Gene TXK (Mouse)

TXK

Species: Mouse
Alias: Txk, TXK
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: TK
Family: Tec

Sequence

Name Sequence Type Origin Length Description Download
TXK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
TXK.NA RNA Sugen 2204 None Fasta, JSON
TXK.AA Protein Sugen 527 None Fasta, JSON

Protein domain

Protein domains of TXK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 TXK.AA SH3 85-141 41 4e-19 70.76 SMART 1-58 (58) Show / Hide 
Range on Protein: 85-141
Range on HMM: 1-58/58
Sequence Identity: 41% (24 aa)

IQVKALYDFLPREPGNLALKRAEEYLILERCDPHWWKARDR-FGNEGLIPSNYVTENR
 .|.||||. ...|. | .|. . ...||..|..|||.| .  |.||..|||||.| .
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 TXK.AA SH3_1 88-134 34 3.1e-15 54.36 Pfam 1-49 (49) Show / Hide 
Range on Protein: 88-134
Range on HMM: 1-49/49
Sequence Identity: 34% (17 aa)

KALYDFLPREPGNLALKRAEEYLILERCDP-HWWKARDRFGN-EGLIPS
.||||. ...|. | .|. ... ..|. |  .|||.|.  .. ||..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH2 TXK.AA SH2 150-231 40 7.9e-42 124.64 Pfam 1-81 (81) Show / Hide 
Range on Protein: 150-231
Range on HMM: 1-81/81
Sequence Identity: 40% (34 aa)

WYHKNITRNQTERLLRQ-EAKEGAFIVRDSR-HLGSYTISVFTRARRHTQSSIKHYQIKKNDSGQWYITERHLFPSVPELIQYH
|||..|.|.. ||||.. . ..|.|.||.|. . |.||.||..  .   ....|||.|...| |..|||.|| |.|..||....
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP---GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 TXK.AA SH2 148-237 40 3.5e-36 127.46 SMART 1-87 (87) Show / Hide 
Range on Protein: 148-237
Range on HMM: 1-87/87
Sequence Identity: 40% (38 aa)

YEWYHKNITRNQTERLLRQE-AKEGAFIVRDSRH-LGSYTISVFTRARRHTQSSIKHYQIKKNDSGQWYITE--RHLFPSVPELIQYHQYNAAG
..||| ||.| . |.||...  ..|.|.||||..  |.|..||...      . .|||.|..||.|..||.|  |. |||. ||....| |. |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase TXK.AA Tec 271-522 74 4.5e-216 724.12 In-house 1-254 (254) Show / Hide 
Range on Protein: 271-522
Range on HMM: 1-254/254
Sequence Identity: 74% (188 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKAL--LL
|.|.||.|||||||||||.||... ||||.|.|||||||||||||||||||||..||||||||.||.|.|||||.||.||||.||||.|...||..  ||
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

SMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFE
.||||.|||||||||.|.||||||||||||...||||.|||||.||||||.|.||.|.|||||||||||||...||||||||.|||||||||..||||.|
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

NKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTE
|.||..|||..|||.|||||||..|.||..||.||||.|..||||..||. .||
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase TXK.AA Pkinase_Tyr 271-520 48 7.4e-147 497.99 Pfam 1-270 (270) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-270/270
Sequence Identity: 48% (130 aa)

LAFVKEIGSGQFGVVHLGEWR-----AHIPVAIKAINEGSMSE----EDFIEEAKVMMKL-SHSRLVQLYGVCI-QQKP--LYIVTEFMENGCLLDYLRE
. | |..|.|.||.|..|.|.      .||||.| ..||.|.|    |||..|||.|..| .|  .|.|||||. |..|  .|||.|.|..|.||||||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---KGQLQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYV-LDDEY-ISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSF
.   |..|    ||.||..|..||.|||.  .||||||||||||..  ||||.|||.||..  ||.|  ...|.|.|.||..||.....|...|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GVLMWEVFTEGKMP-FENKSNLQVVEAI-SQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVL
||||||.|| |..| ... || .|.|.|  .| |. .|...|  ||..| .|||. |. ||||.|... |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase TXK.AA TyrKc 271-520 41 7.89999999999e-137 461.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-280/280
Sequence Identity: 41% (119 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKL--SHSRLVQLYGVCIQQ-------KPLYIVTEFMENGCLLDYLRERKGQ
. . |..|.|.||.|..|.|.  |.||.| ..|..  .|||..||..|.||  .|  .|.|||||.||       .||.||.|.|..|.|.||||.....
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDD-------EYISSS---GAK--FPVKWCPPEVFHFNKYSSKSDV
|. . |||.| .|..||.||.. ..||||||||||||..  .|||||||..|.. ||       .|....   |.|  .|..|..||.. ..|...||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGVLMWEVFTEGKMPFEN-----KSNLQVVEAISQGFRLYRPHL--------APMTIYRVMYSCWHESPKGRPTFAELLQVL
|||||.|||.|| |..| ..     .|| .|.| . ||.|. .|.         .|  .|..| .|||| |. ||||.|. . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TXK.AA Src 271-520 46 1.8e-125 423.17 In-house 1-255 (255) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-255/255
Sequence Identity: 46% (118 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLR-ERKGQ-LQKALLL
. .....|.|||| |  | |. ...||.| . .|.|| |.| .||..| ||.| .||||| || | .| |||||.|..|.|||||. ...|. |.   |.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

SMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVL--DDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMP
.|   . |||||||.  |||||||||| ||.   |.|. ||| || .   |||| ...|||||.||  || ....... ||||||||.|..|..| |..|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

FENKSNLQVVEAISQGFRLYRPHLAPMTIYR-VMYSCWHESPKGRPTFAELLQVL
 .  .| .|......|.|. .||  |  .|  .|  |||..|. ||||. | ..|
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase TXK.AA TK 271-520 24 5e-119 400.87 In-house 1-486 (486) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-486/486
Sequence Identity: 24% (120 aa)

LAFVKEIGSGQFG---VVHLGEWRAH--------------------------IPVAIKAINEG-SMSEEDFIE--------------EAKVMMKLS----
. ..|..|.||||   .|..|||| .                          .|||.| . || .||.|.|..              || .|....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HSRLVQLYGVCIQQ------------KPLYIVTEFMENGC----LLDYLRERKG---------------------------------------------
 |  .|.||||| |.            .|..||.|.|..|.    |.||||....                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLQKALLLSMCQDICEGMAYLERS------CYIHRDLAARNCLVSSACV-----------VKISDFG---
                              ||  . || ||..|..||.||..        ..|||||||||||..  |           .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----MARYV-LDDEYISSS------------------------GAKFPVKWCPPEVFH---------FNKYSSKSDVWSFGVLMWEVFTEG-KMPFENK
     .||..  ||.| ..|                        |.|.|..|..||..          ..|...|||||||||||||.|| | ... .. 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------LQVVEAISQG--------------FRLYRPHLAP--------------MTIYRVMYSCWHESPKGRPTFAELLQVL
||          .|.| . .|              .|. .| ..|                .|..| .|||. |. ||||..|.. |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TXK.AA SFK-Src 271-524 44 2.1e-113 337.53 In-house 1-259 (259) Show / Hide 
Range on Protein: 271-524
Range on HMM: 1-259/259
Sequence Identity: 44% (116 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQ-LQKALLLS
 .  |  |||||| |  | |     ||.|    |.||.| | .|| || || | .|.||| ||    |.||.|| | .| |||||.| .|. |.  .|  
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVL-DDE-YISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPF
|  ..  ||||||   ..|||||||| ||    |.|. ||||.| .  ||| |    |||||.||  ||    |..| ||||||||.|| |. | | .|.
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

ENKSNLQVVEAISQ--GFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIA
.  .|  |.  . .  | |.  |   |   | .|  || . |  ||||  |.  . .  
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase TXK.AA Src-Unclassified 271-520 39 1.7e-100 340.17 In-house 1-284 (284) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-284/284
Sequence Identity: 39% (112 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEG---SMSEEDFI--------EEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERK
.  ....| |||| | .| ||  . ||.|   .|    || | |         .||..| |..| .||.||.|| | .| ||.||.| || ||..|||  
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GQLQKALLL-------------SMCQDICEGMAYLERSCYIHRDLAARNCLVSSAC-----VVKISDFGMA--RYVLDDEYISSSGAKFPVKWCPPEVFH
||.    ..             ..   .  || |||   |.|||||||| |.         |||. ||| |  . . ||.|.   ||.||.||  || | 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

FNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRP--HLAPMTIYR-VMYSCWHESPKGRPTFAELLQVL
  . | ||||||.|.| ||..| |. |     |  |.| .. |.|. .|  |. |  ||  .|  |||. |  ||||  |   .
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase TXK.AA SrcB 271-521 47 3.7e-99 335.71 In-house 1-251 (251) Show / Hide 
Range on Protein: 271-521
Range on HMM: 1-251/251
Sequence Identity: 47% (119 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKG-QLQKALLLS
| .|| .|.|||| | .| .. |. ||.|.. .|.|| | |..|| || .| | |||.|| |  .  |.||.||.|..|||||.|.  .| .|.   |. 
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFEN
|   | |||||.||  |||||| | | ||| . . || |||.|| . |.||    |||||.||  ||  .|  .  ||||||||.|. |. | |..|.  
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

KSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLT
..| .|......|.|. ||   |  .|..|  ||.| |  ||||  |  || 
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase TXK.AA UTK 271-520 34 2.4e-97 329.68 In-house 1-296 (296) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-296/296
Sequence Identity: 34% (102 aa)

