Gene B0285.1 (Nematode worm)

B0285.1

Species: Nematode worm
Alias: aSWK166, B0285.1, CE31401, CDK2_CAEEL
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: III: 4328905-4335972, WormBase Genetic Map location: III:-3.79,

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7

Sequence

Name Sequence Type Origin Length Description Download
B0285.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 293 Kinase domain by global Sugen HMM Fasta, JSON
B0285.1.AA Protein Genbank 684 None Fasta, JSON

Protein domain

Protein domains of B0285.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase B0285.1.AA CRK7 311-605 57 1.8e-229 768.65 In-house 1-343 (343) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-343/343
Sequence Identity: 57% (198 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENE---KEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGL
| |..|||||||||||||.|. |||.||||.||..||   ||||||||||||||||||.|.|||.|..||.|.....|.|.....||.||||.||||.||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKES--RLYTNRVITLWYRPPELLLGDERY--------
|||||...|...|.....||||||..|.|...||||||||||||.||.||.||||.|||||...|.  | ||||||||||||||||||.|||        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------GPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIR
                              ||.||.||.||.||||||.||.|.||||..|||.|.|.|||||..||||...|..|||...||.|.||.|
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

EEFEH-----IMPREAVDLLDKMLTLNPEKRISAKEALNHPWI
|||.|     .||.|..|||||||.|.|.||..|.|.|.|.|.
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase B0285.1.AA CDK 311-605 43 5.4e-167 538.47 In-house 1-284 (284) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-284/284
Sequence Identity: 43% (140 aa)

YTMLDQIGEGTYGQVYKAVNNLTG-----EQVALKRVRLEN-----EKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTR--ANFYLVFE
| .|..|||||||.|||| . .||     . ||||..|.||     |||||||||||||..|..| |.|||.|.|..... ....  ...   ..|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGE-----LKIADLGLARLWEK------ESRLYTNRVITLWYRP
|.|||| ....           | ....|||.||.|.|  ...|||.|..|||.||.||     ||||| ||||..        ..| ||..|.|||||.
YMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRA

PELLLGDERYG--PAIDVWSTGCMLGELFT---RKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIREEFEHIMPREAVDLL
||||||...|.  ..||.|| || ..|.||   ||||| |..|  ||..|...||.|. ||||..|.| ..                          |||
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLL

DKMLTLNPEKRISAKEALNHPWI
.|||...|.|||||..||.||. 
NKMLCYDPKKRISAEQALQHPYF
Kinase B0285.1.AA CMGC 311-605 25 6.00000000001e-138 456.35 In-house 1-513 (513) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-513/513
Sequence Identity: 25% (130 aa)

YTMLDQIGEGTYGQVYKAVNNLTG--------------EQVALKRVRLEN---------EKEGFPITAIREIKILRQL-----------------HHKNI
|. ...|||||||.|||.....|.              |.||.|.....          ||.||||.|.||||||..|                 ||.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VRLMDIVIDDISMDELKRTR-------ANFYLVFEYVDHDLIGLLESKE-------LVDFNKDQ------------ICSLF------KQLLEGLA--YIH
|.| ||. .. |  ......        ..||||||.|||| ......         . ..  .            |....      .|.|.||.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

NTG--FLHRDIKCSNILVNNKGEL--------------------KIADLGLARLWEKE---------------------SRLYTNRVITLWYRPPELLLG
  .  ..|||.| .|||.|...||                    ||.| ||||  ...                     .| ||..| |.|||.||.|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

D---------ERYGPAIDVWSTGCMLGELFTR--------KPLFNGNNE-----------FGQLELISKVCGSPN---------------VDNWPELTEL
.           |...||.|| ||...|..|.        |||| |..|             ||..| ||.|.|.                ..||. ..|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

VGWNTFR-------------------------MKRTYQRRIREEFEHIMP----------------------------------REAVDLLDKMLTLNPE
 ..|.|                           .. . . ... |  . .                                   .|.|||.|||...|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRISAKEALNHPWI
|||.|..||.||..
KRITAEQALQHPYF
Kinase B0285.1.AA CDC2 311-605 40 1.5e-123 381.72 In-house 1-301 (301) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-301/301
Sequence Identity: 40% (126 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEG--FPITAIREIKILRQLH-HKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGL
|. .  ||||||| |||. .. |...||||..|||.| ||  .| |||||| .|  |  |.|||.| |...             . |.||||.|.||  .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----------NKLYMVFEYLDMDLKKY

LE-SKEL-VDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYT--NRVITLWYRPPELLLGDERYGPAIDV
.. |.     .  . . |...|.|.|... |  . .|||.| .|||...||..|||| ||||     .| ||    |.|||||.||.|||..||  ..|.
MDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDM

WSTGCMLGEL---FTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELV-------GWNTFRMKRTYQR-RIREEFEHIMPREAVDLLDKMLTLNPEK
|| || . |.    |.|||| |  |  ||  | .. |.|| ..||..|.|         |..  ...   .     ..  ... |..|||..|| ..|.|
WSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQ-SCLDPEGIDLLMQMLQYDPQK

RISAKEALNHPWI
||||||||.||..
RISAKEALQHPYF
Kinase B0285.1.AA PITSLRE 311-605 43 4.1e-112 378.78 In-house 1-295 (295) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-295/295
Sequence Identity: 43% (132 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLE--NEKEGFPITAIREIK-ILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGL
.  |..|.||||| ||.|.. .|.| |||||. .|   ||||||||..|||. ||. | | ||| .  ||.    ||.        |.|.|||.||| .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGS-NMDKI-------YMVMEYVEHDLKSL

LESKE--LVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWS
.|        |   .| .|  ||| | .. |    .||| |.||.| ..|| |||.| |||| .    . ||  |.||||| |||||| . | ...|.||
MENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWS

TGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFR-MKRTYQRRIREEFE--HIMPREAVDLLDKMLTLNPEKRISAKEALNH
 || ..|. | ||||.|..|  |.. | |  | |.   ||  ||| .|. .  ..       |. |         . ||| .|||.||..||.| .|| |
VGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKH

PWI
|| 
PWF
Kinase B0285.1.AA CDK5 311-605 44 1.6e-108 344.13 In-house 1-287 (287) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-287/287
Sequence Identity: 44% (132 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLES
|  .. ||||||| |||| |  |.| ||||||||..| || | |||||| .|. | ||||||| |..           .     ||||..| ||   ..|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVI----------HSEKKLTLVFEFCDQDLKKYMDS

KELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCML
 .  . ... | |.  ||| |||. |.   |||| |  | |.| .|||| || ||||      | |.  |.|||||||  |.|   |   ||.|| || .
CNG-EMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIF

GELF-TRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWN-TFRMKRTYQRRI-REEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWI
 |.  . .||| ||..  || .| |. |.|..|.|| .|.|  ..        |. .   ..  . .  .  ||| ||| .||..|||||.||.||. 
AEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase B0285.1.AA CDK9 311-605 40 5.70000000001e-107 361.69 In-house 1-340 (340) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-340/340
Sequence Identity: 40% (138 aa)

YTMLDQIGEGTYG-----------QVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEY
|  |  || ||.|            |.||    ..  ||.|.| .||||||||||| ||||.| .| | |.| |. |     .     . || |||||..
YEKLAKIGQGTFGQVLQGRKSRNSEVFKARHKKNKRMVAMKKVLMENEKEGFPITALREIKMLQLLKHENVVNLIEICRTKATAYNRYKDRATFYLVFDF

VDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLW-----EKESR-LYTNRVITLWYRPPELLLG
 .||| ||| |  .| |    | .. ..|. || |||    |||| |  |.|.   | || || ||||       .   | ||||||.||||||||||||
CEHDLAGLL-SNMNVKFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDGILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLG

DERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTF------RMKRTYQRRIREEFEHIMP------------
|  |||.||.|  || . |. || |   || |  || |||. ||| . | || . ..  ||.        . .   |....     |             
DRNYGPPIDMWGAGCIMAEMWTRSPIMQGNTEQHQLQLISQLCGSITPDVWPNCENMELWNKMSSEPNSELPKGQKRKVKDRMKNYMKFDAPDSKTDPFG

