Gene C05D10.2 (Nematode worm)

C05D10.2

Species: Nematode worm
Alias: CE29020, C05D10.2, aSWK191, C05D10.2a
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: III:-1.39, WormBase Physical Map location: III: 6063334-6067555,

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
C05D10.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 294 Kinase domain by global Sugen HMM Fasta, JSON
C05D10.2.AA Protein Genbank 470 None Fasta, JSON

Protein domain

Protein domains of C05D10.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C05D10.2.AA ERK7 13-306 68 3.7e-217 727.72 In-house 1-292 (292) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-292/292
Sequence Identity: 68% (200 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIKKGSILKDV
....||||||||||||||||||....||||||||||||.||.||||||.||||||..|||.|.|.|..||||||||||.|||||.|||.||.||.||||.
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGCILA
||||||.||.|||...|||||.||||||||.|||..|.||..|||||||....|.|  ....|.|||||||||||.|||||...||||||||||.||||.
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEY--DEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

EMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPYV
|||.|...|||.||.||||.|..||.||...||..||||||...||.|.|..||.|| ...|....|||...|||.|.|.||||.||.| ||||
EMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase C05D10.2.AA MAPK 13-306 42 7.89999999999e-169 567.17 In-house 1-328 (328) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-328/328
Sequence Identity: 42% (139 aa)

FDLQKRLGKGAYGIVWKAYDKR------SRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRAD-----ND----RDIYLAFEFMEA
....|..|.||||.|..|.|||      . ..||.|||...|.|||. .||.||...|..|..|.|.|||..||...     |.    .|||. .|.||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHNVIKKGSILKDVHKQYIMCQLFRAIR--FLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMP------DLTEYVATRWYRSP
|||..|| . .| | |.||.| |. |...  ..||.||.||||||||.|.. .| .|..|||||||. . . ....|..|      ..||||||||||.|
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILLA--AKRYTKGVDMWSLGCILAEMLI-GRALFPGSSTINQIERIMNTIAKPSRADIASIG-SHYAASVLEKM---PQRPRKPLDLIITQ----SQTA
||.|   ...|||.|||||.|||.||||  .. ||||...|.|...||... .||. .|  |. |. |..... .   |..|.||.. ..       .  
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

AIDMVQRLLIFAPQKRLTVEQCLVHPYV
|||.....| | |.||.|||..| |||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase C05D10.2.AA CMGC 13-306 23 3.9e-130 430.19 In-house 1-513 (513) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-513/513
Sequence Identity: 23% (121 aa)

FDLQKRLGKGAYGIVWKAYDKRSR--------------ETVALKKIFDAFRNPTDSQ----------RTFREVMFLQEFG----------------KHPN
..  |..|.|.||.|.|..|||.               | ||.|||. .| .... .          |..||...|...                 .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VIKLYNIFRADN---------------DRDIYLAFEFMEADLHNVIKKGS---------ILKDVH------------KQYIM------CQLFRAIR--FL
..|||.||. .|               ....|| ||.|. ||...||. .          |.. |            ..|.|       |..|..   ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSGN--VLHRDLKPSNVLLDADCRV--------------------KLADFGLARSLSSLEDYPEGQKMP-------------DLTEYVATRWYRSPEILL
|| .  ..||||||.|.|.. .|..                    |..||||||.... .| ...|...              .|.||.|||||.|||||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

AAKRYT---------KGVDMWSLGCILAEMLIG--------RALFP-----------GSSTINQIERIMNTIAKP----------------SRADIASIG
 .|.||         ...||||.|||.|||. |        . |||           |.|.|.|...|.... .|                .. ..  |.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------SHYAASVLEK---MPQRPRKPLDLIITQSQ-----------------------------------TAAIDMVQRLLIFAP
                    |. |   ...    |..|.||.  ..  ..                                     ||| ....|.. |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

QKRLTVEQCLVHPYV
.||.|.||.| ||| 
DKRITAEQALQHPYF
Kinase C05D10.2.AA ERK 13-306 42 9.20000000001e-109 367.63 In-house 1-307 (307) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-307/307
Sequence Identity: 42% (132 aa)

FDLQKRLGKGAYGIVWKAYDKR-----SRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRAD---NDRDIYLAFEFMEADLHNVIK
. . |..|.||||.| .| ||      ....|| |||..|| .| .  || ||  .|  | .|.|.|.|..|.. .   .  |||. .|.|| ||| .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

KGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLAR----SLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTK
    | | | || | |. ... ..|| ||.||||||||.|.  .|  | .||||||    | .. .        ...||||||||||.|||.| .. |||
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHE----CNQNFMTEYVATRWYRAPEIMLSWQKYTK

GVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKP-SRADIASIGSHYAASVLEKMPQ--RPRKPLDLIITQ--SQTAAIDMVQRLLIFAPQKRL
 .|.|| |||.|||| .. |||| ....||.|| ..| .| |  |.  |.|  |   . ..|   || ||.  |.        |||  ...| | |.||.
AMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRI

TVEQCLVHPYV
|||.|| ||| 
TVEECLEHPYF
Kinase C05D10.2.AA S_TKc 13-306 27 3.3e-97 330.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-231/231
Sequence Identity: 27% (87 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRADNDRDIYLAFEFMEA---DLHNVIKKGSI-
... . .||||.| |.|...|.. . ||.|.|          ... ||.  |..  .|||..||| .|.     ..|. .|...    ||. .|||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTK-GV
     .   | ...|.|...|. ..|| ...||||||.|.|||   ..|..|||||| |               | .. |.||..||.|     |.|  .
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----GYGKCKC

DMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLV
|.||.||||.||| |. .||      |...... |                                         |.|.....| . |.||.|. ..| 
DWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------HPYV
       ||..
DEWDIKCHPWF
Kinase C05D10.2.AA p38 13-306 37 4.3e-96 325.54 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-289/289
Sequence Identity: 37% (114 aa)

FDLQKRLGKGAYGIVWKAYDKRSRET---VALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRA-----DNDRDIYLAFEFMEADLHNVIK
.   . .|.|||| | ||.|.|...    || ||..  |  . .  ||.||.  |.   .| |||.| ..|       .. .|.|.  .||.|||.|..|
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHM-RHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

KGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDM
    | | | |..  |. |. .. || .. ||||||||. .  || ..  ||||||           ..  ..|.||||||||.|||.|   .||. ||.
CQR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-----------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDI

WSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHP
||.|||.||.. ||.||||.  |.|..|||. . .|..  .. | |. | .... .||.||. .  . ..    |||   ..|.  | ||.|.|. . ||
WSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHP

YV
| 
YF
Kinase C05D10.2.AA CDK 13-306 29 1.5e-91 293.17 In-house 1-284 (284) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-284/284
Sequence Identity: 29% (96 aa)

FDLQKRLGKGAYGIVWKAYDKRSR-----ETVALKKIF----------DAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRADN---------DRDI
..  ...| |.||.| || ||..      . ||||||           . |     .. . ||.  |.|   |||..||. ..  .|         .. .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGF-----PITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKL

YLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCR-----VKLADFGLARSLSSLEDYPEGQK-MPDLTEYVA
|. ||.|. ||  ...          . .| || |.. ..|| ...||||||.| |.. .       .|.|||||||  .. ..  .. . .  .|  | 
YMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQ--MS-EPNRTYTHEVV

TRWYRSPEILLAAKRYT--KGVDMWSLGCILAEMLI---GRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQT
|.|||.||.|| .|.|.   ..||||.|||.|||.    ...||||.| |.|...| ...  |.  .  .. .                           
TLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------

AAIDMVQRLLIFAPQKRLTVEQCLVHPYV
   |  ...| . |.||.. ||.| ||| 
---DLLNKMLCYDPKKRISAEQALQHPYF
Kinase C05D10.2.AA ERK1 13-306 43 1.3e-89 304.05 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-289/289
Sequence Identity: 43% (128 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRA---DNDRDIYLAFEFMEADLHNVIKKGSIL
.   . .|.||||.|  |||.. .. ||.|||   |   |  ||| ||.  |. | || |.|.. .| ||   .. ||.|.  . || ||  ..|   . 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRF-KHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

KDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGC
 | |  | . |. | ....|| |||||||||||.||   | .|. ||||||    . | ||      ||||||||||| |||.| .| ||| .|.|| ||
ND-HICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR----IAD-PEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGC

ILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPYV
||||||  | .|||   . |.  |.  .  ||..|.  |  . | . |. .| .|. |.. .  ..   |.|.....| | |.||.|||. | |||.
ILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase C05D10.2.AA Pkinase 13-306 27 1.5e-84 292.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFR--EVMFLQEFGKHPNVIKLYNIFRADNDRDIYLAFEFMEA-----DLHNVIK-
. . ...|.|..| |.|...| ....||.|.|    ...   |. .|  |.  .... .|||...|| .|.   ...||. .|..|      ||. .|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-KGSIL--KDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRV----KLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKR
 ..  .   . . . .| |..|.. ..|| ...||||||.|.|.| .. .    |..|||||. ..         . . .| .. |.||..||... .. 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQY

YTKGVDMWSLGCILAEMLIGRALFPGS----STINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQK
|.. |||||.||||.||| || .|||.    . ..|...| ..  .| . |.    | .  . .   . .  . . .  .    ...| . ..| . |.|
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKK

RLTVEQCLVHPYV
|.| ||.| ||..
RPTAEQILQHPWF
Kinase C05D10.2.AA ERK5 13-306 36 7.6e-84 284.87 In-house 1-295 (295) Show / Hide 
Range on Protein: 13-306
Range on HMM: 1-295/295
Sequence Identity: 36% (109 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRADND----RDIYLAFEFMEADLHNVIKKGSI
..   ..| ||||.|  |  ..  . ||.|||  ||   |  .|||||.  |. | .| |.| . .| .        .|.|  |. ||.||| .|     
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHF-RHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLG
.   |  | . |. | ....|| .|.||||||||.|    | .|. |||.|| |. .   |. ..|  .|||||||||| ||.... . ||. .|.|| |
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTF--SPDKHQM-FMTEYVATRWYRAPELMFSSHDYTQAIDVWSVG

CILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEK-MPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCLVHPYV
||. ||.  | .|||   |.|.. ||  .  |. . | ....      . | .|.|  |... .  .    |.|.. |.|.| | .|.|| . | ||..
CIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase C05D10.2.AA CDC2 13-233 35 2e-73 224.91 In-house 1-221 (301) Show / Hide 
Range on Protein: 13-233
Range on HMM: 1-221/301
Sequence Identity: 35% (83 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQR------TFREVMFLQEFGKHPNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIK--
.   ...|.| ||.| |. |... . ||||||    |  ...        . ||   |.|   |||..||  ..     . .|. ||... || .  .  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI----RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMS

--KGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLT--EYVATRWYRSPEILLAAKRYTK
  |.. .     . .| |. ... |.|.  ..||||||.| |.|.. ..|.|||||||  .    .|    .  .|    | |.|||.||||| .|||. 
IPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFG----IP----IRTYTTEHEVVTLWYRAPEILLGCKRYST

GVDMWSLGCILAEM---LIGRALFPGSSTINQIERI
.|||||.|||.|||      ..||.| | | |. .|
PVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKI
Kinase C05D10.2.AA MAPK-Unclassified 13-161 38 1.7e-52 180.76 In-house 1-158 (575) Show / Hide 
Range on Protein: 13-161
Range on HMM: 1-158/575
Sequence Identity: 38% (62 aa)

FDLQKRLGKGAYGIVWKAYDKRS-RETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRADNDRD-----IYLAFEFMEA---DLHNVI
 ..|| .| ||||.| .| ||..    || ||.  .| |.||  |. ||.  | .   |||.|.. .||... .       ||.  ..|.    ||| .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYL-NHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

KKGS-ILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARS
|     . . | ||.. |. | .  ||| ...||||||||.|.. || |. .|||..||
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRS
Kinase C05D10.2.AA MAPK-Unclassified 176-306 29 2.8e-38 133.5 In-house 404-575 (575) Show / Hide 
Range on Protein: 176-306
Range on HMM: 404-575/575
Sequence Identity: 29% (51 aa)

DLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIG-----------RALFPGSS--------------------TINQIERIMNTIAKPSRAD
..|.||.||||| |||.|  . |.. ||.||.|||.|||..            | ||||..                     . ||  |      |   |
HMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEED

IASIGSHYAASVLEKMPQRPRKPLD-LIITQSQ---------TAAIDMVQRLLIFAPQKRLTVEQCLVHPYV
.  |..  |   ..   . .. . . |.  .             .||.|| .| | |.|| | .| | |||.
CNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase C05D10.2.AA Pkinase_Tyr 13-168 28 5.4e-20 68.33 Pfam 1-166 (270) Show / Hide 
Range on Protein: 13-168
Range on HMM: 1-166/270
Sequence Identity: 28% (48 aa)

FDLQKRLGKGAYGIVWKAYDK----RSRETVALKKIFDAFRNPTD--SQRTFREVMFLQEFGKHPNVIKLYNIFRADNDR-DIYLAFEFMEA-DLHNVIK
  . | ||.||.| |.|.. |      . .|| |..      . .  ..  .||.  . ..|.|||...|| .   . .   ||. .|.|.  ||..  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----GSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDY
|    .  |.  ..  .  |  ..  .|.| |  ||||   |.|.. .  || .|||||| .   .||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDY
Kinase C05D10.2.AA TyrKc 13-309 22 4.9e-15 20.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-309
Range on HMM: 1-280/280
Sequence Identity: 22% (74 aa)

FDLQKRLGKGAYGIVWKAYDKRSRETVALKKIF-DAFRNPTDSQRTFREVMFLQEFG-KHPNVIKLYNIFRAD-----NDRDIYLAFEFMEA-DLHNVIK
  | | || ||.|.|.|.  |   ..|| |..  ||       .   ||   . ..| .|||...|| . . .      .  ... .|.|.  ||.. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KGSI-LKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSL-------EDYPE----GQK--MPDLTEYVATRWYRSPE
|    |.  .. ... |  .  ..||| |. ||||   |.|.... .|| .||||.| . .        . |      | |  .|        ||. .||
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP-------IRWM-APE

ILLAAKRYTKGVDMWSLGCILAEML-IGRALFPG-----SSTINQIERIMNTIAKPSRAD---IASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAID
 .   ...|   | || |  . |..  |    ||      | .  ||....    |  ..   ..                            . ..  .
CI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------FVCCPDE

MVQRLL---IFAPQKRLTVEQCLVHPYVVQF
| |  .    . | .| | ...     . .|
MYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase C05D10.2.AA CDC2 279-306 39 7.5e-09 22.78 In-house 274-301 (301) Show / Hide 
Range on Protein: 279-306
Range on HMM: 274-301/301
Sequence Identity: 39% (11 aa)

AIDMVQRLLIFAPQKRLTVEQCLVHPYV
.||  ...|.  ||||..... | ||| 
GIDLLMQMLQYDPQKRISAKEALQHPYF