LAFVKEIGSGQFGVVHLGEWRA---HIPVAIKAINEGS------MSEE---DFIEEAK---VMMKLS-HSRLVQLYGVCIQQKPLYIVTEFMENGCLLDY
... ...|.|.||.||.....    | .....|. . .       ..|   ||.|||.   .|.... |  ...|.||| |..|..||||.|||| |..|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LR-------ERKGQLQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSA-------CVVKISDFG---MARYVL----------DDEYISSSGAK
||       ..  .| .  .|.|. || .||.||..  ..||||||||||| .         |.||.|||   |.|.|           ...| ...  .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPVKWCPPEVFHFN-KYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQG--FRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVL
 |..|. ||..  . ....|||||||||..||..| |..|... || ||..... |   |. .|.  |...||.| .||| .|  ||.| .|.|..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase TXK.AA Frk 271-524 44 7e-97 328.17 In-house 1-260 (260) Show / Hide 
Range on Protein: 271-524
Range on HMM: 1-260/260
Sequence Identity: 44% (116 aa)

LAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLR--ERKG-QLQKALL
. .....|||||| |  | |   .|||.| .  |.|  .||. ||..| || |..|.||| ||  ..|.||.|| |..| |..||.  ..|| |.|   |
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

LSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMAR-YVLDDE--YISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGK
. |   .  ||||||   |||||||||| ||    ..|| |||.||  . |.|  | |  ||.||.||  ||  . ||.. ||||||||.|. |. | |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

MPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIA
||.    | .|.. ...|.|. .|   | ..| .|  |||. |. ||||  |   | .  
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase TXK.AA Abl 271-520 45 3.7e-95 317.91 In-house 1-252 (252) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-252/252
Sequence Identity: 45% (114 aa)

LAFVKEIGSGQFGVVHLGEWRAH-IPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRE-RKGQLQKALLL
.   . .| ||.| |  | |. |   ||.|.. | .|  ..|..|| .| .. |  |||| ||| .  | ||.|||| .| |||||||  . .|.   ||
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

SMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFE
 |   |  || |||.  .||||||||||||.   .||. |||.|| . || |    |||||.||  ||   .||.||||||| ||||.||. | |  |. 
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYP

NKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVL
     .| . . .|.|. ||.  |  .|..|  ||. |.  ||.|.|. . .
GIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase TXK.AA TK-Unique 271-520 31 7.2e-92 311.51 In-house 1-294 (294) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-294/294
Sequence Identity: 31% (92 aa)

LAFVKEIGSGQFGVVHLGEWRA-------HIPVAIKAINEGSMSEE--DFIEEAKVMMKLS-HSRLVQLYGVCIQQK-PLYIVTEFMENGCLLDYLRERK
| . ..||.|.|| |. || .        .. ||.|. ....  ..  ||  |...|..|  |  .||..|.|.    | .|. |....|.|..|||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

GQ-------------------------LQKALLLSMCQDICEGMAYLERSCY--IHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSG--AKFPV
..                         ..  .|.. . .|. ||.||..  .  .||||.|||.|... .|.||.||||||.| ... .|...   . |.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWCPPEVFH--FNKY-SSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLA-PMTIYRVMYSCWHESPKGRPTFAELLQVL
.|..||..    . | ..|||||||||||||.|| |..|. . .. ...|.| .|.|. .|    . ..| .|.|||...|. ||.|......|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase TXK.AA S_TKc 271-520 25 8.2e-53 182.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-231/231
Sequence Identity: 25% (67 aa)

LAFVKEIGSGQFGVVHLGEWRA-HIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMEN--GCLLDYLRERKGQ-----L
  ....||.| ||.|... ..  .  |||| |.      |... | ....|  |  .|.||.|.   . ||.|.|....  | |.||...|...     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSS-KSDVWSFGVLMWEVFT
      .... ||....|. .   |||||   | |...  ..||.|||.|| .        .       ...|||.   .|.  |.|.||.|....| ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

EGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQ---------VL
 |. ||.     .. . |            .      .  |..  |. |||  |.||          .
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TXK.AA Pkinase 271-520 23 2.4e-41 147.29 Pfam 1-293 (293) Show / Hide 
Range on Protein: 271-520
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

LAFVKEIGSGQFGVVHLGEWRAH-IPVAIKAINEGSMSEEDFIE-----EAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENG----CLLDYLR-ERK
. ... |||| ||.| .. ..   . ||.| |.  . ...  ..     |...| .|.|   |.||...   . .|.|.|..|.|     | ||.. .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GQL--QKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVV----KISDFGMARYVLDDEYISSSGAKFPV---KWCPPEVFH-FNKYSSKSDV
| .  .   . ...  |..|..|. .   |||||   |.|... ...    ||.||| |. .    | ..| .. ..    ...|||    ..|..|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGVLMWEVFTEGKMPFENK------SNLQVVEAISQ-GFRLYRPHLAP-------------------MTIYRVMYSCWHESPKGRPTFAELLQV--L
||.|....|... |. || ..      . .|... | .  ..  .| . .                    .   ....|..  || |||....||   .
WSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF