TRKA

Species: Mouse
Alias: Ntrk1, TRKA
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Trk

Sequence

Name Sequence Type Origin Length Description Download
TRKA.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 275 Kinase domain by global Sugen HMM Fasta, JSON
TRKA.NA RNA Sugen 2618 None Fasta, JSON
TRKA.AA Protein Sugen 799 None Fasta, JSON

Protein domain

Protein domains of TRKA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRCT TRKA.AA LRRCT 148-194 25 0.000868 15.33 SMART 1-55 (55) Show / Hide
Range on Protein: 148-194
Range on HMM: 1-55/55
Sequence Identity: 25% (14 aa)

NPLHCSCALFWLQRWEQE-GLCGVHTQ--TLHDSGPGD----QFLPLGH-NTSCG
||..|.| | |.||| |.     |. .   ..  .|..    . ... | . .|.
NPWNCDCHLRWFQRWLQQQHNRHVQDPQSDMRCASPEHMRGQPLFHYLHSDFKCP

IG TRKA.AA IG 202-285 18 8.3e-05 23.22 SMART 1-58 (58) Show / Hide
Range on Protein: 202-285
Range on HMM: 1-58/58
Sequence Identity: 18% (16 aa)

MPNDSVEVGDDVFLQCQVEGLALQQADWILTELEGAATVKKFGDLPSLGLILVNVTSDLN--KKNVTCWAENDVGRAEV--SVQVSVS
 |  .| .|..| |.| |.     |  |                     |.. ||. .    . . .| |.   | ..   .....|.
PP-VTVKEGETVTLTC-VS-----QIWWY--------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

Kinase TRKA.AA Trk 513-784 75 3.8e-221 740.96 In-house 1-275 (275) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-275/275
Sequence Identity: 75% (208 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAK
|.|||||||||||||||||||||...||||.||||.||.||||||.||||||||||.|||||||.|.||||.. |||||||||.|||||..||.|||||.
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDAM

LLAGGED-VAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS-TDYYRVGGRTMLPIRWMPPESILYRKFSTE
..|.... .|||||...|.|..|.|.|.||||.||.||||||.|||||||||.|.|||||||||||.|| |||||||..|||||||||||||.||||..|
CYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTYE

SDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRE-LERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARL
|||||||||.||.|||||||||||||.|.||||.|||. |||||.||..||.||.||||||||||...||.|...
SDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII

Kinase TRKA.AA TyrKc 513-784 43 7.4e-145 488.45 SMART 1-280 (280) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-280/280
Sequence Identity: 43% (134 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTML--QHQHIVRFFGVCTEG-------GPLLMVFEYMRHGDLNRF
| |. .|||||||.|.... .        . |||| ||| .   |.|| |||.....|  .|..|||..||||..       .||..|.||| ||||. .
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYST-------DYYRV----GGRTML
||.|.|.              | . .||  . |.|.|| ||.| ...|||||.|||||| ...|||.|||.|||||.        ||||.    ||.|||
LRKHRPK--------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML

PIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQ-----LSNTEAIECITQGRELERPRA--------CPPDVYAIMRGCWQREPQQRLSMKD
|||||.||.| |.||.|.||||||||..|||||||.||..      .||.|.||.. ||. ...|          ||...| ||. ||...| .| ....
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

VHARL
.| ..
IHECF

Kinase TRKA.AA Pkinase_Tyr 513-784 45 5.2e-142 481.58 Pfam 1-270 (270) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-270/270
Sequence Identity: 45% (129 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENA---RQDFQREAELLTML-QHQHIVRFFGVCT-EGGP--LLMVFEYMRHGDLNRFLR
|..  .|||||||.|......  . |..|. |||| ||| .      |.|| |||.... | .|..|||. |||| .|.|  ...|.||| ||||  .||
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY-RVGGRTMLPIRWMPPESILY
.|              ..|| . .||  . |.|.|| ||.| ...|||||.|||||. ..||||.|||..||||..||| |..| ..|||.||.||.| |
KHR-----------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINY

RKFSTESDVWSFGVVLWEIFTYGKQP-WYQLSNTEAIECI-TQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARL
.||.|.||||||||..|||||||.|| .. .||.| .| |  .|. ...|. ||...| .|. ||. .|..| .....| .|
GKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase TRKA.AA TK 513-784 26 3.8e-123 414.94 In-house 1-486 (486) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-486/486
Sequence Identity: 26% (129 aa)

IILKWELGEGAFG---KVFLAECYNLLNDQDK--------------------MLVAVKALKEASENARQDFQR--------------EAELLTMLQ----
|.|  .||||.||   .|...| ...  .. |                    . |||| ||| .... ..|.               ||| . |..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HQHIVRFFGVCTEG------------GPLLMVFEYMRHGD----LNRFLRSHGPDAKLLAGGED-----------------------------------
 |..|||..||||.|            .|...| ||| |||    |  .||.. |...  . . |                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------VAPGPLGLGQLLA-------------------VASQVAAGMVYLASL------HFVHRDLATRNCLVGQGLV-----------VKIGDFGMS--
       .| ||.. .||                     . |.|.|| ||.|.      .|||||||.||||||...|           .||.|||.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RDIYSTDYYRVGG------------------------RTMLPIRWMPPESIL---------YRKFSTESDVWSFGVVLWEIFTYGKQPWYQ-LS
      ||||| |.|.. .                        ...||||||.||...         |.||.|.||||||||..|||||||..|.|  .|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------TEAIECITQG--------------RELERPRACP--------------PDVYAIMRGCWQREPQQRLSMKDVHARL
|         .| .|....|               ....|  ||              ...| .|. ||...|..| .....| .|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase TRKA.AA Musk 513-784 46 4.7e-120 398.5 In-house 1-282 (282) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-282/282
Sequence Identity: 46% (131 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKE-ASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDA
||   ..|||||| || |    |. ... ..|||| ||. ||.   .|||||| ..    |. ||.  |||  | |. . ||||  |||| ||.|  | .
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR

KLLAGGEDVA-------PGPLGLGQL--LAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESI
   .  .| .       |||..|  .  | .| |.|.|| ||    ||||||||||||..   .||| |||.|| ||. |||.  .    ||||||||||
TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESI

LYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARL
.| .|..|||||..||.||||| |. ||.| ..  | |  | ||  |  |  || .||..|| |||..|  | . ...|  .
WYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI

Kinase TRKA.AA Ror 513-787 47 3e-118 399.13 In-house 1-278 (308) Show / Hide
Range on Protein: 513-787
Range on HMM: 1-278/308
Sequence Identity: 47% (131 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENA-RQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDA
.    ||||..||||.  . . ... .  |.||.|..|.  ..| .|||..|..|   |.|. ||   ||||   |..|.|||| ||||  || .. | .
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFLIMRSPHS

KLL-AGGED-VAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFST
      ..|      |  .  | .| |.|||| ||.| ||||||||.|||||| ...||| ||| .||||| ||||. .. ..|||||.||.|.| |||.
DHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSE

ESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQAL
.||.||||||||||. || ||.|  || | || | .   |. |  ||. .|. |  ||   |  |   ||.| ||...
DSDIWSFGVVLWEIWSYGMQPYYGYSNQEVIEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIHSRLRSW

Kinase TRKA.AA InsR 513-786 41 8.60000000001e-109 366.57 In-house 1-278 (278) Show / Hide
Range on Protein: 513-786
Range on HMM: 1-278/278
Sequence Identity: 41% (117 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKM--LVAVKALKE-ASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGP
|.|  |.|.|.||.| .    ... |       .|.| ..| ||   | .|  ||.      . |.|| .|||. | | . | | | .|||  .|||. |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

DAKLLAGGEDVAP---GPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRK
...     . . .    .  |.|..  |.... || |||.. ||||||| |||.| . . |||||||| |||| .|||| ||. |||.|||.|||.   .
EEEF---NNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGV

FSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECI-TQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQA
|.| ||||||||||||. | | ||   ||| .. . |   |  |..|  ||. ....|. |||  |. | . .|. . |. 
FTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD

Kinase TRKA.AA UTK 513-784 36 6.9e-108 364.73 In-house 1-296 (296) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-296/296
Sequence Identity: 36% (110 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK--EASENARQ---DFQREAE---LLTMLQ-HQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRF
..|  .||.|||| |..|.  .  .   .|.||||...  .... ..    || .||    .. ... |....|. |||| ..|...| |||. |||  .
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQG-------LVVKIGDFG---MSRDIY---------STDYY
||.|.|..         .|  | | |.|  |...|.|| ||.| .||||||| |||||..        .|.||.|||   |||...         ...||
LRRHRPTPP-------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYY

RVGGRTMLPIRWMPPESILYR-KFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQG--RELERPRACPPDVYAIMRGCWQREPQQRLSMKDVH
.  .....||||| ||.. .. .|.| |||||||||.|||.|.|..|.  .|| .... .. |  . ...|..|| .|| .|. ||. .|| | ...|. 
MAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLV

ARL
...
QQM

Kinase TRKA.AA DDR 513-784 40 1.2e-97 330.68 In-house 1-306 (306) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-306/306
Sequence Identity: 40% (124 aa)

IILKWELGEGAFGKVFLAECYNLL-----------NDQDKMLVAVKALKE-ASENARQDFQREAELLTMLQ-HQHIVRFFGVCTEGGPLLMVFEYMRH-G
 | .  .||| || | | |  ...           .  . .||||| |.. |...||.|| .|.  .  .  |  ||| .||||.  |..|. |||   |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLNRFLRSHGPDAKLLAGGE---DVAPGP-LGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFG--MSRDIYSTDYYRVGG----
||| |.  | .  . | . .   . . .| .  .... .. |.|.|| ||.|. ||||||||||||||  . .|| |||  |||  || ||||| |    
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-RTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGK-QPWYQLSNTEAIECI-----TQGRE--LERPRACPPDVY-AIMRGCWQREPQQRLSMK
 |  .||||| .||||  ||.| ||||.||| .||.|.  . ||. ||..   || .     .||..  | .|..|| ..|   |  ||.|...|| | .
QRHHMPIRWMAWESILLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPMCPYEIYNQLMCRCWRRDQSQRPSFE

DVHARL
 .|  |
EIHKFL

Kinase TRKA.AA TK-Unique 513-784 36 4e-94 319.01 In-house 1-294 (294) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-294/294
Sequence Identity: 36% (107 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKM-LVAVKALK-EASENARQDFQREAELLTMLQ-HQHIVRFFGVCTEGG-PLLMVFEYMRHGDLNRFLRSHG
. .. ..|||||| |. .|  ..  ..||   ||||.|| .|..  .||| .|....  |  |..||...|.||. . | ....||.. |.|  .||. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PD-----------AKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAS--LHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIY-STDYYRVGGRTMLPI
|.            ..    ... . |. ...|.  | |.| || ||||   ..|||||..||.|.. ..|.||.||||.||.|  ..| . ... ..||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMPPESIL--YRKF-STESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRAC-PPDVYAIMRGCWQREPQQRLSMKDVHARL
|||.|||..  .. . .|.||||||||..|||||.|..| ....... .|||..|  ...|  | ....| .|. |||.||..| |  ..  ||
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase TRKA.AA ALK 513-786 42 1.2e-88 300.83 In-house 1-273 (273) Show / Hide
Range on Protein: 513-786
Range on HMM: 1-273/273
Sequence Identity: 42% (118 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKE-ASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDA
| |   || |||| |. ..   . .|  .| ||.| |.| .|.    ||  ||  .   .|| .||  |.| .  |.. | |||  ||. .|||   |  
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPHP

KLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLV---GQGLVVKIGDFGMSRDI-YSTDYYRVGGRTMLPIRWMPPESILYRKF
. |       | .|    || ..  ||.|  || . ||.||| | ||||    | | |.||.||||.||| | .|||| |||.|.|. |||||  .   |
ESL------QPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDGIF

STESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQA
 . .||||||| .||||  |  |    .|.| .| .|.|  .. || ||  || ||. ||| .|  | .  ..  ..|.
TSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY

Kinase TRKA.AA CTKB 513-786 42 1.2e-87 297.44 In-house 1-269 (269) Show / Hide
Range on Protein: 513-786
Range on HMM: 1-269/269
Sequence Identity: 42% (118 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELL-TMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDA
|.||  |||| || |.  |   .. ||    ||.| |...|  |  || .|  .. |.   | |||  |.||   | ||| | |  |||   ||   |  
IVLKQKLGEGHFGVVYAGEAKKIMPDQAVTPVAIKMLQDSSSEATNDFMKEVKIMQTIDGDQKIVRLLGICTRETPFLMVLELMAKGDLKTLLRNSRPKT

KLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTES
          |  |    |  .|  || || |.||.  |||||| ||||| |   | |||||.|||.|   ||   .   |||||| ||||    ..| |
--------SKPSALSPRRLALMAADVADGMAYIASKRIVHRDLAARNCLVHQNWRVCIGDFGISRDVYMREYYKMQASNPLPIRWMSPESINDGVYTTQS

DVWSFGVVLWEIFTYGKQPWYQ-LSNTEAIECITQG-RELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQA
||||.|.|.||| |..| |.   ..| | .| |. .   . .|. || ..|. |  ||  ||  | | |. | ..  
DVWSYGIVIWEIMTFAKMPYPEYETNMEVVERICDEDYRMWQPKECPDEFYDLMMQCWDEEPDDRISFKELHEKTLL

Kinase TRKA.AA S_TKc 513-787 21 5.4e-51 176.65 SMART 1-231 (231) Show / Hide
Range on Protein: 513-787
Range on HMM: 1-231/231
Sequence Identity: 21% (60 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRH--GDLNRFLRSHGPD
  .  ..|.||||||...   .     .. .||.| .|       ....|| ..| . .| .||....|. . . | ||.||. .  ||| ......|. 
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

AKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFST-
 .         . |.   .   .. |.. .. |. |....||||   | |. .  ..||.|||..| .                 .|.|| .   .... 
GL---------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKC

ESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHA------RLQAL
..|.||.|..|.| .. |. |..   . ...  .            .|..  ..|.|.|..|..|..  .. .        . .
KCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TRKA.AA Pkinase 513-784 19 1.8e-47 168.81 Pfam 1-293 (293) Show / Hide
Range on Protein: 513-784
Range on HMM: 1-293/293
Sequence Identity: 19% (62 aa)

IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQD--FQR--EAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHG----DLNRFL
. ..  .|.|.||.|     |   .  .  .|||| .|  .|.  .|    |  |.... .|.| .|||......... . ||.||...|    || ...
YHIGRKIGSGSFGCV-----YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

RSHGPDAKLLAGGEDVAPGPL--GLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVV----KIGDFGMSRDIYSTDYYRVGGRTMLP--IRW
.               . |..     ..  .. |.. |. |. |  ..||||   |.|. .  ..    ||.||| .. ..   | . .  | .   ...
ST-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWY

MPPESIL-YRKFSTESDVWSFGVVLWEIFTYGKQPWYQL----SNTEAIECITQGRELERPRACP-----------------------PDVYAIMRGCWQ
|.|| |. ... ....|.||.|..|.| .. |. |...     .  . ...| . .. . .. .|                       ..   ....|..
MAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

REPQQRLSMKDVHAR--L
. |..|.. ...     .
KDPKKRPTAEQILQHPWF