-----------REAVDLLDKMLTLNPEKRISAKEALNHPWI
            .|..|.||.|.. |.||. . |||.| | 
KNVKQHDSATDQQACHLIDKLLNIDPKKRMDSDEALDHDWF
Kinase B0285.1.AA Pkinase 311-605 31 3.7e-99 340.53 Pfam 1-293 (293) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-293/293
Sequence Identity: 31% (100 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIR--EIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDH-----D
|. . .||.|..|.|||...  ||..||.|......||.....|..|  ||.|.. |.|.||||| |.. |          . . |.|.||...     |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----------KDHIYMVMEYCEGGLYVMD

LIGLLE---SKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGEL----KIADLGLARLW-EKESRLYTNRVITLWYRPPELLLGDE
|  ...   .. .  |  ..... ..|.|.||.|.|. |..|||.| .|||..|.|..    ||.| |||..  .  .. .| .. |.||..||...|..
LFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQ

RYGPAIDVWSTGCMLGELFTRKPLFNGN----NEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPE
 |||..|.|| ||.| |.....|.| |     |   |...| .. | |.  .||.. .    . ||  .    . ...| | ...|. |.....|...|.
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPK

KRISAKEALNHPWI
||..|...|.|||.
KRPTAEQILQHPWF
Kinase B0285.1.AA S_TKc 311-605 29 5.9e-98 332.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-231/231
Sequence Identity: 29% (91 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDH---DLIGL
|..|..||.|..|.|||.... ||..||.|...         ....|||.||.. ||.|||.| |.  |            ..|.|.||.|.   ||  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDY

LESKELVD----FNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGP-AID
....        |.  .......|....|.|.|. |..|||.| .|||...  ..||.| ||||.        |  . |.||..||.|     ||. ..|
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCD

VWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALN-
.|| ||.| |.....|.|       |.... |..|                                     ..|| |...|.|. .||||..| |||. 
WWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HPWI
      |||.
EWDIKCHPWF
Kinase B0285.1.AA CDK-Unclassified 311-605 30 1.3e-91 301.62 In-house 1-324 (324) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-324/324
Sequence Identity: 30% (101 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKE----------GFPITAIREIKILRQLHHKNIVRLMDIVIDDISMD------ELKRTRANFY
| |.  .||||.| |.||   .|  .|| |.. . |.|            ..||. |||..|....|.||  .||.. |   .        | .    ||
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPS---FY

LVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKG-----ELKIADLGLARLWE------------KESRLYT
.| ||.. .. . |.. .     . ||   ..|.|||.||.|  .. ||||| .||.. |..      ||||| |.|.. .            .....|.
MVMEYMPYTWYNQLHN-NRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYS

NRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIREEFEHIMPRE
  | | ||| ||||.|.  |....|.|| || . |.| .||.| |..|  |.  |.|. |.|. |.||... . . .  . |    ..  ..|       
TQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKHAS

AVDLLDKMLTLNPEKRISAKEALNHPWI
  ...  |. ..| .| .. |.| |||.
ENNCEFQMVMYQPYNRWKCMEILQHPWF
Kinase B0285.1.AA MAPK 311-605 33 6.1e-91 308.43 In-house 1-328 (328) Show / Hide 
Range on Protein: 311-605
Range on HMM: 1-328/328
Sequence Identity: 33% (111 aa)

YTMLDQIGEGTYGQVYKAVNNL------TGEQVALKRVRLENEKEGFPITAIREIKILRQL-HHKNIVRLMDIVIDD-----ISMDELKRTRANFYLVFE
|. | .||.| ||.| .|. ..      .|..||.|..    ... .   ..||||.|| . ||.||..| ||   .      |..|..     .|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFN----DIYIVME

YVDHDLIGLLESKELVDFNKDQICSLFKQLLEG--LAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKES--------------RLYTNRVIT
. ..||  ...|      . | |.... |.| |  | |||  . .|||.| ||||||  ..|||.| |||| .. |.              .  |  | |
LMETDLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVAT

LWYRPPELLLGD--ERYGPAIDVWSTGCMLGELFT-RKPLFNGNNEFGQLELISKVCGSPNVDNWPELT-ELVGWNTFRMKRTYQRRIREEFEHIMP---
 ||| ||..|.    .|  |.|.|| || ..|. | ||||| |..   |..|| .|.|.|  . .  ..     .| ..    .... .  .|.. |   
RWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNAN

----REAVDLLDKMLTLNPEKRISAKEALNHPWI
    ..|.|||.|||...|.|||...|||.|| .
FNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase B0285.1.AA CDK-DD1 311-554 42 1.3e-80 248.57 In-house 1-234 (379) Show / Hide 
Range on Protein: 311-554
Range on HMM: 1-234/379
Sequence Identity: 42% (104 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFP-ITAIREIKILRQLHH-KNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLL
|  .  .|.|.|| |.||. ..| . ||||..   |. .| |      |.| | || | |||| | |.   .   ...        .||||  ||| ...
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEPKV----ECKYLMQLRHCKNIVHLIDHFYNF-KNSKY-------VMVFEYFEHDLWKFM

ESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEK-ESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTG
 |         .|   |.|||||.  .|| |  ||||| .| |.||.| |||.|.|..    |        .|..|||||||||.|   ||| ||.|| |
-SNHQCYMSLPCIKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVG

CMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWN
| | |. |   .| | ||  ||||| | || |   |||    | |.|
CILMEMITNFYMFAGSNEQQQLELICKLCGCPTEKNWPGVSQLQGYN
Kinase B0285.1.AA Pkinase_Tyr 311-468 29 1.1e-19 67.33 Pfam 1-160 (270) Show / Hide 
Range on Protein: 311-468
Range on HMM: 1-160/270
Sequence Identity: 29% (51 aa)

YTMLDQIGEGTYGQVYKAVNN----LTGEQVALKRVRLENEKEGFPITA------IREIKILRQL-HHKNIVRLMDIVIDDISMDELKRTRAN--FYLVF
 |.. ..||| .|.|||.. .     |. .|| | ..     ||    .      .||.||..|| ||.|||||. ...         . .     |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT---------DQGEPNQIYIVM

EYVDH-DLIGLLESK--ELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARL
||. | ||   | ..  .   ..  ....   |  .|..| .. .. |||. . |.||....  ||.| ||||.
EYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase B0285.1.AA CDK-DD1 579-605 62 2.1e-16 46.55 In-house 353-379 (379) Show / Hide 
Range on Protein: 579-605
Range on HMM: 353-379/379
Sequence Identity: 62% (17 aa)

VDLLDKMLTLNPEKRISAKEALNHPWI
.||. .||||.| |||..||||.||| 
LDLIERMLTLCPKKRINTKEALQHPWF
Kinase B0285.1.AA TyrKc 311-608 20 3.3e-16 39.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 311-608
Range on HMM: 1-280/280
Sequence Identity: 20% (68 aa)

YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQL--HHKNIVRLMDIVIDD----ISMDELKRTRANFYLVFEYVDH-D
 |.....||| .|.|||.. .   .||| | .. .          .||..|...|  ||.|||||  .....    ..           ..|.||..| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYI-------EPLMIVMEYMPHGD

LIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKE------SRLYT-----NRV--ITLWYRPPEL
|   | ...   .. .. .|   |  .| .|.|  .. |||. . |.||....  ||.| ||.| .. .      .  |.     ..   . .   .|| 
LKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVD------NWPELTELVGWNTFRMKRTYQRRIREEFEHI----MPREAVD
.  . .. .. |||| | .. |.||.                   ...|  .      .. |. |.|     ...  .        . .    .| |  .
I-NYGKFTTKSDVWSFGVCMWEIFTY-------------------GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY------P-MSFVCCPDEMYQ

LLDKMLTLNPEKRISAKEALNHPWIRSL
.  .    .||.| . .|      .. .
IMKQCWHEDPEDRPTFSEI-----HECF