Gene air-1 (Nematode worm)

air-1

Species: Nematode worm
Alias: CE21025, K07C11.2, aSWK208, air-1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 8224008-8226120, WormBase Genetic Map location: V:1.30539,

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
air-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 253 Kinase domain by global Sugen HMM Fasta, JSON
air-1.AA Protein Genbank 326 None Fasta, JSON

Protein domain

Protein domains of air-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase air-1.AA Aur 44-296 51 2.4e-220 588.58 In-house 1-257 (257) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-257/257
Sequence Identity: 51% (133 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNE
|..|.||||||||||. .|.|||. |.||||.||.|. . .. |||.|||.||.||.||||| .|||||||.|.. ||.||..|||...||.|| .. .|
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

VIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLD-SKLNLKLADFGWSVVAD-HSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAP
 .| ....|..|||.|||||..|||||||||.||| .. |.|..||||||... ...|.|.|||.||..||||..|.||..||||..|.|..|...|..|
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FAN-QTGDKLIARIK-ECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWI
|.. .. |. . ||| ...|..|| ....|  ||. | ...|..|..|..||.||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase air-1.AA S_TKc 44-296 31 3e-96 326.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASR--GELFNVLQSQPGHK-
....|..||| || |.  |.|||.|| |.|..            ...|||.|  . .|||| .||..|.| ........|..   |.|| .......|. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQPHDF-NVDIWAIGILLFEML
    .|  | ....|...|| ||||.|.||||.||||.|||.  ..|..||| . .      .|.||| .|.|||..   ....  .|.|..|..|.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMA-------HPWI
.|| ||   . .... .|.          .. | ..|. . .|.|..|.   ....       |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase air-1.AA AGC 44-296 21 1e-94 244.67 In-house 1-395 (395) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-395/395
Sequence Identity: 21% (87 aa)

FDVGRPLGKGKFGNVFISREK------KTKRIIALKVLFKTQ-LLQLG--VSHQLKRE------------IEIQYHLR----------HPNILT-LYGYF
|.. ...||| || |.  |.|       |... |.||| |    ...     .. ..|             .|  ...          ||.|   |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HDDKR--VFVILDYAS---------RG-ELFNVLQSQ-PGHKVNEVIAGRFVRQ-------LANALHYCHS-KGVIHRD-IKPENLLLDSKLNLKLADFG
.|...  .. ...|..          | |||  || .    . .|  |  .  .       .. ||.| || .|.|||| .||||.|||.. ..||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVVADHS----------------------------------------------------KRHTLCG--TMDYLAPEMVSNQPHDFNVDIWA--IGILLF
 . .   .                                                    . .|.||  | .|.|||..    ... .|.|.   |.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLVGYAPFANQTGD----------KLIARIK------ECKIYIP----------SVVTDGAASLINAIIKKEPQERLP----------LVDIMAHPWI
|||.|| || ... .          ..  .|.      ..|. .|          . ... | .||.  ..|.| .||             .|..||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase air-1.AA CAMK 49-296 21 4.6e-89 287.07 In-house 1-425 (425) Show / Hide 
Range on Protein: 49-296
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

PLGKGKFGNVFISREKKTK------------RIIALKVLFKTQLL-------------------------QLGVSHQLKREIEIQYH-------LRHPNI
 ||.| || |.  ..|.|.            .  | |.. |..|                          .    ....|||||  .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LTLYGYFHD-------------------DKRVFVIL---DYASRGEL----FNVLQSQPG-------------HKVNEVIAGRFVRQLANALHYCHSKGV
. || .. |                   ||... ..   .|.| |||    |. ......             ....|  | |..||.. |.|||||...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLLLDSK-----------------LNLKLADFGWSVVADHSK-------------------------RHTLCGTMDYLA-PEMVSN------
.|||.||||.|||..                  |.|..||| . . |...                          .| |||  | | ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QPHDFNVDIWAIGILLFEMLVGYAPFANQ-------------TGDKLIARIKECKIY-IPSV---------------VTDG--------AAS
        ..... .|.|..|..|. ||.|| ||                .  .|  .|...| . .|.                ..|         . .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINAIIKKEPQERLPLVDIMAHPWI
||. . ...|..|. . ....|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase air-1.AA CAMKL 44-296 30 1.3e-88 282.9 In-house 1-297 (297) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-297/297
Sequence Identity: 30% (90 aa)

FDVGRPLGKGKFGNVFISRE-KKTKRIIALKVLFKTQLLQLGVSHQ------------LKREIEIQYHLR---HPNILTLYGYFHDDKR------VFVIL
...|. |||| || |   .  . |..  | |.. |  .    ....            ..|||.|. .|.   ||||  ||  . ...       .. ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DYASRGE--LFNVLQSQPGHK--VNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKL--NLKLADFGWS-----V-VADHSKRHTLCGTMDYL
 |.| ||  ||. ........    |  | |. ||.  |..||||.|..||||||||.|||..   |.|..||| |     . . .  | .| ||.  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEMVSN--QPHD-FNVDIWAIGILLFEMLVGYAPFA----------NQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWI
|||...   .|.| . ||||..|..|. |..|| ||           |.   ... ..  ... |.. |   . .||  . .. | .|  . .|| ||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase air-1.AA MARK 44-296 35 9.2e-82 267.05 In-house 1-262 (262) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFH--DDKR-VFVILDYASRGELFNVLQSQPGHK
. ... .|.| .. |   . |.|.|  |.|.. |..|        ..|||||  .| ||||  |. ..   . .. ...|..|||.|||.. ....|...
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKL--NLKLADFGWSVVADHSK-RHTLCGTMDYLAPEMVSNQPHD-FNVDIWAIGILLFEML
  |  | |. ||.  |..|||||...||||||||.|.|..   | |..|||.|.     .   | |||  | |||... .| | . ||||. |..|. |.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGYAPFANQT--GDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWI
.|| || ..|    .|  .|  .|  ||. | ... .||. ...  | ||  . .|| |||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase air-1.AA Pkinase 44-296 28 1.9e-79 275.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-293/293
Sequence Identity: 28% (83 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLK-REIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRG----ELFNVLQSQPG
. .||..|.| || |.. ..|.| .| |.|.. |         . .. .||.|  .|.||||..||..|.|.... ....|.  |    .|| ... . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HKV--NEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNL----KLADFGWSV---VADHSKRHTLCGTMDYLAPEMVS-NQPHDFNVDIWAI
 ..   |  . ....|.. .| ||||.|.||||.||||.|.|.. ..    |..||| .        |  .|.||| .|.||| .  .|...  ||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLFEMLVGYAPFANQ------TGDKLIARIKECKIYIPSVVT---------------------DGAASLINAIIKKEPQERLPLVDIMAHPWI
|..|.||| |. || ..      . ...|.||.....  ..  .                     . . ..|. ...| |..|.   .|. |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase air-1.AA AMPK 44-296 35 6.8e-76 224.81 In-house 1-254 (254) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-254/254
Sequence Identity: 35% (91 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYF-HDDKRVFVILDYASRGELFNVLQSQPGHKVN
. .|  .|.| || | .   . |.   |.|.| |. . .. ..  ..|||.|   .|||.|  ||       .  |... |.| |||| .  .    ...
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ

EVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS-VVADHSKRHTLCGTMDYLAPEMVSNQPHD-FNVDIWAIGILLFEMLVGYA
|  | ||  |  ... |||  .. ||| |||||||| . |.|..||| | .  |  .  | ||   | ||||.|...     ||||  |. |. || || 
EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWI
||  .   .| ..||... |||. ... |..||. . .. |..|.   ||..||| 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase air-1.AA PLK 44-296 29 4.8e-70 227.31 In-house 1-258 (258) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-258/258
Sequence Identity: 29% (77 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNE
. .|..|||| |  ..  .. .||...| ||  |  .   .    .|.||||.  |.||||. .. .| |.  |.. | |.....|. ..     ....|
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRR-AKRLTE

VIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADH--SKRHTLCGTMDYLAPEMV--SNQPHDFNVDIWAIGILLFEMLVGY
  . ....|....| | |....||||.|. ||.|......|..||| ..  ..   ...|.|||  | ||| .  ..|.|.. ||.|..|. .  .|.| 
PEVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGK

APFANQTGDKLIARIKECKIYIPSV--VTDGAASLINAIIKKEPQERLPLVDIMAHPWI
 ||  ..      |||...  .|.   . | |..||...... |.||. .  |. ||. 
PPFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase air-1.AA Ciliate-E2 44-296 23 6.8e-69 235.2 In-house 1-365 (365) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

FDVGRPLGKGKFGNVFISREKKTKR-----------------------IIALKVLFKTQLLQLG-VSHQLK---------REIEIQYHLRHPNILTLYGY
... . .|.| || |.  . .|...                       |.|.|.. | |. |.  . |...          | .|. .| ||||. .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FH--DDKRVFVILDYASRGELFNVLQSQ---PGHKVN------EVIAGRFVRQLAN---------------ALHYCHSKG-VIHRDIKPENLLLDSKLNL
|   ||. .. ...|.. |.||  ....    .|. .      |  .... .|...               ||.|.|||. .|||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGWSVVADHSKR---------------------------------HTLCGTMDYLAPEMVSNQP---------HDFNVDIWAIGILLFEMLVGYAP
|..||| |  .| .                                   .|.|||  |.|||......         .|. .|||..|..|.||| |. |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FANQTGDKLIARIKECKIYIPSV------------------VTDGAASLINA----IIKKEPQERLP-LVDIMAHPWI
|        .  ||.||| .|.                   ... .  ||.     ...|.|..|.    .|. |||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase air-1.AA RSK 47-296 31 1.2e-68 234.33 In-house 1-278 (278) Show / Hide 
Range on Protein: 47-296
Range on HMM: 1-278/278
Sequence Identity: 31% (88 aa)

