Gene TESK2 (Mouse)

TESK2

Species: Mouse
Alias: TESK2
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TKL
Family: LISK
Subfamily: TESK

Sequence

Name Sequence Type Origin Length Description Download
TESK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 251 Kinase domain by global Sugen HMM Fasta, JSON
TESK2.AA Protein Sugen 570 None Fasta, JSON
TESK2.NA RNA Sugen 3032 None Fasta, JSON

Protein domain

Protein domains of TESK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TESK2.AA TESK 62-311 63 4.6e-205 654.18 In-house 1-292 (292) Show / Hide 
Range on Protein: 62-311
Range on HMM: 1-292/292
Sequence Identity: 63% (186 aa)

EKIGSGFFSEVFKVRHRASGQVMALKMNT---LSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD-SDLYLPWTVRVKLA
|||||||||||.|||||||||||.||||.   ...||.|.|.|.||||.|.|||||||||||||||||||||||||.|.|||||. |.|.|.||....||
EKIGSGFFSEVYKVRHRASGQVMVLKMNKQKIWRANRHNMLREVQLMNKLQHPNILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLA

YDIAVGLSYLHFKGIFHRDLTSKNCLIK-RDENGYSAVVADFGLA----------------------------------EKIPDASIGREK--LAVVGSP
||||.|.||||.||.|||||||||||.. ||.|.|.|||.|||||                                  ||||.......|  .||||||
YDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLGCMPDPPPNSPRTPESPEPDIIDAPNGGPMLEKIPVYCMDSRKEKMAVVGSP

FWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVG-DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKE
.||||||||.|.|.|||||||.||.||||||||||||||.||||.|||||.||..|.. |||..||||.|.|||||||.||.|.||.|.|. 
YWMAPEVLRGEWYDEKADVFSFGIVLCEIIARIQADPDYMPRTEKFGLDYQAFKEMCPMDCPEPFLQLAFHCCNMDPKDRPVFHEITKHLEW
Kinase TESK2.AA LISK 63-309 45 4.4e-168 550.39 In-house 1-296 (296) Show / Hide 
Range on Protein: 63-309
Range on HMM: 1-296/296
Sequence Identity: 45% (136 aa)

KIGSGFFSEVFKVRHRASGQVMALKMNT-------LSSNRANLLKEMQLMNRLSHPNILRFMGVCVH-QGQLHALTEYINSGNLEQLLD-SDL---YLPW
.||.|||..|.|..||..|||||.||..       . ... ..|.|.|.|..|.||||..|||||.| .||||..||||| |.|.|.|. .|.    |||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

TVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK-RDENGYSAVVADFGLA------------------------------EKIPDASIGREK--LAVV
..|||.|.||| |.||||...|.||||.|||||.. .|.|.....|.|||.|                              .|||.......|  ....
PQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTIC

GSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTE--NFGLDYDAFQ-NMVGD-CPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
|.|.|||||.|... |.|..||||.||.|||||.|..|||||.|||.  .|||||..|.  ...| ||..||.|.|.||..||| ||||.|| ..|
GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase TESK2.AA TKL 64-309 27 3.4e-82 279.36 In-house 1-364 (364) Show / Hide 
Range on Protein: 64-309
Range on HMM: 1-364/364
Sequence Identity: 27% (101 aa)

IGSGFFSEVFKVRHRA--------SGQVMALKMNTLSS-----------------------------NRANLLKEMQLMNRLSHPNILRFMG--------
||||.|.||.| ..|         .|...| |.    .                             .|  . .|. .|.||.||||..|||        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-VCVH----QGQLHALTEYINSGN-LEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHF--------KGIFHRDLTSKNCLIKRDENGYS-----------A
 ||.|    .|||.  .||.  |. |..|.       | .|...|.||| |..|||         ..| ||||.|||.|.... . .|           .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

VVADFGLAE-KIPDASIGREKLA----------------VVGSPFWMAPEVLRDE----------------PYNEKADVFSYGIILCEIIARIQADPDYL
 ..||||.  . .. .  . . .                ..|.| ||||||||..                .|.||.||.|.||.|.||..| .   || 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

PRTENFGLDYDAFQNMVGD----------------------CPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
.... |. ...... ||.|                      || .. .|   |...||. ||||.|| |.|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase TESK2.AA LISK-DD1 108-309 35 3.6e-69 236.12 In-house 54-290 (290) Show / Hide 
Range on Protein: 108-309
Range on HMM: 54-290/290
Sequence Identity: 35% (84 aa)

LSHPNILRFMGVCVH-------------QGQLHALTEYINSGNLEQLLDS-------------DLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKN
..|||| .| |.|.|              . |. .||.|. |.| ..| .             .  .||. |||.|.||| . .||| |.| |||| |||
IRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWYLKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKN

CLIKRDEN---GYSAVVADFGLAEKIPDASIGREK--LAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRT--ENFGLDYDAFQ
 |.  |||    . . | |||.| ..   . ....  .  .|.. ||||||. .. |.. .||||.|. | |.| |   |.....|.    |..|...|.
ILV--DENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTICGTDNWMAPEVILGMSYDWSCDVFSFGMVLLELITRKKPDKRMWQRSPMNCFDIDQEEFR

N-MV-GD--CPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
.  . .|  ||..|. |...||. ||. |||| ||  ||
QQKIPKDNDCPREFMDLCMWCCKYDPNNRPSFKEIVQTL
Kinase TESK2.AA TKL-Unique 60-250 31 1.5e-49 170.92 In-house 1-222 (290) Show / Hide 
Range on Protein: 60-250
Range on HMM: 1-222/290
Sequence Identity: 31% (71 aa)

TREKIGSGFFSEVFKVRH-RASGQVMALKMNTLSSNR--ANLLKEMQLMNRLS-HPNILRFMGVCV----HQGQLHALTEYINSGNLEQLLD--------
  .|||.| ...|.|. . . .  .  .. | .|||.   .. .|  .|..|  ||||...||.|.    .....   .||.. |.|  .|.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

--SDLYLPWTVRVKLAYDIAVGLSYLHFKG--IFHRDLTSKNCLIKRD--ENGYSAVVADFGLAEKIP--DASIGREK-----LAVVGSPFWMAPEVLRD
  . . |.. .|||.| ||| |. |||...  | ||||.|.| |. ..  .. ... ..||||.      .... .|.       ..||..||||||||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EPYNEKADVFSYGIILCEII
  . |.||.||.|.||.| ||.
NFCQYSEKSDVYSFGIVLWEIA
Kinase TESK2.AA Dicty4 60-249 37 1e-44 147.19 In-house 3-210 (277) Show / Hide 
Range on Protein: 60-249
Range on HMM: 3-210/277
Sequence Identity: 37% (79 aa)

TREKIGSGFFSEVFKVRHRASGQVMALKMN-----TLSSNRAN-LLKEMQLMNRLSHPNILRFMGVCV----HQGQLHALTEYINSGNLEQLLDS-----
. ..||.| |.||.| . |  |.  | |.      ....|. | ..||  .|  ..||||. ||| |     | | .   |||  .|||. || .     
IEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

--DLYLPWTVRVK---LAYDIAVGLSYLHFKG--IFHRDLTSKNCLIKRDENGYSAVVADFGLAE-KIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEK
     |.|. . .   .| |.| |. .||     | |||| | | |.  |.| . . |.||||.  . .. . .    ...|.| ||||||.. .|||||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV--DKN-WRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEK

ADVFSYGIILCEI
|||.|.||.| ||
ADVYSFGIVLWEI
Kinase TESK2.AA TK 58-309 16 1.3e-44 147.03 In-house 1-486 (486) Show / Hide 
Range on Protein: 58-309
Range on HMM: 1-486/486
Sequence Identity: 16% (78 aa)

DFTREKIGSGFFS---EVFKV-------------------------RHRASGQVMALKMNTL---SSNRA----------------NLLKEMQLMN--RL
    .|.|.| |    ||.|                          ...   .  | || ..   .| ..                ... ||..|.   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPNILRFMGVCVHQ------------GQLHALTEYINSGN----LEQLLDS-DLY--------------------------------------------
 ||||.|. |||...            . .  ..|| . |.    | . | . . .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LPWTVRVKLAYDIAVGLSYLHFK------GIFHRDLTSKNCLIKRD--------ENGYSAVVADFG---
                               |.   ..  ...|| |..||| |      .. ||||   |||. ..        ..|. . .||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAEKIPDASIGREKLAVV---------------------GSPF---WMAPEVLRDEP---------YNEKADVFSYGIILCEIIARIQADPDY--
     || .|.. .  . |                         |  .   |||||.|.|           . .| ||.|.|. . ||  . |. .    
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------------LPRTENFGL-------DYDAFQNMV--GDCPS-------------DFLQL-TFNCCNMDPKLRPSFEEIGKTL
              . . .. |        .      |    .||.             .....    |.. ||. ||.|... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TESK2.AA LIMK 216-309 47 3.1e-44 148.56 In-house 192-287 (287) Show / Hide 
Range on Protein: 216-309
Range on HMM: 192-287/287
Sequence Identity: 47% (46 aa)

VVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVG--DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
||| |.||||| ..   |.|| ||||.||..|||| |..|.||..|||  |||.   |       .||  | ...| || |||  ||.|..  . |
VVGNPYWMAPEMMNGKSYDEKVDVFSFGIVMCEIIGRVYACPDCMPRTMDFGLNQQEFWEKCCPDQCPPPFFPIMFMCCDMDPDMRPCFDKLHQWL
S_TKc TESK2.AA S_TKc 58-316 24 4.5e-44 153.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 58-316
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

DFTREKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINS--GNLEQLLDSDLY------LP
    .|||.| |..|.|.||. .|...|.|.        ....|.|.. .  |||| .. .|... . |.  .||..   |.| .....  .      .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

WTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNE-KADVFSYGIILCE
  .  ...| |. .| |.| .|| ||||   | |. .        ..||||| ..           ..|.|..||||||   .|.  |.|. | |.|| |
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

IIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGK--TLKEIMSRL
 ...    |           ..  |....   .......  .|...||. ||.  |. .   .  ..  .
MLCGYPPFP----------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TESK2.AA STE 59-250 22 5.5e-43 149.14 In-house 1-262 (359) Show / Hide 
Range on Protein: 59-250
Range on HMM: 1-262/359
Sequence Identity: 22% (62 aa)

FTR-EKIGSGFFSEVFKVRHR------ASGQV---------MALK-------------------MNTLSSNRANLLKEMQLMNRLS--HPNILRFMGVCV
... ||||.| | .|.| ...       .|.|         || |                   .|. .... ..|||...|....  |||| .. | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HQG-------QLHALTEYINSGNLEQLLD---SDL-----------YLPWTVRVKLAYDIAVG-LSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFG
. |       .|.   ||.. | |.....   . .           ..| ..  . ...|  | |.||| ..| |||. . | |.        .  .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFG

LAEKIPD--------------ASIGREKLAVVGSPFWMAPEVLR------DEPYNEKADVFSYGIILCEII
.. .. |              .... .   .||.| ||||||..      | .|..|.|. | |. ..| .
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase TESK2.AA LIMK 62-201 45 3.2e-41 138.12 In-house 5-144 (287) Show / Hide 
Range on Protein: 62-201
Range on HMM: 5-144/287
Sequence Identity: 45% (65 aa)

EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRA--NLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLL-DSDLYLPWTVRVKLAY
|. | |||  ..|| ||..| || .|     .  .  . |||   |  | ||..| | ||      |. .||||  | |. .. | |  .||  ||..| 
EVLGKGFFGQAIKVTHRQTGEVMVMKELHRCDEETQRTFLKEVKVMRCLDHPHVLKFIGVLYKDKRLNMVTEYIKGGCLKNIIHDMDQPFPWQQRVRFAR

DIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLA
||| | ||||  .| |||| | |||.. |    | ||||||||
DIACGMSYLHSMCIIHRDLNSHNCLVREDR---SVVVADFGLA
Kinase TESK2.AA Pkinase 62-246 30 4.2e-40 142.88 Pfam 5-202 (293) Show / Hide 
Range on Protein: 62-246
Range on HMM: 5-202/293
Sequence Identity: 30% (61 aa)

EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLK------EMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSG----NLEQLLD--SDLYL-
.||||| |..|.| .|. .|.. |.|   ..... . ..      | |.|.||.||||.|. ...   . ..  .|| . |     |  ..   ..  . 
RKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY

-PWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK-RDENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLR-DEPYNEKADVFSYGII
 .. .  . .| |. || |.| .|| |||| . |.||. ..... .  ..|||||...     ..    ..|.|..|||||.| ...|  |.|..|.|.|
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCI

L
|
L
Kinase TESK2.AA MLK 60-252 28 1.4e-39 135.02 In-house 3-232 (291) Show / Hide 
Range on Protein: 60-252
Range on HMM: 3-232/291
Sequence Identity: 28% (67 aa)

TREKIGSGFFSEVFKVRHRASG---QVMALKMNT--------LSSNRANLLKEMQLMNRLSHPN----ILRFMGVCVHQGQ-LHALTEYINSGNLEQLL-
. |.|||| | .|.| | |.      . |.|. .         .. . .. .|  . ..|||||    | .|.|||  ... .  ..||.  | |  .| 
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLH

--DSDLY-----------LPWTVRVKLAYDIAVGLSYLHFKG---IFHRDLTSKNCLIKR---DENGYSAVVADFGLAEKIPDASIGRE-KLAVVGSPFW
  .|  .            .  . .. |...| |..||| .    | |||| |.| || .   | ..  ....|||.. ..   ... . .    |.. |
GARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDW--HQMC-TNMMSNAGTYAW

MAPEVL---RDEPYNEKADVFSYGIILCEIIAR
|||||.   | |.|.||.||.|.|..| |...|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTR
Kinase TESK2.AA TyrKc 58-309 26 5.8e-39 136.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 58-309
Range on HMM: 1-280/280
Sequence Identity: 26% (78 aa)

DFTREKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRL--SHPNILRFMGVCVHQ-------GQLHALTEYINSGNLEQLL-DSDLY
    .|.|.|.| ||.| . .   .  | ||   .. |. ...|...| .|  .||||.|. |||..|       ..|  ..||   |.| . | ..   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDA-------SIGR------EK--LAVVGSPFWMAPEVLRDEP
|..   .. ...|| | .||| |.. ||||   |||....     . ..||||. .| |        .  |      .|  | .     |||||....  
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI----RWMAPECINYGK

YNEKADVFSYGIILCEIIARIQADPDY-----LPRTENFGLDYDA-FQNMVGD--------CPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
...| ||.|.|. . ||  . |  .       .. .| . .  .        .        ||..  |.   |.. ||. ||.|.|| . .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TESK2.AA Pkinase_Tyr 62-250 28 2.3e-35 120.38 Pfam 5-208 (270) Show / Hide 
Range on Protein: 62-250
Range on HMM: 5-208/270
Sequence Identity: 28% (60 aa)

EKIGSGFFSEVFKVRHR----ASGQVMALKMN--TLSSN---RANLLKEMQLMNRL-SHPNILRFMGVCV-HQGQ--LHALTEYINSGNLEQLLDS----
.|.|.| | ||.| . .      ..  | ||   . ..    |. ...|...|  | .||||.|..|||. ....  .   .||   |.|   | .    
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRED

DLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIG-REKLAVVGSPFWMAPEVLRDEPYNEKADVFSYG
.  |.    .. ...|| |..||. |.. ||||  .|||...   .  . ..|||||  | . .   | .       .|||||....  ...| || |.|
KQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFG

IILCEII
. . ||.
VLMWEIF
Kinase TESK2.AA TKL-Unique 279-309 41 1e-06 19.58 In-house 260-290 (290) Show / Hide 
Range on Protein: 279-309
Range on HMM: 260-290/290
Sequence Identity: 41% (13 aa)

DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
.|| ..  |   |.. ||  ||||.|| . |
HCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase TESK2.AA Dicty4 279-311 40 2.7e-05 13.81 In-house 243-277 (277) Show / Hide 
Range on Protein: 279-311
Range on HMM: 243-277/277
Sequence Identity: 40% (14 aa)

DCPSDFLQLTFNCCNMDPKLRPSFEEIGKT--LKE
.||  . .|   | . ||. ||||||| .   | .
WCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase TESK2.AA MLK 279-309 41 5.2e-05 13.47 In-house 261-291 (291) Show / Hide 
Range on Protein: 279-309
Range on HMM: 261-291/291
Sequence Identity: 41% (13 aa)

DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTL
.||  . .|  .| |.||. |||| .| . |
TCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase TESK2.AA Pkinase 281-309 25 0.006686 11.34 Pfam 263-293 (293) Show / Hide 
Range on Protein: 281-309
Range on HMM: 263-293/293
Sequence Identity: 25% (8 aa)

PSDFLQLTFNCCNMDPKLRPSFEEIGKT--L
.......  .|...||| ||..|.| .   .
SEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TESK2.AA Pkinase_Tyr 291-309 47 0.051382 7.45 Pfam 252-270 (270) Show / Hide 
Range on Protein: 291-309
Range on HMM: 252-270/270
Sequence Identity: 47% (9 aa)

CCNMDPKLRPSFEEIGKTL
| . ||. ||.|.||   |
CWHYDPEDRPTFSEIHEQL