----AERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFD--LMRKGEL
|. |...|.|  ..||...|. .|..|  |.|| . |    .|           .   .|. ||.|   ||.|| .   |. . . ..|.   .   |||
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ---------QQQFFNEIEILKQL-DHPNIIKIYEFYQDEKNYYIVMETEYCTGGEL

FDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLD---DNM----QIRLSDFGFSCHLEA-----GEKLRELCGTPGYLAPEILKCSM
||| .||  ..|||...||| .| ||.  | ||||||||||||||.|   |.     .| . |.| |.  .      ..|... |||| |.|||.|. . 
FDYIIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKY

DETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQHPFF
.|       ..|.| |||||..|| |.|||. . .   . ....|.|.|  ||||. |.  ||||.|.|..||. |..|.|||||| |
NE-------KCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase PHKg2.AA RSK 26-291 33 2.4e-83 283.23 In-house 1-278 (278) Show / Hide 
Range on Protein: 26-291
Range on HMM: 1-278/278
Sequence Identity: 33% (94 aa)

PKDI--IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKV
 |.   .| |  ...|.|.|..|| ..|.|. . .  . .   ..     |..|  ||  . .|| |.|| ....  .  .|. ...| ||||. | ...
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRH----TMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEK

A---LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDD---NMQIRLSDFGFSCH--LEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVD
    .||.| . .|. .  ||..||   |.||||||||||.||   .  |.|.||||..   .. ....   |.|  |.|||.||        |..| .|
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQGGHDKACD

LWACGVILFTLLAGSPPFWH---RRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLT-----AEQALQHPFF
.|  ||.....|.| ||| .     .   .. |..|.. .|.|.|.  |.. ||||.|.|..||. ||.     ||. .|||.|
WWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PHKg2.AA CAMK-Unique 24-291 25 1.3e-82 272.49 In-house 1-363 (363) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-363/363
Sequence Identity: 25% (94 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEV-SAERLSLEQ-----------LEEVRDATRREMHILRQVAGHPHIITLIDS----YESSS------
|.   ||| |  ..|..|  |.||...|.|. .   ... .. |           .      ..||  |.. | .||.|| | |     .. .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMV-DHPNIIKLYDWNNPIFCDRKYPLCDL

---------FMFLVFDLMRKGELFDYLTE--------------------KVALSE--KETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQ----
          |..| ..  .|.|||.. .                    .  .||   .|..||..||.||...| ..|||||||.|||..  . .    
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

------------IRLSDFGFSCHLEAGEKLR---ELCGTPGYLAPEILKC------SMDET--HPGYGKEV----DLWACGVILFTLLAGSPPFWHRRQI
            | |.||| .||..  ..     . |||| |.|||| .|      . ||.   ..|.  .    |.|..|||....| |.||| .    
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------LMLRMIMEGQY-QFTSPEWDD---RSNTVKDLISKLLQVDPEARLTAEQALQHPFF
          .. |. |.|  | .. |..    |.  ||.. ....|||  |..|...|.|...
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase PHKg2.AA Ciliate-E2 24-291 26 4.1e-79 269.14 In-house 1-365 (365) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-365/365
Sequence Identity: 26% (102 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFA----------------VKIMEVSAERLS---LEQLEEVRDATR---------REMHILRQVAGHPHIITLID
|.   .||.|  ..|..| .. .. .||                |||...  ....   .||.. . .  |          |. ||.|.  ||.|| ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQL-NHPNIIKMYE

SYE--SSSFMFLVFDLMRKGELFDYLTEK-----------VALSEKETRSIMRSLLE---------------AVSFLHANN-IVHRDLKPENILLDDNMQ
...  . . ..||...   |.||||. ..             ..||| . ||. .|.               |. .|| .| |.|||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRLSDFGF--SCHLE---------AGEKLREL----------------------CGTPGYLAPEILK-CSMD--ETHPGYGKEVDLWACGVILFTLLAGS
| ..|||.   .. .         .....                         ||||||.|||||.  . |  ... ||....|.|..||||. .| | 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPFWHRRQILMLRMIMEGQYQFTSPE--------------WDDRSNTVKDLISK----LLQVDPEARLT-AEQALQHPFF
|||        .. |......| .||              |.. |. .||||.|    .||.||| |.| .||.|.||.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase PHKg2.AA RSK 24-291 33 9.5e-76 257.97 In-house 1-271 (271) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-271/271
Sequence Identity: 33% (94 aa)

YDPKDIIGRGVSS---VVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
|. .  ||.|  |   |...|.|..|....|.|| . ..   .        . .  |  ||| .  || |..| .....    ... |.|| |.||| | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR------VCWEEERIILRYG-HHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLL

EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDN----MQIRLSDFGFSCHLEAGEK-LRELCGTPGYLAPEILKCSMDETHPGYGKEVD
 .. .||.| . .|. .. |. .||   ||||||||||||.||       |.. ||||.  | . .. |   |.|  |.|||.||        |... .|
KQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLK------RQGHDQACD

LWACGVILFTLLAGSPPFWHR---RQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTA-----EQALQHPFF
 |  ||.... |.| .|| ..   .   ..  | .|.. .|.. ||  | . |||....| .||. ||.|     ||..|||.|
WWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase PHKg2.AA TyrKc 24-291 19 3.6e-13 -9.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-291
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQV-AGHPHIITLIDSYESS-------SFMFLVFDLMRKGEL
   ....|.|   .|.... .    . ||| .  .|           | . .||. |....   ||.|. |.    ..         ...|. .| .| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

FDYLTEKVA-LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEAG-------EKLRELC--GTPG-----YLAPEILK
 ||| ..   |. |.  |..    .  ..|| .|..||||   |.|...| ... |||| |  .. .       .  |     |. .      .||| . 
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

CSMDETHPGYGKEVDLWACGVILFTLLA-GSPPFWH-----RRQILMLRMIMEGQYQFTSPE------WDDRSNTVKDLISKLLQVDPEARLTAEQALQH
      .  .  . | |. || .. ..  | .| .         . ... ...| .    |.          .   . ....  . ||| | | ..   |
-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--H

PFF
 .|
ECF
Kinase PHKg2.AA Pkinase_Tyr 76-173 28 5.2e-08 27.74 Pfam 52-156 (270) Show / Hide 
Range on Protein: 76-173
Range on HMM: 52-156/270
Sequence Identity: 28% (30 aa)

REMHILRQVAGHPHIITLIDSYE-SSSF--MFLVFDLMRKGELFDYLTE----KVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIR
||. |..|   ||.|. |.      .    ...|. .| .| | ||| .    | .|. |.  .. .   .. ..|...|..||||   |.|...|....
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVK

LSDFG
 .|||
ICDFG