Gene B0207.7 (Nematode worm)
B0207.7
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| B0207.7.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 264 | Kinase domain by global Sugen HMM | Fasta, JSON |
| B0207.7.AA | Protein | Genbank | 373 | None | Fasta, JSON |
Protein domains of B0207.7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | B0207.7.AA | TTBKL | 21-284 | 32 | 3.1e-119 | 402.4 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 21-284 Range on HMM: 1-288/288 Sequence Identity: 32% (94 aa) FEIIKKLGSGGFGAVYQVRKNG--FDMALKTEFVDTESDDTLKNEAHILRLLQWSPGFCRLYTAKRLTWNKQQVNIMAMSLCARPISRLRRMMPDKH-FS ..|.|..|.||||.||.|. . |.| . | ........ . . .. |....|. .. . . . ..... | |.|.|| . .. ||.||| |. || WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS KSTAARLSVQLLEALRDMHASGIIHRDVKGSNCGWHAS------SRRILLFDLGFSRKYLELDPST------NTMRHRAARK---TPGFMGTSNYCSTYA ..|..|...|.|.||..|| |.|||||| .|| |... .|...|.| |..|.|.. |... |....|..|. ...|.|| .|||... DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM HDECDQGRRDDLWAWLYSTVEMFLGSLPWNNED-KTILVSKMKKKIGKKLFFK------CPREIALMYEHIRQLKFDSTPDYQMMLNHF || ..||| ||||.|.|...|...| |||.|.. | ......|......|| . ||.| . ...|.|.|.. ..|||.|....| HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | B0207.7.AA | CK1 | 21-280 | 26 | 5.6e-88 | 298.6 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 21-280 Range on HMM: 1-339/339 Sequence Identity: 26% (90 aa) FEIIKKLGSGGFG-AVYQV------RKNG------FDMALKTEFVDTESDDTLKNEAHILRLLQW-----------SPGFCR------LYTAKRLTWNKQ ....||.|.|||| ..| | .... ..|.|.| .... . .. |.... .. . ...|| . ... WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED QVN-IMAMSLCARPISRLRR--MMPDKHFSKSTAARLSVQLLEALRDMHASGIIHRDVK------GSNCG---------WHASSRRILLFDLGFSR-KYL . . .| |.|. . ...||. .|....||..|. .. .|.||||..|| |.||||.| | |.. |. .|.. ..| |..| ||. DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR ELDPST-------NTMRHRAARK---TPGFMG-TSNYCSTYAHDECDQGRRDDLWAWLYSTVEMFLGS--LPWNNEDKTIL-----VSKMKKKIGKKLFF . | . .|..|| .|. . ||.| | ||| .|. ..||||||||.|.| .|.. |. ||| | .. | |||... .. . DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM K-------------CPREIALMYEHIRQLKFDSTPDYQMM . ||.| ....||.||....|||.| STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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| Kinase | B0207.7.AA | TTBK | 21-280 | 34 | 1.5e-43 | 150.97 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 21-280 Range on HMM: 1-257/257 Sequence Identity: 34% (92 aa) FEIIKKLGSGGFGAVYQVRKNGFD---MALKTEFVDTESDDTLKNEAHILRLLQWSPGFCRLYTAKRLTWNKQQVNIMAMSLCARPISRLRRMMPDKHFS ..|| | |||| .|. . |.| | ... || | .|. || . || .. | . | | |.| . . ||| |. || WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQP-KQVLKMEVAVLKKLQGCDHVCRFIGCGR----NDKFNYMVMQLQGKNLADLRRKQPRGCFS KSTAARLSVQLLEALRDMHASGIIHRDVKGSN--CGWHASSRRIL-LFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRRDDL ||. || ||.|.... | | |||.| || | .| .|. . | | |.|. . . |..|. || || | | || . ||.||| LSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYT-----NACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDL WAWLYSTVEMFLGSLPWNN-EDKTILVSKMKKKIGKKLFFK-CPREIALMYEHIRQLKFDSTPDYQMM | | || | ||| || | .||.| .. | || |. . .||. |.. .||||.. WSLFYMLVEFVQGQLPWRKIKDKDQ-VGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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| Kinase | B0207.7.AA | Worm6 | 105-280 | 32 | 2.9e-35 | 123.5 | In-house | 90-279 (279) | Show / Hide |
Range on Protein: 105-280 Range on HMM: 90-279/279 Sequence Identity: 32% (63 aa) SRLRRMMPDKHFSKSTAARLSVQLLEALRDMHASGIIHRDVKGSN--CGW-----HASSRRILLFDLGFSR--KYLELDPSTNTMR-HRAARKTPGFMGT ..||. ||..|| .|. ... | |||..|.| | |||||| .| .| ...| ..| |..| ||.. . . | | ... ||.|| WDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTAC-----GFRGT SNYCSTYAHDECDQGRRDDLWAWLYSTVEMFLGSLPWNNEDKTILVSKMKKK----IG---KKLFFK-CPR-EIALMYEHIRQLKFDSTPDYQMM |.. .|. ..|.|.||. |.| |||..| ||| . ... | | ||. . ...||. ||. | . | |... ..|||. VRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | B0207.7.AA | CK1-A | 21-280 | 27 | 1.1e-22 | 76.84 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 21-280 Range on HMM: 1-261/261 Sequence Identity: 27% (75 aa) FEIIKKLGSGGFGAVYQV--RKNGFDMALKTEFVDTESDDTLKNEAHILRLLQWSPGFCRLYTAKRLTWNKQQVNIMAMSLCARPISRLRRMMPDKHFSK . ...|.||| || .| .|| ..|.| | . | || . |.|| .|. .. | . .. |.| | | . | . ...|. YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQ-LIYEAKVYRILQGCVGIPHM----RWYGCEKDYNVMVMDLLGPSLEDLFNFC-KRRFTM STAARLSVQLLEALRDMHASGIIHRDVKGSN--CGWHASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRRDDLWA | | |.. . .| . ||||.| | | .. | | | ..|| . .| .| |. .|| | | || .| ||||. . KTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRD----SRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMES WLYSTVEMFLGSLPW------NNEDK--TILVSKMKKKIGKKLFFKCPREIALMYEHIRQLKFDSTPDYQMM | . .|.||| . . | |. || | ..| | | ... ...|.|.|. .||| . MGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPI-EQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | B0207.7.AA | Dual | 114-284 | 26 | 1.5e-19 | 62.34 | In-house | 108-282 (282) | Show / Hide |
Range on Protein: 114-284 Range on HMM: 108-282/282 Sequence Identity: 26% (48 aa) KHFSKSTAARLSVQLLEALRDMHASGIIHRDVKGSN--CGWHASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRR . .|.... | |.|..| | | .||..| .| || . . . | . |||.. |. . ||.|||. . |. | . . |||| GQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYID--PE--NKKHRTARKKVKMYGCGRYACRACMMQKDQGRK DDLWAWLYSTVEMF-LGS-LPWNNEDKTILVSKMK----KKIGKKLFFKCPREIALMYEHIRQLKFDSTPDYQMMLNHF ||| .| | .. .. ..| .| . | | .|. . . ||. . . . . .|||||| ..| DDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL |
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| Kinase | B0207.7.AA | CK1-D | 21-280 | 26 | 6.3e-19 | 63.29 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 21-280 Range on HMM: 1-261/261 Sequence Identity: 26% (72 aa) FEIIKKLGSGGFGAVY--QVRKNGFDMALKTEFVDTESDDTLKNEAHILRLLQWSPGFCRLYTAKRLTWNKQQVNIMAMSLCARPISRLRRMMPDKHFSK . | .|.||| || .| . ... ..|.| | . |. |. |... ...| | .. | . . |.| | | . | ...|| YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTK-HPQLHIESKFYKMMQGGIGIPEI----RWCGQEGDYNVMVMDLLGPSLEDLFNYC-HRKFSL STAARLSVQLLEALRDMHASGIIHRDVKGSN--CGWHASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRRDDLWA | |. |.. . .|. ||||.| | | . . | | ...| . ..| .| . | || | | | .| ||||| . KTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRD----ARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLES WLYSTVEMFLGSLPWNNEDKTILVSKMKKKIGKKLFFKC-------PREIALMYEHIRQLKFDSTPDYQMM | . .||||| . | . . ||. | | | . .. |.|||| ||| . LGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | B0207.7.AA | CK1-Unique | 95-231 | 23 | 1.4e-16 | 54.03 | In-house | 87-232 (337) | Show / Hide |
Range on Protein: 95-231 Range on HMM: 87-232/337 Sequence Identity: 23% (35 aa) MAMSLCARPISRLRRMMPDKHFSKS------TAARLSVQLLEALRDMHASGIIHRDVKGSNCGWHASS----RRILLFDLGFSRKYLELDPSTNTMRHRA . | . ... ...|| | .. .| ... | |.... || | .||. | | | | . . |.| .|. . .... | IVMTMHGPSMEECCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNN---HQIRQ ARKTPGFMGTSNYCSTYAHDECDQGRRDDLWAWLYSTVEMFLGS--LPW |.. | |. ||. | . ..|||||. |.|. . ... | | PRPITPFRGCKDYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSW |
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| Kinase | B0207.7.AA | Pkinase | 21-150 | 25 | 1.3e-13 | 49.16 | Pfam | 1-139 (293) | Show / Hide |
Range on Protein: 21-150 Range on HMM: 1-139/293 Sequence Identity: 25% (37 aa) FEIIKKLGSGGFGAVYQVRKNGFD--MALKTEFVDTESDDTLKN-----EAHILRLLQWSPGFCRLYTAKRLTWNKQQVNIMAMSLCARP---ISRLRRM ..|..|.|||.|| ||. .. | |.|. ...|... ... |..|.. |. .| .||| . . . | | .| .. ... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYI M--PDKHF--SKSTAARLSVQLLEALRDMHASGIIHRDVKGSNC . .. | | .. . |.|..| .|. ||||||.| .|. STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI |
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| Kinase | B0207.7.AA | CK1 | 21-214 | 24 | 2.1e-13 | 42.71 | In-house | 1-199 (271) | Show / Hide |
Range on Protein: 21-214 Range on HMM: 1-199/271 Sequence Identity: 24% (52 aa) FEIIKKLGSGGFGAVYQVRKNGFDM-----ALKTEFVDTESDDTLKNEAHILRLLQW------SPGFCRLYTAKRLTWNKQQ--VNIMAMSLCARPISRL .....|.|.| || .|.. .. | | | ... |. || |.. || ..|. ..|. . .| ||| |.| . | YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHP-QLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQE----EQGDYNIMVMDLLGPSLEDL RRMMPDKHFSKSTAARLSVQLLEALRDMHASGIIHRDVKGSN--CGW-HASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHD .. ...|| | . |... . .| ..||||.| | | . .. . | |.. .|. .| .| | .. || | | .| FNFC-NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYR----DDKTHQHIPYRENKNLTGTARYASINTHL ECDQGRRDDL |.||||. GIEQSRRDDM |
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| Kinase | B0207.7.AA | S_TKc | 21-302 | 18 | 1.7e-12 | 6.35 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 21-302
Range on HMM: 1-231/231
Sequence Identity: 18% (57 aa)
FEIIKKLGSGGFGAVYQVRKNG--FDMALKTEFVDTESDDTLKNEAHILRLLQWSPGFCRLYTAKRLTWNKQQVNIMAMSLCAR---PISRLRRMMPDKH
.||..|.|.|.|| ||..|... .|.| .....| ||. | ..|| . . . | | .| .. . .. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----FSKSTAARLSVQLLEALRDMHASGIIHRDVKGSNCGWHASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRR
|. .|... |...|| .| ||||||.| .| .| . | |..|.. | || .|..
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------------------TTFCGTPWYMAPEVL--------
DDLWAWLYST------------VEMFLGSLPWNNEDKTILVSKMKKKIGKKLFFKCPREIALMYEHIRQLKFDSTPDYQMMLNHFQ-QMYARLEIDESEP
|.. ||. | |. . .| |||| | . ... . .| |. . |
------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
-------MDFE
. .
DEWDIKCHPWF
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| Kinase | B0207.7.AA | CK1-Unclassified | 21-99 | 26 | 8.9e-12 | 31.05 | In-house | 1-85 (244) | Show / Hide |
Range on Protein: 21-99 Range on HMM: 1-85/244 Sequence Identity: 26% (24 aa) FEIIKKLGSGGFGAVYQVRKNGFDM------ALKTEFVDTESDDTLKNEAHILRLLQWSP-------GFCRLYTAKRLTWNKQQVNIMAMSL ...|.|.|.| || .|.. .| |.| | ... ..|. || |.. || |. ..|. . ... ||| |.| YRVIEKIGQGSFGEIYKC----INMQTNEEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQE--EQGDYNIMVMDL |
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| Kinase | B0207.7.AA | Worm6 | 21-79 | 30 | 3.2e-10 | 33.19 | In-house | 1-66 (279) | Show / Hide |
Range on Protein: 21-79 Range on HMM: 1-66/279 Sequence Identity: 30% (20 aa) FEIIKKLGSGGFGAVYQVRKNGFD----MALKTEF-VDTESDDTLKNEAHILRLL--QWSPGFCRL ... ||.|.|||||||.| . |.| | . ... || |. .| .. . ...||.. WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKI |
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| Kinase | B0207.7.AA | CK1-Unclassified | 127-214 | 30 | 1e-05 | 12.85 | In-house | 112-199 (244) | Show / Hide |
Range on Protein: 127-214 Range on HMM: 112-199/244 Sequence Identity: 30% (28 aa) QLLEALRDMHASGIIHRDVKGSN--CG-WHASSRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRRDDL |... . .| ..|||| | | | . .. . |.|.| .|. .| .| | .. || | | || |.||||| QMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDM---DKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL |
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| Kinase | B0207.7.AA | Dual | 21-61 | 30 | 1.5e-05 | 14.45 | In-house | 1-42 (282) | Show / Hide |
Range on Protein: 21-61 Range on HMM: 1-42/282 Sequence Identity: 30% (13 aa) FEIIKKLGSGGFGAVYQVRKNGFDMALKTEFV-DTESDDTLK ... ||||||. ||.|.. . .. .. .|||.. | WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEK |
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| Kinase | B0207.7.AA | CK1-Unique | 21-38 | 44 | 0.000107 | 12.25 | In-house | 1-18 (337) | Show / Hide |
Range on Protein: 21-38 Range on HMM: 1-18/337 Sequence Identity: 44% (8 aa) FEIIKKLGSGGFGAVYQV . .||..|.||.| |. | WCVIKHIGYGGYGCVHRV |
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| Kinase | B0207.7.AA | CK1 | 255-278 | 41 | 0.000283 | 10.85 | In-house | 248-271 (271) | Show / Hide |
Range on Protein: 255-278 Range on HMM: 248-271/271 Sequence Identity: 41% (10 aa) CPREIALMYEHIRQLKFDSTPDYQ .| | | ...|||.|. .|||. FPNEFAMYLNYCRQLHFEEKPDYM |
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