Gene C45G9.1 (Nematode worm)

C45G9.1

Species: Nematode worm
Alias: aSWK085, YQI1_CAEEL, C45G9.1extended-stillmissGXGXXG, C45G9.1, CE24851
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: III: 5070195-5071465, WormBase Genetic Map location: III:-2.26,

Classification

Group: CK1
Family: TTBKL

Sequence

Name Sequence Type Origin Length Description Download
C45G9.1.AA Protein Genbank 290 None Fasta, JSON
C45G9.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 308 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of C45G9.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C45G9.1.AA TTBKL 1-231 44 1.9e-116 393.19 In-house 46-288 (288) Show / Hide 
Range on Protein: 1-231
Range on HMM: 46-288/288
Sequence Identity: 44% (110 aa)

MEDHVLKKLNANGPAPHIPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKD-SE
|| |||.||. ....||.|.. ..||......|||||.|.||||| ... . . .||.|||||.|||..||||..| .||||| |  .|  .|.... .|
MEVHVLMKLQ-PNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKK-RFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCE

RAKIIHILDFGLGRPFARYHA------RENKWIVRIARH---SAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQTDYRRGRVEQMK
|.......|||. | .|. ..      .||||..| .|    .|.|||..||.|||.|.||||||.|| ||. |.||||..|  |||.    . ..|.||
RCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG--LPWTNMEDKMEIEHMK

LNLTPKDVMSD------MPACMDKLMPHLASLNYYQRPDDHMIFKCF
.|.. .|...|      .| ...| |.|| ||.||.||| .||..||
KNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase C45G9.1.AA CK1 1-227 31 5.3e-79 268.76 In-house 55-339 (339) Show / Hide 
Range on Protein: 1-227
Range on HMM: 55-339/339
Sequence Identity: 31% (90 aa)

MEDHVLKKLNANG------------------PAPHIPNLNLYGKKMNFS-YMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHYNGFI
||.....|.  .|                  . ||.. .  .|.. ..  ||||||||.||.||  .|.  |. || .|| ...|| ..||.|.| .|||
MEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFI

HRNVNTQNLFLGNEKD----------SERAKIIHILDFGLGR-PFARYHA-------RENKWIVRIARH---SAEFRG-SFRYASPNVHLRKEQGRVDDV
||..  .|. .| ...          ..........|||. |  ... ..       |...|. | .|     . |||  .||.|.|.||.|||||.||.
HRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDL

WSLPYVIIELNGGKA-LPWQTDYRRGR-----VEQMKLNLTPKDVMSD------------MPACMDKLMPHLASLNYYQRPDDHMI
||. |..||.. |.. |||| . .  .     ||.|| . . .. ||.            .| .. |.|... ||.|| ||| .||
WSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase C45G9.1.AA TTBK 1-227 35 3.3e-39 136.23 In-house 44-257 (257) Show / Hide 
Range on Protein: 1-227
Range on HMM: 44-257/257
Sequence Identity: 35% (80 aa)

MEDHVLKKLNANGPAPHIPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKDSER
||  |||||      .|.      |   .| ||||.|.|.|| ||          || .|  |.|.| . ... .|  || || .   |  .|  . ...
MEVAVLKKLQG---CDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQ--PRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMG--RNPST

AKIIHILDFGLGRPFARYHARENKWIVRIARHSAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQTDYRRGRVEQMKLNLTPKDVMS
 ... .||||| | .   .       || .|..| |||  |||| | |. .| || || ||| |. .|   |  |||     .  | .||     .. . 
CRKCYMLDFGLARQYTNACGE-----VRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQ-LPWRKIKDKDQVGEMKEKYDHRMLLK

DMPACMDKLMPHLASLNYYQRPDDHMI
..|  .   | |..||||  |||  .|
HCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase C45G9.1.AA Worm6 1-227 31 2.7e-34 120.27 In-house 47-279 (279) Show / Hide 
Range on Protein: 1-227
Range on HMM: 47-279/279
Sequence Identity: 31% (75 aa)

MEDHVLKKLNANGPAPHIPNLNLYGKKMN--FSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNE--K
||  |||...  . ..| ...  .||. |  | |.||||.|.||.||    .  .. || ||  ...||   |.  .| .|||||.|  .|   |    |
MECMVLKAVKHHK-CRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLR--KNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMK

DSERAKIIHILDFGLGRPFARYHARENKWIVRIAR-HSAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQTDYRRGRVEQMKLN--L
...  ..| .||||. |   |. .....  .|  | . ..||| .|||. . | ..||.| ||. |  |...|.  |  |||.   .. .||. |     
EDNEHHTIYMLDFGMCR---RKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVG-CLPWRHMKDHDHVEKHKKWCRR

TP-----KDVMSDMPA-CMDKLMPHLASLNYYQRPDDHMI
.      ...    |.  ... |  . ...|. |||   |
RTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase C45G9.1.AA CK1-D 18-227 30 3.4e-22 74.98 In-house 57-261 (261) Show / Hide 
Range on Protein: 18-227
Range on HMM: 57-261/261
Sequence Identity: 30% (67 aa)

IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFAR
||..  .|.  ..  ||| |||  | ||   |.   | ||  |   .. | .  ..|.| . |||| .   |  .|  |   | ....|.|||| .   |
IPEIRWCGQEGDYNVMVMDLLGPSLEDL--FNYCHRK-FSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGK---RGNMVYIIDFGLAK---R

YHARENKWIVRIA-RHSAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ------TDYRRGRVEQMKLNLTPKDVMSDMPACMDKLM
|  |. .    |. |   .  |  |||| | |.  || | ||. || ||..  | | .||||         .  |. . |..   ... . .|    . |
Y--RDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRG-SLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYM

PHLASLNYYQRPDDHMI
 .  .| . ..||   .
NYCRNLKFDDKPDYCYL
Kinase C45G9.1.AA CK1-A 18-178 34 2.6e-20 68.37 In-house 57-206 (261) Show / Hide 
Range on Protein: 18-178
Range on HMM: 57-206/261
Sequence Identity: 34% (56 aa)

IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFAR
||..  ||.  ..  ||| |||  | ||   ||   . |.  |   .  | .  . |||  .|||| .   |  .| ..   .   ....|||| .   .
IPHMRWYGCEKDYNVMVMDLLGPSLEDL--FNFCKRR-FTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNK---LFLIDFGLAK---K

YHARENKWIVRIARHSAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ
|.  . .  .   |.  .  |  |||| | ||  || | ||. |. ||..  | || ||||
YRDSRTRQHIPY-REDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGK-LPWQ
Kinase C45G9.1.AA CK1 5-111 30 6.6e-10 30.48 In-house 49-155 (271) Show / Hide 
Range on Protein: 5-111
Range on HMM: 49-155/271
Sequence Identity: 30% (34 aa)

VLKKLNA---NGPAPHIPNLNLYGKK--MNFSYMVMTLLGRNLQDLESTNFV-VNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKDS
..| |.    ......||..  .|.    .. .|||.|||..| ||    |   |. ||  |   .. | .  . |||...|||| .   |   |     
IYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDL----FNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR--YG

ERAKIIHILDFGL
 ......| ||||
KHCHQVYIIDFGL
Kinase C45G9.1.AA CK1-G 33-178 34 5e-09 26.66 In-house 73-209 (266) Show / Hide 
Range on Protein: 33-178
Range on HMM: 73-209/266
Sequence Identity: 34% (50 aa)

MVMTLLGRNLQDLESTNF-VVNKGFSRGTWSRVGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIAR
||| |||  | ||    | . .  ||  |   | || .  ..|||    | | |   |   |  . ......||| |||. . .     . .. |    .
MVMDLLGPSLEDL----FDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGR-PSNKDQHVIHIIDFGMAKQYI--DPETKQHIPYREH

HSAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ
 |    |  || | | || .|| | ||  .|  . .    |. ||||
KS--LTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGS-LPWQ
Kinase C45G9.1.AA Dual 64-159 30 3.8e-08 23.36 In-house 118-206 (282) Show / Hide 
Range on Protein: 64-159
Range on HMM: 118-206/282
Sequence Identity: 30% (30 aa)

VGIQWVYALKYVHYNGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHAR-ENKWIVRIARHSAEFRGSFRYASPNVHLRKEQGRVDDV
|.|| . |... |  |..|||..  |   | .   ..   .  .||..    .| .   |||  .|.||    . |  |||.    . |.||| ||.
VAIQMLRAIQDLHSIGYLHRNIKPANFHCGLG---MDETTVYMQDFRI----VRKYIDPENK-KHRTARKKVKMYGCGRYACRACMMQKDQGRKDDL
Kinase C45G9.1.AA CK1-Unclassified 5-45 27 1.6e-07 18.26 In-house 47-93 (244) Show / Hide 
Range on Protein: 5-45
Range on HMM: 47-93/244
Sequence Identity: 27% (13 aa)

VLKKLNANG-----PAPHIPNLNLYGKK--MNFSYMVMTLLGRNLQDL
... |. .      .  .||..  .|.    .. .|||.|||..| ||
IMQYLQNGHNCDNFI-KGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDL
Kinase C45G9.1.AA CK1-Unclassified 141-178 57 2e-06 15.32 In-house 181-217 (244) Show / Hide 
Range on Protein: 141-178
Range on HMM: 181-217/244
Sequence Identity: 57% (22 aa)

RYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ
|||| | || .||.| ||  || ||.| .  |. ||||
RYASINAHLGIEQSRRDDLESLGYVLIYFLKGS-LPWQ
Kinase C45G9.1.AA S_TKc 1-231 17 3e-06 -84.53 SMART 18-231 (231) Show / Hide 
Range on Protein: 1-231
Range on HMM: 18-231/231
Sequence Identity: 17% (46 aa)

MEDHV-----------------LKKLNANGPAPHIPNLNLYGKKMNFSYMVMTLLGR---NLQD-LESTNF-VVNKGFSRGTWSRVGIQWVYALKYVHYN
  ..                  .. |      |.| .|  .    .. |||| ...    .| | ... .    ...|.  .  ..  | . ||.| | .
CRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH

GFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIARHSAEFRGSFRYASPNVHLRKEQGR-VDDVWSLPYVIIELNGGKALPW
|.||| .  .|..| .         | | |||| | .                    | |.  | .| |      |.   |.||.  ...|.      |.
GIIHRDLKPENILLDE--------HIKICDFGLARQL------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPF

QTDYRRGRVEQMKLNLTPKDVMSDMPACMDKLMPHLASLNYYQRPDDHMIFK---------CF
.        . .|. .         | . | .. ..   .  .||    ...          |
P-----QMQMMFKKIG--------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase C45G9.1.AA Pkinase 71-178 24 3.1e-05 19.6 Pfam 120-213 (293) Show / Hide 
Range on Protein: 71-178
Range on HMM: 120-213/293
Sequence Identity: 24% (27 aa)

ALKYVHYNGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIARHSAEFRGSFRYASPNVHL-RKEQGRVDDVWSLPYVIIEL
.|.| | .|.||| .  .|...  ...   | ...| |||| . |               .    | |. .|..| |.. ... |.  |.||.  ...|.
GLEYCHSMGIIHRDLKPENILID-NNGHIDA-CVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEM

NGGKALPWQ
  |. .|..
LCGR-PPFP
Kinase C45G9.1.AA CK1 141-178 55 3.2e-05 14.17 In-house 181-217 (271) Show / Hide 
Range on Protein: 141-178
Range on HMM: 181-217/271
Sequence Identity: 55% (21 aa)

RYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ
|||| | || .||.| ||  || ||.. .. |. ||||
RYASINTHLGIEQSRRDDMESLGYVLMYFLRGS-LPWQ
Kinase C45G9.1.AA CK1-Unclassified 74-112 35 0.012823 3.57 In-house 119-155 (244) Show / Hide 
Range on Protein: 74-112
Range on HMM: 119-155/244
Sequence Identity: 35% (14 aa)

YVHYNGFIHRNVNTQNLFLG-NEKDSERAKIIHILDFGLG
|.|...||||     |   |  .|   ......| ||||.
YLHNKNFIHRDIKPDNFLMGKLGK---NHHQVYIIDFGLS
Kinase C45G9.1.AA CK1 189-225 13 0.240701 0.63 In-house 234-271 (271) Show / Hide 
Range on Protein: 189-225
Range on HMM: 234-271/271
Sequence Identity: 13% (5 aa)

MKLNLTPKDVMSD-MPACMDKLMPHLASLNYYQRPDDH
.|..... .  ..  |. .  .. .  .|.....||  
KKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM