Gene YANK1 (Mouse)

YANK1

Species: Mouse
Alias: A930015B13Rik, YANK1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: AGC
Family: YANK

Sequence

Name Sequence Type Origin Length Description Download
YANK1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
YANK1.AA Protein Sugen 398 None Fasta, JSON
YANK1.NA RNA Sugen 3767 None Fasta, JSON

Protein domain

Protein domains of YANK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YANK1.AA YANK 23-281 74 3.5e-230 770.98 In-house 1-261 (261) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-261/261
Sequence Identity: 74% (195 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDT
|.||||||||||||||||.|.||||||||||||||||.||.||||||.||||||..|||||||||||||||||||||.||||||||||||||||||.|||
FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQKMEHPFLVNLWYSFQDEEDMFMVCDLLLGGDLRYHLQQNVHFSEDT

VKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMFTSRK--ETGYSFAVDWWSLGVTAYELLRGR
|||.|||..|||.|||...|||||.|||||||||||||||||||||.||....|.|...|||||||||.|....  ..|||..||||||||.|||.|||.
VKLYICEMCMALEYLQEMHIIHRDIKPDNILLDEHGHVHITDFNIATMLKDNQRATSMSGTKPYMAPEIFQCYMDECKGYSYPVDWWSLGVCAYEMLRGW

RPYHIRSSTSSKEIVNMFETAIVTYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQNFPYM
|||||.|.|...||..||.|..|.|||.|.||||.||.|||...|..|.|.|.|||..|||
RPYHIHSNTPIEEIYHMFSTNSVHYPSHWCQEMVDLLRKLLTVDPEHRISSLQDIQKHPYM
Kinase YANK1.AA AGC 23-281 26 5.8e-143 372.28 In-house 1-395 (395) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-395/395
Sequence Identity: 26% (108 aa)

FEILRAIGKGSFGKVCIVRKN------DTKKMYAMKYMNKQK-CVERN--EVRNVFKE------------LQIMQGLE----------HPFLVN-LWYSF
||.|. |||||||||. |||.      ||.|.|||| ..|..  |...  .|...  |             .|.. .           |||.|. |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDEED--MFMVVDLLL---------GG-DLRYHLQ---QNVHFQEDTVKLFICE-------LAMALDYLQS-QRIIHRD-MKPDNILLDEHGHVHITDFN
||..    ..| ...          || .| .|||   .. .| |.... ...|       ...||.|| | . ||||| .||.||||||.||...||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IAAMLPKE---------------------------------------------------TRITTVAG--TKPYMAPEMFTSRKETGYSFAVDWWS--LGV
 . .....                                                    | .|  |  |  |||||..       |..|.||||  ||.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------YGKACDWWSFGLGC

TAYELLRGRRPYHIRS------------STSSK-EIVNMFETAIVTYP----------SAWSQEMVSLLKKLLEPNPDQRFSH---------LTDIQNFP
  ||.| |. |..  .             .  | .. ..| .  |..|          . .|.| ..|.||||...|..|              .|.| |
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

YM
. 
WF
Kinase YANK1.AA S_TKc 23-281 32 5.7e-87 296.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLG--GDLRYHLQQNVH---
.|||| ||||.||||. .|...|.. .|.| ..          ... .|.||..   ||..|.| ..||| ....|| ... |  |||. ..... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMFTSRKETGYSF-AVDWWSLGVTA
   | | ... ...... ||.|. |..||||| ||.||||||  |. |.|| .|. |      ||. ||  |||||..      ||.. ..||||.|.. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCIL

YELLRGRRPYHIRSSTSSKEIVNMFETAIVTYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQ------NFPYM
||.| |. |..        ..  ||.          |.|. ....|.|. .|..| .     |      . |..
YEMLCGYPPFP--------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YANK1.AA SGK 23-281 33 7.1e-81 249.4 In-house 1-283 (283) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-283/283
Sequence Identity: 33% (97 aa)

FEILRAIGKGSFGKVCIVRKNDT------------------KKMYAMKYMNKQKCV-------ERNEVRNVFKEL-QIMQGLEHPFLVNLWYSFQDEEDM
|..|  |||||||||  |.. |.                  .|.||||  .||  .        ..|....  |   |.. . |||.||| |.|| ..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAA-MLPKETRITTVAGTKPYMAPEMFTSR
..| | . ||.. ||||   || || ..    |.. ||.|| || ||.|| ||.|||||  ||. .|||  .     ...  .| .||  |.|||.   .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

KETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAI---VTYPSAWSQEMVSLLKKLLEPNPDQRFSHL---TDIQNFPYM
   ... .||||.||   ||.. |  |.       |.    |..  |      |   | .  .|.. ||. .|..|  .     .|.| |. 
---PHDRTVDWWCLGCVLYEMMYGLPPFY------SRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase YANK1.AA RSK 26-281 34 9.3e-80 271.28 In-house 1-278 (278) Show / Hide 
Range on Protein: 26-281
Range on HMM: 1-278/278
Sequence Identity: 34% (97 aa)

LRAIGKGSFGKVCIVRKN---DTKKMYAMKYMNKQKCVERNE-VRNVFKELQIMQGLE-HPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVH---
|.  |.|..||| ..||    ||.. ||||  .| | | |.  .| ...| .|..  . |||.|.| |.||.|.  ... ... ||.| .|||. .|   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDE---HGHVHITDFNIAAM-LPK-ETRITTVAGTKPYMAPEMFT--SRKETGYSFAVDWWSLG
| ||...  . |...|...| .| ||||| ||.|||.|.   .||. .|||  .    .. . .  |  .|  |||||| .    .. |.. |.||||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLG

VTAYELLRGRRPYHIRSST-SSKEIVNMFETAI--VTYP--SAWSQEMVSLLKKLLEPNPDQRFSH----LTDIQNFPYM
|  ||.| |..|..  .   ..||| .  ...   .| |  .  |||. .|..|.|. .| .| .     . .|.. |..
VLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YANK1.AA Akt 23-268 38 3.6e-77 246.22 In-house 1-247 (264) Show / Hide 
Range on Protein: 23-268
Range on HMM: 1-247/264
Sequence Identity: 38% (98 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMY-AMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQED
|..|. .||||||||  |.|.||.|.| |||   |......|.|.... |  | |   |||.||| ||||...  ..| |   ||.| ||||.   | ||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TVKLFICELAMALDYLQSQRIIHRD-MKPDNILLDEHGHVHITDFNIAAML-PKE-TRITTVAGTKPYMAPEMFTSRKETGYSFAVDWWS-LGVTAYELL
. . ...|.  |...| |. || || .|| |||.|..||. .|||  . .   |.  . .|. ||  |.|||.    . .|.. |||||. ||.  ||..
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEIL---NGNGHTKAVDWWGSLGCVMYEMM

RGRRPYHIRSSTSSKEIVNMFE---TAIVTYP--SAWSQEMVSLLKKLLEPNPDQR
 || |..      .. .  ||.   .. | .|  ...|.|  .|...||. .|..|
CGRPPFY------NQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKR
Kinase YANK1.AA Pkinase 23-281 28 3.3e-75 260.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVF-KELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGG----DLRYHLQ--QN
..|.| ||.||||.|.. .. .| |..|.| ..|..  .  .....   |.|||. | ||. | |...|.|. .. || ... ||    ||  ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VHF--QEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHV----HITDFNIAAM--LPKETRITTVAGTKPYMAPEMFTSRKETGYSFAVDWW
  |  .|...| .. ... .|.|. |..|||||.||.|||.|..||.    .|.|| .|.   . . .  ||..|| .|||||    |. ..|. .||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDMW

SLGVTAYELLRGRRPYHIR----SSTSSKEIVNMFETAIVTYPSAWS---------------------QEMVSLLKKLLEPNPDQRFSHLTDIQNFPYM
|.|.. ||.| || |.  .    .  . ......   ... ... |.                     .|. ...|..|...| .| .  ..| . |..
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPWF
Kinase YANK1.AA RSK-Unclassified 23-268 37 3e-71 222.91 In-house 1-266 (283) Show / Hide 
Range on Protein: 23-268
Range on HMM: 1-266/283
Sequence Identity: 37% (101 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQ--QNVHFQE
|.  | ||.|.||||  ||| ||...|||| ..|.| . .| .. |  |  ||   .||| | | .||| .  .... .   |||.  |||      | |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFN--IAA--------------------MLPKETRITTVAGTKPYMAPEMFTSRKET
| |. .. |  .|| ||  . .| ||.|||||.|.  |||  |||   | |                     .   .|     ||  |.||||    .  
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMI---RRC

GYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIVTYP--SAWSQEMVSLLKKLLEPNPDQR
|   ||||| ||.  ||.| |  ||       . |. .  |.. |  |  |  |..  .|.||||. ||  |
GHTKAVDWWTLGIVMYEMLFGCPPYY---GNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKR
Kinase YANK1.AA Ciliate-E2 23-281 21 1.2e-68 234.43 In-house 1-365 (365) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)

FEILRAIGKGSFGKVCIVRKNDTKKM-----------------------YAMKYMNKQKCVERNEVRNVF----------KELQIMQGLEHPFLVNLWYS
..... ||.|.||.|. ...  ..|.                       ||||.|.|..  . . . ...          .|..|.. | ||..... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DEEDMFMVVDLLLGGDLRYHLQQN-----------VHFQEDTVKLFICELA---------------MALDYLQSQR-IIHRDMKPDNILLDEHGHV
||  |.. ...| ... ||||......|             | |  .| .. ...                || || |.  ||||| ||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

HITDFNIAA----------------MLPKET-----------------RITTVAGTKPYMAPEMFTSRK------ETGYSFAVDWWSLGVTAYELLRGRR
 |.|| ..                 ...                     . |..|| .|||||.. . |      ..||....|.|||||. ||.| |..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYHIRSSTSSKEIVNMFETAIVTYPSA------------------WSQEMVSLLKK----LLEPNPDQRFSHLTDIQNFPYM
|.            .  .   . .|..                  ||||.  |.||    .|. .|..|..   .| | |..
PF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase YANK1.AA AktR 23-268 37 6.6e-66 225.28 In-house 1-251 (268) Show / Hide 
Range on Protein: 23-268
Range on HMM: 1-251/268
Sequence Identity: 37% (95 aa)

FEILRAIGKGSFGKVCIVRKN-DTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQ-GLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQE
|.... .||| ||||  |.|. |..|.||||   |.| .|||  . .  | .||.    |||.|.| |.||..|  | . .   ||.| .||... .| |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DTVKLFICELAMALDYLQSQ-RIIHRDMKPDNILLDEHGHVHITDFNIAA---MLPKETRITTVAGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYEL
.... ....   ||.|| ..  || ||.||.||||||.||| ||||  .    |  .. . ... ||  |||||| |     |. ..||||..|.  ||.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKK--KGHNKSVDWWAFGIFIYEM

LRGRRPYHIRSSTSSKEIVNMFETAI---VTYPSAWSQEMVSLLK-KLLEPNPDQR
. |  |     . . .... .. .     ..|||  |..  .|.. |||  || .|
VTGCPPF---YHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKR
Kinase YANK1.AA Ciliate-E2-Unclassified 23-278 24 2.1e-64 220.28 In-house 1-352 (352) Show / Hide 
Range on Protein: 23-278
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNV---------FKELQ-------------IMQGLEHPFLVNLWYSFQDEEDMFMVV
..|.. ||.|.||||. ......|. ||||||.|.. . .. ..|.          ....             |.. . |||.|.. | |||.. ...| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DLLLGGDLRYHLQQN-----------------VHFQEDTVK-----LFICELAMALDYLQSQ-RIIHRDMKPDNILLDEHG---HVHITDFNIAA-----
... ||||.......                  .|.|  .|      .. ..  .|.|| ..  ||||| ||.|||.|. |   .. |.|| |.      
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------MLPKETRITTVAGTKPYM----APEMFTSRKETGYS--FAVDWWSLGVTAYELLRGRRPYHIRSSTS----------------SKEIVN
             .|. ...|..||  ||    |||..  ... . |  ...|.||||| .||.| |..|.  .....                 ... .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ-GQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

MFETAIVTYPS-----AWSQEMVSLLK----KLLEPNPDQR--FSHLTDIQNF
  .. .  .|       ||.|   ...    |.|. ||..|  |. .   . |
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase YANK1.AA RSK 23-281 33 1.2e-62 214.41 In-house 1-271 (271) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-271/271
Sequence Identity: 33% (95 aa)

FEILRAIGKGSFGKVCIVRKN---DTKKMYAMKYMNKQKCVER-----NEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQ
.|... ||.|||.|| ...|    ||.. ||||   | . . .      |.|.      |.    ||| | | |.||||.  .|. |.. ||||  .|. 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERI------ILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLK

NVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEH----GHVHITDFNIAAMLPKETR-ITTVAGTKPYMAPEMFTSRKETGYSFAVDWWSL
 . | |. ||   .|.| |..|| || |.||| ||.|||.|..    ||. |.||  |  |  |.    |  .|  |||||.   .   |.. |.||||.
QKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQ---GHDQACDWWSF

GVTAYELLRGRRPYHIRSSTSSKEIVNMFETAI----VTYPSAWSQEMVSLLKKLLEPNPDQRFSH----LTDIQNFPYM
||  || | |. |.. .   . ..|      ..      ...  |.|  .|| ..|. .| .| .       .| . |. 
GVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase YANK1.AA TyrKc 23-278 21 3.2e-16 39.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-278
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGL--EHPFLVNLWYSFQDE-------EDMFMVVDLLLGGDLRYHLQ
 . .. .| | ||.|.  . .    . | | ... .      ..   .|..||  |  .|| .|.|     ..       | ...|. .  .|||. .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNVH-FQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKE------TRITTVA---GTKP-----YMAPEMFTSRKET
 . . .. ..   |    |   .|| |...||||    |.|..| ..| |.||  .  .  .      .   ...   |.|       |||| .   .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYG

GYSFAVDWWSLGVTAYELL-RGRRPYHI---RSSTSSKEIVNMFETAIVTYPSAW---------SQEMVSLLKKLLEPNPDQR--FSHLTDIQNF
 .... | || ||. .|.. .|  ||     .   | .|...  ..     . .          ..|| .. |.  . .|..|  || .  .. |
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase YANK1.AA Pkinase_Tyr 23-223 24 1.8e-15 53.01 Pfam 1-216 (270) Show / Hide 
Range on Protein: 23-223
Range on HMM: 1-216/270
Sequence Identity: 24% (55 aa)

FEILRAIGKGSFGKVCIVRKN----DTKKMYAMKYMNKQKCVERN-EVRNVFKELQIMQGL-EHPFLVNLWYSFQ-DEED--MFMVVDLLLGGDLRYHLQ
 .... .|.|.||.|.  . .    .||   | | . |... ...   .  ..|..||  |  || .|.|      ..|   ...|. .  .|||. .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----NVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAML-PKETRITTVAG----TKPYMAPEMFTSRKETGYSFAV
.    . ..   .   .  . |....|| |...||||    |.|..| ..| |.||  |  . ....  ....|      . |||| .  .|   .. . 
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK---FTTKS

DWWSLGVTAYELLR-GRRP-Y
| || ||. .|..  |. | |
DVWSFGVLMWEIFTYGEQPTY