Gene C55B7.10 (Nematode worm)
C55B7.10
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
C55B7.10.AA | Protein | Genbank | 278 | None | Fasta, JSON |
C55B7.10.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 259 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of C55B7.10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | C55B7.10.AA | Worm6 | 12-270 | 40 | 1.4e-149 | 503.26 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-279/279 Sequence Identity: 40% (112 aa) YKLGPVLGDGGYGTVFLSQDDDIK----IAVKTEK----FSKSQLKIEIVVLKAAMQANCKHFCELVDCGTKGKD-FDYMMITLLGKDLHKLRCELPGRK .|.. .|.||.|.|....|.. | .|.| || .....||.|..||||... .|.|||...|.|..... | |...||.||.|. ||...|.|| WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK FSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGV---KSNRQSRTIFMYDFGLAR--KYIDKNNQVIPTR-KEVGWRGTTRYGSLNAHKRLDLGR || .|.|.|.||.|.|.|.||..||..||||||||..|. |......||.|.|||..| ||..|.|.... | ...|.|||.||..|..||. ...| FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR RDDLESWFYGLVEMTRGTLPWRNVVDRSSVQRAKEASHNTGR----TQFLFETPS-QYDKIFTIVDSYAFESAPDYKQI .||.||||| .|||..|.||||.. |...|.. |.. ... | ..|....| ....|....|.|.....||||.| KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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Kinase | C55B7.10.AA | CK1 | 12-270 | 29 | 5.3e-108 | 365.1 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-339/339 Sequence Identity: 29% (101 aa) YKLGPVLGDGGYG-TVFLS-----QDDDIK-------IAVKTEK-FSK--SQLKIEIVVLKAAMQAN---------CKHFCE----------LVDCGTKG .|.. .|.||.| .... | . . |.|.|. |. . ...| .......|.. .||||. ....| .. WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED KDFDYMMITLLGKDLHKLRC--ELPGRKFSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKS-----------NRQSRTIFMYDFGLAR-KYI . . || .||||..| .||. ...|||| .|.|.|.||.|.|.|..|..||. ||.||.||. |... |...|...| |||.|| ||. DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR DKNNQV------------IPTRK---EVGWRG-TTRYGSLNAHKRLDLGRRDDLESWFYGLVEMTRGT--LPWRNVVDRSS-----VQRAKEASHNT--- ||.... .| |. .|.|| |.|| |.|.|.. ..||||||.|||| |.|...|| |||.|. | . |...|...... DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM GRTQFLFETPS-------QYDKIFTIVDSYAFESAPDYKQI ...| . .|. .. ||.....|. ....|||. | STPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | C55B7.10.AA | TTBKL | 12-274 | 31 | 1.1e-71 | 241.24 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 12-274 Range on HMM: 1-288/288 Sequence Identity: 31% (91 aa) YKLGPVLGDGGYGTVF---LSQDDDIKIAVKTEKFSKSQ----LKIEIVVLKAAMQANCKHFCELVDCGTKGKDFDYMMITLLGKDLHKLRCELPGRK-F .. ..| ||.|.|. ..| . . |.| || ... .|.|. ||.. ...||......| . ||. .| ||.|..| .|| .| .| | WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKR-KDYNFMVMTLCGPNLQDLRKMMPNKKRF SINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKS--NRQSRTIFMYDFGLARKYIDKNN-----------QVIPTRK---EVGWRGTTRYGSLN | |..|||||.|.| ..|..||. |||||.|.. |... .. .|... |||.||.|..|.. .. . |. .. |||||| |.| SDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPN AHKRLDLGRRDDLESWFYGLVEMTRGTLPWRNVVDRSSVQRAKEASHNTGRTQFLF---ETPSQYDKIFTIVDSYAFESAPDYKQINKLL .| |...|| ||| ||.| ..|. | |||.|..|. . .|.... . . .. . ||. .|... . | . . ||| | ... MHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | C55B7.10.AA | TTBK | 12-270 | 38 | 3.2e-64 | 219.69 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-257/257 Sequence Identity: 38% (102 aa) YKLGPVLGDGGYGTVFLSQDDDIK---IAVKTEKFS--KSQLKIEIVVLKAAMQANCKHFCELVDCGTKGKDFDYMMITLLGKDLHKLRCELPGRKFSIN | | ||.| .. .| .. .|.| |. | ||.|. ||| .| |.| | . || .| || .|.|| | || . | .||. WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLK-KLQG-CDHVCRFIGCG-RNDKFNYMVMQLQGKNLADLRRKQPRGCFSLS TALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYIDKNNQVIPTRKEVGWRGTTRYGSLNAHKRLDLGRRDDLESWFYG |.||.|.| |.. |. | .|| ||.|| ||| | . . | ..| ||||||.|. .| | |. | ||| || | |||. ..||.||| | || TTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTC-RKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYM LVEMTRGTLPWRNVVDRSSVQRAKEASHNTGRTQFLFETPSQYDKIFTIVDSYAFESAPDYKQI ||| | |||| . |. | . || | . |.. . | .| |||. | LVEFVQGQLPWRKIKDKDQVGEMKEKYD---HRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | C55B7.10.AA | CK1-Unclassified | 12-220 | 33 | 1.6e-41 | 120.36 | In-house | 1-219 (244) | Show / Hide |
Range on Protein: 12-220 Range on HMM: 1-219/244 Sequence Identity: 33% (74 aa) YKLGPVLGDGGYGTVFLSQDD--DIKIAV----KTEKFSKSQLKIEIVVLKAAMQANC------KHFCELVDCGTKGK-DFDYMMITLLGKDLHKLRCEL |... .| | | ... . . . |. |. | .||..|. ... ..| . |.. . ||. . |...| .|||..| .| . YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSK--HPQLCYEAKIMQ-YLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC PGRKFSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYI--DKNNQVIPTRKEVGWRGTTRYGSLNAHKRLDLGR .||||. | | |. | .. | ||. .|. || || || | |..... .... ||||. .|| ||... || | . .. ||.|| |.|||. . .| -NRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMG-KLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSR RDDLESWFYGLVEMTRGTLPWRNV |||||| | |. .|.||| |. RDDLESLGYVLIYFLKGSLPWQNI |
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Kinase | C55B7.10.AA | Dual | 64-274 | 29 | 5.6e-40 | 132.06 | In-house | 70-282 (282) | Show / Hide |
Range on Protein: 64-274 Range on HMM: 70-282/282 Sequence Identity: 29% (64 aa) KHFCELVDCGTKGKD-FDYMMITLLGKDLHKLRCELPGRKFSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYI |.| |.|| | .| |. . . | | | .| .. ..||.|.| || ||.. |..|| ||. |. . . |..| ||...|||| KCFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGL--GMDETTVYMQDFRIVRKYI D-KNNQVIPTRKEVGWRGTTRYGSLNAHKRLDLGRRDDLESWFYGLVE-MTRGT-LPWRNVVDRSSVQRAKEASHNTGRTQFLFETPSQYDKIFTIVDSY | .| .. . || | |. || . . | || ||||.| | . | . ..||. |. . .|.. . . ..| . .. |..| DPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGY AFESAPDYKQINKLL ..|.||| . | QYDSTPDYDYFRNCL |
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Kinase | C55B7.10.AA | CK1 | 12-220 | 33 | 1.6e-36 | 123.36 | In-house | 1-219 (271) | Show / Hide |
Range on Protein: 12-220 Range on HMM: 1-219/271 Sequence Identity: 33% (74 aa) YKLGPVLGDGGYGTVFLSQDDDI---K--IAVKT--EKFSKSQLKIEIVVLKAAMQAN-----CKHFCELVDCGTK-GKDFDYMMITLLGKDLHKLRCEL |..| .| | | ..| . . .|.| .| .||..|. ..| .| . |... . ||. .|...| ..|||..| .| . YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYK-ILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNF PGRKFSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYID-KNNQVIPTRKEVGWRGTTRYGSLNAHKRLDLGRR .||||. | | |. | .. | .| .|. ||.|| || |. ..... .... ||||| .|.| |..| || | .. ||.|| |.|.| . .|| CNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRR DDLESWFYGLVEMTRGTLPWRNV ||.|| | |. ||.||| .. DDMESLGYVLMYFLRGSLPWQGL |
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Kinase | C55B7.10.AA | CK1-D | 12-270 | 32 | 6.8e-34 | 116.89 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-261/261 Sequence Identity: 32% (86 aa) YKLGPVLGDGGYGTVFLSQD--DDIKIAVKTE--KFSKSQLKIEIVVLKAAMQANCKHFCELVDCGTKGKDFDYMMITLLGKDLHKLRCELPGRKFSINT |..| .| | .| ... .. . .|.| | | ||.|| . | || |. || | |. |.. ||| | | .||||. | YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYK-MMQGGI-GIPEIRWCGQEG-DYNVMVMDLLGPSLEDL-FNYCHRKFSLKT ALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYIDKN-NQVIPTRKEVGWRGTTRYGSLNAHKRLDLGRRDDLESWFYG | .. | .. | .| |. ||.|| || |. .. .... |||||..| | . | || | . || || |.| |. .. ||||||| | VLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGL--GKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYV LVEMTRGTLPW---RNVVDRSSVQRAKEASHNTGRTQFLFETPSQYDKIFTIVDSYAFESAPDYKQI |. ||.||| . . | .| | .| . ||.. . . . . |. ||| . LMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | C55B7.10.AA | CK1-A | 12-270 | 30 | 6.8e-32 | 109.91 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 12-270 Range on HMM: 1-261/261 Sequence Identity: 30% (81 aa) YKLGPVLGDGGYGTVFLS----QDDDIKIAVKTEKFSKSQLKIEIVVLKAAMQANCKHFCELVDCGTKGKDFDYMMITLLGKDLHKLRCELPGRKFSINT |.| .| | .| ..|. . ... | . .| || | | . . . | . .. | ..||. |.. ||| | | . |.|.. | YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYR--ILQGCVGIPHMRWYG-CEKDYNVMVMDLLGPSLEDL-FNFCKRRFTMKT ALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYID-KNNQVIPTRKEVGWRGTTRYGSLNAHKRLDLGRRDDLESWFYG | . | . | .| .|. ||.|| || |. .| .|. |||||.|| | . | || |.. || || |.||| .. ||||.|| | VLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYV LVEMTRGTLPWRNVVDRSSVQR---AKEASHNTGRTQFLFETPSQYDKIFTIVDSYAFESAPDYKQI .. ||.||| . |. | | | |... ... . . || .||| . MMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | C55B7.10.AA | CK1-Unique | 12-218 | 28 | 3.7e-31 | 105.27 | In-house | 1-233 (337) | Show / Hide |
Range on Protein: 12-218 Range on HMM: 1-233/337 Sequence Identity: 28% (67 aa) YKLGPVLGDGGYGTV----FLSQD----DDIKIAVKTEKFSKSQL----KIEIVVLKAAMQAN--CK---HFCELVDCGTKGKDFDYMMITLLGKDLHKL .. .| ||||.| |. || . . ||| . .. .|| |.|. || ||||. | . .| .. |..|. . . WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQH-RDWWWIVMTMHGPSMEEC RCELPGR-KFSIN------TALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARK--YIDKNNQVIPTRKEVGWRGTTRYGS |..... .| | .|.. | |.| . | | || |. ||.|. . | ....| |.| |. ...|.|. . |. . ||. .| . -CMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCP LNAHKRLDLGRRDDLESWFYGLVEMTRGT--LPWR |. ..|||||.||||| |. .| | |. CSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK |
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Kinase | C55B7.10.AA | S_TKc | 12-260 | 16 | 2.2e-10 | -24.73 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 12-260 Range on HMM: 1-231/231 Sequence Identity: 16% (48 aa) YKLGPVLGDGGYGTVFLSQDDD--IKIAVKTEKFSKSQLKIEIVVLKAAMQANCKHFCELVDCGTKGKDFDYMMITLLGK---DLHKLRCELPGRK---- |... ..| |..|.|.. .. . . |.| | ... || .|| .... . | |. |. || ... ||... .. .... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP FSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYIDKNNQVIPTRKEVGWRGTTRYGSLN------AHKRLDLGR |. .| .. |...| | .|. |.. ||.|| | .| ||||||.. || |... FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------------------TTFCGTPWYMAPEVL-------- RDDLESWFYG-----------LVEMTRGTLPWRNVVDRSSVQRAKEASHNTGR---TQFLFETPS---QYDKIFT-----IVDSYA . . | || | |.. . .. . .. . | |. .... . . ------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | C55B7.10.AA | Pkinase | 12-42 | 30 | 0.000625 | 14.98 | Pfam | 1-33 (293) | Show / Hide |
Range on Protein: 12-42 Range on HMM: 1-33/293 Sequence Identity: 30% (10 aa) YKLGPVLGDGGYGTVFLSQDDDIK--IAVKTEK |..| ..| |..|.|.. .. . |||. | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK |
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Kinase | C55B7.10.AA | TyrKc | 12-274 | 16 | 0.000692 | -159.79 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 12-274 Range on HMM: 1-280/280 Sequence Identity: 16% (50 aa) YKLGPVLGDGGYGTVFLSQDDDIKIAVKTEKFSKSQLKIEIVV-LKAAMQA--NCKHFCELVDCGTKG-----KDFDYMMITLLGK--DLHKLRCELPGR .|| .|| | .|.|.. . . |. |||. | .. . .. .. .. . .. |. . |.. . .|... . . ||.. . .. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK KFSINTALRIGIQTLKACEELHRIGFVSRDVKPGNFAPGVKSNRQSRTIFMYDFGLARKYIDK-----NNQVIPTRKEVGWR--GTTRYGSLNAHKRLDL .. . | . .| . .| ||. ... || | |..|. |. ||||.|. |. . ... .... | . | . -LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL--VGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA--------- GRRDDLESWFYG--------------LVEM-TRGTLPWRNVVDRSSVQRAKEASHNTGRTQFLFETPS--------QYDKIFTIVDS---YAFESAPDYK .|...|| . |. |.| |. ... . . ..|. .. . . |. |....| . . |. | . -----PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS QINKLL .| ... EIHECF |