GRPLGKGKFGNVFISREK---KTKRIIALKVLFKTQLLQLGV-SHQLKREIEIQYHLR-HPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHK-
 . ||.| .| ||. |..   .|..| | ||| |  . |  .     ..|..|  . . ||.| ||.  |.... .. |..| . ||||  || . .|. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKE-KHFG

-VNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDS---KLNLKLADFGWSVV--AD-HSKRHTLCGTMDYLAPEMVS---NQP-HDFNVDIWAIG
   |  |    .... |. . |..|.||||.|||| |.|.      .|| ||| .    .|  .. .| |.| .|.||||.     |  || ..|.|  |
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

ILLFEMLVGYAPFAN---QTGDKLIARIKECK--IYIP--SVVTDGAASLINAIIKKEPQERLP-----LVDIMAHPWI
.|..|||.|. ||..   .. .....||...|    .|  . ... | .||..  ...|. ||      . .| .|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase air-1.AA Ciliate-E2-Unclassified 44-296 22 2.7e-66 226.58 In-house 1-352 (352) Show / Hide 
Range on Protein: 44-296
Range on HMM: 1-352/352
Sequence Identity: 22% (81 aa)

FDVGRPLGKGKFGNVFISREKKTKRII-----ALKVLFKTQLLQLGVSHQLKRE-IEIQYH------------------LRHPNILTLYGYFHDDKRVFV
. ... .|.| || |.  ..||.|  .     . |.  . |.... .  ....| .|.. .                  . ||.|. .. .| |.. .. 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILDYASRGELFNVLQSQPG---------------HKVNEVIAG-----RFVRQLANALHYCHSKG-VIHRDIKPENLLLDSKL---NLKLADFGWSV---
...|.  |.|.. ......               ... |  |      .. .|. ..| |.|.|. .|||||||||.|.|..    ..|..||| |    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------VADHSKRHTLCGTMDYL----APEMVSNQPHD----FNVDIWAIGILLFEMLVGYAPFANQTGDK----------------LIARI
              . .. . .| |||  |.    |||.  .| .|    . .|||. |..|.||| || ||  .. ..                |.  |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KECKIYIPS--------VVTDGAASLIN----AIIKKEPQERLPLVDIMAHPWI
|...|..|.         . . |. .||     ..|| | .|. . .|. |||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase air-1.AA TyrKc 44-299 21 1.4e-16 45.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 44-299
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHL--RHPNILTLYGYFHDD-------KRVFVILDYASRGELFNVLQ
   |. || | || |.  . |   .  | |.| .           . ||..|  .|  .||||. |||.  ..       . ..... |.. | | . |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHS------KRHTLC----GTMD-----YLAPEMVSNQPH
.  .. ..      |  | |.   | |||..||||.   | |.....  | .||| |   ..       |         |. .      .|||       
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DFNVDIWAIGILLFEML-VGYAPFAN-----QTGDKLIARIKEC-KIYIPSV--------VTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEM
 .  |.|. |....|..  |  |  .      . . .|...|.     .|           .|   ...    . .| .|    .|     ....
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase air-1.AA Pkinase_Tyr 44-189 27 6.7e-16 54.48 Pfam 1-156 (270) Show / Hide 
Range on Protein: 44-189
Range on HMM: 1-156/270
Sequence Identity: 27% (43 aa)

FDVGRPLGKGKFGNVFISREK----KTKRIIALKVL--FKTQL-LQLGVSHQLKREIEIQYHL-RHPNILTLYGYFH-DDKR--VFVILDYASRGELFNV
   |. ||.| ||.|.  . |    .||   | |.|    ..  .    .  . ||..|  .| .||||. |||    ...   ..... |.  | | . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LQSQ--PGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFG
|...  ......      . .| |... | .||. ||||.   | |.....  | .|||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase air-1.AA Pkinase_Tyr 224-256 22 1.25472 2.75 Pfam 196-231 (270) Show / Hide 
Range on Protein: 224-256
Range on HMM: 196-231/270
Sequence Identity: 22% (8 aa)

DIWAIGILLFEMLV-GYAP-FANQTGDKLIARI-KE
|.|. |.|..|..  |  | ... .   ....| ..
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED